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Items: 1 to 50 of 290

1.

TL1A blocking ameliorates intestinal fibrosis in the T cell transfer model of chronic colitis in mice.

Li H, Song J, Niu G, Zhang H, Guo J, Shih DQ, Targan SR, Zhang X.

Pathol Res Pract. 2018 Feb;214(2):217-227. doi: 10.1016/j.prp.2017.11.017. Epub 2017 Nov 26.

PMID:
29254800
2.

Serologic, Genetic, and Clinical Associations with Increased Healthcare Resource Utilization in Inflammatory Bowel Disease.

Gu P, Kapur A, Li D, Haritunians T, Vasiliauskas E, Shih DQ, Targan SR, Spiegel BMR, McGovern DPB, Black JT, Melmed GY.

J Dig Dis. 2017 Dec 18. doi: 10.1111/1751-2980.12566. [Epub ahead of print]

PMID:
29251413
3.

Colonic Phenotypes Are Associated with Poorer Response to Anti-TNF Therapies in Patients with IBD.

Yoon SM, Haritunians T, Chhina S, Liu Z, Yang S, Landers C, Li D, Ye BD, Shih D, Vasiliauskas EA, Ippoliti A, Rabizadeh S, Targan SR, Melmed GY, McGovern DPB.

Inflamm Bowel Dis. 2017 Aug;23(8):1382-1393. doi: 10.1097/MIB.0000000000001150.

PMID:
28590340
4.

Association of Ribonuclease T2 Gene Polymorphisms With Decreased Expression and Clinical Characteristics of Severity in Crohn's Disease.

Gonsky R, Fleshner P, Deem RL, Biener-Ramanujan E, Li D, Potdar AA, Bilsborough J, Yang S, McGovern DPB, Targan SR.

Gastroenterology. 2017 Jul;153(1):219-232. doi: 10.1053/j.gastro.2017.04.002. Epub 2017 Apr 9.

PMID:
28400196
5.

Myeloid ATG16L1 Facilitates Host-Bacteria Interactions in Maintaining Intestinal Homeostasis.

Zhang H, Zheng L, McGovern DP, Hamill AM, Ichikawa R, Kanazawa Y, Luu J, Kumagai K, Cilluffo M, Fukata M, Targan SR, Underhill DM, Zhang X, Shih DQ.

J Immunol. 2017 Mar 1;198(5):2133-2146. doi: 10.4049/jimmunol.1601293. Epub 2017 Jan 27.

PMID:
28130498
6.

Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis.

Tschurtschenthaler M, Adolph TE, Ashcroft JW, Niederreiter L, Bharti R, Saveljeva S, Bhattacharyya J, Flak MB, Shih DQ, Fuhler GM, Parkes M, Kohno K, Iwawaki T, Janneke van der Woude C, Harding HP, Smith AM, Peppelenbosch MP, Targan SR, Ron D, Rosenstiel P, Blumberg RS, Kaser A.

J Exp Med. 2017 Feb;214(2):401-422. doi: 10.1084/jem.20160791. Epub 2017 Jan 12.

7.

A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of Brodalumab in Patients With Moderate-to-Severe Crohn's Disease.

Targan SR, Feagan B, Vermeire S, Panaccione R, Melmed GY, Landers C, Li D, Russell C, Newmark R, Zhang N, Chon Y, Hsu YH, Lin SL, Klekotka P.

Am J Gastroenterol. 2016 Nov;111(11):1599-1607. doi: 10.1038/ajg.2016.298. Epub 2016 Aug 2.

PMID:
27481309
8.

The TNF family member TL1A induces IL-22 secretion in committed human Th17 cells via IL-9 induction.

Thomas LS, Targan SR, Tsuda M, Yu QT, Salumbides BC, Haritunians T, Mengesha E, McGovern DP, Michelsen KS.

J Leukoc Biol. 2017 Mar;101(3):727-737. doi: 10.1189/jlb.3A0316-129R. Epub 2016 Oct 12.

PMID:
27733581
9.

Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease.

Brant SR, Okou DT, Simpson CL, Cutler DJ, Haritunians T, Bradfield JP, Chopra P, Prince J, Begum F, Kumar A, Huang C, Venkateswaran S, Datta LW, Wei Z, Thomas K, Herrinton LJ, Klapproth JA, Quiros AJ, Seminerio J, Liu Z, Alexander JS, Baldassano RN, Dudley-Brown S, Cross RK, Dassopoulos T, Denson LA, Dhere TA, Dryden GW, Hanson JS, Hou JK, Hussain SZ, Hyams JS, Isaacs KL, Kader H, Kappelman MD, Katz J, Kellermayer R, Kirschner BS, Kuemmerle JF, Kwon JH, Lazarev M, Li E, Mack D, Mannon P, Moulton DE, Newberry RD, Osuntokun BO, Patel AS, Saeed SA, Targan SR, Valentine JF, Wang MH, Zonca M, Rioux JD, Duerr RH, Silverberg MS, Cho JH, Hakonarson H, Zwick ME, McGovern DP, Kugathasan S.

Gastroenterology. 2017 Jan;152(1):206-217.e2. doi: 10.1053/j.gastro.2016.09.032. Epub 2016 Sep 28.

10.

Cytokine and anti-cytokine therapies in prevention or treatment of fibrosis in IBD.

Jacob N, Targan SR, Shih DQ.

United European Gastroenterol J. 2016 Aug;4(4):531-40. doi: 10.1177/2050640616649356. Epub 2016 May 10. Review.

11.

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Jonsdottir I, Thorsteinsdottir U, Degenhardt F, Mucha S, Kurki MI, Li D, D'Amato M, Annese V, Vermeire S, Weersma RK, Halfvarson J, Paavola-Sakki P, Lappalainen M, Lek M, Cummings B, Tukiainen T, Haritunians T, Halme L, Koskinen LL, Ananthakrishnan AN, Luo Y, Heap GA, Visschedijk MC; UK IBD Genetics Consortium; NIDDK IBD Genetics Consortium, MacArthur DG, Neale BM, Ahmad T, Anderson CA, Brant SR, Duerr RH, Silverberg MS, Cho JH, Palotie A, Saavalainen P, Kontula K, Färkkilä M, McGovern DP, Franke A, Stefansson K, Rioux JD, Xavier RJ, Daly MJ, Barrett J, de Lane K, Edwards C, Hart A, Hawkey C, Jostins L, Kennedy N, Lamb C, Lee J, Lees C, Mansfield J, Mathew C, Mowatt C, Newman B, Nimmo E, Parkes M, Pollard M, Prescott N, Randall J, Rice D, Satsangi J, Simmons A, Tremelling M, Uhlig H, Wilson D, Abraham C, Achkar JP, Bitton A, Boucher G, Croitoru K, Fleshner P, Glas J, Kugathasan S, Limbergen JV, Milgrom R, Proctor D, Regueiro M, Schumm PL, Sharma Y, Stempak JM, Targan SR, Wang MH.

Nat Commun. 2016 Aug 9;7:12342. doi: 10.1038/ncomms12342.

12.

A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition.

Li D, Achkar JP, Haritunians T, Jacobs JP, Hui KY, D'Amato M, Brand S, Radford-Smith G, Halfvarson J, Niess JH, Kugathasan S, Büning C, Schumm LP, Klei L, Ananthakrishnan A, Aumais G, Baidoo L, Dubinsky M, Fiocchi C, Glas J, Milgrom R, Proctor DD, Regueiro M, Simms LA, Stempak JM, Targan SR, Törkvist L, Sharma Y, Devlin B, Borneman J, Hakonarson H, Xavier RJ, Daly M, Brant SR, Rioux JD, Silverberg MS, Cho JH, Braun J, McGovern DP, Duerr RH.

Gastroenterology. 2016 Oct;151(4):724-32. doi: 10.1053/j.gastro.2016.06.051. Epub 2016 Aug 1.

13.

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease.

Chu H, Khosravi A, Kusumawardhani IP, Kwon AH, Vasconcelos AC, Cunha LD, Mayer AE, Shen Y, Wu WL, Kambal A, Targan SR, Xavier RJ, Ernst PB, Green DR, McGovern DP, Virgin HW, Mazmanian SK.

Science. 2016 May 27;352(6289):1116-20. doi: 10.1126/science.aad9948. Epub 2016 May 5.

14.

Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor.

Hoang-Yen Tran D, Hoang-Ngoc Tran D, Mattai SA, Sallam T, Ortiz C, Lee EC, Robbins L, Ho S, Lee JE, Fisseha E, Shieh C, Sideri A, Shih DQ, Fleshner P, McGovern DP, Vu M, Hing TC, Bakirtzi K, Cheng M, Su B, Law I, Karagiannides I, Targan SR, Gallo RL, Li Z, Koon HW.

Int J Obes (Lond). 2016 Sep;40(9):1424-34. doi: 10.1038/ijo.2016.90. Epub 2016 May 10.

15.

TNFRSF1B Is Associated with ANCA in IBD.

Li D, Silverberg MS, Haritunians T, Dubinsky MC, Landers C, Stempak JM, Milgrom R, Guo X, Chen YD, Rotter JI, Taylor KD, McGovern DP, Targan SR.

Inflamm Bowel Dis. 2016 Jun;22(6):1346-52. doi: 10.1097/MIB.0000000000000771.

PMID:
27104820
16.

Clinical Factors Associated with the Development of Crohn's Disease in Inflammatory Bowel Disease-unclassified Patients Undergoing Ileal Pouch-anal Anastomosis.

Koh SZ, Zaghiyan KN, Li Q, Rabizadeh S, Melmed GY, Targan SR, Fleshner PR.

Inflamm Bowel Dis. 2016 Jun;22(6):1397-402. doi: 10.1097/MIB.0000000000000744.

PMID:
26978722
17.

Perianal Crohn's Disease is Associated with Distal Colonic Disease, Stricturing Disease Behavior, IBD-Associated Serologies and Genetic Variation in the JAK-STAT Pathway.

Kaur M, Panikkath D, Yan X, Liu Z, Berel D, Li D, Vasiliauskas EA, Ippoliti A, Dubinsky M, Shih DQ, Melmed GY, Haritunians T, Fleshner P, Targan SR, McGovern DP.

Inflamm Bowel Dis. 2016 Apr;22(4):862-9. doi: 10.1097/MIB.0000000000000705.

18.

Differential Levels of Tl1a Affect the Expansion and Function of Regulatory T Cells in Modulating Murine Colitis.

Sidhu-Varma M, Shih DQ, Targan SR.

Inflamm Bowel Dis. 2016 Mar;22(3):548-59. doi: 10.1097/MIB.0000000000000653.

19.

A validated web-based tool to display individualised Crohn's disease predicted outcomes based on clinical, serologic and genetic variables.

Siegel CA, Horton H, Siegel LS, Thompson KD, Mackenzie T, Stewart SK, Rice PW, Stempak JM, Dezfoli S, Haritunians T, Levy A, Baek M, Milgrom R, Dulai PS, Targan SR, Silverberg MS, Dubinsky MC, McGovern DP.

Aliment Pharmacol Ther. 2016 Jan;43(2):262-71. doi: 10.1111/apt.13460. Epub 2015 Nov 15.

20.

Ocular Manifestations in Inflammatory Bowel Disease Are Associated with Other Extra-intestinal Manifestations, Gender, and Genes Implicated in Other Immune-related Traits.

Taleban S, Li D, Targan SR, Ippoliti A, Brant SR, Cho JH, Duerr RH, Rioux JD, Silverberg MS, Vasiliauskas EA, Rotter JI, Haritunians T, Shih DQ, Dubinsky M, Melmed GY, McGovern DP.

J Crohns Colitis. 2016 Jan;10(1):43-9. doi: 10.1093/ecco-jcc/jjv178. Epub 2015 Oct 8.

PMID:
26449790
21.

Colectomy with Permanent End Ileostomy Is More Cost-Effective than Ileal Pouch-Anal Anastomosis for Crohn's Colitis.

Taleban S, Van Oijen MG, Vasiliauskas EA, Fleshner PR, Shen B, Ippoliti AF, Targan SR, Melmed GY.

Dig Dis Sci. 2016 Feb;61(2):550-9. doi: 10.1007/s10620-015-3886-3. Epub 2015 Oct 5.

PMID:
26434930
22.

Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans.

Huang C, Haritunians T, Okou DT, Cutler DJ, Zwick ME, Taylor KD, Datta LW, Maranville JC, Liu Z, Ellis S, Chopra P, Alexander JS, Baldassano RN, Cross RK, Dassopoulos T, Dhere TA, Duerr RH, Hanson JS, Hou JK, Hussain SZ, Isaacs KL, Kachelries KE, Kader H, Kappelman MD, Katz J, Kellermayer R, Kirschner BS, Kuemmerle JF, Kumar A, Kwon JH, Lazarev M, Mannon P, Moulton DE, Osuntokun BO, Patel A, Rioux JD, Rotter JI, Saeed S, Scherl EJ, Silverberg MS, Silverman A, Targan SR, Valentine JF, Wang MH, Simpson CL, Bridges SL, Kimberly RP, Rich SS, Cho JH, Rienzo AD, Kao LWH, McGovern DPB, Brant SR, Kugathasan S.

Gastroenterology. 2015 Nov;149(6):1575-1586. doi: 10.1053/j.gastro.2015.07.065. Epub 2015 Aug 14.

23.

Combined Immunosuppression Impairs Immunogenicity to Tetanus and Pertussis Vaccination Among Patients with Inflammatory Bowel Disease.

Dezfoli S, Horton HA, Thepyasuwan N, Berel D, Targan SR, Vasiliauskas EA, Dubinsky M, Shih DQ, Kaur M, McGovern DP, Ippoliti A, Feldman EJ, Melmed GY.

Inflamm Bowel Dis. 2015 Aug;21(8):1754-60. doi: 10.1097/MIB.0000000000000448.

PMID:
25985242
24.

Long-term outcomes of thalidomide in refractory Crohn's disease.

Gerich ME, Yoon JL, Targan SR, Ippoliti AF, Vasiliauskas EA.

Aliment Pharmacol Ther. 2015 Mar;41(5):429-37. doi: 10.1111/apt.13057. Epub 2014 Dec 15.

25.

Reliable generation of induced pluripotent stem cells from human lymphoblastoid cell lines.

Barrett R, Ornelas L, Yeager N, Mandefro B, Sahabian A, Lenaeus L, Targan SR, Svendsen CN, Sareen D.

Stem Cells Transl Med. 2014 Dec;3(12):1429-34. doi: 10.5966/sctm.2014-0121. Epub 2014 Oct 8.

26.

Human intestinal epithelial cells express interleukin-10 through Toll-like receptor 4-mediated epithelial-macrophage crosstalk.

Hyun J, Romero L, Riveron R, Flores C, Kanagavelu S, Chung KD, Alonso A, Sotolongo J, Ruiz J, Manukyan A, Chun S, Singh G, Salas P, Targan SR, Fukata M.

J Innate Immun. 2015;7(1):87-101. doi: 10.1159/000365417. Epub 2014 Aug 20.

27.

IFNG rs1861494 polymorphism is associated with IBD disease severity and functional changes in both IFNG methylation and protein secretion.

Gonsky R, Deem RL, Landers CJ, Haritunians T, Yang S, Targan SR.

Inflamm Bowel Dis. 2014 Oct;20(10):1794-801. doi: 10.1097/MIB.0000000000000172.

28.

Microbiota activation and regulation of innate and adaptive immunity.

Alexander KL, Targan SR, Elson CO 3rd.

Immunol Rev. 2014 Jul;260(1):206-20. doi: 10.1111/imr.12180. Review.

29.

Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function.

Lin L, Ma C, Wei B, Aziz N, Rajalingam R, Yusung S, Erlich HA, Trachtenberg EA, Targan SR, McGovern DP, Heath JR, Braun J.

J Immunol. 2014 Jul 15;193(2):940-9. doi: 10.4049/jimmunol.1400093. Epub 2014 Jun 16.

30.

Antibiotics for Treatment of Clostridium difficile Infection in Hospitalized Patients with Inflammatory Bowel Disease.

Horton HA, Dezfoli S, Berel D, Hirsch J, Ippoliti A, McGovern D, Kaur M, Shih D, Dubinsky M, Targan SR, Fleshner P, Vasiliauskas EA, Grein J, Murthy R, Melmed GY.

Antimicrob Agents Chemother. 2014 Sep;58(9):5054-9. doi: 10.1128/AAC.02606-13. Epub 2014 Jun 9.

31.

Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis.

Shih DQ, Zheng L, Zhang X, Zhang H, Kanazawa Y, Ichikawa R, Wallace KL, Chen J, Pothoulakis C, Koon HW, Targan SR.

Mucosal Immunol. 2014 Nov;7(6):1492-503. doi: 10.1038/mi.2014.37. Epub 2014 May 21.

32.

Clinical, serologic, and genetic factors associated with pyoderma gangrenosum and erythema nodosum in inflammatory bowel disease patients.

Weizman A, Huang B, Berel D, Targan SR, Dubinsky M, Fleshner P, Ippoliti A, Kaur M, Panikkath D, Brant S, Oikonomou I, Duerr R, Rioux J, Silverberg M, Rotter JI, Vasiliauskas E, Haritunians T, Shih D, Li D, Melmed GY, McGovern DP.

Inflamm Bowel Dis. 2014 Mar;20(3):525-33. doi: 10.1097/01.MIB.0000442011.60285.68.

33.

Weeding out the facts: the reality about cannabis and Crohn's disease.

Vu MP, Melmed GY, Targan SR.

Clin Gastroenterol Hepatol. 2014 May;12(5):898-9. doi: 10.1016/j.cgh.2013.11.016. Epub 2013 Nov 20. No abstract available.

PMID:
24269921
34.

Erratum: Sustained TL1A (TNFSF15) expression on both lymphoid and myeloid cells leads to mild spontaneous intestinal inflammation and fibrosis (DOI: 10.1556/EuJMI.3.2013.1.2).

Zheng L, Zhang X, Chen J, Ichikawa R, Wallace K, Pothoulakis C, Koon HW, Targan SR, Shih DQ.

Eur J Microbiol Immunol (Bp). 2013 Jun;3(2):141. doi: 10.1556/EuJMI.3.2013.2.8. Epub 2013 Jun 5. No abstract available.

35.

Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease.

VanDussen KL, Liu TC, Li D, Towfic F, Modiano N, Winter R, Haritunians T, Taylor KD, Dhall D, Targan SR, Xavier RJ, McGovern DP, Stappenbeck TS.

Gastroenterology. 2014 Jan;146(1):200-9. doi: 10.1053/j.gastro.2013.09.048. Epub 2013 Sep 25.

36.

Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease.

Dubinsky MC, Kugathasan S, Kwon S, Haritunians T, Wrobel I, Wahbeh G, Quiros A, Bahar R, Silber G, Farrior S, Stephens M, Teleten N, Panikkath D, Ippoliti A, Vasiliauskas E, Fleshner P, Williams C, Landers C, Rotter JI, Targan SR, Taylor KD, McGovern DP.

Inflamm Bowel Dis. 2013 Jul;19(8):1662-70. doi: 10.1097/MIB.0b013e318281f275.

37.

Multiple activating and repressive cis-promoter regions regulate TNFSF15 expression in human primary mononuclear cells.

Gonsky R, Deem RL, Targan SR.

Cytokine. 2013 Jul;63(1):36-42. doi: 10.1016/j.cyto.2013.04.004. Epub 2013 Apr 30.

38.

SUSTAINED TL1A (TNFSF15) EXPRESSION ON BOTH LYMPHOID AND MYELOID CELLS LEADS TO MILD SPONTANEOUS INTESTINAL INFLAMMATION AND FIBROSIS.

Zheng L, Zhang X, Chen J, Ichikawa R, Wallace K, Pothoulakis C, Koon HW, Targan SR, Shih DQ.

Eur J Microbiol Immunol (Bp). 2013 Mar;3(1):11-20.

39.

Human monoclonal antibodies against Clostridium difficile toxins A and B inhibit inflammatory and histologic responses to the toxins in human colon and peripheral blood monocytes.

Koon HW, Shih DQ, Hing TC, Yoo JH, Ho S, Chen X, Kelly CP, Targan SR, Pothoulakis C.

Antimicrob Agents Chemother. 2013 Jul;57(7):3214-23. doi: 10.1128/AAC.02633-12. Epub 2013 Apr 29.

40.

HMPL-004 (Andrographis paniculata extract) prevents development of murine colitis by inhibiting T-cell proliferation and TH1/TH17 responses.

Michelsen KS, Wong MH, Ko B, Thomas LS, Dhall D, Targan SR.

Inflamm Bowel Dis. 2013 Jan;19(1):151-64. doi: 10.1002/ibd.22983.

41.

Assessing health status in inflammatory bowel disease using a novel single-item numeric rating scale.

Surti B, Spiegel B, Ippoliti A, Vasiliauskas EA, Simpson P, Shih DQ, Targan SR, McGovern DP, Melmed GY.

Dig Dis Sci. 2013 May;58(5):1313-21. doi: 10.1007/s10620-012-2500-1. Epub 2012 Dec 19.

42.

Ulcerative colitis: steroid-refractory ulcerative colitis-ciclosporin or infliximab?

Kaur M, Targan SR.

Nat Rev Gastroenterol Hepatol. 2013 Jan;10(1):8-9. doi: 10.1038/nrgastro.2012.235. Epub 2012 Dec 11. No abstract available.

PMID:
23229328
43.

Markers of intestinal inflammation in patients with ankylosing spondylitis: a pilot study.

Matzkies FG, Targan SR, Berel D, Landers CJ, Reveille JD, McGovern DP, Weisman MH.

Arthritis Res Ther. 2012 Nov 29;14(6):R261. doi: 10.1186/ar4106.

44.

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, Büning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H; International IBD Genetics Consortium (IIBDGC), Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC, Cho JH.

Nature. 2012 Nov 1;491(7422):119-24. doi: 10.1038/nature11582.

45.

Andrographis paniculata extract (HMPL-004) for active ulcerative colitis.

Sandborn WJ, Targan SR, Byers VS, Rutty DA, Mu H, Zhang X, Tang T.

Am J Gastroenterol. 2013 Jan;108(1):90-8. doi: 10.1038/ajg.2012.340. Epub 2012 Oct 9.

46.

Split-dose administration of thiopurine drugs: a novel and effective strategy for managing preferential 6-MMP metabolism.

Shih DQ, Nguyen M, Zheng L, Ibanez P, Mei L, Kwan LY, Bradford K, Ting C, Targan SR, Vasiliauskas EA.

Aliment Pharmacol Ther. 2012 Sep;36(5):449-58. doi: 10.1111/j.1365-2036.2012.05206.x. Epub 2012 Jul 11.

47.

The antimicrobial peptide cathelicidin modulates Clostridium difficile-associated colitis and toxin A-mediated enteritis in mice.

Hing TC, Ho S, Shih DQ, Ichikawa R, Cheng M, Chen J, Chen X, Law I, Najarian R, Kelly CP, Gallo RL, Targan SR, Pothoulakis C, Koon HW.

Gut. 2013 Sep;62(9):1295-305. doi: 10.1136/gutjnl-2012-302180. Epub 2012 Jul 3.

48.

Abatacept for Crohn's disease and ulcerative colitis.

Sandborn WJ, Colombel JF, Sands BE, Rutgeerts P, Targan SR, Panaccione R, Bressler B, Geboes K, Schreiber S, Aranda R, Gujrathi S, Luo A, Peng Y, Salter-Cid L, Hanauer SB.

Gastroenterology. 2012 Jul;143(1):62-69.e4. doi: 10.1053/j.gastro.2012.04.010. Epub 2012 Apr 12.

PMID:
22504093
49.

Colorectal cancer screening and surveillance in Crohn's colitis.

Basseri RJ, Basseri B, Vassilaki ME, Melmed GY, Ippoliti A, Vasiliauskas EA, Fleshner PR, Lechago J, Hu B, Berel D, Targan SR, Papadakis KA.

J Crohns Colitis. 2012 Sep;6(8):824-9. doi: 10.1016/j.crohns.2012.01.005. Epub 2012 Feb 5.

PMID:
22398087
50.

CD161 DEFINES EFFECTOR T CELLS THAT EXPRESS LIGHT AND RESPOND TO TL1A-DR3 SIGNALING.

Cohavy O, Shih DQ, Doherty TM, Ware CF, Targan SR.

Eur J Microbiol Immunol (Bp). 2011 Mar;1(1):70-79.

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