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Effects of AS2541019, a novel selective PI3Kδ inhibitor, on antibody production and hamster to rat xenotransplantation.

Marui T, Fukahori H, Kawashima T, Ito M, Akamatsu M, Kaneko Y, Takahashi F, Imada S, Morokata T.

Eur J Pharmacol. 2018 Mar 5;826:179-186. doi: 10.1016/j.ejphar.2018.02.046. [Epub ahead of print]


Application of the Self- Assembling Peptide P11-4 for Prevention of Acidic Erosion.

Suda S, Takamizawa T, Takahashi F, Tsujimoto A, Akiba S, Nagura Y, Kurokawa H, Miyazaki M.

Oper Dent. 2018 Mar 7. doi: 10.2341/17-175-L. [Epub ahead of print]


Electrochemical Determination of Chromium(VI) in River Water with Gold Nanoparticles-Graphene Nanocomposites Modified Electrodes.

Sari TK, Takahashi F, Jin J, Zein R, Munaf E.

Anal Sci. 2018;34(2):155-160. doi: 10.2116/analsci.34.155.


Optimal dose selection accounting for patient subpopulations in a randomized Phase II trial to maximize the success probability of a subsequent Phase III trial.

Takahashi F, Morita S.

J Biopharm Stat. 2018 Feb 8:1-14. doi: 10.1080/10543406.2018.1428614. [Epub ahead of print]


Non-small cell lung carcinoma with diffuse co-expression of thyroid transcription factor-1 and ΔNp63/p40.

Hayashi T, Takamochi K, Yanai Y, Mitani K, Tomita H, Mogushi K, Suehara Y, Takahashi F, Suzuki K, Saito T, Yao T.

Hum Pathol. 2018 Feb 1. pii: S0046-8177(18)30037-6. doi: 10.1016/j.humpath.2018.01.023. [Epub ahead of print]


Atlantooccipital overlapping and its effect on outcomes after ventral fixation in dogs with atlantoaxial instability.

Takahashi F, Hakozaki T, Kouno S, Suzuki S, Sato A, Kanno N, Harada Y, Yamaguchi S, Hara Y.

J Vet Med Sci. 2018 Feb 5. doi: 10.1292/jvms.17-0438. [Epub ahead of print]


Jejunal Metastasis from Hepatocellular Carcinoma.

Kanazawa M, Sugaya T, Tominaga K, Takahashi F, Takenaka K, Nakano M, Hiraishi H.

Intern Med. 2017 Dec 21. doi: 10.2169/internalmedicine.9625-17. [Epub ahead of print]


Enhancement of natural killer activity and IFN-γ production in an IL-12-dependent manner by a Brassica rapa L.

Yamamoto K, Furuya K, Yamada K, Takahashi F, Hamajima C, Tanaka S.

Biosci Biotechnol Biochem. 2017 Dec 6:1-15. doi: 10.1080/09168451.2017.1408396. [Epub ahead of print]


Assessment of T2 Relaxation Times for Normal Canine Knee Articular Cartilage by T2 Mapping Using 1.5-T Magnetic Resonance Imaging.

Matsui A, Shimizu M, Beale B, Takahashi F, Yamaguchi S.

Vet Comp Orthop Traumatol. 2017 Nov;30(6):391-397. doi: 10.3415/VCOT-17-01-0014. Epub 2017 Dec 4.


Evaluation of the dens-to-axis length ratio and dens angle in toy-breed dogs with and without atlantoaxial instability and in healthy Beagles.

Takahashi F, Hakozaki T, Kanno N, Harada Y, Yamaguchi S, Hara Y.

Am J Vet Res. 2017 Dec;78(12):1400-1405. doi: 10.2460/ajvr.78.12.1400.


A method of high-throughput functional evaluation of EGFR gene variants of unknown significance in cancer.

Kohsaka S, Nagano M, Ueno T, Suehara Y, Hayashi T, Shimada N, Takahashi K, Suzuki K, Takamochi K, Takahashi F, Mano H.

Sci Transl Med. 2017 Nov 15;9(416). pii: eaan6566. doi: 10.1126/scitranslmed.aan6566.


Assessing the effect of guideline introduction on clinical practice and outcome in patients with endometrial cancer in Japan: a project of the Japan Society of Gynecologic Oncology (JSGO) guideline evaluation committee.

Shigeta S, Nagase S, Mikami M, Ikeda M, Shida M, Sakaguchi I, Ushioda N, Takahashi F, Yamagami W, Yaegashi N, Udagawa Y, Katabuchi H.

J Gynecol Oncol. 2017 Nov;28(6):e76. doi: 10.3802/jgo.2017.28.e76.


Oxidized regenerated cellulose induces pleural thickening in patients with pneumothorax: possible involvement of the mesothelial-mesenchymal transition.

Ebana H, Hayashi T, Mitani K, Kobayashi E, Kumasaka T, Mizobuchi T, Kurihara M, Takahashi F, Takahashi K, Seyama K.

Surg Today. 2018 Apr;48(4):462-472. doi: 10.1007/s00595-017-1597-4. Epub 2017 Oct 12.


Bayesian noninferiority test for 2 binomial probabilities as the extension of Fisher exact test.

Doi M, Takahashi F, Kawasaki Y.

Stat Med. 2017 Dec 30;36(30):4789-4803. doi: 10.1002/sim.7495. Epub 2017 Sep 27.


LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer.

Jotatsu T, Yagishita S, Tajima K, Takahashi F, Mogushi K, Hidayat M, Wirawan A, Ko R, Kanemaru R, Shimada N, Mitani K, Saito T, Takamochi K, Suzuki K, Kohsaka S, Kojima S, Mukae H, Yatera K, Takahashi K.

Biochem Biophys Rep. 2016 Dec 1;9:86-94. doi: 10.1016/j.bbrep.2016.11.015. eCollection 2017 Mar.


BPM-CUL3 E3 ligase modulates thermotolerance by facilitating negative regulatory domain-mediated degradation of DREB2A in Arabidopsis.

Morimoto K, Ohama N, Kidokoro S, Mizoi J, Takahashi F, Todaka D, Mogami J, Sato H, Qin F, Kim JS, Fukao Y, Fujiwara M, Shinozaki K, Yamaguchi-Shinozaki K.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8528-E8536. doi: 10.1073/pnas.1704189114. Epub 2017 Sep 18.


Changes in Gut Microbial Ecology and Immunological Responses of Mice Fed the Insoluble Fraction of Brassica rapa L. that was Fermented or Not.

Tanaka S, Yamamoto K, Hamajima C, Takahashi F, Yamada K, Furuya K, Uyeno Y.

Microbes Environ. 2017 Sep 27;32(3):268-274. doi: 10.1264/jsme2.ME17059. Epub 2017 Sep 12.


Annual Report of the Committee on Gynecologic Oncology, Japan Society of Obstetrics and Gynecology: Patient Annual Report for 2014 and Treatment Annual Report for 2009.

Saito T, Takahashi F, Katabuchi H; 2016 Committee on Gynecologic Oncology of the Japan Society of Obstetrics and Gynecology.

J Obstet Gynaecol Res. 2017 Nov;43(11):1667-1677. doi: 10.1111/jog.13450. Epub 2017 Sep 11.


Post-hoc analysis of open-label extension period of study MCI186-19 in amyotrophic lateral sclerosis.

Takei K, Tsuda K, Takahashi F, Palumbo J.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 Oct;18(sup1):64-70. doi: 10.1080/21678421.2017.1365372.


Post-hoc analysis of MCI186-17, the extension study to MCI186-16, the confirmatory double-blind, parallel-group, placebo-controlled study of edaravone in amyotrophic lateral sclerosis.

Takahashi F, Takei K, Tsuda K, Palumbo J.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 Oct;18(sup1):32-39. doi: 10.1080/21678421.2017.1361442.


Post-hoc analysis of randomised, placebo-controlled, double-blind study (MCI186-19) of edaravone (MCI-186) in amyotrophic lateral sclerosis.

Takei K, Takahashi F, Liu S, Tsuda K, Palumbo J.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 Oct;18(sup1):49-54. doi: 10.1080/21678421.2017.1361443.


An assessment of treatment guidelines, clinical practices, demographics, and progression of disease among patients with amyotrophic lateral sclerosis in Japan, the United States, and Europe.

Takei K, Tsuda K, Takahashi F, Hirai M, Palumbo J.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 Oct;18(sup1):88-97. doi: 10.1080/21678421.2017.1361445.


A prospective study of palonosetron for prevention of chemotherapy-induced nausea and vomiting in malignant lymphoma patients following highly emetogenic chemotherapy.

Takahashi T, Okada T, Ikejiri F, Ito S, Okada Y, Takahashi F, Kumanomido S, Jo Y, Adachi K, Onishi C, Kawakami K, Miyake T, Inoue M, Suzuki R, Suzumiya J.

Int J Clin Oncol. 2018 Feb;23(1):189-194. doi: 10.1007/s10147-017-1173-3. Epub 2017 Aug 19.


Current use of direct oral anticoagulants for atrial fibrillation in Japan: Findings from the SAKURA AF Registry.

Okumura Y, Yokoyama K, Matsumoto N, Tachibana E, Kuronuma K, Oiwa K, Matsumoto M, Kojima T, Hanada S, Nomoto K, Arima K, Takahashi F, Kotani T, Ikeya Y, Fukushima S, Itoh S, Kondo K, Chiku M, Ohno Y, Onikura M, Hirayama A, The Sakura Af Registry Investigators.

J Arrhythm. 2017 Aug;33(4):289-296. doi: 10.1016/j.joa.2016.11.003. Epub 2017 Jan 2.


DNA mismatch repair deficiency in surgically resected lung adenocarcinoma: Microsatellite instability analysis using the Promega panel.

Takamochi K, Takahashi F, Suehara Y, Sato E, Kohsaka S, Hayashi T, Kitano S, Uneno T, Kojima S, Takeuchi K, Mano H, Suzuki K.

Lung Cancer. 2017 Aug;110:26-31. doi: 10.1016/j.lungcan.2017.05.016. Epub 2017 May 21.


Molecular evolutionary analysis of a gender-limited MID ortholog from the homothallic species Volvox africanus with male and monoecious spheroids.

Yamamoto K, Kawai-Toyooka H, Hamaji T, Tsuchikane Y, Mori T, Takahashi F, Sekimoto H, Ferris PJ, Nozaki H.

PLoS One. 2017 Jun 30;12(6):e0180313. doi: 10.1371/journal.pone.0180313. eCollection 2017.


Early impact of the Japanese immunization program implemented before the HPV vaccination crisis.

Matsumoto K, Yaegashi N, Iwata T, Yamamoto K, Nagashima M, Saito T, Ushijima K, Takahashi F, Noda K, Yoshikawa H.

Int J Cancer. 2017 Oct 15;141(8):1704-1706. doi: 10.1002/ijc.30855. Epub 2017 Jul 12. No abstract available.


Comparison of the Analytical Performance Between cobas EGFR Assay and PCR-Clamp Method in the Detection of EGFR Mutations in Japanese Non-Small Cell Lung Cancer Patients.

Ai T, Yuri M, Tabe Y, Kakimoto A, Morishita S, Tsuchiya K, Takamochi K, Kodama Y, Takahashi F, Shigeki M, Horii T, Suzuki K, Takahashi K, Miida T, Ohsaka A.

Clin Lab. 2017 May 1;63(5):1021-1026. doi: 10.7754/Clin.Lab.2017.161223.


Surfactant protein-D predicts prognosis of interstitial lung disease induced by anticancer agents in advanced lung cancer: a case control study.

Nakamura K, Kato M, Shukuya T, Mori K, Sekimoto Y, Ihara H, Kanemaru R, Ko R, Shibayama R, Tajima K, Koyama R, Shimada N, Nagashima O, Takahashi F, Sasaki S, Takahashi K.

BMC Cancer. 2017 May 2;17(1):302. doi: 10.1186/s12885-017-3285-6.


CD44 silencing decreases the expression of stem cell-related factors induced by transforming growth factor β1 and tumor necrosis factor α in lung cancer: Preliminary findings.

Nurwidya F, Takahashi F, Kato M, Baskoro H, Hidayat M, Wirawan A, Takahashi K.

Bosn J Basic Med Sci. 2017 Aug 20;17(3):228-234. doi: 10.17305/bjbms.2017.1966.


Overexpression of an Arabidopsis thaliana galactinol synthase gene improves drought tolerance in transgenic rice and increased grain yield in the field.

Selvaraj MG, Ishizaki T, Valencia M, Ogawa S, Dedicova B, Ogata T, Yoshiwara K, Maruyama K, Kusano M, Saito K, Takahashi F, Shinozaki K, Nakashima K, Ishitani M.

Plant Biotechnol J. 2017 Nov;15(11):1465-1477. doi: 10.1111/pbi.12731. Epub 2017 May 3.


Corrigendum to "Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3" [Bioorg. Med. Chem. 23 (2015) 4871-4883].

Nakajima Y, Inoue T, Nakai K, Mukoyoshi K, Hamaguchi H, Hatanaka K, Sasaki H, Tanaka A, Takahashi F, Kunikawa S, Usuda H, Moritomo A, Higashi Y, Inami M, Shirakami S.

Bioorg Med Chem. 2017 May 15;25(10):2813. doi: 10.1016/j.bmc.2017.03.043. Epub 2017 Mar 30. No abstract available.


Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature.

Kidokoro S, Yoneda K, Takasaki H, Takahashi F, Shinozaki K, Yamaguchi-Shinozaki K.

Plant Cell. 2017 Apr;29(4):760-774. doi: 10.1105/tpc.16.00669. Epub 2017 Mar 28.


Incidence and prevalence of systemic sclerosis in Campo Grande, State of Mato Grosso do Sul, Brazil.

Horimoto AMC, Matos ENN, Costa MRD, Takahashi F, Rezende MC, Kanomata LB, Locatelli EPP, Finotti LT, Maegawa FKM, Rondon RMR, Machado NP, Couto FMAATD, Figueiredo TPA, Ovidio RA, Costa IPD.

Rev Bras Reumatol Engl Ed. 2017 Mar - Apr;57(2):107-114. doi: 10.1016/j.rbre.2016.09.005. Epub 2016 Oct 15. English, Portuguese.


Longitudinal changes of ocular blood flow using laser speckle flowgraphy during normal pregnancy.

Sato T, Sugawara J, Aizawa N, Iwama N, Takahashi F, Nakamura-Kurakata M, Saito M, Sugiyama T, Kunikata H, Nakazawa T, Yaegashi N.

PLoS One. 2017 Mar 3;12(3):e0173127. doi: 10.1371/journal.pone.0173127. eCollection 2017.


Biomechanical evaluation of three ventral fixation methods for canine atlantoaxial instability: a cadaveric study.

Takahashi F, Hakozaki T, Kanno N, Harada Y, Yamaguchi S, Hara Y.

J Vet Med Sci. 2017;79(2):e1. doi: 10.1292/jvms.16-0160e.


Clinical statistics of gynecologic cancers in Japan.

Yamagami W, Nagase S, Takahashi F, Ino K, Hachisuga T, Aoki D, Katabuchi H.

J Gynecol Oncol. 2017 Mar;28(2):e32. doi: 10.3802/jgo.2017.28.e32. Epub 2017 Feb 10. Review.


Endoscopic balloon dilation for stenotic lesions in Crohn's disease.

Kanamori A, Sugaya T, Tominaga K, Takahashi F, Takenaka K, Hoshino A, Koike T, Nakano M, Hiraishi H.

Turk J Gastroenterol. 2017 Mar;28(2):117-124. doi: 10.5152/tjg.2017.16598. Epub 2017 Feb 14.


Current Status of Uterine Leiomyosarcoma in the Tohoku Region: Results of the Tohoku Translational Center Development Network Survey.

Tokunaga H, Takahashi F, Yamamoto H, Honda T, Watanabe T, Shoji T, Sugiyama T, Yamada H, Tando T, Yoshinaga K, Kagabu S, Otsuki T, Kin S, Yokoyama Y, Wagatsuma S, Sato K, Sato H, Oishi T, Yoshida Y, Hayasaka T, Matsui T, Imai N, Nishigori H, Shimokawa H, Yaegashi N, Watanabe Y.

Int J Clin Oncol. 2017 Jun;22(3):541-547. doi: 10.1007/s10147-017-1097-y. Epub 2017 Feb 10.


Pregnant Women's Awareness of Social Capital in the Great East Japan Earthquake-Affected Areas of Miyagi Prefecture: The Japan Environment and Children's Study.

Nishigori H, Nishigori T, Sakurai K, Mizuno S, Obara T, Metoki H, Watanabe Z, Iwama N, Ishikuro M, Tatsuta N, Nishijima I, Sugawara J, Kuriyama S, Fujiwara I, Arima T, Nakai K, Takahashi F, Yaegashi N; Japan Environment & Children’s Study Group.

Disaster Med Public Health Prep. 2017 Jun;11(3):355-364. doi: 10.1017/dmp.2016.150. Epub 2017 Jan 17.


ABA-unresponsive SnRK2 protein kinases regulate mRNA decay under osmotic stress in plants.

Soma F, Mogami J, Yoshida T, Abekura M, Takahashi F, Kidokoro S, Mizoi J, Shinozaki K, Yamaguchi-Shinozaki K.

Nat Plants. 2017 Jan 6;3:16204. doi: 10.1038/nplants.2016.204.


Progressive Multifocal Micronodular Pneumocyte Hyperplasia in the Lungs of a Patient with Tuberous Sclerosis Complex: A Case Report.

Urano T, Hayama N, Tanaka J, Horio Y, Sato M, Hattori S, Takahashi G, Takahashi F, Takeuchi T, Harada K, Takiguchi H, Tomomatsu H, Tomomatsu K, Takihara T, Niimi K, Oguma T, Aoki T, Ogura G, Nakamura N, Asano K.

Tokai J Exp Clin Med. 2016 Dec 20;41(4):230-232.


An adenylyl cyclase with a phosphodiesterase domain in basal plants with a motile sperm system.

Kasahara M, Suetsugu N, Urano Y, Yamamoto C, Ohmori M, Takada Y, Okuda S, Nishiyama T, Sakayama H, Kohchi T, Takahashi F.

Sci Rep. 2016 Dec 16;6:39232. doi: 10.1038/srep39232.


Fermented Food Consumption and Psychological Distress in Pregnant Women: A Nationwide Birth Cohort Study of the Japan Environment and Children's Study.

Takahashi F, Nishigori H, Nishigori T, Mizuno S, Obara T, Metoki H, Sakurai K, Ishikuro M, Iwama N, Tatsuta N, Nishijima I, Fujiwara I, Arima T, Nakai K, Sugiyama T, Kuriyama S, Yaegashi N; Japan Environment & Children’s Study Group.

Tohoku J Exp Med. 2016 Dec;240(4):309-321.


Haploinsufficiency of the folliculin gene leads to impaired functions of lung fibroblasts in patients with Birt-Hogg-Dubé syndrome.

Hoshika Y, Takahashi F, Togo S, Hashimoto M, Nara T, Kobayashi T, Nurwidya F, Kataoka H, Kurihara M, Kobayashi E, Ebana H, Kikkawa M, Ando K, Nishino K, Hino O, Takahashi K, Seyama K.

Physiol Rep. 2016 Nov;4(21). pii: e13025. Epub 2016 Nov 15.


A New Morphological Type of Volvox from Japanese Large Lakes and Recent Divergence of this Type and V. ferrisii in Two Different Freshwater Habitats.

Nozaki H, Ueki N, Isaka N, Saigo T, Yamamoto K, Matsuzaki R, Takahashi F, Wakabayashi KI, Kawachi M.

PLoS One. 2016 Nov 23;11(11):e0167148. doi: 10.1371/journal.pone.0167148. eCollection 2016.


Autofluorescence imaging bronchoscopy as a novel approach to the management of tracheobronchopathia osteochondroplastica: a case report.

Ihara H, Tajima K, Yoshikawa H, Tajima M, Harada N, Takahashi F, Uekusa T, Nagaoka T, Takahashi K.

J Thorac Dis. 2016 Oct;8(10):E1195-E1198.


Identification of the fatty alcohol oxidase FAO1 from Starmerella bombicola and improved novel glycolipids production in an FAO1 knockout mutant.

Takahashi F, Igarashi K, Hagihara H.

Appl Microbiol Biotechnol. 2016 Nov;100(22):9519-9528. Epub 2016 Jul 6.


Hepatic Portal Venous Gas Caused by Endoscopic Balloon Dilatation for Crohn's Stenosis.

Takahashi F, Tominaga K, Hiraishi H.

Clin Gastroenterol Hepatol. 2016 Dec;14(12):A23-A24. doi: 10.1016/j.cgh.2016.08.029. Epub 2016 Aug 28. No abstract available.


Evaluation of the Japanese Metabolic Syndrome Risk Score (JAMRISC): a newly developed questionnaire used as a screening tool for diagnosing metabolic syndrome and insulin resistance in Japan.

Tan C, Sasagawa Y, Kamo KI, Kukitsu T, Noda S, Ishikawa K, Yamauchi N, Saikawa T, Noro T, Nakamura H, Takahashi F, Sata F, Tada M, Kokai Y.

Environ Health Prev Med. 2016 Nov;21(6):470-479. Epub 2016 Oct 3.

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