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Items: 16


Molecular and structural traits of IRS-1/LC3 nuclear structures and their role in autophagy control and tumor cell survival.

Lassak A, Dean M, Wyczechowska D, Wilk A, Marrero L, Trillo-Tinoco J, Boulares AH, Sarkaria JN, Valle LD, Peruzzi F, Ochoa A, Reiss K.

Mol Cell Biol. 2018 Feb 26. pii: MCB.00608-17. doi: 10.1128/MCB.00608-17. [Epub ahead of print]


Effective antitumor peptide vaccines can induce severe autoimmune pathology.

Sultan H, Trillo-Tinoco J, Rodriguez P, Celis E.

Oncotarget. 2017 Jul 29;8(41):70317-70331. doi: 10.18632/oncotarget.19688. eCollection 2017 Sep 19.


Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance.

Sierra RA, Trillo-Tinoco J, Mohamed E, Yu L, Achyut BR, Arbab A, Bradford JW, Osborne BA, Miele L, Rodriguez PC.

Cancer Res. 2017 Oct 15;77(20):5628-5638. doi: 10.1158/0008-5472.CAN-17-0357. Epub 2017 Sep 13.


Sildenafil Suppresses Inflammation-Driven Colorectal Cancer in Mice.

Islam BN, Sharman SK, Hou Y, Bridges AE, Singh N, Kim S, Kolhe R, Trillo-Tinoco J, Rodriguez PC, Berger FG, Sridhar S, Browning DD.

Cancer Prev Res (Phila). 2017 Jul;10(7):377-388. doi: 10.1158/1940-6207.CAPR-17-0015. Epub 2017 May 3.


Retinoblastoma-binding protein 2 (RBP2) is frequently expressed in neuroendocrine tumors and promotes the neoplastic phenotype.

Maggi EC, Trillo-Tinoco J, Struckhoff AP, Vijayaraghavan J, Del Valle L, Crabtree JS.

Oncogenesis. 2016 Aug 22;5(8):e257. doi: 10.1038/oncsis.2016.58.


A role for MALT1 activity in Kaposi's sarcoma-associated herpes virus latency and growth of primary effusion lymphoma.

Bonsignore L, Passelli K, Pelzer C, Perroud M, Konrad A, Thurau M, Stürzl M, Dai L, Trillo-Tinoco J, Del Valle L, Qin Z, Thome M.

Leukemia. 2017 Mar;31(3):614-624. doi: 10.1038/leu.2016.239. Epub 2016 Aug 19.


CD147 and downstream ADAMTSs promote the tumorigenicity of Kaposi's sarcoma-associated herpesvirus infected endothelial cells.

Dai L, Trillo-Tinoco J, Chen Y, Bonstaff K, Del Valle L, Parsons C, Ochoa AC, Zabaleta J, Toole BP, Qin Z.

Oncotarget. 2016 Jan 26;7(4):3806-18. doi: 10.18632/oncotarget.6584.


The homing receptor CD44 is involved in the progression of precancerous gastric lesions in patients infected with Helicobacter pylori and in development of mucous metaplasia in mice.

Garay J, Piazuelo MB, Majumdar S, Li L, Trillo-Tinoco J, Del Valle L, Schneider BG, Delgado AG, Wilson KT, Correa P, Zabaleta J.

Cancer Lett. 2016 Feb 1;371(1):90-8. doi: 10.1016/j.canlet.2015.10.037. Epub 2015 Nov 27.


Targeting HGF/c-MET induces cell cycle arrest, DNA damage, and apoptosis for primary effusion lymphoma.

Dai L, Trillo-Tinoco J, Cao Y, Bonstaff K, Doyle L, Del Valle L, Whitby D, Parsons C, Reiss K, Zabaleta J, Qin Z.

Blood. 2015 Dec 24;126(26):2821-31. doi: 10.1182/blood-2015-07-658823. Epub 2015 Nov 3.


Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression.

Dai L, Trillo-Tinoco J, Bai A, Chen Y, Bielawski J, Del Valle L, Smith CD, Ochoa AC, Qin Z, Parsons C.

Oncotarget. 2015 Sep 15;6(27):24246-60.


Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies.

Hossain F, Al-Khami AA, Wyczechowska D, Hernandez C, Zheng L, Reiss K, Valle LD, Trillo-Tinoco J, Maj T, Zou W, Rodriguez PC, Ochoa AC.

Cancer Immunol Res. 2015 Nov;3(11):1236-47. doi: 10.1158/2326-6066.CIR-15-0036. Epub 2015 May 29.


The stress-response sensor chop regulates the function and accumulation of myeloid-derived suppressor cells in tumors.

Thevenot PT, Sierra RA, Raber PL, Al-Khami AA, Trillo-Tinoco J, Zarreii P, Ochoa AC, Cui Y, Del Valle L, Rodriguez PC.

Immunity. 2014 Sep 18;41(3):389-401. doi: 10.1016/j.immuni.2014.08.015.


Activation of c-Myc and Cyclin D1 by JCV T-Antigen and β-catenin in colon cancer.

Ripple MJ, Parker Struckhoff A, Trillo-Tinoco J, Li L, Margolin DA, McGoey R, Del Valle L.

PLoS One. 2014 Sep 17;9(9):e106257. doi: 10.1371/journal.pone.0106257. eCollection 2014.


Rescue of notch-1 signaling in antigen-specific CD8+ T cells overcomes tumor-induced T-cell suppression and enhances immunotherapy in cancer.

Sierra RA, Thevenot P, Raber PL, Cui Y, Parsons C, Ochoa AC, Trillo-Tinoco J, Del Valle L, Rodriguez PC.

Cancer Immunol Res. 2014 Aug;2(8):800-11. doi: 10.1158/2326-6066.CIR-14-0021. Epub 2014 May 15.


Systematic analysis of a xenograft mice model for KSHV+ primary effusion lymphoma (PEL).

Dai L, Trillo-Tinoco J, Bai L, Kang B, Xu Z, Wen X, Del Valle L, Qin Z.

PLoS One. 2014 Feb 28;9(2):e90349. doi: 10.1371/journal.pone.0090349. eCollection 2014.


Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma.

Qin Z, Dai L, Trillo-Tinoco J, Senkal C, Wang W, Reske T, Bonstaff K, Del Valle L, Rodriguez P, Flemington E, Voelkel-Johnson C, Smith CD, Ogretmen B, Parsons C.

Mol Cancer Ther. 2014 Jan;13(1):154-64. doi: 10.1158/1535-7163.MCT-13-0466. Epub 2013 Oct 18.

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