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Items: 37

1.

Positron emission tomography (PET) imaging of tumor-localized Salmonella expressing HSV1-TK.

Soghomonyan SA, Doubrovin M, Pike J, Luo X, Ittensohn M, Runyan JD, Balatoni J, Finn R, Tjuvajev JG, Blasberg R, Bermudes D.

Cancer Gene Ther. 2005 Jan;12(1):101-8.

PMID:
15499377
2.
3.

Development of a new reporter gene system--dsRed/xanthine phosphoribosyltransferase-xanthine for molecular imaging of processes behind the intact blood-brain barrier.

Doubrovin M, Ponomarev V, Serganova I, Soghomonian S, Myagawa T, Beresten T, Ageyeva L, Sadelain M, Koutcher J, Blasberg RG, Tjuvajev JG.

Mol Imaging. 2003 Apr;2(2):93-112.

PMID:
12964307
4.

Imaging expression of cytosine deaminase-herpes virus thymidine kinase fusion gene (CD/TK) expression with [124I]FIAU and PET.

Hackman T, Doubrovin M, Balatoni J, Beresten T, Ponomarev V, Beattie B, Finn R, Bornmann W, Blasberg R, Tjuvajev JG.

Mol Imaging. 2002 Jan-Mar;1(1):36-42.

PMID:
12920859
5.

Cytoplasmically retargeted HSV1-tk/GFP reporter gene mutants for optimization of noninvasive molecular-genetic imaging.

Ponomarev V, Doubrovin M, Serganova I, Beresten T, Vider J, Shavrin A, Ageyeva L, Balatoni J, Blasberg R, Tjuvajev JG.

Neoplasia. 2003 May-Jun;5(3):245-54. doi: 10.1016/S1476-5586(03)80056-8.

6.

Molecular-genetic imaging: current and future perspectives.

Blasberg RG, Tjuvajev JG.

J Clin Invest. 2003 Jun;111(11):1620-9. Review. No abstract available.

7.

Imaging of dihydrofolate reductase fusion gene expression in xenografts of human liver metastases of colorectal cancer in living rats.

Mayer-Kuckuk P, Doubrovin M, Gusani NJ, Gade T, Balatoni J, Akhurst T, Finn R, Fong Y, Koutcher JA, Larson S, Blasberg R, Tjuvajev JG, Bertino JR, Banerjee D.

Eur J Nucl Med Mol Imaging. 2003 Sep;30(9):1281-91. Epub 2003 Mar 27.

PMID:
12664136
8.

Serial in vivo imaging of the targeted migration of human HSV-TK-transduced antigen-specific lymphocytes.

Koehne G, Doubrovin M, Doubrovina E, Zanzonico P, Gallardo HF, Ivanova A, Balatoni J, Teruya-Feldstein J, Heller G, May C, Ponomarev V, Ruan S, Finn R, Blasberg RG, Bornmann W, Riviere I, Sadelain M, O'Reilly RJ, Larson SM, Tjuvajev JG.

Nat Biotechnol. 2003 Apr;21(4):405-13. Epub 2003 Mar 24.

PMID:
12652311
9.

In vivo multiple-mouse imaging at 1.5 T.

Xu S, Gade TP, Matei C, Zakian K, Alfieri AA, Hu X, Holland EC, Soghomonian S, Tjuvajev J, Ballon D, Koutcher JA.

Magn Reson Med. 2003 Mar;49(3):551-7.

10.

Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression.

Tjuvajev JG, Doubrovin M, Akhurst T, Cai S, Balatoni J, Alauddin MM, Finn R, Bornmann W, Thaler H, Conti PS, Blasberg RG.

J Nucl Med. 2002 Aug;43(8):1072-83.

11.

Tumor-specific transcriptional targeting of suicide gene therapy.

Qiao J, Doubrovin M, Sauter BV, Huang Y, Guo ZS, Balatoni J, Akhurst T, Blasberg RG, Tjuvajev JG, Chen SH, Woo SL.

Gene Ther. 2002 Feb;9(3):168-75.

12.

Imaging TCR-dependent NFAT-mediated T-cell activation with positron emission tomography in vivo.

Ponomarev V, Doubrovin M, Lyddane C, Beresten T, Balatoni J, Bornman W, Finn R, Akhurst T, Larson S, Blasberg R, Sadelain M, Tjuvajev JG.

Neoplasia. 2001 Nov-Dec;3(6):480-8.

13.

Salmonella-based tumor-targeted cancer therapy: tumor amplified protein expression therapy (TAPET) for diagnostic imaging.

Tjuvajev J, Blasberg R, Luo X, Zheng LM, King I, Bermudes D.

J Control Release. 2001 Jul 6;74(1-3):313-5.

PMID:
11489512
14.

Positron emission tomography imaging for herpes virus infection: Implications for oncolytic viral treatments of cancer.

Bennett JJ, Tjuvajev J, Johnson P, Doubrovin M, Akhurst T, Malholtra S, Hackman T, Balatoni J, Finn R, Larson SM, Federoff H, Blasberg R, Fong Y.

Nat Med. 2001 Jul;7(7):859-63.

PMID:
11433353
15.

Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo.

Jacobs A, Tjuvajev JG, Dubrovin M, Akhurst T, Balatoni J, Beattie B, Joshi R, Finn R, Larson SM, Herrlinger U, Pechan PA, Chiocca EA, Breakefield XO, Blasberg RG.

Cancer Res. 2001 Apr 1;61(7):2983-95.

16.

A general approach to the non-invasive imaging of transgenes using cis-linked herpes simplex virus thymidine kinase.

Tjuvajev JG, Joshi A, Callegari J, Lindsley L, Joshi R, Balatoni J, Finn R, Larson SM, Sadelain M, Blasberg RG.

Neoplasia. 1999 Oct;1(4):315-20.

17.

Imaging transgene expression with radionuclide imaging technologies.

Gambhir SS, Herschman HR, Cherry SR, Barrio JR, Satyamurthy N, Toyokuni T, Phelps ME, Larson SM, Balatoni J, Finn R, Sadelain M, Tjuvajev J, Blasberg R.

Neoplasia. 2000 Jan-Apr;2(1-2):118-38. Review.

18.

Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: implications for noninvasive imaging of transgene expression.

Jacobs A, Dubrovin M, Hewett J, Sena-Esteves M, Tan CW, Slack M, Sadelain M, Breakefield XO, Tjuvajev JG.

Neoplasia. 1999 Jun;1(2):154-61.

19.

Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo.

Tjuvajev JG, Chen SH, Joshi A, Joshi R, Guo ZS, Balatoni J, Ballon D, Koutcher J, Finn R, Woo SL, Blasberg RG.

Cancer Res. 1999 Oct 15;59(20):5186-93.

20.

Noninvasive quantitation of cytosine deaminase transgene expression in human tumor xenografts with in vivo magnetic resonance spectroscopy.

Stegman LD, Rehemtulla A, Beattie B, Kievit E, Lawrence TS, Blasberg RG, Tjuvajev JG, Ross BD.

Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9821-6.

21.

Herpes simplex virus thymidine kinase as a marker/reporter gene for PET imaging of gene therapy.

Blasberg RG, Tjuvajev JG.

Q J Nucl Med. 1999 Jun;43(2):163-9. Review.

PMID:
10429512
22.

Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography.

Tjuvajev JG, Avril N, Oku T, Sasajima T, Miyagawa T, Joshi R, Safer M, Beattie B, DiResta G, Daghighian F, Augensen F, Koutcher J, Zweit J, Humm J, Larson SM, Finn R, Blasberg R.

Cancer Res. 1998 Oct 1;58(19):4333-41.

24.

"Facilitated" amino acid transport is upregulated in brain tumors.

Miyagawa T, Oku T, Uehara H, Desai R, Beattie B, Tjuvajev J, Blasberg R.

J Cereb Blood Flow Metab. 1998 May;18(5):500-9.

PMID:
9591842
25.

Anti-neoplastic properties of human corticotropin releasing factor: involvement of the nitric oxide pathway.

Tjuvajev J, Kolesnikov Y, Joshi R, Sherinski J, Koutcher L, Zhou Y, Matei C, Koutcher J, Kreek MJ, Blasberg R.

In Vivo. 1998 Jan-Feb;12(1):1-10.

PMID:
9575420
26.
27.

Triumph over mischance: a role for nuclear medicine in gene therapy.

Larson SM, Tjuvajev J, Blasberg R.

J Nucl Med. 1997 Aug;38(8):1230-3. Review. No abstract available.

28.

Regression of C6 rat brain tumors by cells expressing an antisense insulin-like growth factor I receptor RNA.

Resnicoff M, Tjuvajev J, Rotman HL, Abraham D, Curtis M, Aiken R, Baserga R.

J Exp Ther Oncol. 1996 Nov;1(6):385-9.

PMID:
9414429
29.

Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy.

Tjuvajev JG, Finn R, Watanabe K, Joshi R, Oku T, Kennedy J, Beattie B, Koutcher J, Larson S, Blasberg RG.

Cancer Res. 1996 Sep 15;56(18):4087-95.

30.

Corticotropin-releasing factor decreases vasogenic brain edema.

Tjuvajev J, Uehara H, Desai R, Beattie B, Matei C, Zhou Y, Kreek MJ, Koutcher J, Blasberg R.

Cancer Res. 1996 Mar 15;56(6):1352-60.

31.

Imaging the expression of transfected genes in vivo.

Tjuvajev JG, Stockhammer G, Desai R, Uehara H, Watanabe K, Gansbacher B, Blasberg RG.

Cancer Res. 1995 Dec 15;55(24):6126-32.

32.

RG-2 glioma growth attenuation and severe brain edema caused by local production of interleukin-2 and interferon-gamma.

Tjuvajev J, Gansbacher B, Desai R, Beattie B, Kaplitt M, Matei C, Koutcher J, Gilboa E, Blasberg R.

Cancer Res. 1995 May 1;55(9):1902-10.

33.

Imaging of brain tumor proliferative activity with iodine-131-iododeoxyuridine.

Tjuvajev JG, Macapinlac HA, Daghighian F, Scott AM, Ginos JZ, Finn RD, Kothari P, Desai R, Zhang J, Beattie B, et al.

J Nucl Med. 1994 Sep;35(9):1407-17.

34.

Mutant herpes simplex virus induced regression of tumors growing in immunocompetent rats.

Kaplitt MG, Tjuvajev JG, Leib DA, Berk J, Pettigrew KD, Posner JB, Pfaff DW, Rabkin SD, Blasberg RG.

J Neurooncol. 1994;19(2):137-47.

PMID:
7964989
35.

Iododeoxyuridine uptake and retention as a measure of tumor growth.

Tjuvajev J, Muraki A, Ginos J, Berk J, Koutcher J, Ballon D, Beattie B, Finn R, Dahighian F, Blasberg R.

J Nucl Med. 1993 Jul;34(7):1152-62. Erratum in: J Nucl Med 1993 Oct;34(10):1645.

36.
37.

Correlations between brain oedema volume on CT and CSF dynamics in severely head injured patients.

Tjuvajev J, Eelmäe J, Kuklane M, Tomberg T, Tikk A.

Acta Neurochir Suppl (Wien). 1990;51:305-7.

PMID:
2089923

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