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Liposome-Encapsulated Baicalein Suppressed Lipogenesis and Extracellular Matrix Formation in Hs68 Human Dermal Fibroblasts.

Fang CL, Wang Y, Tsai KH, Chang HI.

Front Pharmacol. 2018 Mar 6;9:155. doi: 10.3389/fphar.2018.00155. eCollection 2018.

Free Article

Fracture liaison services improve outcomes of patients with osteoporosis-related fractures: A systematic literature review and meta-analysis.

Wu CH, Tu ST, Chang YF, Chan DC, Chien JT, Lin CH, Singh S, Dasari M, Chen JF, Tsai KS.

Bone. 2018 Mar 16. pii: S8756-3282(18)30137-6. doi: 10.1016/j.bone.2018.03.018. [Epub ahead of print]


Lyssavirus in Japanese Pipistrelle, Taiwan.

Hu SC, Hsu CL, Lee MS, Tu YC, Chang JC, Wu CH, Lee SH, Ting LJ, Tsai KR, Cheng MC, Tu WJ, Hsu WC.

Emerg Infect Dis. 2018 Apr;24(4):782-785. doi: 10.3201/eid2404.171696.


Ambient air particulates-bound metallic elements sources identifications during winter and summer at a Science Park.

Fang GC, Huang CY, Zhuang YJ, Huang WC, Tsai KH, Xiao YF.

Environ Geochem Health. 2018 Mar 16. doi: 10.1007/s10653-018-0088-x. [Epub ahead of print]


Is Partial or Total Thyroidectomy Associated with Risk of Long-Term Osteoporosis: A Nationwide Population-Based Study.

Hung CL, Yeh CC, Sung PS, Hung CJ, Muo CH, Sung FC, Jou IM, Tsai KJ.

World J Surg. 2018 Mar 14. doi: 10.1007/s00268-018-4573-2. [Epub ahead of print]


Linc00659, a long noncoding RNA, acts as novel oncogene in regulating cancer cell growth in colorectal cancer.

Tsai KW, Lo YH, Liu H, Yeh CY, Chen YZ, Hsu CW, Chen WS, Wang JH.

Mol Cancer. 2018 Mar 10;17(1):72. doi: 10.1186/s12943-018-0821-1.


Musashi-1 promotes chemoresistant granule formation by PKR/eIF2α signalling cascade in refractory glioblastoma.

Chen HY, Lin LT, Wang ML, Tsai KL, Huang PI, Yang YP, Lee YY, Chen YW, Lo WL, Lan YT, Chiou SH, Lin CM, Ma HI, Chen MT.

Biochim Biophys Acta. 2018 Feb 24;1864(5 Pt A):1850-1861. doi: 10.1016/j.bbadis.2018.02.017. [Epub ahead of print]


Melanin Bleaching With Warm Hydrogen Peroxide and Integrated Immunohistochemical Analysis: An Automated Platform.

Liu CH, Lin CH, Tsai MJ, Chen YH, Yang SF, Tsai KB.

Int J Surg Pathol. 2018 Feb 1:1066896918756998. doi: 10.1177/1066896918756998. [Epub ahead of print]


3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound.

Brignole EJ, Tsai KL, Chittuluru J, Li H, Aye Y, Penczek PA, Stubbe J, Drennan CL, Asturias F.

Elife. 2018 Feb 20;7. pii: e31502. doi: 10.7554/eLife.31502.


Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication.

Tsai K, Courtney DG, Cullen BR.

PLoS Pathog. 2018 Feb 15;14(2):e1006919. doi: 10.1371/journal.ppat.1006919. eCollection 2018 Feb.


Unintended Consequences of Evidence-Based Treatment Policy Reform: Is Implementation the Goal or the Strategy for Higher Quality Care?

Park AL, Tsai KH, Guan K, Chorpita BF.

Adm Policy Ment Health. 2018 Feb 14. doi: 10.1007/s10488-018-0853-2. [Epub ahead of print]


Wet depositions of mercury during plum rain season in Taiwan.

Fang GC, Huang WC, Zhuang YJ, Huang CY, Tsai KH, Xiao YF.

Environ Geochem Health. 2018 Feb 12. doi: 10.1007/s10653-018-0074-3. [Epub ahead of print]


Homocysteine causes dysfunction of chondrocytes and oxidative stress through repression of SIRT1/AMPK pathway: A possible link between hyperhomocysteinemia and osteoarthritis.

Ma CH, Chiua YC, Wu CH, Jou IM, Tu YK, Hung CH, Hsieh PL, Tsai KL.

Redox Biol. 2018 May;15:504-512. doi: 10.1016/j.redox.2018.01.010. Epub 2018 Feb 3.


Comparative studies on the hypolipidemic, antioxidant and hepatoprotective activities of catechin-enriched green and oolong tea in a double-blind clinical trial.

Venkatakrishnan K, Chiu HF, Cheng JC, Chang YH, Lu YY, Han YC, Shen YC, Tsai KS, Wang CK.

Food Funct. 2018 Feb 21;9(2):1205-1213. doi: 10.1039/c7fo01449j.


First-Line Helicobacter pylori Eradication in Patients with Chronic Kidney Diseases in Taiwan.

Liang CM, Chiu CH, Wang HM, Tai WC, Yao CC, Tsai CE, Kuo CM, Chiu YC, Wu KL, Lee CH, Tsai KL, Huang CF, Chuah SK.

Biomed Res Int. 2017;2017:3762194. doi: 10.1155/2017/3762194. Epub 2017 Dec 11.


Drug Repurposing Screening Identifies Tioconazole as an ATG4 Inhibitor that Suppresses Autophagy and Sensitizes Cancer Cells to Chemotherapy.

Liu PF, Tsai KL, Hsu CJ, Tsai WL, Cheng JS, Chang HW, Shiau CW, Goan YG, Tseng HH, Wu CH, Reed JC, Yang LW, Shu CW.

Theranostics. 2018 Jan 1;8(3):830-845. doi: 10.7150/thno.22012. eCollection 2018.


An alternative tool for triaging patients with possible acute coronary symptoms before admission to a chest pain unit.

Tsai KC, Lin RF, Lee C, Li AH.

Am J Emerg Med. 2017 Dec 13. pii: S0735-6757(17)31014-8. doi: 10.1016/j.ajem.2017.12.026. [Epub ahead of print]


Peramivir conjugates as orally available agents against influenza H275Y mutant.

Wang PC, Chiu DC, Jan JT, Huang WI, Tseng YC, Li TT, Cheng TJ, Tsai KC, Fang JM.

Eur J Med Chem. 2018 Feb 10;145:224-234. doi: 10.1016/j.ejmech.2017.12.072. Epub 2017 Dec 24.


Neural Mobilization Attenuates Mechanical Allodynia and Decreases Proinflammatory Cytokine Concentrations in Rats With Painful Diabetic Neuropathy.

Zhu GC, Tsai KL, Chen YW, Hung CH.

Phys Ther. 2017 Dec 22. doi: 10.1093/ptj/pzx124. [Epub ahead of print]


Biomimetic heterogenous elastic tissue development.

Tsai KJ, Dixon S, Hale LR, Darbyshire A, Martin D, de Mel A.

NPJ Regen Med. 2017 Jun 8;2:16. doi: 10.1038/s41536-017-0021-4. eCollection 2017.


End stage renal disease is associated with development of dementia.

Hung PH, Yeh CC, Hsiao CY, Sung PS, Muo CH, Sung FC, Hung KY, Tsai KJ.

Oncotarget. 2017 Nov 15;8(64):107348-107355. doi: 10.18632/oncotarget.22458. eCollection 2017 Dec 8.


Association between Helicobacter pylori eradication and the risk of coronary heart diseases.

Wang JW, Tseng KL, Hsu CN, Liang CM, Tai WC, Ku MK, Hung TH, Yuan LT, Nguang SH, Yang SC, Wu CK, Chiu CH, Tsai KL, Chang MW, Huang CF, Hsu PI, Wu DC, Chuah SK.

PLoS One. 2018 Jan 2;13(1):e0190219. doi: 10.1371/journal.pone.0190219. eCollection 2018.


Ten-eleven translocation 1 dysfunction reduces 5-hydroxymethylcytosine expression levels in gastric cancer cells.

Wang KC, Kang CH, Tsai CY, Chou NH, Tu YT, Li GC, Lam HC, Liu SI, Chang PM, Lin YH, Tsai KW.

Oncol Lett. 2018 Jan;15(1):278-284. doi: 10.3892/ol.2017.7264. Epub 2017 Oct 25.


Low Levels of IgG Recognizing the α-1-Antitrypsin Peptide and Its Association with Taiwanese Women with Primary Sjögren's Syndrome.

Chang YS, Pan CH, Chang CC, Tsai KL, Chou HW, Chen JH, Lin SH, Lu YY, Tai CC, Lin YF, Lin CY.

Int J Mol Sci. 2017 Dec 18;18(12). pii: E2750. doi: 10.3390/ijms18122750.


Posttranscriptional m6A Editing of HIV-1 mRNAs Enhances Viral Gene Expression.

Kennedy EM, Bogerd HP, Kornepati AVR, Kang D, Ghoshal D, Marshall JB, Poling BC, Tsai K, Gokhale NS, Horner SM, Cullen BR.

Cell Host Microbe. 2017 Dec 13;22(6):830. doi: 10.1016/j.chom.2017.11.010. No abstract available.


Back to the core: A network approach to bolster harm reduction among persons who inject drugs.

Bouchard M, Hashimi S, Tsai K, Lampkin H, Jozaghi E.

Int J Drug Policy. 2018 Jan;51:95-104. doi: 10.1016/j.drugpo.2017.10.006. Epub 2017 Dec 8.


Distinct TP63 Isoform-Driven Transcriptional Signatures Predict Tumor Progression and Clinical Outcomes.

Abbas HA, Bui NHB, Rajapakshe K, Wong J, Gunaratne P, Tsai KY, Coarfa C, Flores ER.

Cancer Res. 2018 Jan 15;78(2):451-462. doi: 10.1158/0008-5472.CAN-17-1803. Epub 2017 Nov 27.


The effect of the number and level of emergency medical technicians on patient outcomes following out of hospital cardiac arrest in Taipei.

Sun JT, Chiang WC, Hsieh MJ, Huang EP, Yang WS, Chien YC, Wang YC, Lee BC, Sim SS, Tsai KC, Ma MH, Chen LW.

Resuscitation. 2018 Jan;122:48-53. doi: 10.1016/j.resuscitation.2017.11.048. Epub 2017 Nov 21.


Temporary closure of colostomy with suture before colostomy takedown improves the postoperative outcomes.

Hu WH, Lee KC, Tsai KL, Chen HH.

Int J Colorectal Dis. 2018 Jan;33(1):47-52. doi: 10.1007/s00384-017-2934-1. Epub 2017 Nov 22.


Discrimination and Sleep Difficulties during Adolescence: The Mediating Roles of Loneliness and Perceived Stress.

Majeno A, Tsai KM, Huynh VW, McCreath H, Fuligni AJ.

J Youth Adolesc. 2018 Jan;47(1):135-147. doi: 10.1007/s10964-017-0755-8. Epub 2017 Nov 21.


Peramivir analogues bearing hydrophilic side chains exhibit higher activities against H275Y mutant than wild-type influenza virus.

Chiu DC, Lin TC, Huang WI, Cheng TJ, Tsai KC, Fang JM.

Org Biomol Chem. 2017 Nov 29;15(46):9910-9922. doi: 10.1039/c7ob02374j.


Upregulation of PRMT6 by LPS suppresses Klotho expression through interaction with NF-κB in glomerular mesangial cells.

Tsai KD, Lee WX, Chen W, Chen BY, Chen KL, Hsiao TC, Wang SH, Lee YJ, Liang SY, Shieh JC, Lin TH.

J Cell Biochem. 2018 Apr;119(4):3404-3416. doi: 10.1002/jcb.26511. Epub 2018 Jan 4.


Masquelet technique with external locking plate for recalcitrant distal tibial nonunion.

Ma CH, Chiu YC, Tsai KL, Tu YK, Yen CY, Wu CH.

Injury. 2017 Dec;48(12):2847-2852. doi: 10.1016/j.injury.2017.10.037. Epub 2017 Oct 26.


Correlates of depressive symptoms in late middle-aged Taiwanese women: findings from the 2009 Taiwan National Health Interview Survey.

Tsai KW, Lin SC, Koo M.

BMC Womens Health. 2017 Nov 9;17(1):103. doi: 10.1186/s12905-017-0461-4.


Effects of exercise improves muscle strength and fat mass in patients with high fracture risk: A randomized control trial.

Chan DC, Chang CB, Han DS, Hong CH, Hwang JS, Tsai KS, Yang RS.

J Formos Med Assoc. 2017 Oct 26. pii: S0929-6646(17)30101-8. doi: 10.1016/j.jfma.2017.05.004. [Epub ahead of print]


Uncovering protein-protein interactions through a team-based undergraduate biochemistry course.

Cookmeyer DL, Winesett ES, Kokona B, Huff AR, Aliev S, Bloch NB, Bulos JA, Evans IL, Fagre CR, Godbe KN, Khromava M, Konstantinovsky DM, Lafrance AE, Lamacki AJ, Parry RC, Quinn JM, Thurston AM, Tsai KJS, Mollo A, Cryle MJ, Fairman R, Charkoudian LK.

PLoS Biol. 2017 Nov 1;15(11):e2003145. doi: 10.1371/journal.pbio.2003145. eCollection 2017 Nov.


Monitoring tobacco brand websites to understand marketing strategies aimed at tobacco product users and potential users.

Escobedo P, Cruz TB, Tsai KY, Allem JP, Soto DW, Kirkpatrick MG, Pattarroyo M, Unger JB.

Nicotine Tob Res. 2017 Sep 11. doi: 10.1093/ntr/ntx200. [Epub ahead of print]


Primary Endovascular Intervention for Acute Mesenteric Ischemia Performed by Interventional Cardiologists - A Single Center Experience.

Chen TY, Wu CH, Hsu WF, Lin L, Wang RH, Lai CL, Tsai KC, Keng LT, Wu CC, Hsieh MY.

Acta Cardiol Sin. 2017 Jul;33(4):439-446.


Reduced port number in laparoscopic cholecystectomy for acute cholecystitis following percutaneous transhepatic gallbladder drainage.

Tsai KJ, Hsieh PM.

Ann R Coll Surg Engl. 2017 Nov;99(8):658-659. doi: 10.1308/rcsann.2017.0048. Epub 2017 Sep 13. No abstract available.


What are the educational and curriculum needs for emergency medical technicians in Taiwan? A scoping review.

Chang YT, Tsai KC, Williams B.

Adv Med Educ Pract. 2017 Sep 22;8:649-667. doi: 10.2147/AMEP.S140839. eCollection 2017. Review.


A Population-Based Cohort Study on the Drug-Specific Effect of Statins on Sepsis Outcome.

Lee CC, Lee MG, Hsu TC, Porta L, Chang SS, Yo CH, Tsai KC, Lee M.

Chest. 2017 Sep 27. pii: S0012-3692(17)32803-9. doi: 10.1016/j.chest.2017.09.024. [Epub ahead of print]


Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma.

Chang KY, Huang CT, Hsu TI, Hsu CC, Liu JJ, Chuang CK, Hung JJ, Chang WC, Tsai KK, Chuang JY.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):14-19. doi: 10.1016/j.bbrc.2017.09.095. Epub 2017 Sep 19.


The effects of storage temperature and duration of blood samples on DNA and RNA qualities.

Huang LH, Lin PH, Tsai KW, Wang LJ, Huang YH, Kuo HC, Li SC.

PLoS One. 2017 Sep 19;12(9):e0184692. doi: 10.1371/journal.pone.0184692. eCollection 2017.


Clinicopathological study of lip cancer: a retrospective hospital-based study in Taiwan.

Tseng HW, Liou HH, Tsai KW, Ger LP, Shiue YL.

APMIS. 2017 Nov;125(11):1007-1016. doi: 10.1111/apm.12751. Epub 2017 Sep 15.


The effects of house dust mite sublingual immunotherapy tablet on immunologic biomarkers and nasal allergen challenge symptoms.

Gunawardana NC, Zhao Q, Carayannopoulos LN, Tsai K, Malkov VA, Selverian D, Clarke G, Mant T, Butts BD, Lund K, Hansel TT, Nolte H.

J Allergy Clin Immunol. 2018 Feb;141(2):785-788.e9. doi: 10.1016/j.jaci.2017.08.016. Epub 2017 Sep 11. No abstract available.


Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication.

Courtney DG, Kennedy EM, Dumm RE, Bogerd HP, Tsai K, Heaton NS, Cullen BR.

Cell Host Microbe. 2017 Sep 13;22(3):377-386.e5. doi: 10.1016/j.chom.2017.08.004.


Exercise intervention attenuates hyperhomocysteinemia-induced aortic endothelial oxidative injury by regulating SIRT1 through mitigating NADPH oxidase/LOX-1 signaling.

Chan SH, Hung CH, Shih JY, Chu PM, Cheng YH, Lin HC, Hsieh PL, Tsai KL.

Redox Biol. 2018 Apr;14:116-125. doi: 10.1016/j.redox.2017.08.016. Epub 2017 Aug 24.


Isotypes of autoantibodies against differentially expressed novel malondialdehyde-modified peptide adducts in serum of Taiwanese women with rheumatoid arthritis.

Liao CC, Chang YS, Cheng CW, Chi WM, Tsai KL, Chen WJ, Kung TS, Tai CC, Lin YF, Lin HT, Lu YY, Lin CY.

J Proteomics. 2018 Jan 6;170:141-150. doi: 10.1016/j.jprot.2017.08.012. Epub 2017 Sep 1.


PKR activation causes inflammation and MMP-13 secretion in human degenerated articular chondrocytes.

Ma CH, Wu CH, Jou IM, Tu YK, Hung CH, Hsieh PL, Tsai KL.

Redox Biol. 2018 Apr;14:72-81. doi: 10.1016/j.redox.2017.08.011. Epub 2017 Aug 24.

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