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Items: 28

1.

Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9.

Ason B, Tep S, Davis HR Jr, Xu Y, Tetzloff G, Galinski B, Soriano F, Dubinina N, Zhu L, Stefanni A, Wong KK, Tadin-Strapps M, Bartz SR, Hubbard B, Ranalletta M, Sachs AB, Flanagan WM, Strack A, Kuklin NA.

J Lipid Res. 2011 Apr;52(4):679-87. doi: 10.1194/jlr.M013664. Epub 2011 Jan 24.

2.

Gender-dependent effect of Gpbar1 genetic deletion on the metabolic profiles of diet-induced obese mice.

Vassileva G, Hu W, Hoos L, Tetzloff G, Yang S, Liu L, Kang L, Davis HR, Hedrick JA, Lan H, Kowalski T, Gustafson EL.

J Endocrinol. 2010 Jun;205(3):225-32. doi: 10.1677/JOE-10-0009. Epub 2010 Mar 30.

3.

Lack of FFAR1/GPR40 does not protect mice from high-fat diet-induced metabolic disease.

Lan H, Hoos LM, Liu L, Tetzloff G, Hu W, Abbondanzo SJ, Vassileva G, Gustafson EL, Hedrick JA, Davis HR.

Diabetes. 2008 Nov;57(11):2999-3006. doi: 10.2337/db08-0596. Epub 2008 Aug 4.

4.

Cholesterol homeostasis by the intestine: lessons from Niemann-Pick C1 Like 1 [NPC1L1).

Davis HR Jr, Basso F, Hoos LM, Tetzloff G, Lally SM, Altmann SW.

Atheroscler Suppl. 2008 Sep;9(2):77-81. doi: 10.1016/j.atherosclerosissup.2008.05.008. Epub 2008 Jun 27. Review.

PMID:
18585981
5.

Ezetimibe improves high fat and cholesterol diet-induced non-alcoholic fatty liver disease in mice.

Zheng S, Hoos L, Cook J, Tetzloff G, Davis H Jr, van Heek M, Hwa JJ.

Eur J Pharmacol. 2008 Apr 14;584(1):118-24. doi: 10.1016/j.ejphar.2008.01.045. Epub 2008 Feb 12.

PMID:
18329014
6.

Deficiency of Niemann-Pick C1 Like 1 prevents atherosclerosis in ApoE-/- mice.

Davis HR Jr, Hoos LM, Tetzloff G, Maguire M, Zhu LJ, Graziano MP, Altmann SW.

Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):841-9. Epub 2007 Jan 11.

7.

Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation.

Vassileva G, Golovko A, Markowitz L, Abbondanzo SJ, Zeng M, Yang S, Hoos L, Tetzloff G, Levitan D, Murgolo NJ, Keane K, Davis HR Jr, Hedrick J, Gustafson EL.

Biochem J. 2006 Sep 15;398(3):423-30.

8.

Transgenic overexpression of neuromedin U promotes leanness and hypophagia in mice.

Kowalski TJ, Spar BD, Markowitz L, Maguire M, Golovko A, Yang S, Farley C, Cook JA, Tetzloff G, Hoos L, Del Vecchio RA, Kazdoba TM, McCool MF, Hwa JJ, Hyde LA, Davis H, Vassileva G, Hedrick JA, Gustafson EL.

J Endocrinol. 2005 Apr;185(1):151-64.

9.

Characterization of the putative native and recombinant rat sterol transporter Niemann-Pick C1 Like 1 (NPC1L1) protein.

Iyer SP, Yao X, Crona JH, Hoos LM, Tetzloff G, Davis HR Jr, Graziano MP, Altmann SW.

Biochim Biophys Acta. 2005 Apr 15;1722(3):282-92.

PMID:
15777641
10.

Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis.

Davis HR Jr, Zhu LJ, Hoos LM, Tetzloff G, Maguire M, Liu J, Yao X, Iyer SP, Lam MH, Lund EG, Detmers PA, Graziano MP, Altmann SW.

J Biol Chem. 2004 Aug 6;279(32):33586-92. Epub 2004 Jun 1.

11.

Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption.

Altmann SW, Davis HR Jr, Zhu LJ, Yao X, Hoos LM, Tetzloff G, Iyer SP, Maguire M, Golovko A, Zeng M, Wang L, Murgolo N, Graziano MP.

Science. 2004 Feb 20;303(5661):1201-4.

12.

The identification of intestinal scavenger receptor class B, type I (SR-BI) by expression cloning and its role in cholesterol absorption.

Altmann SW, Davis HR Jr, Yao X, Laverty M, Compton DS, Zhu LJ, Crona JH, Caplen MA, Hoos LM, Tetzloff G, Priestley T, Burnett DA, Strader CD, Graziano MP.

Biochim Biophys Acta. 2002 Jan 30;1580(1):77-93.

PMID:
11923102
13.

Ezetimibe, a potent cholesterol absorption inhibitor, inhibits the development of atherosclerosis in ApoE knockout mice.

Davis HR Jr, Compton DS, Hoos L, Tetzloff G.

Arterioscler Thromb Vasc Biol. 2001 Dec;21(12):2032-8.

14.

Ezetimibe, a potent cholesterol absorption inhibitor, normalizes combined dyslipidemia in obese hyperinsulinemic hamsters.

van Heek M, Austin TM, Farley C, Cook JA, Tetzloff GG, Davis HR.

Diabetes. 2001 Jun;50(6):1330-5.

15.

Disparate effects of thrombin receptor activating peptide on platelets and peripheral vasculature in rats.

Chintala MS, Chiu PJ, Bernadino V, Tetzloff GG, Tedesco R, Sabin C, Watkins RW, Sybertz EJ.

Eur J Pharmacol. 1998 May 22;349(2-3):237-43.

PMID:
9671103
16.

Inhibition of platelet adhesion and aggregation by E4021, a type V phosphodiesterase inhibitor, in guinea pigs.

Chiu PJ, Vemulapalli S, Chintala M, Kurowski S, Tetzloff GG, Brown AD, Sybertz EJ.

Naunyn Schmiedebergs Arch Pharmacol. 1997 Apr;355(4):463-9.

PMID:
9109362
17.

Characterization of in vitro and in vivo platelet responses to thrombin and thrombin receptor-activating peptides in guinea pigs.

Chiu PJ, Tetzloff GG, Foster C, Chintala M, Sybertz EJ.

Eur J Pharmacol. 1997 Feb 19;321(1):129-35.

PMID:
9083795
18.
19.

Influence of C-ANF receptor and neutral endopeptidase on pharmacokinetics of ANF in rats.

Chiu PJ, Tetzloff G, Romano MT, Foster CJ, Sybertz EJ.

Am J Physiol. 1991 Jan;260(1 Pt 2):R208-16.

PMID:
1847022
20.

Effects of BRL 34915, a putative K channel opener, on transmembrane 45Ca movements in rabbit aortic smooth muscle.

Chiu PJ, Tetzloff G, Ahn HS, Sybertz EJ.

Eur J Pharmacol. 1988 Oct 18;155(3):229-37.

PMID:
3234486
21.

Phorbol 12,13-dibutyrate, an activator of protein kinase C, stimulates both contraction and Ca2+ fluxes in dog saphenous vein.

Chiu PJ, Tetzloff G, Chatterjee M, Sybertz EJ.

Naunyn Schmiedebergs Arch Pharmacol. 1988 Aug;338(2):114-20.

PMID:
3185741
22.

Comparative effects of vinpocetine and 8-Br-cyclic GMP on the contraction and 45Ca-fluxes in the rabbit aorta.

Chiu PJ, Tetzloff G, Ahn HS, Sybertz EJ.

Am J Hypertens. 1988 Jul;1(3 Pt 1):262-8.

PMID:
2455529
23.

Phorbol dibutyrate contractions in rabbit aorta: calcium dependence and sensitivity to nitrovasodilators and 8-BR-cyclic GMP.

Sybertz EJ, Desiderio DM, Tetzloff G, Chiu PJ.

J Pharmacol Exp Ther. 1986 Oct;239(1):78-83.

PMID:
3093673
24.

A post-calcium site of action for HA1004, a novel vasculorelaxant.

Chiu PJ, Tetzloff G, Sybertz EJ.

Life Sci. 1986 Jul 21;39(3):255-61.

PMID:
3736325
25.

The effects of atriopeptin II on calcium fluxes in rabbit aorta.

Chiu PJ, Tetzloff G, Sybertz EJ.

Eur J Pharmacol. 1986 May 27;124(3):277-84.

PMID:
2426119
26.
27.

Gastric antisecretory properties of SCH 32651.

Chiu PJ, Barnett A, Tetzloff G, Kaminski J.

Arch Int Pharmacodyn Ther. 1984 Jul;270(1):116-27.

PMID:
6238577
28.

Studies on the mechanisms of the antisecretory and cytoprotective actions of SCH 28080.

Chiu PJ, Casciano C, Tetzloff G, Long JF, Barnett A.

J Pharmacol Exp Ther. 1983 Jul;226(1):121-5.

PMID:
6306218

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