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Items: 1 to 50 of 51

1.

Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.

Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, Chu K, Leborgne C, Dane AP, Haft A, Zhang Y, Zhang F, Morton C, Valentine MB, Davidoff AM, Nathwani AC, Mingozzi F, Grompe M, Alexander IE, Lisowski L, Kay MA.

Mol Ther. 2018 Jan 3;26(1):289-303. doi: 10.1016/j.ymthe.2017.09.021. Epub 2017 Sep 25.

PMID:
29055620
2.

ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer.

Drosos Y, Escobar D, Chiang MY, Roys K, Valentine V, Valentine MB, Rehg JE, Sahai V, Begley LA, Ye J, Paul L, McKinnon PJ, Sosa-Pineda B.

Sci Rep. 2017 Sep 11;7(1):11144. doi: 10.1038/s41598-017-11661-8.

3.

Modeling of the human alveolar rhabdomyosarcoma Pax3-Foxo1 chromosome translocation in mouse myoblasts using CRISPR-Cas9 nuclease.

Lagutina IV, Valentine V, Picchione F, Harwood F, Valentine MB, Villarejo-Balcells B, Carvajal JJ, Grosveld GC.

PLoS Genet. 2015 Feb 6;11(2):e1004951. doi: 10.1371/journal.pgen.1004951. eCollection 2015.

4.

Quantitative phosphoproteomic analysis identifies activation of the RET and IGF-1R/IR signaling pathways in neuroblastoma.

DeNardo BD, Holloway MP, Ji Q, Nguyen KT, Cheng Y, Valentine MB, Salomon A, Altura RA.

PLoS One. 2013 Dec 11;8(12):e82513. doi: 10.1371/journal.pone.0082513. eCollection 2013.

5.

Targeting oxidative stress in embryonal rhabdomyosarcoma.

Chen X, Stewart E, Shelat AA, Qu C, Bahrami A, Hatley M, Wu G, Bradley C, McEvoy J, Pappo A, Spunt S, Valentine MB, Valentine V, Krafcik F, Lang WH, Wierdl M, Tsurkan L, Tolleman V, Federico SM, Morton C, Lu C, Ding L, Easton J, Rusch M, Nagahawatte P, Wang J, Parker M, Wei L, Hedlund E, Finkelstein D, Edmonson M, Shurtleff S, Boggs K, Mulder H, Yergeau D, Skapek S, Hawkins DS, Ramirez N, Potter PM, Sandoval JA, Davidoff AM, Mardis ER, Wilson RK, Zhang J, Downing JR, Dyer MA; St. Jude Children’s Research Hospital–Washington University Pediatric Cancer Genome Project.

Cancer Cell. 2013 Dec 9;24(6):710-24. doi: 10.1016/j.ccr.2013.11.002.

6.

Th-MYCN mice with caspase-8 deficiency develop advanced neuroblastoma with bone marrow metastasis.

Teitz T, Inoue M, Valentine MB, Zhu K, Rehg JE, Zhao W, Finkelstein D, Wang YD, Johnson MD, Calabrese C, Rubinstein M, Hakem R, Weiss WA, Lahti JM.

Cancer Res. 2013 Jul 1;73(13):4086-97. doi: 10.1158/0008-5472.CAN-12-2681. Epub 2013 Mar 27.

7.

Regulation of p27Kip1 by Sox2 maintains quiescence of inner pillar cells in the murine auditory sensory epithelium.

Liu Z, Walters BJ, Owen T, Brimble MA, Steigelman KA, Zhang L, Mellado Lagarde MM, Valentine MB, Yu Y, Cox BC, Zuo J.

J Neurosci. 2012 Aug 1;32(31):10530-40. doi: 10.1523/JNEUROSCI.0686-12.2012.

8.

Stable human FIX expression after 0.9G intrauterine gene transfer of self-complementary adeno-associated viral vector 5 and 8 in macaques.

Mattar CN, Nathwani AC, Waddington SN, Dighe N, Kaeppel C, Nowrouzi A, Mcintosh J, Johana NB, Ogden B, Fisk NM, Davidoff AM, David A, Peebles D, Valentine MB, Appelt JU, von Kalle C, Schmidt M, Biswas A, Choolani M, Chan JK.

Mol Ther. 2011 Nov;19(11):1950-60. doi: 10.1038/mt.2011.107. Epub 2011 May 31.

9.

In vivo proliferation of postmitotic cochlear supporting cells by acute ablation of the retinoblastoma protein in neonatal mice.

Yu Y, Weber T, Yamashita T, Liu Z, Valentine MB, Cox BC, Zuo J.

J Neurosci. 2010 Apr 28;30(17):5927-36. doi: 10.1523/JNEUROSCI.5989-09.2010.

10.

Transgenesis in Xenopus using the Sleeping Beauty transposon system.

Yergeau DA, Johnson Hamlet MR, Kuliyev E, Zhu H, Doherty JR, Archer TD, Subhawong AP, Valentine MB, Kelley CM, Mead PE.

Dev Dyn. 2009 Jul;238(7):1727-43. doi: 10.1002/dvdy.21994.

11.

Rapid cell-cycle reentry and cell death after acute inactivation of the retinoblastoma gene product in postnatal cochlear hair cells.

Weber T, Corbett MK, Chow LM, Valentine MB, Baker SJ, Zuo J.

Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):781-5. doi: 10.1073/pnas.0708061105. Epub 2008 Jan 4.

12.

Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.

Inoue A, Li T, Roby SK, Valentine MB, Inoue M, Boyd K, Kidd VJ, Lahti JM.

Cell Cycle. 2007 Jul 1;6(13):1646-54. Epub 2007 May 8.

PMID:
17611414
13.

Translocations of 17q21 approximately qter in neuroblastoma cell lines infrequently include the topoisomerase IIalpha gene.

Yoon KJ, Danks MK, Ragsdale ST, Valentine MB, Valentine VA.

Cancer Genet Cytogenet. 2006 May;167(1):92-4. No abstract available.

PMID:
16682295
14.

Telomerase expression predicts unfavorable outcome in osteosarcoma.

Sanders RP, Drissi R, Billups CA, Daw NC, Valentine MB, Dome JS.

J Clin Oncol. 2004 Sep 15;22(18):3790-7.

PMID:
15365076
15.

An example of successful partnering.

Valentine MB.

Hosp Q. 2002 Spring;5(3):54. No abstract available.

PMID:
12090237
16.

Detection of MYCN gene amplification in neuroblastoma by fluorescence in situ hybridization: a pediatric oncology group study.

Mathew P, Valentine MB, Bowman LC, Rowe ST, Nash MB, Valentine VA, Cohn SL, Castleberry RP, Brodeur GM, Look AT.

Neoplasia. 2001 Mar-Apr;3(2):105-9.

17.

p27KIP1 deletions in childhood acute lymphoblastic leukemia.

Komuro H, Valentine MB, Rubnitz JE, Saito M, Raimondi SC, Carroll AJ, Yi T, Sherr CJ, Look AT.

Neoplasia. 1999 Aug;1(3):253-61.

18.

Lack of homozygously inactivated p73 in single-copy MYCN primary neuroblastomas and neuroblastoma cell lines.

Kong XT, Valentine VA, Rowe ST, Valentine MB, Ragsdale ST, Jones BG, Wilkinson DA, Brodeur GM, Cohn SL, Look AT.

Neoplasia. 1999 Apr;1(1):80-9.

19.

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN.

Teitz T, Wei T, Valentine MB, Vanin EF, Grenet J, Valentine VA, Behm FG, Look AT, Lahti JM, Kidd VJ.

Nat Med. 2000 May;6(5):529-35.

PMID:
10802708
20.

Hemizygous deletions of chromosome band 16q24 in Wilms tumor: detection by fluorescence in situ hybridization.

Shearer PD, Valentine MB, Grundy P, DeCou JM, Banavali SD, Komuro H, Green DM, Beckwith JB, Look AT.

Cancer Genet Cytogenet. 1999 Dec;115(2):100-5.

PMID:
10598141
21.

Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1).

Bodner SM, Naeve CW, Rakestraw KM, Jones BG, Valentine VA, Valentine MB, Luthardt FW, Willman CL, Raimondi SC, Downing JR, Roussel MF, Sherr CJ, Look AT.

Gene. 1999 Mar 18;229(1-2):223-8.

PMID:
10095122
22.

Fluorescence in situ hybridization analysis of chromosome 1p36 deletions in human MYCN amplified neuroblastoma.

Komuro H, Valentine MB, Rowe ST, Kidd VJ, Makino S, Brodeur GM, Cohn SL, Look AT.

J Pediatr Surg. 1998 Nov;33(11):1695-8.

PMID:
9856898
23.

Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome.

Nichols KE, Harkin DP, Levitz S, Krainer M, Kolquist KA, Genovese C, Bernard A, Ferguson M, Zuo L, Snyder E, Buckler AJ, Wise C, Ashley J, Lovett M, Valentine MB, Look AT, Gerald W, Housman DE, Haber DA.

Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13765-70.

24.

Extensive genomic abnormalities in childhood medulloblastoma by comparative genomic hybridization.

Reardon DA, Michalkiewicz E, Boyett JM, Sublett JE, Entrekin RE, Ragsdale ST, Valentine MB, Behm FG, Li H, Heideman RL, Kun LE, Shapiro DN, Look AT.

Cancer Res. 1997 Sep 15;57(18):4042-7.

25.

Deletion of 1p36 in childhood endodermal sinus tumors by two-color fluorescence in situ hybridization: a pediatric oncology group study.

Perlman EJ, Valentine MB, Griffin CA, Look AT.

Genes Chromosomes Cancer. 1996 May;16(1):15-20.

PMID:
9162192
26.

The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1.

Yoneda-Kato N, Look AT, Kirstein MN, Valentine MB, Raimondi SC, Cohen KJ, Carroll AJ, Morris SW.

Oncogene. 1996 Jan 18;12(2):265-75.

PMID:
8570204
27.

A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3.

White PS, Maris JM, Beltinger C, Sulman E, Marshall HN, Fujimori M, Kaufman BA, Biegel JA, Allen C, Hilliard C, Valentine MB, Look AT, Enomoto H, Sakiyama S, Brodeur GM.

Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5520-4.

28.

Frequent deletion of p16INK4a/MTS1 and p15INK4b/MTS2 in pediatric acute lymphoblastic leukemia.

Okuda T, Shurtleff SA, Valentine MB, Raimondi SC, Head DR, Behm F, Curcio-Brint AM, Liu Q, Pui CH, Sherr CJ, et al.

Blood. 1995 May 1;85(9):2321-30.

29.

Lack of correlation of N-myc gene amplification with prognosis in localized neuroblastoma: a Pediatric Oncology Group study.

Cohn SL, Look AT, Joshi VV, Holbrook T, Salwen H, Chagnovich D, Chesler L, Rowe ST, Valentine MB, Komuro H, et al.

Cancer Res. 1995 Feb 15;55(4):721-6.

30.

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma.

Morris SW, Kirstein MN, Valentine MB, Dittmer K, Shapiro DN, Look AT, Saltman DL.

Science. 1995 Jan 20;267(5196):316-7. No abstract available.

PMID:
7824924
31.

Amplification of the E2F1 transcription factor gene in the HEL erythroleukemia cell line.

Saito M, Helin K, Valentine MB, Griffith BB, Willman CL, Harlow E, Look AT.

Genomics. 1995 Jan 1;25(1):130-8.

PMID:
7774910
32.

Molecular characterization of the gene for human interleukin-1 beta converting enzyme (IL1BC).

Cerretti DP, Hollingsworth LT, Kozlosky CJ, Valentine MB, Shapiro DN, Morris SW, Nelson N.

Genomics. 1994 Apr;20(3):468-73.

PMID:
8034320
33.

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma.

Morris SW, Kirstein MN, Valentine MB, Dittmer KG, Shapiro DN, Saltman DL, Look AT.

Science. 1994 Mar 4;263(5151):1281-4. Erratum in: Science. 1995 Jan 20;267(5196):316-7.

PMID:
8122112
34.

The gene for PAX7, a member of the paired-box-containing genes, is localized on human chromosome arm 1p36.

Shapiro DN, Sublett JE, Li B, Valentine MB, Morris SW, Noll M.

Genomics. 1993 Sep;17(3):767-9.

PMID:
7902328
35.

Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras.

Johnson MR, Look AT, DeClue JE, Valentine MB, Lowy DR.

Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5539-43.

36.

Detection of N-myc gene amplification by fluorescence in situ hybridization. Diagnostic utility for neuroblastoma.

Shapiro DN, Valentine MB, Rowe ST, Sinclair AE, Sublett JE, Roberts WM, Look AT.

Am J Pathol. 1993 May;142(5):1339-46.

37.

Reassignment of the human ARH9 RAS-related gene to chromosome 1p13-p21.

Morris SW, Valentine MB, Kirstein MN, Huebner K.

Genomics. 1993 Mar;15(3):677-9.

PMID:
8468062
38.

Cell transformation by ras and regulation of its protein product.

Lowy DR, Johnson MR, DeClue JE, Cen H, Zhang K, Papageorge AG, Vass WC, Willumsen BM, Valentine MB, Look AT.

Ciba Found Symp. 1993;176:67-80; discussion 80-4. Review.

PMID:
8299427
39.

Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to chromosome 2q35.

Morris SW, Nelson N, Valentine MB, Shapiro DN, Look AT, Kozlosky CJ, Beckmann MP, Cerretti DP.

Genomics. 1992 Nov;14(3):685-91.

PMID:
1427896
40.

Sublocalization of the chromosome 5 breakpoint of the 3;5 translocation in myelodysplastic syndromes and acute myeloid leukemia.

Morris SW, Foust JT, Valentine MB, Roberts WM, Shapiro DN, Look AT.

Genes Chromosomes Cancer. 1992 Nov;5(4):385-91.

PMID:
1283327
41.

Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26.

Morishita K, Parganas E, William CL, Whittaker MH, Drabkin H, Oval J, Taetle R, Valentine MB, Ihle JN.

Proc Natl Acad Sci U S A. 1992 May 1;89(9):3937-41.

42.

Chromosomal sublocalization of the 2;13 translocation breakpoint in alveolar rhabdomyosarcoma.

Shapiro DN, Valentine MB, Sublett JE, Sinclair AE, Tereba AM, Scheffer H, Buys CH, Look AT.

Genes Chromosomes Cancer. 1992 Apr;4(3):241-9.

PMID:
1382566
43.

Chromosomal localization of human O6-methylguanine-DNA methyltransferase (MGMT) gene by in situ hybridization.

Natarajan AT, Vermeulen S, Darroudi F, Valentine MB, Brent TP, Mitra S, Tano K.

Mutagenesis. 1992 Jan;7(1):83-5.

PMID:
1635460
44.

His-1 and His-2: identification and chromosomal mapping of two commonly rearranged sites of viral integration in a myeloid leukemia.

Askew DS, Bartholomew C, Buchberg AM, Valentine MB, Jenkins NA, Copeland NG, Ihle JN.

Oncogene. 1991 Nov;6(11):2041-7.

PMID:
1682866
45.

Reassignment of the human CSF1 gene to chromosome 1p13-p21.

Morris SW, Valentine MB, Shapiro DN, Sublett JE, Deaven LL, Foust JT, Roberts WM, Cerretti DP, Look AT.

Blood. 1991 Oct 15;78(8):2013-20.

46.

The right to appoint a representative.

Valentine MB, Giuffrida D.

Can J Psychiatry. 1991 May;36(4):313-4. No abstract available.

PMID:
1868431
47.

The human Evi-1 gene is located on chromosome 3q24-q28 but is not rearranged in three cases of acute nonlymphocytic leukemias containing t(3;5)(q25;q34) translocations.

Morishita K, Parganas E, Bartholomew C, Sacchi N, Valentine MB, Raimondi SC, Le Beau MM, Ihle JN.

Oncogene Res. 1990;5(3):221-31.

PMID:
2108405
48.
49.

Mental health consumer participation on boards and committees: barriers and strategies.

Valentine MB, Capponi P.

Can Ment Health. 1989 Jun;37(2):8-12.

PMID:
10294601
50.

Political awareness of psychiatric patients.

Valentine MB, Turner T.

CMAJ. 1989 Mar 1;140(5):498. No abstract available.

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