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Items: 1 to 50 of 204

1.

Bleogens: Cactus-Derived Anti-Candida Cysteine-Rich Peptides with Three Different Precursor Arrangements.

Loo S, Kam A, Xiao T, Tam JP.

Front Plant Sci. 2017 Dec 22;8:2162. doi: 10.3389/fpls.2017.02162. eCollection 2017.

2.

β-Ginkgotides: Hyperdisulfide-constrained peptides from Ginkgo biloba.

Wong KH, Tan WL, Xiao T, Tam JP.

Sci Rep. 2017 Jul 21;7(1):6140. doi: 10.1038/s41598-017-06598-x.

3.

Lybatides from Lycium barbarum Contain An Unusual Cystine-stapled Helical Peptide Scaffold.

Tan WL, Wong KH, Lei J, Sakai N, Tan HW, Hilgenfeld R, Tam JP.

Sci Rep. 2017 Jul 12;7(1):5194. doi: 10.1038/s41598-017-05037-1.

4.

Vaccatides: Antifungal Glutamine-Rich Hevein-Like Peptides from Vaccaria hispanica.

Wong KH, Tan WL, Kini SG, Xiao T, Serra A, Sze SK, Tam JP.

Front Plant Sci. 2017 Jun 21;8:1100. doi: 10.3389/fpls.2017.01100. eCollection 2017.

5.

Enzymatic Engineering of Live Bacterial Cell Surfaces Using Butelase 1.

Bi X, Yin J, Nguyen GKT, Rao C, Halim NBA, Hemu X, Tam JP, Liu CF.

Angew Chem Int Ed Engl. 2017 Jun 26;56(27):7822-7825. doi: 10.1002/anie.201703317. Epub 2017 Jun 9.

PMID:
28524544
6.

Morintides: cargo-free chitin-binding peptides from Moringa oleifera.

Kini SG, Wong KH, Tan WL, Xiao T, Tam JP.

BMC Plant Biol. 2017 Mar 31;17(1):68. doi: 10.1186/s12870-017-1014-6.

7.

Macrocyclic Antimicrobial Peptides Engineered from ω-Conotoxin.

Hemu X, Tam JP.

Curr Pharm Des. 2017;23(14):2131-2138. doi: 10.2174/1381612822666161027120518.

8.

Engineering a Catalytically Efficient Recombinant Protein Ligase.

Yang R, Wong YH, Nguyen GKT, Tam JP, Lescar J, Wu B.

J Am Chem Soc. 2017 Apr 19;139(15):5351-5358. doi: 10.1021/jacs.6b12637. Epub 2017 Mar 1.

PMID:
28199119
9.

Dietary phytochemical PEITC restricts tumor development via modulation of epigenetic writers and erasers.

Park JE, Sun Y, Lim SK, Tam JP, Dekker M, Chen H, Sze SK.

Sci Rep. 2017 Jan 12;7:40569. doi: 10.1038/srep40569.

10.

Identification and Characterization of Roseltide, a Knottin-type Neutrophil Elastase Inhibitor Derived from Hibiscus sabdariffa.

Loo S, Kam A, Xiao T, Nguyen GK, Liu CF, Tam JP.

Sci Rep. 2016 Dec 19;6:39401. doi: 10.1038/srep39401.

11.

An Orally Active Bradykinin B1 Receptor Antagonist Engineered as a Bifunctional Chimera of Sunflower Trypsin Inhibitor.

Qiu Y, Taichi M, Wei N, Yang H, Luo KQ, Tam JP.

J Med Chem. 2017 Jan 12;60(1):504-510. doi: 10.1021/acs.jmedchem.6b01011. Epub 2016 Dec 15.

PMID:
27977181
12.

Ginkgotides: Proline-Rich Hevein-Like Peptides from Gymnosperm Ginkgo biloba.

Wong KH, Tan WL, Serra A, Xiao T, Sze SK, Yang D, Tam JP.

Front Plant Sci. 2016 Nov 3;7:1639. eCollection 2016.

13.

Butelase-Mediated Ligation as an Efficient Bioconjugation Method for the Synthesis of Peptide Dendrimers.

Cao Y, Nguyen GK, Chuah S, Tam JP, Liu CF.

Bioconjug Chem. 2016 Nov 16;27(11):2592-2596. Epub 2016 Oct 18.

PMID:
27723303
14.

Butelase-mediated cyclization and ligation of peptides and proteins.

Nguyen GK, Qiu Y, Cao Y, Hemu X, Liu CF, Tam JP.

Nat Protoc. 2016 Oct;11(10):1977-1988. doi: 10.1038/nprot.2016.118. Epub 2016 Sep 22.

PMID:
27658013
15.

Butelase-Mediated Macrocyclization of d-Amino-Acid-Containing Peptides.

Nguyen GK, Hemu X, Quek JP, Tam JP.

Angew Chem Int Ed Engl. 2016 Oct 4;55(41):12802-6. doi: 10.1002/anie.201607188. Epub 2016 Sep 14.

PMID:
27624217
16.

Human Coronaviruses: A Review of Virus-Host Interactions.

Lim YX, Ng YL, Tam JP, Liu DX.

Diseases. 2016 Jul 25;4(3). pii: E26. doi: 10.3390/diseases4030026. Review.

18.

Total Synthesis of Circular Bacteriocins by Butelase 1.

Hemu X, Qiu Y, Nguyen GK, Tam JP.

J Am Chem Soc. 2016 Jun 8;138(22):6968-71. doi: 10.1021/jacs.6b04310. Epub 2016 May 27.

PMID:
27206099
19.

Commercial processed soy-based food product contains glycated and glycoxidated lunasin proteoforms.

Serra A, Gallart-Palau X, See-Toh RS, Hemu X, Tam JP, Sze SK.

Sci Rep. 2016 May 18;6:26106. doi: 10.1038/srep26106.

20.

Immunostimulating and Gram-negative-specific antibacterial cyclotides from the butterfly pea (Clitoria ternatea).

Nguyen KN, Nguyen GK, Nguyen PQ, Ang KH, Dedon PC, Tam JP.

FEBS J. 2016 Jun;283(11):2067-90. doi: 10.1111/febs.13720. Epub 2016 Apr 20.

21.

A high-throughput peptidomic strategy to decipher the molecular diversity of cyclic cysteine-rich peptides.

Serra A, Hemu X, Nguyen GK, Nguyen NT, Sze SK, Tam JP.

Sci Rep. 2016 Mar 11;6:23005. doi: 10.1038/srep23005.

22.

Dementia-linked amyloidosis is associated with brain protein deamidation as revealed by proteomic profiling of human brain tissues.

Adav SS, Gallart-Palau X, Tan KH, Lim SK, Tam JP, Sze SK.

Mol Brain. 2016 Feb 19;9:20. doi: 10.1186/s13041-016-0200-z.

23.

Plasma proteome coverage is increased by unique peptide recovery from sodium deoxycholate precipitate.

Serra A, Zhu H, Gallart-Palau X, Park JE, Ho HH, Tam JP, Sze SK.

Anal Bioanal Chem. 2016 Mar;408(7):1963-73. doi: 10.1007/s00216-016-9312-7. Epub 2016 Jan 25.

PMID:
26804737
24.

Butelase 1: A Versatile Ligase for Peptide and Protein Macrocyclization.

Nguyen GK, Kam A, Loo S, Jansson AE, Pan LX, Tam JP.

J Am Chem Soc. 2015 Dec 16;137(49):15398-401. doi: 10.1021/jacs.5b11014. Epub 2015 Dec 7.

PMID:
26633100
25.

Antimicrobial Peptides from Plants.

Tam JP, Wang S, Wong KH, Tan WL.

Pharmaceuticals (Basel). 2015 Nov 16;8(4):711-57. doi: 10.3390/ph8040711. Review.

26.

Site-Specific N-Terminal Labeling of Peptides and Proteins using Butelase 1 and Thiodepsipeptide.

Nguyen GK, Cao Y, Wang W, Liu CF, Tam JP.

Angew Chem Int Ed Engl. 2015 Dec 21;54(52):15694-8. doi: 10.1002/anie.201506810. Epub 2015 Nov 13.

PMID:
26563575
27.

Cysteine-Rich Peptide Family with Unusual Disulfide Connectivity from Jasminum sambac.

Kumari G, Serra A, Shin J, Nguyen PQ, Sze SK, Yoon HS, Tam JP.

J Nat Prod. 2015 Nov 25;78(11):2791-9. doi: 10.1021/acs.jnatprod.5b00762. Epub 2015 Nov 10.

PMID:
26555361
28.

Antiviral Cystine Knot α-Amylase Inhibitors from Alstonia scholaris.

Nguyen PQ, Ooi JS, Nguyen NT, Wang S, Huang M, Liu DX, Tam JP.

J Biol Chem. 2015 Dec 25;290(52):31138-50. doi: 10.1074/jbc.M115.654855. Epub 2015 Nov 6.

29.

Studies on the Chitin Binding Property of Novel Cysteine-Rich Peptides from Alternanthera sessilis.

Kini SG, Nguyen PQ, Weissbach S, Mallagaray A, Shin J, Yoon HS, Tam JP.

Biochemistry. 2015 Nov 3;54(43):6639-49. doi: 10.1021/acs.biochem.5b00872. Epub 2015 Oct 21.

PMID:
26467613
30.

Butelase-mediated synthesis of protein thioesters and its application for tandem chemoenzymatic ligation.

Cao Y, Nguyen GK, Tam JP, Liu CF.

Chem Commun (Camb). 2015 Dec 18;51(97):17289-92. doi: 10.1039/c5cc07227a.

PMID:
26462854
31.

A novel strategy for the discrimination of gelatinous Chinese medicines based on enzymatic digestion followed by nano-flow liquid chromatography in tandem with orbitrap mass spectrum detection.

Yang H, Shen Y, Xu Y, Maqueda AS, Zheng J, Wu Q, Tam JP.

Int J Nanomedicine. 2015 Aug 5;10:4947-55. doi: 10.2147/IJN.S82291. eCollection 2015.

32.
33.

Allotides: Proline-Rich Cystine Knot α-Amylase Inhibitors from Allamanda cathartica.

Nguyen PQ, Luu TT, Bai Y, Nguyen GK, Pervushin K, Tam JP.

J Nat Prod. 2015 Apr 24;78(4):695-704. doi: 10.1021/np500866c. Epub 2015 Apr 2.

PMID:
25832441
34.

Tryptophan-dependent membrane interaction and heteromerization with the internal fusion peptide by the membrane proximal external region of SARS-CoV spike protein.

Liao Y, Zhang SM, Neo TL, Tam JP.

Biochemistry. 2015 Mar 10;54(9):1819-30. doi: 10.1021/bi501352u. Epub 2015 Feb 25.

PMID:
25668103
35.

Evaluation of the effect of trypsin digestion buffers on artificial deamidation.

Hao P, Ren Y, Datta A, Tam JP, Sze SK.

J Proteome Res. 2015 Feb 6;14(2):1308-14. doi: 10.1021/pr500903b. Epub 2014 Dec 22.

PMID:
25495137
36.

Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesis.

Dutta B, Yan R, Lim SK, Tam JP, Sze SK.

Mol Cell Proteomics. 2014 Dec;13(12):3236-49. doi: 10.1074/mcp.M114.038232. Epub 2014 Aug 6.

37.

Discovery and characterization of pseudocyclic cystine-knot α-amylase inhibitors with high resistance to heat and proteolytic degradation.

Nguyen PQ, Wang S, Kumar A, Yap LJ, Luu TT, Lescar J, Tam JP.

FEBS J. 2014 Oct;281(19):4351-66. doi: 10.1111/febs.12939. Epub 2014 Aug 8.

38.

Butelase 1 is an Asx-specific ligase enabling peptide macrocyclization and synthesis.

Nguyen GK, Wang S, Qiu Y, Hemu X, Lian Y, Tam JP.

Nat Chem Biol. 2014 Sep;10(9):732-8. doi: 10.1038/nchembio.1586. Epub 2014 Jul 20.

PMID:
25038786
39.

Profiling of the Chromatin-associated Proteome Identifies HP1BP3 as a Novel Regulator of Cell Cycle Progression.

Dutta B, Ren Y, Hao P, Sim KH, Cheow E, Adav S, Tam JP, Sze SK.

Mol Cell Proteomics. 2014 Sep;13(9):2183-97. doi: 10.1074/mcp.M113.034975. Epub 2014 May 15.

40.

Quantitative profiling of the rat heart myoblast secretome reveals differential responses to hypoxia and re-oxygenation stress.

Li X, Ren Y, Sorokin V, Poh KK, Ho HH, Lee CN, de Kleijn D, Lim SK, Tam JP, Sze SK.

J Proteomics. 2014 Feb 26;98:138-49. doi: 10.1016/j.jprot.2013.12.025. Epub 2014 Jan 9.

PMID:
24412200
41.

Correction of errors in tandem mass spectrum extraction enhances phosphopeptide identification.

Hao P, Ren Y, Tam JP, Sze SK.

J Proteome Res. 2013 Dec 6;12(12):5548-57. doi: 10.1021/pr4004486. Epub 2013 Nov 4.

PMID:
24147958
42.

Biomimetic synthesis of cyclic peptides using novel thioester surrogates.

Hemu X, Taichi M, Qiu Y, Liu DX, Tam JP.

Biopolymers. 2013 Sep;100(5):492-501. doi: 10.1002/bip.22308.

PMID:
23893856
43.

A thioethylalkylamido (TEA) thioester surrogate in the synthesis of a cyclic peptide via a tandem acyl shift.

Taichi M, Hemu X, Qiu Y, Tam JP.

Org Lett. 2013 Jun 7;15(11):2620-3. doi: 10.1021/ol400801k. Epub 2013 May 13.

PMID:
23668312
44.

Discovery of linear cyclotides in monocot plant Panicum laxum of Poaceae family provides new insights into evolution and distribution of cyclotides in plants.

Nguyen GK, Lian Y, Pang EW, Nguyen PQ, Tran TD, Tam JP.

J Biol Chem. 2013 Feb 1;288(5):3370-80. doi: 10.1074/jbc.M112.415356. Epub 2012 Nov 29.

45.

Chemical synthesis of circular proteins.

Tam JP, Wong CT.

J Biol Chem. 2012 Aug 3;287(32):27020-5. doi: 10.1074/jbc.R111.323568. Epub 2012 Jun 14. Review.

46.

A universal description for the experimental behavior of salt-(in)dependent oligocation-induced DNA condensation.

Korolev N, Berezhnoy NV, Eom KD, Tam JP, Nordenskiöld L.

Nucleic Acids Res. 2012 Mar;40(6):2808-21.

PMID:
22563605
47.

Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment.

Wong CT, Rowlands DK, Wong CH, Lo TW, Nguyen GK, Li HY, Tam JP.

Angew Chem Int Ed Engl. 2012 Jun 4;51(23):5620-4. doi: 10.1002/anie.201200984. Epub 2012 Apr 24. No abstract available.

PMID:
22532483
48.

Novel cyclotides and uncyclotides with highly shortened precursors from Chassalia chartacea and effects of methionine oxidation on bioactivities.

Nguyen GK, Lim WH, Nguyen PQ, Tam JP.

J Biol Chem. 2012 May 18;287(21):17598-607. doi: 10.1074/jbc.M111.338970. Epub 2012 Mar 30.

49.

Up-regulation of Mcl-1 and Bak by coronavirus infection of human, avian and animal cells modulates apoptosis and viral replication.

Zhong Y, Liao Y, Fang S, Tam JP, Liu DX.

PLoS One. 2012;7(1):e30191. doi: 10.1371/journal.pone.0030191. Epub 2012 Jan 11.

50.

The effect of salt on oligocation-induced chromatin condensation.

Korolev N, Zhao Y, Allahverdi A, Eom KD, Tam JP, Nordenskiöld L.

Biochem Biophys Res Commun. 2012 Feb 10;418(2):205-10. doi: 10.1016/j.bbrc.2011.12.112. Epub 2011 Dec 29.

PMID:
22227197

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