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Items: 30


Influence of intra-tumoral heterogeneity on the evaluation of BCL2, E-cadherin, EGFR, EMMPRIN, and Ki-67 expression in tissue microarrays from breast cancer.

Tramm T, Kyndi M, Sørensen FB, Overgaard J, Alsner J.

Acta Oncol. 2018 Jan;57(1):102-106. doi: 10.1080/0284186X.2017.1404128. Epub 2017 Dec 4.


Intrinsic subtypes and benefit from postmastectomy radiotherapy in node-positive premenopausal breast cancer patients who received adjuvant chemotherapy - results from two independent randomized trials.

Laurberg T, Tramm T, Nielsen T, Alsner J, Nord S, Myhre S, Sørlie T, Leung S, Fan C, Perou C, Gelmon K, Overgaard J, Voduc D, Prat A, Cheang MCU.

Acta Oncol. 2018 Jan;57(1):38-43. doi: 10.1080/0284186X.2017.1401735. Epub 2017 Nov 25.


Standardized assessment of tumor-infiltrating lymphocytes in breast cancer: an evaluation of inter-observer agreement between pathologists.

Tramm T, Di Caterino T, Jylling AB, Lelkaitis G, Lænkholm AV, Ragó P, Tabor TP, Talman MM, Vouza E; Scientific Committee of Pathology, Danish Breast Cancer Group (DBCG).

Acta Oncol. 2018 Jan;57(1):90-94. doi: 10.1080/0284186X.2017.1403040. Epub 2017 Nov 23.


Normal and Malignant Cells Exhibit Differential Responses to Calcium Electroporation.

Frandsen SK, Krüger MB, Mangalanathan UM, Tramm T, Mahmood F, Novak I, Gehl J.

Cancer Res. 2017 Aug 15;77(16):4389-4401. doi: 10.1158/0008-5472.CAN-16-1611. Epub 2017 Jul 31.


Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome.

Aure MR, Vitelli V, Jernström S, Kumar S, Krohn M, Due EU, Haukaas TH, Leivonen SK, Vollan HK, Lüders T, Rødland E, Vaske CJ, Zhao W, Møller EK, Nord S, Giskeødegård GF, Bathen TF, Caldas C, Tramm T, Alsner J, Overgaard J, Geisler J, Bukholm IR, Naume B, Schlichting E, Sauer T, Mills GB, Kåresen R, Mælandsmo GM, Lingjærde OC, Frigessi A, Kristensen VN, Børresen-Dale AL, Sahlberg KK; OSBREAC.

Breast Cancer Res. 2017 Mar 29;19(1):44. doi: 10.1186/s13058-017-0812-y.


Impact of age, intrinsic subtype and local treatment on long-term local-regional recurrence and breast cancer mortality among low-risk breast cancer patients.

Laurberg T, Alsner J, Tramm T, Jensen V, Lyngholm CD, Christiansen PM, Overgaard J.

Acta Oncol. 2017 Jan;56(1):59-67. doi: 10.1080/0284186X.2016.1246803. Epub 2016 Nov 16.


Co-expression of p16 and p53 characterizes aggressive subtypes of ductal intraepithelial neoplasia.

Bechert C, Kim JY, Tramm T, Tavassoli FA.

Virchows Arch. 2016 Dec;469(6):659-667. Epub 2016 Sep 23.


Expression of C-KIT, CD24, CD44s, and COX2 in benign and non-invasive apocrine lesions of the breast.

Tramm T, Kim JY, Leibl S, Moinfar F, Tavassoli FA.

Virchows Arch. 2016 Sep;469(3):285-95. doi: 10.1007/s00428-016-1966-1. Epub 2016 Jun 10.


Validation of a 15-gene hypoxia classifier in head and neck cancer for prospective use in clinical trials.

Toustrup K, Sørensen BS, Metwally MA, Tramm T, Mortensen LS, Overgaard J, Alsner J.

Acta Oncol. 2016 Sep - Oct;55(9-10):1091-1098. doi: 10.3109/0284186X.2016.1167959. Epub 2016 May 10.


Clinical Impact of a Novel MicroRNA Chemo-Sensitivity Predictor in Gastrooesophageal Cancer.

Winther M, Knudsen S, Dahlgaard J, Jensen T, Hansen A, Jensen PB, Tramm T, Alsner J, Nordsmark M.

PLoS One. 2016 Feb 17;11(2):e0148070. doi: 10.1371/journal.pone.0148070. eCollection 2016.


Hypoxia-regulated MicroRNAs in Gastroesophageal Cancer.

Winther M, Alsner J, Sørensen BS, Wittrup CF, Tramm T, Baeksgaard L, Hofland K, Holtved E, Nordsmark M.

Anticancer Res. 2016 Feb;36(2):721-30.


Prognostic value of hypoxia-regulated gene expression in loco-regional gastroesophageal cancer.

Winther M, Alsner J, Tramm T, Holtved E, Baeksgaard L, Nordsmark M.

Acta Oncol. 2016 May;55(5):652-5. doi: 10.3109/0284186X.2015.1114680. Epub 2015 Dec 1. No abstract available.


Evaluation of miR-21 and miR-375 as prognostic biomarkers in esophageal cancer.

Winther M, Alsner J, Tramm T, Baeksgaard L, Holtved E, Nordsmark M.

Acta Oncol. 2015;54(9):1582-91. doi: 10.3109/0284186X.2015.1064161.


PAPP-A proteolytic activity enhances IGF bioactivity in ascites from women with ovarian carcinoma.

Thomsen J, Hjortebjerg R, Espelund U, Ørtoft G, Vestergaard P, Magnusson NE, Conover CA, Tramm T, Hager H, Høgdall C, Høgdall E, Oxvig C, Frystyk J.

Oncotarget. 2015 Oct 13;6(31):32266-78. doi: 10.18632/oncotarget.5010.


Development and validation of a gene profile predicting benefit of postmastectomy radiotherapy in patients with high-risk breast cancer: a study of gene expression in the DBCG82bc cohort.

Tramm T, Mohammed H, Myhre S, Kyndi M, Alsner J, Børresen-Dale AL, Sørlie T, Frigessi A, Overgaard J.

Clin Cancer Res. 2014 Oct 15;20(20):5272-80. doi: 10.1158/1078-0432.CCR-14-0458. Epub 2014 Aug 22.


Relationship between the prognostic and predictive value of the intrinsic subtypes and a validated gene profile predictive of loco-regional control and benefit from post-mastectomy radiotherapy in patients with high-risk breast cancer.

Tramm T, Kyndi M, Myhre S, Nord S, Alsner J, Sørensen FB, Sørlie T, Overgaard J.

Acta Oncol. 2014 Oct;53(10):1337-46. doi: 10.3109/0284186X.2014.925580. Epub 2014 Jun 24.


Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c.

Nygren MK, Tekle C, Ingebrigtsen VA, Mäkelä R, Krohn M, Aure MR, Nunes-Xavier CE, Perälä M, Tramm T, Alsner J, Overgaard J, Nesland JM, Borgen E, Børresen-Dale AL, Fodstad Ø, Sahlberg KK, Leivonen SK.

Br J Cancer. 2014 Apr 15;110(8):2072-80. doi: 10.1038/bjc.2014.113. Epub 2014 Feb 27.


The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors.

Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V.

Mol Oncol. 2014 Mar;8(2):273-84. doi: 10.1016/j.molonc.2013.11.008. Epub 2013 Dec 3.


Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors.

Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN.

Genome Biol. 2013 Nov 20;14(11):R126. doi: 10.1186/gb-2013-14-11-r126.


Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection.

Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J.

Virchows Arch. 2013 Dec;463(6):775-86. doi: 10.1007/s00428-013-1486-1. Epub 2013 Oct 8.


Hypoxia-regulated gene expression and prognosis in loco-regional gastroesophageal cancer.

Winther M, Alsner J, Tramm T, Nordsmark M.

Acta Oncol. 2013 Oct;52(7):1327-35. doi: 10.3109/0284186X.2013.818247. Epub 2013 Aug 19.


Optimal reference genes for normalization of qRT-PCR data from archival formalin-fixed, paraffin-embedded breast tumors controlling for tumor cell content and decay of mRNA.

Tramm T, Sørensen BS, Overgaard J, Alsner J.

Diagn Mol Pathol. 2013 Sep;22(3):181-7. doi: 10.1097/PDM.0b013e318285651e.


Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins.

Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T.

Mol Oncol. 2013 Jun;7(3):704-18. doi: 10.1016/j.molonc.2013.02.018. Epub 2013 Mar 19.


Combretastatin A-4 phosphate affects tumor vessel volume and size distribution as assessed using MRI-based vessel size imaging.

Nielsen T, Bentzen L, Pedersen M, Tramm T, Rijken PF, Bussink J, Horsman MR, Østergaard L.

Clin Cancer Res. 2012 Dec 1;18(23):6469-77. doi: 10.1158/1078-0432.CCR-12-2014. Epub 2012 Oct 15.


Direct therapeutic applications of calcium electroporation to effectively induce tumor necrosis.

Frandsen SK, Gissel H, Hojman P, Tramm T, Eriksen J, Gehl J.

Cancer Res. 2012 Mar 15;72(6):1336-41. doi: 10.1158/0008-5472.CAN-11-3782. Epub 2012 Jan 26.


Diminished number or complete loss of myoepithelial cells associated with metaplastic and neoplastic apocrine lesions of the breast.

Tramm T, Kim JY, Tavassoli FA.

Am J Surg Pathol. 2011 Feb;35(2):202-11. doi: 10.1097/PAS.0b013e31820598a2.


In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome.

Myhre S, Mohammed H, Tramm T, Alsner J, Finak G, Park M, Overgaard J, Børresen-Dale AL, Frigessi A, Sørlie T.

PLoS One. 2010 Nov 19;5(11):e14002. doi: 10.1371/journal.pone.0014002.


HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer.

Lassen P, Eriksen JG, Hamilton-Dutoit S, Tramm T, Alsner J, Overgaard J; Danish Head and Neck Cancer Group (DAHANCA).

Radiother Oncol. 2010 Jan;94(1):30-5. doi: 10.1016/j.radonc.2009.10.008. Epub 2009 Nov 10.


Skip lesion of DIN (DCIS) in the nipple in a case of breast cancer.

Tramm T, Zuckerman K, Tavassoli FA.

Int J Surg Pathol. 2011 Dec;19(6):817-21. doi: 10.1177/1066896909339737. Epub 2009 Jul 3.


Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck.

Lassen P, Eriksen JG, Hamilton-Dutoit S, Tramm T, Alsner J, Overgaard J.

J Clin Oncol. 2009 Apr 20;27(12):1992-8. doi: 10.1200/JCO.2008.20.2853. Epub 2009 Mar 16.


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