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Impact of T2R38 Receptor Polymorphisms on Pseudomonas aeruginosa Infection in Cystic Fibrosis.

Turnbull AR, Murphy R, Behrends V, Lund-Palau H, Simbo A, Mariveles M, Alton EW, Bush A, Shoemark A, Davies JC.

Am J Respir Crit Care Med. 2018 Feb 26. doi: 10.1164/rccm.201711-2365LE. [Epub ahead of print] No abstract available.


Fate of Paralytic Shellfish Toxins in Southern Rock Lobster ( Jasus edwardsii) during Cooking: Concentration, Composition, and Distribution.

Turnbull A, Malhi N, Tan J, Harwood DT, Madigan T.

J Food Prot. 2018 Feb;81(2):240-245. doi: 10.4315/0362-028X.JFP-17-280.


Experimental uptake and depuration of paralytic shellfish toxins in Southern Rock Lobster, Jasus edwardsii.

Madigan T, Malhi N, Tan J, McLeod C, Stewart I, Harwood T, Mann G, Turnbull A.

Toxicon. 2018 Mar 1;143:44-50. doi: 10.1016/j.toxicon.2018.01.001. Epub 2018 Jan 8.


Pre-operative Endocrine Therapy.

Arthur LM, Turnbull AK, Khan LR, Dixon JM.

Curr Breast Cancer Rep. 2017;9(4):202-209. doi: 10.1007/s12609-017-0255-6. Epub 2017 Oct 27. Review.


Pooling of bronchoalveolar lavage in children with cystic fibrosis does not adversely affect the microbiological yield or sensitivity in detecting pulmonary inflammation.

McNally P, O'Rourke J, Fantino E, Chacko A, Pabary R, Turnbull A, Grant T, O'Sullivan N, Wainwright C, Linnane B, Davies JC, Sly PD.

J Cyst Fibros. 2017 Nov 17. pii: S1569-1993(17)30955-4. doi: 10.1016/j.jcf.2017.10.016. [Epub ahead of print]


Development and preliminary evidence of the psychometric properties of the GNE myopathy functional activity scale.

Mayhew J, Bonner N, Arbuckle R, Turnbull A, Bowden A, Skrinar A.

J Comp Eff Res. 2018 Apr;7(4):381-395. doi: 10.2217/cer-2017-0062. Epub 2017 Nov 15.


Patients' Outcomes After Acute Respiratory Failure: A Qualitative Study With the PROMIS Framework.

Eakin MN, Patel Y, Mendez-Tellez P, Dinglas VD, Needham DM, Turnbull AE.

Am J Crit Care. 2017 Nov;26(6):456-465. doi: 10.4037/ajcc2017834.


Molecular basis of USP7 inhibition by selective small-molecule inhibitors.

Turnbull AP, Ioannidis S, Krajewski WW, Pinto-Fernandez A, Heride C, Martin ACL, Tonkin LM, Townsend EC, Buker SM, Lancia DR, Caravella JA, Toms AV, Charlton TM, Lahdenranta J, Wilker E, Follows BC, Evans NJ, Stead L, Alli C, Zarayskiy VV, Talbot AC, Buckmelter AJ, Wang M, McKinnon CL, Saab F, McGouran JF, Century H, Gersch M, Pittman MS, Marshall CG, Raynham TM, Simcox M, Stewart LMD, McLoughlin SB, Escobedo JA, Bair KW, Dinsmore CJ, Hammonds TR, Kim S, Urbé S, Clague MJ, Kessler BM, Komander D.

Nature. 2017 Oct 26;550(7677):481-486. doi: 10.1038/nature24451. Epub 2017 Oct 18.


A brief intervention for preparing ICU families to be proxies: A phase I study.

Turnbull AE, Chessare CM, Coffin RK, Needham DM.

PLoS One. 2017 Oct 2;12(10):e0185483. doi: 10.1371/journal.pone.0185483. eCollection 2017.


What is the future of Public Health Policy within the European Union?

Azzopardi-Muscat N, Czabanowska K, Tamsma N, Turnbull A.

Eur J Public Health. 2017 Oct 1;27(5):792-793. doi: 10.1093/eurpub/ckx115. No abstract available.


A High-Throughput Screening Triage Workflow to Authenticate a Novel Series of PFKFB3 Inhibitors.

St-Gallay SA, Bennett N, Critchlow SE, Curtis N, Davies G, Debreczeni J, Evans N, Hardern I, Holdgate G, Jones NP, Leach L, Maman S, McLoughlin S, Preston M, Rigoreau L, Thomas A, Turnbull AP, Walker G, Walsh J, Ward RA, Wheatley E, Winter-Holt J.

SLAS Discov. 2018 Jan;23(1):11-22. doi: 10.1177/2472555217732289. Epub 2017 Sep 25.


National survey of foodborne viruses in Australian oysters at production.

Torok V, Hodgson K, McLeod C, Tan J, Malhi N, Turnbull A.

Food Microbiol. 2018 Feb;69:196-203. doi: 10.1016/ Epub 2017 Aug 22.


Margin width and local recurrence after breast conserving surgery for ductal carcinoma in situ.

Ekatah GE, Turnbull AK, Arthur LM, Thomas J, Dodds C, Dixon JM.

Eur J Surg Oncol. 2017 Nov;43(11):2029-2035. doi: 10.1016/j.ejso.2017.08.003. Epub 2017 Sep 4.


Current and future therapies for Pseudomonas aeruginosa infection in patients with cystic fibrosis.

Smith WD, Bardin E, Cameron L, Edmondson CL, Farrant KV, Martin I, Murphy RA, Soren O, Turnbull AR, Wierre-Gore N, Alton EW, Bundy JG, Bush A, Connett GJ, Faust SN, Filloux A, Freemont PS, Jones AL, Takats Z, Webb JS, Williams HD, Davies JC.

FEMS Microbiol Lett. 2017 Aug 1;364(14). doi: 10.1093/femsle/fnx121. Review.


Detection of Paralytic Shellfish Toxins in Mussels and Oysters Using the Qualitative Neogen Lateral-Flow Immunoassay: An Interlaboratory Study.

Dorantes-Aranda JJ, Tan JYC, Hallegraeff GM, Campbell K, Ugalde SC, Harwood DT, Bartlett JK, Campàs M, Crooks S, Gerssen A, Harrison K, Huet AC, Jordan TB, Koeberl M, Monaghan T, Murray S, Nimmagadda R, Ooms C, Quinlan RK, Shi F, Turner AD, Yakes BJ, Turnbull AR.

J AOAC Int. 2018 Mar 1;101(2):468-479. doi: 10.5740/jaoacint.17-0221. Epub 2017 Aug 30.


Single-Laboratory Validation of the Neogen Qualitative Lateral Flow Immunoassay for the Detection of Paralytic Shellfish Toxins in Mussels and Oysters.

Turnbull AR, Tan JYC, Ugalde SC, Hallegraeff GM, Campbell K, Harwood DT, Dorantes-Aranda JJ.

J AOAC Int. 2018 Mar 1;101(2):480-489. doi: 10.5740/jaoacint.17-0135. Epub 2017 Aug 10.


Perspectives of survivors, families and researchers on key outcomes for research in acute respiratory failure.

Dinglas VD, Chessare CM, Davis WE, Parker A, Friedman LA, Colantuoni E, Bingham CO, Turnbull AE, Needham DM.

Thorax. 2018 Jan;73(1):7-12. doi: 10.1136/thoraxjnl-2017-210234. Epub 2017 Jul 29.


A Case of Pulmonary Mucormycosis in a Renal Transplant Recipient.

Turnbull A, Chembo CL, Leikis M, Pidgeon G, Arnold L, Hay N, Matheson P.

Nephrology (Carlton). 2017 Aug;22(8):657. doi: 10.1111/nep.12855. No abstract available.


Goal-concordant care in the ICU: a conceptual framework for future research.

Turnbull AE, Hartog CS.

Intensive Care Med. 2017 Dec;43(12):1847-1849. doi: 10.1007/s00134-017-4873-2. Epub 2017 Jun 27. No abstract available.


Individual differences in functional connectivity during naturalistic viewing conditions.

Vanderwal T, Eilbott J, Finn ES, Craddock RC, Turnbull A, Castellanos FX.

Neuroimage. 2017 Aug 15;157:521-530. doi: 10.1016/j.neuroimage.2017.06.027. Epub 2017 Jun 16.


Nitric oxide induces human CLA+CD25+Foxp3+ regulatory T cells with skin-homing potential.

Yu C, Fitzpatrick A, Cong D, Yao C, Yoo J, Turnbull A, Schwarze J, Norval M, Howie SEM, Weller RB, Astier AL.

J Allergy Clin Immunol. 2017 Nov;140(5):1441-1444.e6. doi: 10.1016/j.jaci.2017.05.023. Epub 2017 Jun 7. No abstract available.


Translational Modeling to Guide Study Design and Dose Choice in Obesity Exemplified by AZD1979, a Melanin-concentrating Hormone Receptor 1 Antagonist.

Gennemark P, Trägårdh M, Lindén D, Ploj K, Johansson A, Turnbull A, Carlsson B, Antonsson M.

CPT Pharmacometrics Syst Pharmacol. 2017 Jul;6(7):458-468. doi: 10.1002/psp4.12199. Epub 2017 May 27.


Evaluation of a strategy for enrolling the families of critically ill patients in research using limited human resources.

Turnbull AE, Hashem MD, Rabiee A, To A, Chessare CM, Needham DM.

PLoS One. 2017 May 25;12(5):e0177741. doi: 10.1371/journal.pone.0177741. eCollection 2017.


Core Outcome Measures for Clinical Research in Acute Respiratory Failure Survivors. An International Modified Delphi Consensus Study.

Needham DM, Sepulveda KA, Dinglas VD, Chessare CM, Friedman LA, Bingham CO 3rd, Turnbull AE.

Am J Respir Crit Care Med. 2017 Nov 1;196(9):1122-1130. doi: 10.1164/rccm.201702-0372OC.


Effect of second timed appointments for non-attenders of breast cancer screening in England: a randomised controlled trial.

Allgood PC, Maroni R, Hudson S, Offman J, Turnbull AE, Peacock L, Steel J, Kirby G, Ingram CE, Somers J, Fuller C, Threlfall AG, Gabe R, Maxwell AJ, Patnick J, Duffy SW.

Lancet Oncol. 2017 Jul;18(7):972-980. doi: 10.1016/S1470-2045(17)30340-6. Epub 2017 May 15.


Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells.

Meehan J, Ward C, Turnbull A, Bukowski-Wills J, Finch AJ, Jarman EJ, Xintaropoulou C, Martinez-Perez C, Gray M, Pearson M, Mullen P, Supuran CT, Carta F, Harrison DJ, Kunkler IH, Langdon SP.

Oncotarget. 2017 Jun 27;8(26):42857-42875. doi: 10.18632/oncotarget.17143.


Psychometric validation of the dysmenorrhea daily diary (DysDD): a patient-reported outcome for dysmenorrhea.

Nguyen AM, Arbuckle R, Korver T, Chen F, Taylor B, Turnbull A, Norquist JM.

Qual Life Res. 2017 Aug;26(8):2041-2055. doi: 10.1007/s11136-017-1562-0. Epub 2017 Apr 12.


Current treatment trends and the need for better predictive tools in the management of ductal carcinoma in situ of the breast.

Martínez-Pérez C, Turnbull AK, Ekatah GE, Arthur LM, Sims AH, Thomas JS, Dixon JM.

Cancer Treat Rev. 2017 Apr;55:163-172. doi: 10.1016/j.ctrv.2017.03.009. Epub 2017 Mar 31. Review.


Bacteriophages as enteric viral indicators in bivalve mollusc management.

Hodgson KR, Torok VA, Turnbull AR.

Food Microbiol. 2017 Aug;65:284-293. doi: 10.1016/ Epub 2017 Mar 6. Review.


Core Domains for Clinical Research in Acute Respiratory Failure Survivors: An International Modified Delphi Consensus Study.

Turnbull AE, Sepulveda KA, Dinglas VD, Chessare CM, Bingham CO 3rd, Needham DM.

Crit Care Med. 2017 Jun;45(6):1001-1010. doi: 10.1097/CCM.0000000000002435.


Confirmatory Factor Analysis of a Family Quality of Life Scale for Taiwanese Families of Children With Intellectual Disability/Developmental Delay.

Chiu CY, Seo H, Turnbull AP, Summers JA.

Intellect Dev Disabil. 2017 Apr;55(2):57-71. doi: 10.1352/1934-9556-55.2.57.


Core Domains in Evaluating Patient Outcomes After Acute Respiratory Failure: International Multidisciplinary Clinician Consultation.

Hodgson CL, Turnbull AE, Iwashyna TJ, Parker A, Davis W, Bingham CO, Watts NR, Finfer S, Needham DM.

Phys Ther. 2017 Feb 1;97(2):168-174. doi: 10.2522/ptj.20160196. No abstract available.


Transconjunctival intrascleral intraocular lens fixation with double-needle and flanged-haptic technique: Ultrathin line between success and failure.

Turnbull AM, Lash SC.

J Cataract Refract Surg. 2016 Dec;42(12):1843-1844. doi: 10.1016/j.jcrs.2016.11.001. No abstract available.


A PAM50-Based Chemoendocrine Score for Hormone Receptor-Positive Breast Cancer with an Intermediate Risk of Relapse.

Prat A, Lluch A, Turnbull AK, Dunbier AK, Calvo L, Albanell J, de la Haba-Rodríguez J, Arcusa A, Chacón JI, Sánchez-Rovira P, Plazaola A, Muñoz M, Paré L, Parker JS, Ribelles N, Jimenez B, Bin Aiderus AA, Caballero R, Adamo B, Dowsett M, Carrasco E, Martín M, Dixon JM, Perou CM, Alba E.

Clin Cancer Res. 2017 Jun 15;23(12):3035-3044. doi: 10.1158/1078-0432.CCR-16-2092. Epub 2016 Nov 30.


A systematic review finds limited data on measurement properties of instruments measuring outcomes in adult intensive care unit survivors.

Robinson KA, Davis WE, Dinglas VD, Mendez-Tellez PA, Rabiee A, Sukrithan V, Yalamanchilli R, Turnbull AE, Needham DM.

J Clin Epidemiol. 2017 Feb;82:37-46. doi: 10.1016/j.jclinepi.2016.08.014. Epub 2016 Nov 16. Review.


Response to: Comments on 'Confidence of ophthalmology trainees in the management of posterior capsule rupture and vitreous loss'.

Turnbull AM, Lash SC.

Eye (Lond). 2017 Apr;31(4):661-662. doi: 10.1038/eye.2016.223. Epub 2016 Nov 11. No abstract available.


Anxiety symptoms in survivors of critical illness: a systematic review and meta-analysis.

Nikayin S, Rabiee A, Hashem MD, Huang M, Bienvenu OJ, Turnbull AE, Needham DM.

Gen Hosp Psychiatry. 2016 Nov - Dec;43:23-29. doi: 10.1016/j.genhosppsych.2016.08.005. Epub 2016 Aug 28. Review.


Discovery of potent inhibitors of the lysophospholipase autotaxin.

Shah P, Cheasty A, Foxton C, Raynham T, Farooq M, Gutierrez IF, Lejeune A, Pritchard M, Turnbull A, Pang L, Owen P, Boyd S, Stowell A, Jordan A, Hamilton NM, Hitchin JR, Stockley M, MacDonald E, Quesada MJ, Trivier E, Skeete J, Ovaa H, Moolenaar WH, Ryder H.

Bioorg Med Chem Lett. 2016 Nov 15;26(22):5403-5410. doi: 10.1016/j.bmcl.2016.10.036. Epub 2016 Oct 14.


Aligning critical care interventions with patient goals: A modified Delphi study.

Turnbull AE, Sahetya SK, Needham DM.

Heart Lung. 2016 Nov - Dec;45(6):517-524. doi: 10.1016/j.hrtlng.2016.07.011. Epub 2016 Sep 1.


Cefepime Therapy for Cefepime-Susceptible Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Bacteremia.

Wang R, Cosgrove SE, Tschudin-Sutter S, Han JH, Turnbull AE, Hsu AJ, Avdic E, Carroll KC, Tamma PD.

Open Forum Infect Dis. 2016 Jun 20;3(3):ofw132. doi: 10.1093/ofid/ofw132. eCollection 2016 Sep.


Effects of a novel potent melanin-concentrating hormone receptor 1 antagonist, AZD1979, on body weight homeostasis in mice and dogs.

Ploj K, Benthem L, Kakol-Palm D, Gennemark P, Andersson L, Bjursell M, Börjesson J, Kärrberg L, Månsson M, Antonsson M, Johansson A, Iverson S, Carlsson B, Turnbull A, Lindén D.

Br J Pharmacol. 2016 Sep;173(18):2739-51. doi: 10.1111/bph.13548. Epub 2016 Aug 3.


Tumour sampling method can significantly influence gene expression profiles derived from neoadjuvant window studies.

Pearce DA, Arthur LM, Turnbull AK, Renshaw L, Sabine VS, Thomas JS, Bartlett JM, Dixon JM, Sims AH.

Sci Rep. 2016 Jul 7;6:29434. doi: 10.1038/srep29434.


Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.

Sachdev V, Leopold C, Bauer R, Patankar JV, Iqbal J, Obrowsky S, Boverhof R, Doktorova M, Scheicher B, Goeritzer M, Kolb D, Turnbull AV, Zimmer A, Hoefler G, Hussain MM, Groen AK, Kratky D.

Biochim Biophys Acta. 2016 Sep;1861(9 Pt A):1132-1141. doi: 10.1016/j.bbalip.2016.06.014. Epub 2016 Jun 23.


Novel histopathologic feature identified through image analysis augments stage II colorectal cancer clinical reporting.

Caie PD, Zhou Y, Turnbull AK, Oniscu A, Harrison DJ.

Oncotarget. 2016 Jul 12;7(28):44381-44394. doi: 10.18632/oncotarget.10053.


Intensivist-reported Facilitators and Barriers to Discussing Post-Discharge Outcomes with Intensive Care Unit Surrogates. A Qualitative Study.

Turnbull AE, Davis WE, Needham DM, White DB, Eakin MN.

Ann Am Thorac Soc. 2016 Sep;13(9):1546-52. doi: 10.1513/AnnalsATS.201603-212OC.


Pseudomonas aeruginosa infection in cystic fibrosis: pathophysiological mechanisms and therapeutic approaches.

Lund-Palau H, Turnbull AR, Bush A, Bardin E, Cameron L, Soren O, Wierre-Gore N, Alton EW, Bundy JG, Connett G, Faust SN, Filloux A, Freemont P, Jones A, Khoo V, Morales S, Murphy R, Pabary R, Simbo A, Schelenz S, Takats Z, Webb J, Williams HD, Davies JC.

Expert Rev Respir Med. 2016 Jun;10(6):685-97. doi: 10.1080/17476348.2016.1177460. Epub 2016 May 13. Review.


Depressive Symptoms After Critical Illness: A Systematic Review and Meta-Analysis.

Rabiee A, Nikayin S, Hashem MD, Huang M, Dinglas VD, Bienvenu OJ, Turnbull AE, Needham DM.

Crit Care Med. 2016 Sep;44(9):1744-53. doi: 10.1097/CCM.0000000000001811. Review.


Confidence of ophthalmology specialist trainees in the management of posterior capsule rupture and vitreous loss.

Turnbull AM, Lash SC.

Eye (Lond). 2016 Jul;30(7):943-8. doi: 10.1038/eye.2016.55. Epub 2016 Apr 15.


Antitumour activity of the novel flavonoid Oncamex in preclinical breast cancer models.

Martínez-Pérez C, Ward C, Turnbull AK, Mullen P, Cook G, Meehan J, Jarman EJ, Thomson PI, Campbell CJ, McPhail D, Harrison DJ, Langdon SP.

Br J Cancer. 2016 Apr 12;114(8):905-16. doi: 10.1038/bjc.2016.6. Epub 2016 Mar 31.


New drug developments in the management of cystic fibrosis lung disease.

Turnbull AR, Davies JC.

Expert Opin Pharmacother. 2016 Jun;17(8):1103-12. doi: 10.1517/14656566.2016.1157582. Epub 2016 Mar 28. Review.


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