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Items: 5


Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes.

Hess GT, Tycko J, Yao D, Bassik MC.

Mol Cell. 2017 Oct 5;68(1):26-43. doi: 10.1016/j.molcel.2017.09.029. Review.


Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.

Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, Simeonov DR, Suliman N, Li R, Xu J, Flynn RA, Kundaje A, Khavari PA, Marson A, Corn JE, Quertermous T, Greenleaf WJ, Chang HY.

Nat Genet. 2017 Nov;49(11):1602-1612. doi: 10.1038/ng.3963. Epub 2017 Sep 25.


Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity.

Tycko J, Myer VE, Hsu PD.

Mol Cell. 2016 Aug 4;63(3):355-70. doi: 10.1016/j.molcel.2016.07.004. Review.


Toolbox for Exploring Modular Gene Regulation in Synthetic Biology Training.

Magaraci MS, Bermudez JG, Yogish D, Pak DH, Mollov V, Tycko J, Issadore D, Mannickarottu SG, Chow BY.

ACS Synth Biol. 2016 Jul 15;5(7):781-5. doi: 10.1021/acssynbio.6b00057. Epub 2016 May 12.


Lessons learned from the clinical development and market authorization of Glybera.

Bryant LM, Christopher DM, Giles AR, Hinderer C, Rodriguez JL, Smith JB, Traxler EA, Tycko J, Wojno AP, Wilson JM.

Hum Gene Ther Clin Dev. 2013 Jun;24(2):55-64. doi: 10.1089/humc.2013.087. Epub 2013 Jun 29. Review. No abstract available.

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