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Design, Synthesis and Biological Activity of New N-(Phenylmethyl)-benzoxazol-2-thiones as Macrophage Migration Inhibitory Factor (MIF) Antagonists: Efficacies in Experimental Pulmonary Hypertension.

Le Hiress M, Akagah B, Bernadat G, Tu L, Thuillet R, Huertas A, Phan C, Fadel E, Simonneau G, Humbert M, Jalce G, Guignabert C.

J Med Chem. 2018 Mar 10. doi: 10.1021/acs.jmedchem.7b01312. [Epub ahead of print]



Malhotra A, Wu X, Tu LH, Seifert K.

Spine (Phila Pa 1976). 2018 Mar 15;43(6):E379-E380. doi: 10.1097/BRS.0000000000002544. No abstract available.


Near Infrared Light Sensitive Ultraviolet-Blue Nanophotoswitch for Imaging-Guided "Off-On" Therapy.

Zuo J, Tu L, Li Q, Feng Y, Que I, Zhang Y, Liu X, Xue B, Cruz LJ, Chang Y, Zhang H, Kong X.

ACS Nano. 2018 Mar 2. doi: 10.1021/acsnano.7b07393. [Epub ahead of print]


Management of blunt cerebrovascular injury (BCVI) in the multisystem injury patient with contraindications to immediate anti-thrombotic therapy.

Malhotra A, Wu X, Tu L, Seifert K.

Injury. 2018 Feb 2. pii: S0020-1383(18)30019-6. doi: 10.1016/j.injury.2018.01.018. [Epub ahead of print] No abstract available.


Aberrantly expressed long noncoding RNAs in hypertrophic scar fibroblasts in vitro: A microarray study.

Tu L, Huang Q, Fu S, Liu D.

Int J Mol Med. 2018 Apr;41(4):1917-1930. doi: 10.3892/ijmm.2018.3430. Epub 2018 Jan 26.


Blunt Cerebrovascular Artery Injury and Stroke in Severely Injured Patients: An International Multicenter Analysis.

Malhotra A, Wu X, Seifert K, Tu L.

World J Surg. 2018 Jan 30. doi: 10.1007/s00268-018-4518-9. [Epub ahead of print] No abstract available.


Evolutionary dynamics of 3D genome architecture following polyploidization in cotton.

Wang M, Wang P, Lin M, Ye Z, Li G, Tu L, Shen C, Li J, Yang Q, Zhang X.

Nat Plants. 2018 Feb;4(2):90-97. doi: 10.1038/s41477-017-0096-3. Epub 2018 Jan 29.


Letter to the Editor Regarding "Increased detection of blunt carotid and vertebral artery injury after implementation of diagnostic imaging pathway in level 1 trauma centre in Western Australia".

Malhotra A, Wu X, Tu L, Seifert K.

Injury. 2018 Jan 20. pii: S0020-1383(18)30014-7. doi: 10.1016/j.injury.2018.01.013. [Epub ahead of print] No abstract available.


Precisely Tailoring Upconversion Dynamics via Energy Migration in Core-Shell Nanostructures.

Zuo J, Sun D, Tu L, Wu Y, Cao Y, Xue B, Zhang Y, Chang Y, Liu X, Kong X, Buma WJ, Meijer EJ, Zhang H.

Angew Chem Int Ed Engl. 2018 Mar 12;57(12):3054-3058. doi: 10.1002/anie.201711606. Epub 2018 Feb 14.


Dasatinib increases endothelial permeability leading to pleural effusion.

Phan C, Jutant EM, Tu L, Thuillet R, Seferian A, Montani D, Huertas A, Bezu JV, Breijer F, Vonk Noordegraaf A, Humbert M, Aman J, Guignabert C.

Eur Respir J. 2018 Jan 18;51(1). pii: 1701096. doi: 10.1183/13993003.01096-2017. Print 2018 Jan.


Intracisternal tuberculoma: a refractory type of tuberculoma indicating surgical intervention.

Chen F, Chen L, Cao Y, Yi Y, Zhuang J, Le W, Xie W, Tu L, Li P, Fang Y, Li L, Kou Y, Fu K, He H, Ju H.

BMC Neurol. 2018 Jan 18;18(1):10. doi: 10.1186/s12883-017-0996-x.


AZD9291 Increases Sensitivity to Radiation in PC-9-IR Cells by Delaying DNA Damage Repair after Irradiation and Inducing Apoptosis.

Wu S, Zhu L, Tu L, Chen S, Huang H, Zhang J, Ma S, Zhang S.

Radiat Res. 2018 Mar;189(3):283-291. doi: 10.1667/RR14682.1. Epub 2018 Jan 13.


Endothelium-specific CYP2J2 overexpression attenuates age-related insulin resistance.

Yang Y, Dong R, Chen Z, Hu D, Fu M, Tang Y, Wang DW, Xu X, Tu L.

Aging Cell. 2018 Apr;17(2). doi: 10.1111/acel.12718. Epub 2018 Jan 10.


AAV-mediated gene delivery of the calreticulin anti-angiogenic domain inhibits ocular neovascularization.

Tu L, Wang JH, Barathi VA, Prea SM, He Z, Lee JH, Bender J, King AE, Logan GJ, Alexander IE, Bee YS, Tai MH, Dusting GJ, Bui BV, Zhong J, Liu GS.

Angiogenesis. 2018 Feb;21(1):95-109. doi: 10.1007/s10456-017-9591-4. Epub 2018 Jan 9.


Letter to the Editor Regarding "Indications for CT-Angiography of the Vertebral Arteries after Trauma".

Malhotra A, Wu X, Tu LH, Seifert K.

Spine (Phila Pa 1976). 2018 Jan 5. doi: 10.1097/BRS.0000000000002544. [Epub ahead of print] No abstract available.


Re: "Effect of Template Reporting of Brain MRIs for Multiple Sclerosis on Report Thoroughness and Neurologist-Rated Quality: Results of a Prospective Quality Improvement Project".

Malhotra A, Wu X, Tu L, Seifert K.

J Am Coll Radiol. 2018 Jan;15(1 Pt A):9. doi: 10.1016/j.jacr.2017.10.021. No abstract available.


[Changes of platelet rheological behavior and the interventional effects of ulinastatin in rats with high-voltage electrical burns].

Zhang QF, Li Y, Feng JK, Xu YF, Tu LL.

Zhonghua Shao Shang Za Zhi. 2017 Dec 20;33(12):744-749. doi: 10.3760/cma.j.issn.1009-2587.2017.12.005. Chinese.


Letter to the Editor regarding "Comparison of Rates of Growth between Unruptured and Ruptured Aneurysms Using Magnetic Resonance Angiography".

Malhotra A, Wu X, Tu LH, Seifert K.

J Stroke Cerebrovasc Dis. 2018 Mar;27(3):821. doi: 10.1016/j.jstrokecerebrovasdis.2017.11.020. Epub 2017 Dec 19. No abstract available.


[Sesquiterpenes with anti-metastasis breast cancer activity from Chloranthus henryi].

Zhang SS, Fu JJ, Chen HY, Tu LF, Xiao CR, Zhang RZ, Liu DP, Luo YM.

Zhongguo Zhong Yao Za Zhi. 2017 Oct;42(20):3938-3944. doi: 10.19540/j.cnki.cjcmm.2017.0159. Chinese.


[Analysis of Forensic Identification on 32 Cases of Lumbar Spondylolysis].

Tu LF, Chen YP, Zhang SP.

Fa Yi Xue Za Zhi. 2017 Jun;33(3):258-262. doi: 10.3969/j.issn.1004-5619.2017.03.009. Epub 2017 Jun 25. Chinese.


Evaluation of protective efficacy of three novel H3N2 canine influenza vaccines.

Tu L, Zhou P, Li L, Li X, Hu R, Jia K, Sun L, Yuan Z, Li S.

Oncotarget. 2017 Sep 20;8(58):98084-98093. doi: 10.18632/oncotarget.21104. eCollection 2017 Nov 17.


Prevalence of comorbidities and evaluation of screening in Chinese patients with spondyloarthritis.

Jiang Y, Zhang P, Tu L, Lv Q, Qi J, Lin Z, Liao Z, Cao S, Gu J.

Clin Rheumatol. 2018 Feb;37(2):423-428. doi: 10.1007/s10067-017-3905-1. Epub 2017 Dec 4.


The inhibitory effect of Aconiti Sinomontani Radix extracts on the proliferation and migration of human synovial fibroblast cell line SW982.

Deng X, Zheng LP, Mu ZQ, Lai R, Niu GP, Tu LP, Zhu D, Liu YQ.

J Ethnopharmacol. 2018 Mar 1;213:321-327. doi: 10.1016/j.jep.2017.11.029. Epub 2017 Nov 28.


cfa-miR-143 Promotes Apoptosis via the p53 Pathway in Canine Influenza Virus H3N2-Infected Cells.

Zhou P, Tu L, Lin X, Hao X, Zheng Q, Zeng W, Zhang X, Zheng Y, Wang L, Li S.

Viruses. 2017 Nov 25;9(12). pii: E360. doi: 10.3390/v9120360.


Notoginsenoside R1 Alleviates Oxygen-Glucose Deprivation/Reoxygenation Injury by Suppressing Endoplasmic Reticulum Calcium Release via PLC.

Wang Y, Tu L, Li Y, Chen D, Liu Z, Hu X, Wang S.

Sci Rep. 2017 Nov 24;7(1):16226. doi: 10.1038/s41598-017-16373-7.


Intracranial Volume Quantification from 3D Photography.

Tu L, Porras AR, Ensel S, Tsering D, Paniagua B, Enquobahrie A, Oh A, Keating R, Rogers GF, Linguraru MG.

Comput Assist Robot Endosc Clin Image Based Proced (2017). 2017;10550:116-123. doi: 10.1007/978-3-319-67543-5_11. Epub 2017 Sep 8.


Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.

da Silva Gonçalves Bós D, Van Der Bruggen CEE, Kurakula K, Sun XQ, Casali KR, Casali AG, Rol N, Szulcek R, Dos Remedios C, Guignabert C, Tu L, Dorfmüller P, Humbert M, Wijnker PJM, Kuster DWD, van der Velden J, Goumans MJ, Bogaard HJ, Vonk-Noordegraaf A, de Man FS, Handoko ML.

Circulation. 2018 Feb 27;137(9):910-924. doi: 10.1161/CIRCULATIONAHA.117.027451. Epub 2017 Nov 22.


A Subnano-g Electrostatic Force-Rebalanced Flexure Accelerometer for Gravity Gradient Instruments.

Yan S, Xie Y, Zhang M, Deng Z, Tu L.

Sensors (Basel). 2017 Nov 18;17(11). pii: E2669. doi: 10.3390/s17112669.


Prevalence of Jones Fracture Repair and Impact on Short-Term NFL Participation.

Tu LA, Knapik DM, Sheehan J, Salata MJ, Voos JE.

Foot Ankle Int. 2018 Jan;39(1):6-10. doi: 10.1177/1071100717733990. Epub 2017 Nov 20.


ITGBL1 Predicts a Poor Prognosis and Correlates EMT Phenotype in Gastric Cancer.

Li R, Zhuang C, Jiang S, Du N, Zhao W, Tu L, Cao H, Zhang Z, Chen X.

J Cancer. 2017 Oct 17;8(18):3764-3773. doi: 10.7150/jca.20900. eCollection 2017.


Long noncoding RNAs involve in resistance to Verticillium dahliae, a fungal disease in cotton.

Zhang L, Wang M, Li N, Wang H, Qiu P, Pei L, Xu Z, Wang T, Gao E, Liu J, Liu S, Hu Q, Miao Y, Lindsey K, Tu L, Zhu L, Zhang X.

Plant Biotechnol J. 2017 Nov 17. doi: 10.1111/pbi.12861. [Epub ahead of print]


Effects and safety of 99Tc-MDP in patients with refractory ankylosing spondylitis: a 2-stage (30-week follow-up) clinical trial.

Xu Y, Zhong Y, Zhao M, Tu L, Fan M, Zhang P, Wei Q, Cao S, Li Q, Liao Z, Lin Z, Pan Y, Jin O, Gu J.

Clin Exp Rheumatol. 2017 Nov 14. [Epub ahead of print]


WBSCR22 confers oxaliplatin resistance in human colorectal cancer.

Yan D, Tu L, Yuan H, Fang J, Cheng L, Zheng X, Wang X.

Sci Rep. 2017 Nov 13;7(1):15443. doi: 10.1038/s41598-017-15749-z.


Incidence and risk factors for infection in spine surgery: A prospective multicenter study of 1764 instrumented spinal procedures.

Gu W, Tu L, Liang Z, Wang Z, Aikenmu K, Chu G, Zhang E, Zhao J.

Am J Infect Control. 2018 Jan;46(1):8-13. doi: 10.1016/j.ajic.2017.09.025. Epub 2017 Nov 9.


A metabolic exposure-oriented network regulation strategy for the identification of effective combination in the extract of Ginkgo biloba L.

Liu XG, Cheng CY, Wang JX, Luo H, Tu LF, Lin L, Wu B, Wang HY, Liu K, Li P, Yang H.

J Pharm Biomed Anal. 2018 Feb 5;149:151-159. doi: 10.1016/j.jpba.2017.11.004. Epub 2017 Nov 6.


Generation of human-induced pluripotent stem cells from burn patient-derived skin fibroblasts using a non-integrative method.

Fu S, Ding J, Liu D, Huang H, Li M, Liu Y, Tu L, Liu D.

Int J Mol Med. 2018 Jan;41(1):87-94. doi: 10.3892/ijmm.2017.3206. Epub 2017 Oct 23.


A genome-wide association analysis identifies PDE1A|DNAJC10 locus on chromosome 2 associated with idiopathic pulmonary arterial hypertension in a Japanese population.

Kimura M, Tamura Y, Guignabert C, Takei M, Kosaki K, Tanabe N, Tatsumi K, Saji T, Satoh T, Kataoka M, Kamitsuji S, Kamatani N, Thuillet R, Tu L, Humbert M, Fukuda K, Sano M.

Oncotarget. 2017 Aug 24;8(43):74917-74926. doi: 10.18632/oncotarget.20459. eCollection 2017 Sep 26.


Notch1 suppresses prostate cancer cell invasion via the metastasis-associated 1-KiSS-1 metastasis-suppressor pathway.

Deng G, Zheng X, Jiang P, Chen K, Wang X, Jiang K, Zhang W, Tu L, Yan D, Ma L, Ma S.

Oncol Lett. 2017 Oct;14(4):4477-4482. doi: 10.3892/ol.2017.6761. Epub 2017 Aug 17.


Probing the Single Key Amino Acid Responsible for the Novel Catalytic Function of ent-Kaurene Oxidase Supported by NADPH-Cytochrome P450 Reductases in Tripterygium wilfordii.

Su P, Guan H, Zhang Y, Wang X, Gao L, Zhao Y, Hu T, Zhou J, Ma B, Tu L, Tong Y, Huang L, Gao W.

Front Plant Sci. 2017 Oct 13;8:1756. doi: 10.3389/fpls.2017.01756. eCollection 2017.


A New Scale Factor Adjustment Method for Magnetic Force Feedback Accelerometer.

Huang X, Deng Z, Xie Y, Li Z, Fan J, Tu L.

Sensors (Basel). 2017 Oct 27;17(11). pii: E2471. doi: 10.3390/s17112471.


A Free Energy Barrier Caused by the Refolding of an Oligomeric Intermediate Controls the Lag Time of Amyloid Formation by hIAPP.

Serrano AL, Lomont JP, Tu LH, Raleigh DP, Zanni MT.

J Am Chem Soc. 2017 Nov 22;139(46):16748-16758. doi: 10.1021/jacs.7b08830. Epub 2017 Nov 7.


Melatonin Affects the Growth and Cadmium Accumulation of Malachium aquaticum and Galinsoga parviflora.

Tang Y, Lin L, Xie Y, Liu J, Sun G, Li H, Liao M, Wang Z, Liang D, Xia H, Wang X, Zhang J, Liu Z, Huang Z, He Z, Tu L.

Int J Phytoremediation. 2017 Oct 20:0. doi: 10.1080/15226514.2017.1374341. [Epub ahead of print]


Letter to the Editor Regarding "Growth of Untreated Unruptured Small-sized Aneurysms (<7 mm): Incidence and Related Factors".

Malhotra A, Wu X, Tu L, Seifert K.

Clin Neuroradiol. 2017 Oct 20. doi: 10.1007/s00062-017-0638-0. [Epub ahead of print] No abstract available.


Growth and characterization of textured well-faceted ZnO on planar Si(100), planar Si(111), and textured Si(100) substrates for solar cell applications.

Tsai CY, Lai JD, Feng SW, Huang CJ, Chen CH, Yang FW, Wang HC, Tu LW.

Beilstein J Nanotechnol. 2017 Sep 15;8:1939-1945. doi: 10.3762/bjnano.8.194. eCollection 2017.


Interaction between calcium and potassium modulates elongation rate in cotton fiber cells.

Guo K, Tu L, He Y, Deng J, Wang M, Huang H, Li Z, Zhang X.

J Exp Bot. 2017 Nov 2;68(18):5161-5175. doi: 10.1093/jxb/erx346.


Renal Denervation Reduces Pulmonary Vascular Remodeling and Right Ventricular Diastolic Stiffness in Experimental Pulmonary Hypertension.

da Silva Gonçalves Bos D, Happé C, Schalij I, Pijacka W, Paton JFR, Guignabert C, Tu L, Thuillet R, Bogaard HJ, van Rossum AC, Vonk-Noordegraaf A, de Man FS, Handoko ML.

JACC Basic Transl Sci. 2017 Feb 1;2(1):22-35. doi: 10.1016/j.jacbts.2016.09.007. eCollection 2017 Feb.


No Clinical Benefit of Empirical Antimicrobial Therapy for Pediatric Diarrhea in a High-Usage, High-Resistance Setting.

Duong VT, Tuyen HT, Van Minh P, Campbell JI, Phuc HL, Nhu TDH, Tu LTP, Chau TTH, Nhi LTQ, Hung NT, Ngoc NM, Huong NTT, Vi LL, Thompson CN, Thwaites GE, de Alwis R, Baker S.

Clin Infect Dis. 2018 Feb 1;66(4):504-511. doi: 10.1093/cid/cix844.


Effectiveness of certified diabetes educators following pre-approved protocols to redesign diabetes care delivery in primary care: Results of the REMEDIES 4D trial.

Zgibor JC, Maloney MA, Malmi M Jr, Fabio A, Kuo S, Solano FX, Tilves D, Tu L, Davidson MB.

Contemp Clin Trials. 2018 Jan;64:201-209. doi: 10.1016/j.cct.2017.10.003. Epub 2017 Oct 6.


Targeting mTORC2 component rictor inhibits cell proliferation and promotes apoptosis in gastric cancer.

Bian YH, Xu J, Zhao WY, Zhang ZZ, Tu L, Cao H, Zhang ZG.

Am J Transl Res. 2017 Sep 15;9(9):4317-4330. eCollection 2017.


Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers.

Young LM, Tu LH, Raleigh DP, Ashcroft AE, Radford SE.

Chem Sci. 2017 Jul 1;8(7):5030-5040. doi: 10.1039/c7sc00620a. Epub 2017 May 9.

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