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Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2+ Breast Cancer.

Yu X, Ghamande S, Liu H, Xue L, Zhao S, Tan W, Zhao L, Tang SC, Wu D, Korkaya H, Maihle NJ, Liu HY.

Mol Ther Nucleic Acids. 2018 Mar 2;10:317-330. doi: 10.1016/j.omtn.2017.12.015. Epub 2017 Dec 30.


Glomerular Filtration Rates in Asians.

Teo BW, Zhang L, Guh JY, Tang SCW, Jha V, Kang DH, Tanchanco R, Hooi LS, Praditpornsilpa K, Kong X, Zuo L, Chan GC, Lee EJC.

Adv Chronic Kidney Dis. 2018 Jan;25(1):41-48. doi: 10.1053/j.ackd.2017.10.005. Review.


Berberine induces miR-373 expression in hepatocytes to inactivate hepatic steatosis associated AKT-S6 kinase pathway.

Li CH, Tang SC, Wong CH, Wang Y, Jiang JD, Chen Y.

Eur J Pharmacol. 2018 Feb 22;825:107-118. doi: 10.1016/j.ejphar.2018.02.035. [Epub ahead of print]


Isolated Basilar Artery Dissection with Ischemic Stroke: Report of 4 Cases.

Chen SJ, Tsai LK, Tang SC, Jeng JS.

Acta Neurol Taiwan. 2017 Sep 15;26(3):138-143.


Transcriptome Analysis Reveals Intermittent Fasting-Induced Genetic Changes in Ischemic Stroke.

Kim J, Kang SW, Mallilankaraman K, Baik SH, Lim JC, Balaganapathy P, She DT, Lok KZ, Fann DY, Thambiayah U, Tang SC, Stranahan AM, Dheen ST, Gelderblom M, Seet RC, Karamyan VT, Vemuganti R, Sobey CG, Mattson MP, Jo DG, Arumugam TV.

Hum Mol Genet. 2018 Feb 13. doi: 10.1093/hmg/ddy057. [Epub ahead of print]


Non-invasive assessment of kidney allograft fibrosis with shear wave elastography: A radiological-pathological correlation analysis.

Ma MK, Law HK, Tse KS, Chan KW, Chan GC, Yap DY, Mok MM, Kwan LP, Tang SC, Choy BY, Chan TM.

Int J Urol. 2018 Feb 14. doi: 10.1111/iju.13536. [Epub ahead of print]


Retrospective observational cohort study on cosmetic outcome of using Ti-Ni memory alloy wire for intradermal suture following mastectomy in patients with breast cancer.

Li G, Qin S, Sun X, Wang J, Zhang Y, Zhang J, Zhang J, Tang SC, Ren H.

Oncol Lett. 2018 Feb;15(2):2465-2470. doi: 10.3892/ol.2017.7603. Epub 2017 Dec 13.


[Biomonitoring application in the exposome assessment].

Hu GP, Chen ZJ, Tang SC, Jia G.

Zhonghua Yu Fang Yi Xue Za Zhi. 2018 Feb 6;52(2):201-205. doi: 10.3760/cma.j.issn.0253-9624.2018.02.017. Chinese.


Gout: A Disease of Kings.

Tang SCW.

Contrib Nephrol. 2018;192:77-81. doi: 10.1159/000484281. Epub 2018 Jan 23.


Breast cancer stem-like cells are sensitized to tamoxifen induction of self-renewal inhibition with enforced Let-7c dependent on Wnt blocking.

Sun X, Xu C, Xiao G, Meng J, Wang J, Tang SC, Qin S, Du N, Li G, Ren H, Liu D.

Int J Mol Med. 2018 Apr;41(4):1967-1975. doi: 10.3892/ijmm.2018.3388. Epub 2018 Jan 15.


Cytokine MIF Enhances Blood-Brain Barrier Permeability: Impact for Therapy in Ischemic Stroke.

Liu YC, Tsai YH, Tang SC, Liou HC, Kang KH, Liou HH, Jeng JS, Fu WM.

Sci Rep. 2018 Jan 15;8(1):743. doi: 10.1038/s41598-017-16927-9.


Association between leukoaraiosis and cerebral blood flow territory alteration in asymptomatic internal carotid artery stenosis.

Chen YF, Kuo YS, Wu WC, Tang SC, Jiang SF.

Clin Radiol. 2018 Jan 9. pii: S0009-9260(17)30571-8. doi: 10.1016/j.crad.2017.12.006. [Epub ahead of print]


Complement C5a inhibition moderates lipid metabolism and reduces tubulointerstitial fibrosis in diabetic nephropathy.

Yiu WH, Li RX, Wong DWL, Wu HJ, Chan KW, Chan LYY, Leung JCK, Lai KN, Sacks SH, Zhou W, Tang SCW.

Nephrol Dial Transplant. 2017 Dec 26. doi: 10.1093/ndt/gfx336. [Epub ahead of print]


SGLT2 inhibitor empagliflozin: finally at the latter stage of understanding?

Chan GCW, Tang SCW.

Kidney Int. 2018 Jan;93(1):22-24. doi: 10.1016/j.kint.2017.07.008.


Human induced pluripotent stem cell-derived mesenchymal stem cells prevent adriamycin nephropathy in mice.

Wu HJ, Yiu WH, Wong DWL, Li RX, Chan LYY, Leung JCK, Zhang Y, Lian Q, Lai KN, Tse HF, Tang SCW.

Oncotarget. 2017 Oct 10;8(61):103640-103656. doi: 10.18632/oncotarget.21760. eCollection 2017 Nov 28.


MiR-129 blocks estrogen induction of NOTCH signaling activity in breast cancer stem-like cells.

Xiao G, Li X, Li G, Zhang B, Xu C, Qin S, Du N, Wang J, Tang SC, Zhang J, Ren H, Chen K, Sun X.

Oncotarget. 2017 Sep 21;8(61):103261-103273. doi: 10.18632/oncotarget.21143. eCollection 2017 Nov 28.


Rapid Progression of Vertebral Artery Occlusion After Radiotherapy for Nasopharyngeal Carcinoma.

Chen TC, Tang SC, Jeng JS.

Acta Neurol Taiwan. 2017 Jun 15;26(2):76-77. No abstract available.


Clinical Application of Detecting 21-Gene Recurrence Score in Predicating Prognosis and Therapy Response of Patients with Breast Cancer from Two Medical Centers.

Xiao G, Meng J, Zhang J, Li G, Du N, Qin S, Wang J, Xu C, Ren H, Tang SC, Sun X.

Cancer Invest. 2017 Nov 26;35(10):639-646. doi: 10.1080/07357907.2017.1405015.


Posttransplant lymphoproliferative disorders in kidney transplant recipients: a retrospective cohort analysis over two decades in Hong Kong.

Cheung CY, Ma MKM, Chau KF, Chak WL, Tang SCW.

Oncotarget. 2017 Jun 30;8(57):96903-96912. doi: 10.18632/oncotarget.18890. eCollection 2017 Nov 14.


Color Doppler ultrasonography as an alternative tool for postoperative evaluation of collaterals after indirect revascularization surgery in Moyamoya disease.

Yeh SJ, Tang SC, Tsai LK, Lee CW, Chen YF, Liu HM, Yang SH, Kuo MF, Jeng JS.

PLoS One. 2017 Dec 8;12(12):e0188948. doi: 10.1371/journal.pone.0188948. eCollection 2017. Erratum in: PLoS One. 2018 Jan 11;13(1):e0191381.


Toll-Like Receptor 4, but Not Neutrophil Extracellular Traps, Promote IFN Type I Expression to Enhance Th2 Responses to Nippostrongylus brasiliensis.

Pellefigues C, Tang SC, Schmidt A, White RF, Lamiable O, Connor LM, Ruedl C, Dobrucki J, Le Gros G, Ronchese F.

Front Immunol. 2017 Nov 16;8:1575. doi: 10.3389/fimmu.2017.01575. eCollection 2017.


The effect and associated factors of dispatcher recognition of stroke: A retrospective observational study.

Hsieh MJ, Chien KL, Sun JT, Tang SC, Tsai LK, Chiang WC, Chien YC, Jeng JS, Huei-Ming Ma M; Taipei EMS Stroke Collaborative Group.

J Formos Med Assoc. 2017 Nov 17. pii: S0929-6646(17)30650-2. doi: 10.1016/j.jfma.2017.10.008. [Epub ahead of print]


Relatives in silent kidney disease screening (RISKS) study: A Chinese cohort study.

Li PK, Ng JK, Cheng YL, Kwan TH, Leung CB, Lau MF, Choi KS, Fung SK, Ho YW, Mak SK, Tang SC, Wong KS, Yong D, Lui SL; Hong Kong Society of Nephrology.

Nephrology (Carlton). 2017 Dec;22 Suppl 4:35-42. doi: 10.1111/nep.13148.


Elevated Plasma Level of Soluble Form of RAGE in Ischemic Stroke Patients with Dementia.

Tang SC, Yang KC, Hu CJ, Chiou HY, Wu CC, Jeng JS.

Neuromolecular Med. 2017 Dec;19(4):579-583. doi: 10.1007/s12017-017-8471-9. Epub 2017 Nov 2.


Endovascular thrombectomy for acute ischemic stroke: A single-center experience in Taiwan.

Chu HJ, Tang SC, Lee CW, Jeng JS, Liu HM.

J Formos Med Assoc. 2017 Oct 31. pii: S0929-6646(17)30048-7. doi: 10.1016/j.jfma.2017.09.016. [Epub ahead of print]


Atrial fibrillation trial to evaluate real-world procedures for their utility in helping to lower stroke events (AFTER-PULSE): Study protocol for a randomized controlled trial.

Hsieh TT, Lee M, Huang WY, Tang SC, Sung SF, Chang KH, Lee JD, Lee TH, Huang YS, Jeng JS, Chung CM, Wu YL, Ovbiagele B.

Contemp Clin Trials Commun. 2017 Jun;6:127-130. doi: 10.1016/j.conctc.2017.04.005. Epub 2017 Apr 26.


Effects of dl-3-n-butylphthalide on serum VEGF and bFGF levels in acute cerebral infarction.

Tang SC, Luo CJ, Zhang KH, Li K, Fan XH, Ning LP, Xue P.

Eur Rev Med Pharmacol Sci. 2017 Oct;21(19):4431-4436.


Not all immune-checkpoint inhibitors are created equal: Meta-analysis and systematic review of immune-related adverse events in cancer trials.

El Osta B, Hu F, Sadek R, Chintalapally R, Tang SC.

Crit Rev Oncol Hematol. 2017 Nov;119:1-12. doi: 10.1016/j.critrevonc.2017.09.002. Epub 2017 Sep 8. Review.


Ficus virens proanthocyanidins induced apoptosis in breast cancer cells concomitantly ameliorated 5-fluorouracil induced intestinal mucositis in rats.

Chen XX, Lam KH, Chen QX, Leung GP, Tang SCW, Sze SC, Xiao JB, Feng F, Wang Y, Zhang KY, Zhang ZJ.

Food Chem Toxicol. 2017 Dec;110:49-61. doi: 10.1016/j.fct.2017.10.017. Epub 2017 Oct 10.


Genotype 4 hepatitis E virus is a cause of chronic hepatitis in renal transplant recipients in Hong Kong.

Sridhar S, Chan JFW, Yap DYH, Teng JLL, Huang C, Yip CCY, Hung IFN, Tang SCW, Lau SKP, Woo PCY, Yuen KY.

J Viral Hepat. 2018 Feb;25(2):209-213. doi: 10.1111/jvh.12799. Epub 2017 Nov 13. No abstract available.


Analysis of risk factors for post-operative complications and prognostic predictors of disease recurrence following definitive treatment of patients with esophageal cancer from two medical centers in Northwest China.

Wang J, Zhang B, Meng J, Xiao G, Li X, Li G, Qin S, Du N, Zhang J, Zhang J, Xu C, Tang SC, Liang R, Ren H, Sun X.

Exp Ther Med. 2017 Sep;14(3):2584-2594. doi: 10.3892/etm.2017.4835. Epub 2017 Jul 25.


miR-367 stimulates Wnt cascade activation through degrading FBXW7 in NSCLC stem cells.

Xiao G, Zhang B, Meng J, Wang J, Xu C, Tang SC, Li X, Zhang J, Liang R, Ren H, Sun X.

Cell Cycle. 2017;16(24):2374-2385. doi: 10.1080/15384101.2017.1380136. Epub 2017 Nov 14.


Cancer risk in patients with diabetic nephropathy: A retrospective cohort study in Hong Kong.

Cheung CY, Ma MKM, Chak WL, Tang SCW.

Medicine (Baltimore). 2017 Sep;96(38):e8077. doi: 10.1097/MD.0000000000008077.


Augmented expression of polo-like kinase 1 indicates poor clinical outcome for breast patients: a systematic review and meta-analysis.

Zhang Y, Wu Z, Liu D, Wang M, Xiao G, Wang P, Sun X, Ren H, Tang SC, Du N.

Oncotarget. 2017 Apr 20;8(34):57723-57732. doi: 10.18632/oncotarget.17301. eCollection 2017 Aug 22. Review.


Nano Let‑7b sensitization of eliminating esophageal cancer stem‑like cells is dependent on blockade of Wnt activation of symmetric division.

Pang Y, Liu J, Li X, Zhang Y, Zhang B, Zhang J, Du N, Xu C, Liang R, Ren H, Tang SC, Sun X.

Int J Oncol. 2017 Oct;51(4):1077-1088. doi: 10.3892/ijo.2017.4104. Epub 2017 Aug 29.


Pancreatic neuro-insular network in young mice revealed by 3D panoramic histology.

Tang SC, Shen CN, Lin PY, Peng SJ, Chien HJ, Chou YH, Chamberlain CE, Pasricha PJ.

Diabetologia. 2018 Jan;61(1):158-167. doi: 10.1007/s00125-017-4408-y. Epub 2017 Sep 1.


Human pancreatic neuro-insular network in health and fatty infiltration.

Tang SC, Baeyens L, Shen CN, Peng SJ, Chien HJ, Scheel DW, Chamberlain CE, German MS.

Diabetologia. 2018 Jan;61(1):168-181. doi: 10.1007/s00125-017-4409-x. Epub 2017 Aug 29.


Analytical performance of reagent for assaying tau protein in human plasma and feasibility study screening neurodegenerative diseases.

Yang SY, Chiu MJ, Chen TF, Lin CH, Jeng JS, Tang SC, Lee YF, Yang CC, Liu BH, Chen HH, Wu CC.

Sci Rep. 2017 Aug 24;7(1):9304. doi: 10.1038/s41598-017-09009-3.


Utilization of Statins Beyond the Initial Period After Stroke and 1-Year Risk of Recurrent Stroke.

Lee M, Saver JL, Wu YL, Tang SC, Lee JD, Rao NM, Wang HH, Jeng JS, Lee TH, Chen PC, Ovbiagele B.

J Am Heart Assoc. 2017 Aug 2;6(8). pii: e005658. doi: 10.1161/JAHA.117.005658.


Low Pulse Pressure After Acute Ischemic Stroke is Associated With Unfavorable Outcomes: The Taiwan Stroke Registry.

Tang SC, Yin JH, Liu CH, Sun MH, Lee JT, Sun Y, Hsu CS, Sun MC, Lin CH, Chen CH, Lien LM, Muo CH, Jeng JS, Hsu CY; Taiwan Stroke Registry Investigators.

J Am Heart Assoc. 2017 Jun 22;6(6). pii: e005113. doi: 10.1161/JAHA.116.005113.


Annual direct medical costs associated with diabetes-related complications in the event year and in subsequent years in Hong Kong.

Jiao F, Wong CKH, Tang SCW, Fung CSC, Tan KCB, McGhee S, Gangwani R, Lam CLK.

Diabet Med. 2017 Sep;34(9):1276-1283. doi: 10.1111/dme.13416. Epub 2017 Jul 12.


Acute thyroiditis: An under-recognized complication of parathyroidectomy in end-stage renal failure patients with secondary hyperparathyroidism.

Chan GC, Lee PC, Kwan LP, Yip TP, Tang SC.

Nephrology (Carlton). 2017 Jul;22(7):572. doi: 10.1111/nep.12825. No abstract available.


[Treatment of glottic cancer involving the anterior commissure by transoral CO(2) laser surgery].

Li JJ, Zhang JL, He FY, Tang SC, Zhu ZF, Chen WX.

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 May 7;52(5):337-342. doi: 10.3760/cma.j.issn.1673-0860.2017.05.004. Chinese.


Effect of Kidney Dysfunction on Cerebral Cortical Thinning in Elderly Population.

Chen CH, Chen YF, Chiu MJ, Chen TF, Tsai PH, Chen JH, Yen CJ, Tang SC, Yeh SJ, Chen YC.

Sci Rep. 2017 May 24;7(1):2337. doi: 10.1038/s41598-017-02537-y.


Alterations of cerebral perfusion in asymptomatic internal carotid artery steno-occlusive disease.

Chen YF, Tang SC, Wu WC, Kao HL, Kuo YS, Yang SC.

Sci Rep. 2017 May 12;7(1):1841. doi: 10.1038/s41598-017-02094-4.


[Research and suggestion on occupational exposure limits of titanium dioxide nanoparticles in workplaces].

Zhao L, Zheng YX, Kong FL, Zhang J, Tang SC, Zhang YF, Li XZ, Zhou JW, Chen ZJ, Xu HD, Jia G.

Zhonghua Yu Fang Yi Xue Za Zhi. 2017 May 6;51(5):381-385. doi: 10.3760/cma.j.issn.0253-9624.2017.05.003. Chinese. No abstract available.


Using precursor ion scan of 184 with liquid chromatography-electrospray ionization-tandem mass spectrometry for concentration normalization in cellular lipidomic studies.

Chao HC, Chen GY, Hsu LC, Liao HW, Yang SY, Wang SY, Li YL, Tang SC, Tseng YJ, Kuo CH.

Anal Chim Acta. 2017 Jun 8;971:68-77. doi: 10.1016/j.aca.2017.03.033. Epub 2017 Mar 27.


Mycobacterium chlorophenolicum: An uncommon cause of peritonitis in a peritoneal dialysis patient.

Chan GCW, Mok MMY, Hung DLL, Chan JFW, Kwan LPY, Ma MKM, Yap DYH, Tang SCW.

Nephrology (Carlton). 2017 Jun;22(6):498-499. doi: 10.1111/nep.12820. No abstract available.


Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis.

Kulkarni S, Micci MA, Leser J, Shin C, Tang SC, Fu YY, Liu L, Li Q, Saha M, Li C, Enikolopov G, Becker L, Rakhilin N, Anderson M, Shen X, Dong X, Butte MJ, Song H, Southard-Smith EM, Kapur RP, Bogunovic M, Pasricha PJ.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):E3709-E3718. doi: 10.1073/pnas.1619406114. Epub 2017 Apr 18.

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