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Items: 1 to 50 of 91


The cardio-metabolic impact of taking commonly prescribed analgesic drugs in 133,401 UK Biobank participants.

Cassidy S, Trenell MI, Anderson KN.

PLoS One. 2017 Dec 6;12(12):e0187982. doi: 10.1371/journal.pone.0187982. eCollection 2017.


Impact of age-related mitochondrial dysfunction and exercise on intestinal microbiota composition.

Houghton D, Stewart CJ, Stamp C, Nelson A, Ajami NJ, Petrosino JF, Wipat A, Trenell MI, Turnbull DM, Greaves LC.

J Gerontol A Biol Sci Med Sci. 2017 Oct 16. doi: 10.1093/gerona/glx197. [Epub ahead of print]


Pathophysiology of exercise intolerance in chronic diseases: the role of diminished cardiac performance in mitochondrial and heart failure patients.

McCoy J, Bates M, Eggett C, Siervo M, Cassidy S, Newman J, Moore SA, Gorman G, Trenell MI, Velicki L, Seferovic PM, Cleland JGF, MacGowan GA, Turnbull DM, Jakovljevic DG.

Open Heart. 2017 Jul 28;4(2):e000632. doi: 10.1136/openhrt-2017-000632. eCollection 2017.


Lifestyle Behavior Change in Patients With Nonalcoholic Fatty Liver Disease: A Qualitative Study of Clinical Practice.

Avery L, Exley C, McPherson S, Trenell MI, Anstee QM, Hallsworth K.

Clin Gastroenterol Hepatol. 2017 Dec;15(12):1968-1971. doi: 10.1016/j.cgh.2017.06.011. Epub 2017 Jun 15. No abstract available.


Impact of age on the association between cardiac high-energy phosphate metabolism and cardiac power in women.

Nathania M, Hollingsworth KG, Bates M, Eggett C, Trenell MI, Velicki L, Seferovic PM, MacGowan GA, Turnbull DM, Jakovljevic DG.

Heart. 2018 Jan;104(2):111-118. doi: 10.1136/heartjnl-2017-311275. Epub 2017 Jun 12.


Comparison of cardiac output estimates by bioreactance and inert gas rebreathing methods during cardiopulmonary exercise testing.

Okwose NC, Chowdhury S, Houghton D, Trenell MI, Eggett C, Bates M, MacGowan GA, Jakovljevic DG.

Clin Physiol Funct Imaging. 2017 Jun 2. doi: 10.1111/cpf.12442. [Epub ahead of print]


Effects of Exercise on Liver Fat and Metabolism in Alcohol Drinkers.

Houghton D, Hallsworth K, Thoma C, Cassidy S, Hardy T, Heaps S, Hollingsworth KG, Taylor R, Day CP, Masson S, McPherson S, Anstee QM, Trenell MI.

Clin Gastroenterol Hepatol. 2017 Oct;15(10):1596-1603.e3. doi: 10.1016/j.cgh.2017.05.001. Epub 2017 May 10.


Low physical activity, high television viewing and poor sleep duration cluster in overweight and obese adults; a cross-sectional study of 398,984 participants from the UK Biobank.

Cassidy S, Chau JY, Catt M, Bauman A, Trenell MI.

Int J Behav Nutr Phys Act. 2017 Apr 28;14(1):57. doi: 10.1186/s12966-017-0514-y.


Measuring Habitual Physical Activity in Neuromuscular Disorders: A Systematic Review.

Jimenez-Moreno AC, Newman J, Charman SJ, Catt M, Trenell MI, Gorman GS, Hogrel JY, Lochmüller H.

J Neuromuscul Dis. 2017;4(1):25-52. doi: 10.3233/JND-160195. Review.


Large Scale Population Assessment of Physical Activity Using Wrist Worn Accelerometers: The UK Biobank Study.

Doherty A, Jackson D, Hammerla N, Plötz T, Olivier P, Granat MH, White T, van Hees VT, Trenell MI, Owen CG, Preece SJ, Gillions R, Sheard S, Peakman T, Brage S, Wareham NJ.

PLoS One. 2017 Feb 1;12(2):e0169649. doi: 10.1371/journal.pone.0169649. eCollection 2017.


The effect of percutaneous coronary intervention on habitual physical activity in older patients.

Charman SJ, van Hees VT, Quinn L, Dunford JR, Bawamia B, Veerasamy M, Trenell MI, Jakovljevic DG, Kunadian V.

BMC Cardiovasc Disord. 2016 Dec 3;16(1):248.


Does the liver accelerate ageing: Talking muscles and liver?

Trenell MI, Marchesini G.

J Hepatol. 2017 Jan;66(1):8-10. doi: 10.1016/j.jhep.2016.10.018. Epub 2016 Oct 24. No abstract available.


Exercise Reduces Liver Lipids and Visceral Adiposity in Patients With Nonalcoholic Steatohepatitis in a Randomized Controlled Trial.

Houghton D, Thoma C, Hallsworth K, Cassidy S, Hardy T, Burt AD, Tiniakos D, Hollingsworth KG, Taylor R, Day CP, McPherson S, Anstee QM, Trenell MI.

Clin Gastroenterol Hepatol. 2017 Jan;15(1):96-102.e3. doi: 10.1016/j.cgh.2016.07.031. Epub 2016 Aug 10.


Exercise-induced improvements in liver fat and endothelial function are not sustained 12 months following cessation of exercise supervision in nonalcoholic fatty liver disease.

Pugh CJ, Sprung VS, Jones H, Richardson P, Shojaee-Moradie F, Umpleby AM, Green DJ, Cable NT, Trenell MI, Kemp GJ, Cuthbertson DJ.

Int J Obes (Lond). 2016 Dec;40(12):1927-1930. doi: 10.1038/ijo.2016.123. Epub 2016 Jul 21.


Age-related decline in cardiac autonomic function is not attenuated with increased physical activity.

Njemanze H, Warren C, Eggett C, MacGowan GA, Bates MG, Siervo M, Ivkovic S, Trenell MI, Jakovljevic DG.

Oncotarget. 2016 Nov 22;7(47):76390-76397. doi: 10.18632/oncotarget.12403.


A study of physical activity comparing people with Charcot-Marie-Tooth disease to normal control subjects.

Ramdharry GM, Pollard AJ, Grant R, Dewar EL, Laurá M, Moore SA, Hallsworth K, Ploetz T, Trenell MI, Reilly MM.

Disabil Rehabil. 2017 Aug;39(17):1753-1758. doi: 10.1080/09638288.2016.1211180. Epub 2016 Aug 16.


High-intensity interval training: a review of its impact on glucose control and cardiometabolic health.

Cassidy S, Thoma C, Houghton D, Trenell MI.

Diabetologia. 2017 Jan;60(1):7-23. Epub 2016 Sep 28. Review.


Systematic development of a theory-informed multifaceted behavioural intervention to increase physical activity of adults with type 2 diabetes in routine primary care: Movement as Medicine for Type 2 Diabetes.

Avery L, Charman SJ, Taylor L, Flynn D, Mosely K, Speight J, Lievesley M, Taylor R, Sniehotta FF, Trenell MI.

Implement Sci. 2016 Jul 19;11:99. doi: 10.1186/s13012-016-0459-6.


Exercise therapy in primary biliary cirrhosis: the importance of moving while sitting on a surgical waiting list-a case study.

Hallsworth K, Jopson L, Jones DE, Trenell MI.

Frontline Gastroenterol. 2016 Jul;7(3):167-169. Epub 2016 Apr 12.


Relationship between bioreactance and magnetic resonance imaging stroke volumes.

Perkins RE, Hollingsworth KG, Eggett C, MacGowan GA, Bates MG, Trenell MI, Jakovljevic DG.

Br J Anaesth. 2016 Jul;117(1):134-6. doi: 10.1093/bja/aew164. No abstract available.


Prevalence and risk factors for prolonged QT interval and QT dispersion in patients with type 2 diabetes.

Ninkovic VM, Ninkovic SM, Miloradovic V, Stanojevic D, Babic M, Giga V, Dobric M, Trenell MI, Lalic N, Seferovic PM, Jakovljevic DG.

Acta Diabetol. 2016 Oct;53(5):737-44. doi: 10.1007/s00592-016-0864-y. Epub 2016 Apr 23.


Sucrose ingestion after exhaustive exercise accelerates liver, but not muscle glycogen repletion compared with glucose ingestion in trained athletes.

Fuchs CJ, Gonzalez JT, Beelen M, Cermak NM, Smith FE, Thelwall PE, Taylor R, Trenell MI, Stevenson EJ, van Loon LJ.

J Appl Physiol (1985). 2016 Jun 1;120(11):1328-34. doi: 10.1152/japplphysiol.01023.2015. Epub 2016 Mar 24.


Targeting Lifestyle Behavior Change in Adults with NAFLD During a 20-min Consultation: Summary of the Dietary and Exercise Literature.

Hallsworth K, Avery L, Trenell MI.

Curr Gastroenterol Rep. 2016 Mar;18(3):11. doi: 10.1007/s11894-016-0485-1. Review.


Exercise Induces Peripheral Muscle But Not Cardiac Adaptations After Stroke: A Randomized Controlled Pilot Trial.

Moore SA, Jakovljevic DG, Ford GA, Rochester L, Trenell MI.

Arch Phys Med Rehabil. 2016 Apr;97(4):596-603. doi: 10.1016/j.apmr.2015.12.018. Epub 2016 Jan 4.


The effect of age on the relationship between cardiac and vascular function.

Houghton D, Jones TW, Cassidy S, Siervo M, MacGowan GA, Trenell MI, Jakovljevic DG.

Mech Ageing Dev. 2016 Jan;153:1-6. doi: 10.1016/j.mad.2015.11.001. Epub 2015 Nov 15.


A Novel, Open Access Method to Assess Sleep Duration Using a Wrist-Worn Accelerometer.

van Hees VT, Sabia S, Anderson KN, Denton SJ, Oliver J, Catt M, Abell JG, Kivimäki M, Trenell MI, Singh-Manoux A.

PLoS One. 2015 Nov 16;10(11):e0142533. doi: 10.1371/journal.pone.0142533. eCollection 2015.


Ingestion of glucose or sucrose prevents liver but not muscle glycogen depletion during prolonged endurance-type exercise in trained cyclists.

Gonzalez JT, Fuchs CJ, Smith FE, Thelwall PE, Taylor R, Stevenson EJ, Trenell MI, Cermak NM, van Loon LJ.

Am J Physiol Endocrinol Metab. 2015 Dec 15;309(12):E1032-9. doi: 10.1152/ajpendo.00376.2015. Epub 2015 Oct 20.


High intensity intermittent exercise improves cardiac structure and function and reduces liver fat in patients with type 2 diabetes: a randomised controlled trial.

Cassidy S, Thoma C, Hallsworth K, Parikh J, Hollingsworth KG, Taylor R, Jakovljevic DG, Trenell MI.

Diabetologia. 2016 Jan;59(1):56-66. doi: 10.1007/s00125-015-3741-2. Epub 2015 Sep 9.


Sedentary behaviour, physical activity, and NAFLD: Curse of the chair.

Trenell MI.

J Hepatol. 2015 Nov;63(5):1064-5. doi: 10.1016/j.jhep.2015.08.009. Epub 2015 Aug 20. No abstract available.


Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: a randomized controlled trial.

Hallsworth K, Thoma C, Hollingsworth KG, Cassidy S, Anstee QM, Day CP, Trenell MI.

Clin Sci (Lond). 2015 Dec;129(12):1097-105. doi: 10.1042/CS20150308. Epub 2015 Aug 11.


Preliminary Evaluation of Clinician Rated Outcome Measures in Mitochondrial Disease.

Newman J, Galna B, Jakovljevic DG, Bates MG, Schaefer AM, McFarland R, Turnbull DM, Trenell MI, Taylor RW, Rochester L, Gorman GS.

J Neuromuscul Dis. 2015 Jun 4;2(2):151-155.


Cardiac structure and function are altered in type 2 diabetes and non-alcoholic fatty liver disease and associate with glycemic control.

Cassidy S, Hallsworth K, Thoma C, MacGowan GA, Hollingsworth KG, Day CP, Taylor R, Jakovljevic DG, Trenell MI.

Cardiovasc Diabetol. 2015 Feb 13;14:23. doi: 10.1186/s12933-015-0187-2.


Successful behavioural strategies to increase physical activity and improve glucose control in adults with Type 2 diabetes.

Avery L, Flynn D, Dombrowski SU, van Wersch A, Sniehotta FF, Trenell MI.

Diabet Med. 2015 Aug;32(8):1058-62. doi: 10.1111/dme.12738. Epub 2015 Apr 1. Review.


Bioreactance is a reliable method for estimating cardiac output at rest and during exercise.

Jones TW, Houghton D, Cassidy S, MacGowan GA, Trenell MI, Jakovljevic DG.

Br J Anaesth. 2015 Sep;115(3):386-91. doi: 10.1093/bja/aeu560. Epub 2015 Feb 6.


Novel MTND1 mutations cause isolated exercise intolerance, complex I deficiency and increased assembly factor expression.

Gorman GS, Blakely EL, Hornig-Do HT, Tuppen HA, Greaves LC, He L, Baker A, Falkous G, Newman J, Trenell MI, Lecky B, Petty RK, Turnbull DM, McFarland R, Taylor RW.

Clin Sci (Lond). 2015 Jun;128(12):895-904. doi: 10.1042/CS20140705.


Non-alcoholic fatty liver disease is associated with higher levels of objectively measured sedentary behaviour and lower levels of physical activity than matched healthy controls.

Hallsworth K, Thoma C, Moore S, Ploetz T, Anstee QM, Taylor R, Day CP, Trenell MI.

Frontline Gastroenterol. 2015 Jan;6(1):44-51. Epub 2014 Jun 30.


Effect of physical activity on age-related changes in cardiac function and performance in women.

Jakovljevic DG, Papakonstantinou L, Blamire AM, MacGowan GA, Taylor R, Hollingsworth KG, Trenell MI.

Circ Cardiovasc Imaging. 2014 Dec 30;8(1). pii: e002086. doi: 10.1161/CIRCIMAGING.114.002086. Print 2015 Jan.


Effects of Community Exercise Therapy on Metabolic, Brain, Physical, and Cognitive Function Following Stroke: A Randomized Controlled Pilot Trial.

Moore SA, Hallsworth K, Jakovljevic DG, Blamire AM, He J, Ford GA, Rochester L, Trenell MI.

Neurorehabil Neural Repair. 2015 Aug;29(7):623-35. doi: 10.1177/1545968314562116. Epub 2014 Dec 23.


Bioimpedance and bioreactance methods for monitoring cardiac output.

Jakovljevic DG, Trenell MI, MacGowan GA.

Best Pract Res Clin Anaesthesiol. 2014 Dec;28(4):381-94. doi: 10.1016/j.bpa.2014.09.003. Epub 2014 Sep 23.


Autocalibration of accelerometer data for free-living physical activity assessment using local gravity and temperature: an evaluation on four continents.

van Hees VT, Fang Z, Langford J, Assah F, Mohammad A, da Silva IC, Trenell MI, White T, Wareham NJ, Brage S.

J Appl Physiol (1985). 2014 Oct 1;117(7):738-44. doi: 10.1152/japplphysiol.00421.2014. Epub 2014 Aug 7.


Effect of left ventricular assist device implantation and heart transplantation on habitual physical activity and quality of life.

Jakovljevic DG, McDiarmid A, Hallsworth K, Seferovic PM, Ninkovic VM, Parry G, Schueler S, Trenell MI, MacGowan GA.

Am J Cardiol. 2014 Jul 1;114(1):88-93. doi: 10.1016/j.amjcard.2014.04.008. Epub 2014 Apr 18.


Metabolic implications when employing heavy pre- and post-exercise rapid-acting insulin reductions to prevent hypoglycaemia in type 1 diabetes patients: a randomised clinical trial.

Campbell MD, Walker M, Trenell MI, Luzio S, Dunseath G, Tuner D, Bracken RM, Bain SC, Russell M, Stevenson EJ, West DJ.

PLoS One. 2014 May 23;9(5):e97143. doi: 10.1371/journal.pone.0097143. eCollection 2014.


A low-glycemic index meal and bedtime snack prevents postprandial hyperglycemia and associated rises in inflammatory markers, providing protection from early but not late nocturnal hypoglycemia following evening exercise in type 1 diabetes.

Campbell MD, Walker M, Trenell MI, Stevenson EJ, Turner D, Bracken RM, Shaw JA, West DJ.

Diabetes Care. 2014 Jul;37(7):1845-53. doi: 10.2337/dc14-0186. Epub 2014 May 1.


Association between questionnaire- and accelerometer-assessed physical activity: the role of sociodemographic factors.

Sabia S, van Hees VT, Shipley MJ, Trenell MI, Hagger-Johnson G, Elbaz A, Kivimaki M, Singh-Manoux A.

Am J Epidemiol. 2014 Mar 15;179(6):781-90. doi: 10.1093/aje/kwt330. Epub 2014 Feb 4.


Growth and metabolic outcome in adolescents born preterm (GROWMORE): follow-up protocol for the Newcastle Preterm Birth GRowth study (PTBGS).

Wood CL, Tinnion RJ, Korada SM, Cheetham TD, Relton CL, Cooke RJ, Pearce MS, Hollingsworth KG, Trenell MI, Embleton ND.

BMC Pediatr. 2013 Dec 20;13:213. doi: 10.1186/1471-2431-13-213.


Discrete gait characteristics are associated with m.3243A>G and m.8344A>G variants of mitochondrial disease and its pathological consequences.

Galna B, Newman J, Jakovljevic DG, Bates MG, Schaefer AM, McFarland R, Turnbull DM, Trenell MI, Gorman GS, Rochester L.

J Neurol. 2014 Jan;261(1):73-82. doi: 10.1007/s00415-013-7129-2. Epub 2013 Oct 23.


Impaired cardiopulmonary reserve in an elderly population is related to postoperative morbidity and length of hospital stay after radical cystectomy.

Prentis JM, Trenell MI, Vasdev N, French R, Dines G, Thorpe A, Snowden CP.

BJU Int. 2013 Jul;112(2):E13-9. doi: 10.1111/bju.12219.


Defining cardiac adaptations and safety of endurance training in patients with m.3243A>G-related mitochondrial disease.

Bates MG, Newman JH, Jakovljevic DG, Hollingsworth KG, Alston CL, Zalewski P, Klawe JJ, Blamire AM, MacGowan GA, Keavney BD, Bourke JP, Schaefer A, McFarland R, Newton JL, Turnbull DM, Taylor RW, Trenell MI, Gorman GS.

Int J Cardiol. 2013 Oct 9;168(4):3599-608. doi: 10.1016/j.ijcard.2013.05.062. Epub 2013 Jun 3.

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