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Items: 1 to 50 of 151

1.

The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis.

Fusella F, Seclì L, Busso E, Krepelova A, Moiso E, Rocca S, Conti L, Annaratone L, Rubinetto C, Mello-Grand M, Singh V, Chiorino G, Silengo L, Altruda F, Turco E, Morotti A, Oliviero S, Castellano I, Cavallo F, Provero P, Tarone G, Brancaccio M.

Nat Commun. 2017 Nov 21;8(1):1636. doi: 10.1038/s41467-017-01829-1.

2.

Morgana acts as an oncosuppressor in chronic myeloid leukemia.

Di Savino A, Panuzzo C, Rocca S, Familiari U, Piazza R, Crivellaro S, Carrà G, Ferretti R, Fusella F, Giugliano E, Camporeale A, Franco I, Miniscalco B, Cutrin JC, Turco E, Silengo L, Hirsch E, Rege-Cambrin G, Gambacorti-Passerini C, Pandolfi PP, Papotti M, Saglio G, Tarone G, Morotti A, Brancaccio M.

Blood. 2015 Apr 2;125(14):2245-53. doi: 10.1182/blood-2014-05-575001. Epub 2015 Feb 12.

3.

The muscle-specific chaperone protein melusin is a potent cardioprotective agent.

Tarone G, Brancaccio M.

Basic Res Cardiol. 2015 Mar;110(2):10. doi: 10.1007/s00395-015-0466-9. Epub 2015 Feb 5. Review.

4.

Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.

Seano G, Chiaverina G, Gagliardi PA, di Blasio L, Puliafito A, Bouvard C, Sessa R, Tarone G, Sorokin L, Helley D, Jain RK, Serini G, Bussolino F, Primo L.

Nat Cell Biol. 2014 Oct;16(10):931-41, 1-8. doi: 10.1038/ncb3036. Epub 2014 Sep 14.

5.

Overexpression of the muscle-specific protein, melusin, protects from cardiac ischemia/reperfusion injury.

Penna C, Brancaccio M, Tullio F, Rubinetto C, Perrelli MG, Angotti C, Pagliaro P, Tarone G.

Basic Res Cardiol. 2014 Jul;109(4):418. doi: 10.1007/s00395-014-0418-9. Epub 2014 May 25.

6.

Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology.

Tarone G, Balligand JL, Bauersachs J, Clerk A, De Windt L, Heymans S, Hilfiker-Kleiner D, Hirsch E, Iaccarino G, Knöll R, Leite-Moreira AF, Lourenço AP, Mayr M, Thum T, Tocchetti CG.

Eur J Heart Fail. 2014 May;16(5):494-508. doi: 10.1002/ejhf.62. Epub 2014 Mar 17. Review.

7.

Morgana acts as a proto-oncogene through inhibition of a ROCK-PTEN pathway.

Fusella F, Ferretti R, Recupero D, Rocca S, Di Savino A, Tornillo G, Silengo L, Turco E, Cabodi S, Provero P, Pandolfi PP, Sapino A, Tarone G, Brancaccio M.

J Pathol. 2014 Oct;234(2):152-63. doi: 10.1002/path.4341. Epub 2014 Aug 6.

PMID:
24615293
8.

Keep your heart in shape: molecular chaperone networks for treating heart disease.

Tarone G, Brancaccio M.

Cardiovasc Res. 2014 Jun 1;102(3):346-61. doi: 10.1093/cvr/cvu049. Epub 2014 Feb 28. Review.

PMID:
24585203
9.

ESC Working Group on Myocardial Function Position Paper: how to study the right ventricle in experimental models.

Leite-Moreira AF, Lourenço AP, Balligand JL, Bauersachs J, Clerk A, De Windt LJ, Heymans S, Hilfiker-Kleiner D, Hirsch E, Iaccarino G, Kaminski KA, Knöll R, Mayr M, Tarone G, Thum T, Tocchetti CG.

Eur J Heart Fail. 2014 May;16(5):509-18. doi: 10.1002/ejhf.66. Epub 2014 Feb 23. Review.

10.

Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research.

Hohl M, Ardehali H, Azuaje FJ, Breckenridge RA, Doehner W, Eaton P, Ehret GB, Fujita T, Gaetani R, Giacca M, Hasenfuß G, Heymans S, Leite-Moreira AF, Linke WA, Linz D, Lyon A, Mamas MA, Orešič M, Papp Z, Pedrazzini T, Piepoli M, Prosser B, Rizzuto R, Tarone G, Tian R, van Craenenbroeck E, van Rooij E, Wai T, Weiss G, Maack C.

Eur J Heart Fail. 2014 Jan;16(1):6-14. doi: 10.1002/ejhf.10. Epub 2013 Dec 14. Review. No abstract available.

11.

Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction.

Unsöld B, Kaul A, Sbroggiò M, Schubert C, Regitz-Zagrosek V, Brancaccio M, Damilano F, Hirsch E, Van Bilsen M, Munts C, Sipido K, Bito V, Detre E, Wagner NM, Schäfer K, Seidler T, Vogt J, Neef S, Bleckmann A, Maier LS, Balligand JL, Bouzin C, Ventura-Clapier R, Garnier A, Eschenhagen T, El-Armouche A, Knöll R, Tarone G, Hasenfuß G.

Cardiovasc Res. 2014 Jan 1;101(1):97-107. doi: 10.1093/cvr/cvt235. Epub 2013 Oct 15.

12.

Interaction of the heart and its close and distant neighbours: report of the Meeting of the ESC Working Groups Myocardial Function and Cellular Biology.

Hirsch E, Hilfiker-Kleiner D, Balligand JL, Tarone G, De Windt L, Bauersachs J, Ferdinandy P, Davidson S, Hausenloy DJ, Schulz R.

Cardiovasc Res. 2013 Sep 1;99(4):595-9. doi: 10.1093/cvr/cvt179. Epub 2013 Jul 16. No abstract available.

PMID:
23860811
13.

Key role of ERK1/2 molecular scaffolds in heart pathology.

Tarone G, Sbroggiò M, Brancaccio M.

Cell Mol Life Sci. 2013 Nov;70(21):4047-54. doi: 10.1007/s00018-013-1321-5. Epub 2013 Mar 27. Review.

PMID:
23532408
14.

Extracellular matrix, integrins, and growth factors as tailors of the stem cell niche.

Brizzi MF, Tarone G, Defilippi P.

Curr Opin Cell Biol. 2012 Oct;24(5):645-51. doi: 10.1016/j.ceb.2012.07.001. Epub 2012 Aug 13. Review.

PMID:
22898530
15.

Morgana and melusin: two fairies chaperoning signal transduction.

Ferretti R, Sbroggiò M, Di Savino A, Fusella F, Bertero A, Michowski W, Tarone G, Brancaccio M.

Cell Cycle. 2011 Nov 1;10(21):3678-83. doi: 10.4161/cc.10.21.18202. Epub 2011 Nov 1. Review.

PMID:
22037254
16.

ERK1/2 activation in heart is controlled by melusin, focal adhesion kinase and the scaffold protein IQGAP1.

Sbroggiò M, Bertero A, Velasco S, Fusella F, De Blasio E, Bahou WF, Silengo L, Turco E, Brancaccio M, Tarone G.

J Cell Sci. 2011 Oct 15;124(Pt 20):3515-24. doi: 10.1242/jcs.091140.

17.

Towards a re-definition of 'cardiac hypertrophy' through a rational characterization of left ventricular phenotypes: a position paper of the Working Group 'Myocardial Function' of the ESC.

Knöll R, Iaccarino G, Tarone G, Hilfiker-Kleiner D, Bauersachs J, Leite-Moreira AF, Sugden PH, Balligand JL; European Society of Cardiology.

Eur J Heart Fail. 2011 Aug;13(8):811-9. doi: 10.1093/eurjhf/hfr071. Epub 2011 Jun 27.

18.

IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload.

Sbroggiò M, Carnevale D, Bertero A, Cifelli G, De Blasio E, Mascio G, Hirsch E, Bahou WF, Turco E, Silengo L, Brancaccio M, Lembo G, Tarone G.

Cardiovasc Res. 2011 Aug 1;91(3):456-64. doi: 10.1093/cvr/cvr103. Epub 2011 Apr 14.

19.

p130Cas is an essential transducer element in ErbB2 transformation.

Cabodi S, Tinnirello A, Bisaro B, Tornillo G, del Pilar Camacho-Leal M, Forni G, Cojoca R, Iezzi M, Amici A, Montani M, Eva A, Di Stefano P, Muthuswamy SK, Tarone G, Turco E, Defilippi P.

FASEB J. 2010 Oct;24(10):3796-808. doi: 10.1096/fj.10-157347. Epub 2010 May 26.

PMID:
20505116
20.

Morgana/CHP-1 is a novel chaperone able to protect cells from stress.

Michowski W, Ferretti R, Wisniewska MB, Ambrozkiewicz M, Beresewicz M, Fusella F, Skibinska-Kijek A, Zablocka B, Brancaccio M, Tarone G, Kuznicki J.

Biochim Biophys Acta. 2010 Sep;1803(9):1043-9. doi: 10.1016/j.bbamcr.2010.05.005. Epub 2010 May 20.

21.

Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis.

Ferretti R, Palumbo V, Di Savino A, Velasco S, Sbroggiò M, Sportoletti P, Micale L, Turco E, Silengo L, Palumbo G, Hirsch E, Teruya-Feldstein J, Bonaccorsi S, Pandolfi PP, Gatti M, Tarone G, Brancaccio M.

Dev Cell. 2010 Mar 16;18(3):486-95. doi: 10.1016/j.devcel.2009.12.020.

22.

Melusin gene (ITGB1BP2) nucleotide variations study in hypertensive and cardiopathic patients.

Palumbo V, Segat L, Padovan L, Amoroso A, Trimarco B, Izzo R, Lembo G, Regitz-Zagrosek V, Knoll R, Brancaccio M, Tarone G, Crovella S.

BMC Med Genet. 2009 Dec 17;10:140. doi: 10.1186/1471-2350-10-140.

23.

Convergence of integrins and EGF receptor signaling via PI3K/Akt/FoxO pathway in early gene Egr-1 expression.

Cabodi S, Morello V, Masi A, Cicchi R, Broggio C, Distefano P, Brunelli E, Silengo L, Pavone F, Arcangeli A, Turco E, Tarone G, Moro L, Defilippi P.

J Cell Physiol. 2009 Feb;218(2):294-303. doi: 10.1002/jcp.21603.

PMID:
18844239
24.

The mammalian CHORD-containing protein melusin is a stress response protein interacting with Hsp90 and Sgt1.

Sbroggiò M, Ferretti R, Percivalle E, Gutkowska M, Zylicz A, Michowski W, Kuznicki J, Accornero F, Pacchioni B, Lanfranchi G, Hamm J, Turco E, Silengo L, Tarone G, Brancaccio M.

FEBS Lett. 2008 Jun 11;582(13):1788-94. doi: 10.1016/j.febslet.2008.04.058. Epub 2008 May 12.

25.

Laminin-binding integrin alpha7 is required for contractile phenotype expression by human airway myocytes.

Tran T, Ens-Blackie K, Rector ES, Stelmack GL, McNeill KD, Tarone G, Gerthoffer WT, Unruh H, Halayko AJ.

Am J Respir Cell Mol Biol. 2007 Dec;37(6):668-80. Epub 2007 Jul 19.

26.

Alternative BCR/ABL splice variants in Philadelphia chromosome-positive leukemias result in novel tumor-specific fusion proteins that may represent potential targets for immunotherapy approaches.

Volpe G, Cignetti A, Panuzzo C, Kuka M, Vitaggio K, Brancaccio M, Perrone G, Rinaldi M, Prato G, Fava M, Geuna M, Pautasso M, Casnici C, Signori E, Tonon G, Tarone G, Marelli O, Fazio VM, Saglio G.

Cancer Res. 2007 Jun 1;67(11):5300-7.

27.

p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity.

Di Stefano P, Damiano L, Cabodi S, Aramu S, Tordella L, Praduroux A, Piva R, Cavallo F, Forni G, Silengo L, Tarone G, Turco E, Defilippi P.

EMBO J. 2007 Jun 20;26(12):2843-55. Epub 2007 May 24.

28.

Quantitation of multisite EGF receptor phosphorylation using mass spectrometry and a novel normalization approach.

Boeri Erba E, Matthiesen R, Bunkenborg J, Schulze WX, Di Stefano P, Cabodi S, Tarone G, Defilippi P, Jensen ON.

J Proteome Res. 2007 Jul;6(7):2768-85. Epub 2007 May 25.

PMID:
17523611
29.

Altered melusin expression in the hearts of aortic stenosis patients.

Brokat S, Thomas J, Herda LR, Knosalla C, Pregla R, Brancaccio M, Accornero F, Tarone G, Hetzer R, Regitz-Zagrosek V.

Eur J Heart Fail. 2007 Jun-Jul;9(6-7):568-73. Epub 2007 Apr 30.

30.

Sarcoglycan subcomplex expression in normal human smooth muscle.

Anastasi G, Cutroneo G, Sidoti A, Rinaldi C, Bruschetta D, Rizzo G, D'Angelo R, Tarone G, Amato A, Favaloro A.

J Histochem Cytochem. 2007 Aug;55(8):831-43. Epub 2007 Apr 16.

PMID:
17438352
31.

Quantification of the expression level of integrin receptor alpha(v)beta3 in cell lines and MR imaging with antibody-coated iron oxide particles.

Benedetto S, Pulito R, Crich SG, Tarone G, Aime S, Silengo L, Hamm J.

Magn Reson Med. 2006 Oct;56(4):711-6.

32.

p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.

Cabodi S, Tinnirello A, Di Stefano P, Bisarò B, Ambrosino E, Castellano I, Sapino A, Arisio R, Cavallo F, Forni G, Glukhova M, Silengo L, Altruda F, Turco E, Tarone G, Defilippi P.

Cancer Res. 2006 May 1;66(9):4672-80.

33.

Integrin signalling: the tug-of-war in heart hypertrophy.

Brancaccio M, Hirsch E, Notte A, Selvetella G, Lembo G, Tarone G.

Cardiovasc Res. 2006 Jun 1;70(3):422-33. Epub 2006 Feb 8. Review. Erratum in: Cardiovasc Res. 2006 Dec 1;72(3):494.

PMID:
16466704
34.

Selective Rac-1 inhibition protects from diabetes-induced vascular injury.

Vecchione C, Aretini A, Marino G, Bettarini U, Poulet R, Maffei A, Sbroggiò M, Pastore L, Gentile MT, Notte A, Iorio L, Hirsch E, Tarone G, Lembo G.

Circ Res. 2006 Feb 3;98(2):218-25. Epub 2005 Dec 15.

35.

p130Cas mediates the transforming properties of the anaplastic lymphoma kinase.

Ambrogio C, Voena C, Manazza AD, Piva R, Riera L, Barberis L, Costa C, Tarone G, Defilippi P, Hirsch E, Boeri Erba E, Mohammed S, Jensen ON, Palestro G, Inghirami G, Chiarle R.

Blood. 2005 Dec 1;106(12):3907-16. Epub 2005 Aug 16. Erratum in: Blood. 2009 Sep 24;114(13):2851.

36.

Systematic analysis of the epidermal growth factor receptor by mass spectrometry reveals stimulation-dependent multisite phosphorylation.

Boeri Erba E, Bergatto E, Cabodi S, Silengo L, Tarone G, Defilippi P, Jensen ON.

Mol Cell Proteomics. 2005 Aug;4(8):1107-21. Epub 2005 May 18.

37.

Cardiac overexpression of melusin protects from dilated cardiomyopathy due to long-standing pressure overload.

De Acetis M, Notte A, Accornero F, Selvetella G, Brancaccio M, Vecchione C, Sbroggiò M, Collino F, Pacchioni B, Lanfranchi G, Aretini A, Ferretti R, Maffei A, Altruda F, Silengo L, Tarone G, Lembo G.

Circ Res. 2005 May 27;96(10):1087-94. Epub 2005 Apr 28. Erratum in: Circ Res. 2005 Jul 8;97(1):e5.

38.

Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma.

Vecchione C, Patrucco E, Marino G, Barberis L, Poulet R, Aretini A, Maffei A, Gentile MT, Storto M, Azzolino O, Brancaccio M, Colussi GL, Bettarini U, Altruda F, Silengo L, Tarone G, Wymann MP, Hirsch E, Lembo G.

J Exp Med. 2005 Apr 18;201(8):1217-28. Epub 2005 Apr 11.

39.

{beta}1 Integrin and IL-3R coordinately regulate STAT5 activation and anchorage-dependent proliferation.

Defilippi P, Rosso A, Dentelli P, Calvi C, Garbarino G, Tarone G, Pegoraro L, Brizzi MF.

J Cell Biol. 2005 Mar 28;168(7):1099-108.

40.

Magnetic resonance imaging visualization of targeted cells by the internalization of supramolecular adducts formed between avidin and biotinylated Gd3+ chelates.

Geninatti Crich S, Barge A, Battistini E, Cabella C, Coluccia S, Longo D, Mainero V, Tarone G, Aime S.

J Biol Inorg Chem. 2005 Jan;10(1):78-86. Epub 2004 Dec 23.

PMID:
15616832
41.

Adaptive and maladaptive hypertrophic pathways: points of convergence and divergence.

Selvetella G, Hirsch E, Notte A, Tarone G, Lembo G.

Cardiovasc Res. 2004 Aug 15;63(3):373-80. Review.

PMID:
15276462
42.

Integrin regulation of epidermal growth factor (EGF) receptor and of EGF-dependent responses.

Cabodi S, Moro L, Bergatto E, Boeri Erba E, Di Stefano P, Turco E, Tarone G, Defilippi P.

Biochem Soc Trans. 2004 Jun;32(Pt3):438-42. Review.

PMID:
15157155
43.

p130Cas interacts with estrogen receptor alpha and modulates non-genomic estrogen signaling in breast cancer cells.

Cabodi S, Moro L, Baj G, Smeriglio M, Di Stefano P, Gippone S, Surico N, Silengo L, Turco E, Tarone G, Defilippi P.

J Cell Sci. 2004 Mar 15;117(Pt 8):1603-11.

44.

Identification of Krit1B: a novel alternative splicing isoform of cerebral cavernous malformation gene-1.

Retta SF, Avolio M, Francalanci F, Procida S, Balzac F, Degani S, Tarone G, Silengo L.

Gene. 2004 Jan 21;325:63-78.

PMID:
14697511
45.

Distribution and localization of vinculin-talin-integrin system and dystrophin-glycoprotein complex in human skeletal muscle. Immunohistochemical study using confocal laser scanning microscopy.

Anastasi G, Amato A, Tarone G, Vita G, Monici MC, Magaudda L, Brancaccio M, Sidoti A, Trimarchi F, Favaloro A, Cutroneo G.

Cells Tissues Organs. 2003;175(3):151-64.

PMID:
14663158
46.

P130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading.

Di Stefano P, Cabodi S, Boeri Erba E, Margaria V, Bergatto E, Giuffrida MG, Silengo L, Tarone G, Turco E, Defilippi P.

Mol Biol Cell. 2004 Feb;15(2):787-800. Epub 2003 Dec 2.

47.

Positional control of cell fate through joint integrin/receptor protein kinase signaling.

Giancotti FG, Tarone G.

Annu Rev Cell Dev Biol. 2003;19:173-206. Review.

PMID:
14570568
48.

Molecular interplay between mechanical and humoral signalling in cardiac hypertrophy.

Tarone G, Lembo G.

Trends Mol Med. 2003 Sep;9(9):376-82. Review.

PMID:
13129703
49.

Chp-1 and melusin, two CHORD containing proteins in vertebrates.

Brancaccio M, Menini N, Bongioanni D, Ferretti R, De Acetis M, Silengo L, Tarone G.

FEBS Lett. 2003 Sep 11;551(1-3):47-52.

50.

Altered expression of integrins in RSV-transformed chick epiphyseal chondrocytes.

Arcucci A, Alaia V, Montagnani S, Pontarelli G, Retta SF, Tarone G, Gionti E.

Biochimie. 2003 May;85(5):483-92.

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