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Items: 1 to 50 of 239

1.

Cellularity of Thymic Epithelial Cells in the Postnatal Mouse.

Sakata M, Ohigashi I, Takahama Y.

J Immunol. 2018 Feb 15;200(4):1382-1388. doi: 10.4049/jimmunol.1701235. Epub 2018 Jan 3.

PMID:
29298829
2.

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Cossarizza A, Chang HD, Radbruch A, Akdis M, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, Boulais PE, Brinkman RR, Büscher M, Busch DH, Bushnell TP, Cao X, Cavani A, Chattopadhyay PK, Cheng Q, Chow S, Clerici M, Cooke A, Cosma A, Cosmi L, Cumano A, Dang VD, Davies D, De Biasi S, Del Zotto G, Della Bella S, Dellabona P, Deniz G, Dessing M, Diefenbach A, Di Santo J, Dieli F, Dolf A, Donnenberg VS, Dörner T, Ehrhardt GRA, Endl E, Engel P, Engelhardt B, Esser C, Everts B, Dreher A, Falk CS, Fehniger TA, Filby A, Fillatreau S, Follo M, Förster I, Foster J, Foulds GA, Frenette PS, Galbraith D, Garbi N, García-Godoy MD, Geginat J, Ghoreschi K, Gibellini L, Goettlinger C, Goodyear CS, Gori A, Grogan J, Gross M, Grützkau A, Grummitt D, Hahn J, Hammer Q, Hauser AE, Haviland DL, Hedley D, Herrera G, Herrmann M, Hiepe F, Holland T, Hombrink P, Houston JP, Hoyer BF, Huang B, Hunter CA, Iannone A, Jäck HM, Jávega B, Jonjic S, Juelke K, Jung S, Kaiser T, Kalina T, Keller B, Khan S, Kienhöfer D, Kroneis T, Kunkel D, Kurts C, Kvistborg P, Lannigan J, Lantz O, Larbi A, LeibundGut-Landmann S, Leipold MD, Levings MK, Litwin V, Liu Y, Lohoff M, Lombardi G, Lopez L, Lovett-Racke A, Lubberts E, Ludewig B, Lugli E, Maecker HT, Martrus G, Matarese G, Maueröder C, McGrath M, McInnes I, Mei HE, Melchers F, Melzer S, Mielenz D, Mills K, Mirrer D, Mjösberg J, Moore J, Moran B, Moretta A, Moretta L, Mosmann TR, Müller S, Müller W, Münz C, Multhoff G, Munoz LE, Murphy KM, Nakayama T, Nasi M, Neudörfl C, Nolan J, Nourshargh S, O'Connor JE, Ouyang W, Oxenius A, Palankar R, Panse I, Peterson P, Peth C, Petriz J, Philips D, Pickl W, Piconese S, Pinti M, Pockley AG, Podolska MJ, Pucillo C, Quataert SA, Radstake TRDJ, Rajwa B, Rebhahn JA, Recktenwald D, Remmerswaal EBM, Rezvani K, Rico LG, Robinson JP, Romagnani C, Rubartelli A, Ruckert B, Ruland J, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sawitzki B, Scheffold A, Schiemann M, Schildberg F, Schimisky E, Schmid SA, Schmitt S, Schober K, Schüler T, Schulz AR, Schumacher T, Scotta C, Shankey TV, Shemer A, Simon AK, Spidlen J, Stall AM, Stark R, Stehle C, Stein M, Steinmetz T, Stockinger H, Takahama Y, Tarnok A, Tian Z, Toldi G, Tornack J, Traggiai E, Trotter J, Ulrich H, van der Braber M, van Lier RAW, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk HD, von Volkmann K, Waisman A, Walker R, Ward MD, Warnatz K, Warth S, Watson JV, Watzl C, Wegener L, Wiedemann A, Wienands J, Willimsky G, Wing J, Wurst P, Yu L, Yue A, Zhang Q, Zhao Y, Ziegler S, Zimmermann J.

Eur J Immunol. 2017 Oct;47(10):1584-1797. doi: 10.1002/eji.201646632. No abstract available.

PMID:
29023707
3.

Essential role of CCL21 in establishment of central self-tolerance in T cells.

Kozai M, Kubo Y, Katakai T, Kondo H, Kiyonari H, Schaeuble K, Luther SA, Ishimaru N, Ohigashi I, Takahama Y.

J Exp Med. 2017 Jul 3;214(7):1925-1935. doi: 10.1084/jem.20161864. Epub 2017 Jun 13.

4.

MiCASA is a new method for quantifying cellular organization.

Sornborger A, Li J, Timmons C, Lupu F, Eggenschwiler J, Takahama Y, Manley NR.

Nat Commun. 2017 May 30;8:15619. doi: 10.1038/ncomms15619.

5.

A human PSMB11 variant affects thymoproteasome processing and CD8+ T cell production.

Ohigashi I, Ohte Y, Setoh K, Nakase H, Maekawa A, Kiyonari H, Hamazaki Y, Sekai M, Sudo T, Tabara Y, Sawai H, Omae Y, Yuliwulandari R, Tanaka Y, Mizokami M, Inoue H, Kasahara M, Minato N, Tokunaga K, Tanaka K, Matsuda F, Murata S, Takahama Y.

JCI Insight. 2017 May 18;2(10). pii: 93664. doi: 10.1172/jci.insight.93664. [Epub ahead of print]

6.

Antigen processing and presentation in the thymus: implications for T cell repertoire selection.

Kondo K, Takada K, Takahama Y.

Curr Opin Immunol. 2017 Jun;46:53-57. doi: 10.1016/j.coi.2017.03.014. Epub 2017 May 3. Review.

PMID:
28477557
7.

Generation of diversity in thymic epithelial cells.

Takahama Y, Ohigashi I, Baik S, Anderson G.

Nat Rev Immunol. 2017 May;17(5):295-305. doi: 10.1038/nri.2017.12. Epub 2017 Mar 20. Review.

PMID:
28317923
8.

Generation of Peptides That Promote Positive Selection in the Thymus.

Takada K, Kondo K, Takahama Y.

J Immunol. 2017 Mar 15;198(6):2215-2222. doi: 10.4049/jimmunol.1601862. Review.

9.

Foxn1-β5t transcriptional axis controls CD8+ T-cell production in the thymus.

Uddin MM, Ohigashi I, Motosugi R, Nakayama T, Sakata M, Hamazaki J, Nishito Y, Rode I, Tanaka K, Takemoto T, Murata S, Takahama Y.

Nat Commun. 2017 Feb 8;8:14419. doi: 10.1038/ncomms14419.

10.

[A Case of Solitary Metastasis to the Small Intestine from Sigmoid Colon Cancer after Treatment of Seven Multiple Cancers].

Nasu K, Maeshiro T, Yanai K, Fujita H, Machida M, Moriyama T, Koseki T, Kudo H, Inada K, Takahama Y, Seyama Y, Wada I, Miyamoto S, Umekita N, Tanizawa T.

Gan To Kagaku Ryoho. 2016 Nov;43(12):1809-1811. Japanese.

PMID:
28133139
11.

Tyramine and β-phenylethylamine, from fermented food products, as agonists for the human trace amine-associated receptor 1 (hTAAR1) in the stomach.

Ohta H, Takebe Y, Murakami Y, Takahama Y, Morimura S.

Biosci Biotechnol Biochem. 2017 May;81(5):1002-1006. doi: 10.1080/09168451.2016.1274640. Epub 2017 Jan 13.

PMID:
28084165
12.

A recombinant vesicular stomatitis virus encoding CCR5-tropic HIV-1 receptors targets HIV-1-infected cells and controls HIV-1 infection.

Okuma K, Fukagawa K, Kohma T, Takahama Y, Hamaguchi Y, Ito M, Tanaka Y, Buonocore L, Rose JK, Hamaguchi I.

Microbes Infect. 2017 Apr - May;19(4-5):277-287. doi: 10.1016/j.micinf.2016.12.004. Epub 2016 Dec 24.

PMID:
28025070
13.

Heteroarene-Directed Oxidative sp(2) C-H Bond Allylation with Aliphatic Alkenes Catalyzed by an (Electron-Deficient η(5)-Cyclopentadienyl)rhodium(III) Complex.

Takahama Y, Shibata Y, Tanaka K.

Org Lett. 2016 Jun 17;18(12):2934-7. doi: 10.1021/acs.orglett.6b01288. Epub 2016 May 26.

PMID:
27227320
14.

Development and developmental potential of cortical thymic epithelial cells.

Ohigashi I, Kozai M, Takahama Y.

Immunol Rev. 2016 May;271(1):10-22. doi: 10.1111/imr.12404. Review.

PMID:
27088904
15.

Dynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla.

Mayer CE, Žuklys S, Zhanybekova S, Ohigashi I, Teh HY, Sansom SN, Shikama-Dorn N, Hafen K, Macaulay IC, Deadman ME, Ponting CP, Takahama Y, Holländer GA.

Eur J Immunol. 2016 Apr;46(4):846-56. doi: 10.1002/eji.201545995. Epub 2016 Jan 18.

16.

Adult Thymic Medullary Epithelium Is Maintained and Regenerated by Lineage-Restricted Cells Rather Than Bipotent Progenitors.

Ohigashi I, Zuklys S, Sakata M, Mayer CE, Hamazaki Y, Minato N, Hollander GA, Takahama Y.

Cell Rep. 2015 Nov 17;13(7):1432-1443. doi: 10.1016/j.celrep.2015.10.012. Epub 2015 Nov 5.

17.

Cultural Difference in Conflict Management Strategies of Children and Its Development: Comparing 3- and 5-Year-Olds Across China, Japan, and Korea.

Maruyama H, Ujiie T, Takai J, Takahama Y, Sakagami H, Shibayama M, Fukumoto M, Ninomiya K, Hyang Ah P, Feng X, Takatsuji C, Hirose M, Kudo R, Shima Y, Nakayama R, Hamaie N, Zhang F, Moriizumi S.

Early Educ Dev. 2015 Nov 17;26(8):1210-1233. Epub 2015 May 26.

18.

TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8(+) T cells.

Takada K, Van Laethem F, Xing Y, Akane K, Suzuki H, Murata S, Tanaka K, Jameson SC, Singer A, Takahama Y.

Nat Immunol. 2015 Oct;16(10):1069-76. doi: 10.1038/ni.3237. Epub 2015 Aug 24.

19.

Flow Cytometry Analysis of Thymic Epithelial Cells and Their Subpopulations.

Ohigashi I, Takahama Y.

Methods Mol Biol. 2016;1323:65-73. doi: 10.1007/978-1-4939-2809-5_5.

PMID:
26294398
20.

Thymoproteasomes produce unique peptide motifs for positive selection of CD8(+) T cells.

Sasaki K, Takada K, Ohte Y, Kondo H, Sorimachi H, Tanaka K, Takahama Y, Murata S.

Nat Commun. 2015 Jun 23;6:7484. doi: 10.1038/ncomms8484.

21.

Protection from diet-induced obesity and insulin resistance in mice lacking CCL19-CCR7 signaling.

Sano T, Iwashita M, Nagayasu S, Yamashita A, Shinjo T, Hashikata A, Asano T, Kushiyama A, Ishimaru N, Takahama Y, Nishimura F.

Obesity (Silver Spring). 2015 Jul;23(7):1460-71. doi: 10.1002/oby.21127. Epub 2015 Jun 12.

22.

Oxidative Olefination of Anilides with Unactivated Alkenes Catalyzed by an (Electron-Deficient η(5) -Cyclopentadienyl)Rhodium(III) Complex Under Ambient Conditions.

Takahama Y, Shibata Y, Tanaka K.

Chemistry. 2015 Jun 15;21(25):9053-6. doi: 10.1002/chem.201501232. Epub 2015 May 11.

PMID:
25963174
23.

Development of an infectious surrogate hepatitis C virus based on a recombinant vesicular stomatitis virus expressing hepatitis C virus envelope glycoproteins and green fluorescent protein.

Okuma K, Fukagawa K, Tateyama S, Kohma T, Mochida K, Hiyoshi M, Takahama Y, Hamaguchi Y, Hirose K, Buonocore L, Rose JK, Mizuochi T, Hamaguchi I.

Jpn J Infect Dis. 2015;68(3):203-8. doi: 10.7883/yoken.JJID.2014.328. Epub 2014 Dec 24.

24.

Positive-selection-inducing self-peptides displayed by cortical thymic epithelial cells.

Takada K, Takahama Y.

Adv Immunol. 2015;125:87-110. doi: 10.1016/bs.ai.2014.09.003. Epub 2014 Dec 24. Review.

PMID:
25591465
25.

CCRL1 marks heterogeneity in cortical and medullary thymic epithelial cells.

Ohigashi I, Takahama Y.

Eur J Immunol. 2014 Oct;44(10):2872-5. doi: 10.1002/eji.201445091.

26.

Alpha-smooth muscle actin expression identifies subpopulations of mouse lymph node non-hematopoietic cells.

Togoo K, Takahama Y, Takada K.

Biochem Biophys Res Commun. 2014 Jun 27;449(2):241-7. doi: 10.1016/j.bbrc.2014.05.023. Epub 2014 May 17.

PMID:
24845380
27.

Increased number of Hassall's corpuscles in myasthenia gravis patients with thymic hyperplasia.

Matsui N, Ohigashi I, Tanaka K, Sakata M, Furukawa T, Nakagawa Y, Kondo K, Kitagawa T, Yamashita S, Nomura Y, Takahama Y, Kaji R.

J Neuroimmunol. 2014 Apr 15;269(1-2):56-61. doi: 10.1016/j.jneuroim.2014.01.011. Epub 2014 Jan 28.

PMID:
24556356
28.

Gimap3 and Gimap5 cooperate to maintain T-cell numbers in the mouse.

Yano K, Carter C, Yoshida N, Abe T, Yamada A, Nitta T, Ishimaru N, Takada K, Butcher GW, Takahama Y.

Eur J Immunol. 2014 Feb;44(2):561-72. doi: 10.1002/eji.201343750. Epub 2013 Oct 23.

29.

Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways.

Williams JA, Zhang J, Jeon H, Nitta T, Ohigashi I, Klug D, Kruhlak MJ, Choudhury B, Sharrow SO, Granger L, Adams A, Eckhaus MA, Jenkinson SR, Richie ER, Gress RE, Takahama Y, Hodes RJ.

J Immunol. 2014 Jan 15;192(2):630-40. doi: 10.4049/jimmunol.1302550. Epub 2013 Dec 13.

30.

TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development.

Jenkinson SR, Williams JA, Jeon H, Zhang J, Nitta T, Ohigashi I, Kruhlak M, Zuklys S, Sharrow S, Adams A, Granger L, Choi Y, Siebenlist U, Bishop GA, Hollander GA, Takahama Y, Hodes RJ.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21107-12. doi: 10.1073/pnas.1314859111. Epub 2013 Dec 9.

31.

Serial progression of cortical and medullary thymic epithelial microenvironments.

Alves NL, Takahama Y, Ohigashi I, Ribeiro AR, Baik S, Anderson G, Jenkinson WE.

Eur J Immunol. 2014 Jan;44(1):16-22. doi: 10.1002/eji.201344110. Epub 2013 Dec 4. Review. Erratum in: Eur J Immunol. 2014 Jul;44(7):2197.

32.

Role of macrophage-derived hypoxia-inducible factor (HIF)-1α as a mediator of vascular remodelling.

Nakayama T, Kurobe H, Sugasawa N, Kinoshita H, Higashida M, Matsuoka Y, Yoshida Y, Hirata Y, Sakata M, Maxfield MW, Shimabukuro M, Takahama Y, Sata M, Tamaki T, Kitagawa T, Tomita S.

Cardiovasc Res. 2013 Sep 1;99(4):705-15. doi: 10.1093/cvr/cvt146. Epub 2013 Jun 10.

PMID:
23752975
33.

Cell-autonomous defects in thymic epithelial cells disrupt endothelial-perivascular cell interactions in the mouse thymus.

Bryson JL, Griffith AV, Hughes B 3rd, Saito F, Takahama Y, Richie ER, Manley NR.

PLoS One. 2013 Jun 4;8(6):e65196. doi: 10.1371/journal.pone.0065196. Print 2013.

34.

Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells.

Ohigashi I, Zuklys S, Sakata M, Mayer CE, Zhanybekova S, Murata S, Tanaka K, Holländer GA, Takahama Y.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9885-90. doi: 10.1073/pnas.1301799110. Epub 2013 May 29.

35.

Reconstruction of a robust glycodiagnostic agent supported by multiple lectin-assisted glycan profiling.

Kuno A, Sato T, Shimazaki H, Unno S, Saitou K, Kiyohara K, Sogabe M, Tsuruno C, Takahama Y, Ikehara Y, Narimatsu H.

Proteomics Clin Appl. 2013 Oct;7(9-10):642-7. doi: 10.1002/prca.201300010. Epub 2013 Aug 7.

PMID:
23640794
36.

Development and function of cortical thymic epithelial cells.

Takada K, Ohigashi I, Kasai M, Nakase H, Takahama Y.

Curr Top Microbiol Immunol. 2014;373:1-17. doi: 10.1007/82_2013_322. Review.

PMID:
23612989
37.

Lymphotoxin β receptor regulates the development of CCL21-expressing subset of postnatal medullary thymic epithelial cells.

Lkhagvasuren E, Sakata M, Ohigashi I, Takahama Y.

J Immunol. 2013 May 15;190(10):5110-7. doi: 10.4049/jimmunol.1203203. Epub 2013 Apr 12.

38.

Emphysematous cholecystitis with massive gas in the abdominal cavity.

Miyahara H, Shida D, Matsunaga H, Takahama Y, Miyamoto S.

World J Gastroenterol. 2013 Jan 28;19(4):604-6. doi: 10.3748/wjg.v19.i4.604.

40.

Complete but not partial thymectomy in early infancy reduces T-cell-mediated immune response: three-year tracing study after pediatric cardiac surgery.

Kurobe H, Tominaga T, Sugano M, Hayabuchi Y, Egawa Y, Takahama Y, Kitagawa T.

J Thorac Cardiovasc Surg. 2013 Mar;145(3):656-62, 662.e1-2; discussion 662. doi: 10.1016/j.jtcvs.2012.12.015. Epub 2013 Jan 9.

41.

[Anesthetic consideration in patients undergoing catheter ablation for atrial fibrillation].

Oda T, Takahama Y.

Masui. 2012 Nov;61(11):1199-204. Japanese.

PMID:
23236926
42.

Thymic nurse cells provide microenvironment for secondary T cell receptor α rearrangement in cortical thymocytes.

Nakagawa Y, Ohigashi I, Nitta T, Sakata M, Tanaka K, Murata S, Kanagawa O, Takahama Y.

Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20572-7. doi: 10.1073/pnas.1213069109. Epub 2012 Nov 27.

43.

The development of T lymphocytes in fetal thymus organ culture.

Nitta T, Ohigashi I, Takahama Y.

Methods Mol Biol. 2013;946:85-102. doi: 10.1007/978-1-62703-128-8_6.

PMID:
23179827
44.

MicroRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection.

Zuklys S, Mayer CE, Zhanybekova S, Stefanski HE, Nusspaumer G, Gill J, Barthlott T, Chappaz S, Nitta T, Dooley J, Nogales-Cadenas R, Takahama Y, Finke D, Liston A, Blazar BR, Pascual-Montano A, Holländer GA.

J Immunol. 2012 Oct 15;189(8):3894-904. doi: 10.4049/jimmunol.1200783. Epub 2012 Sep 12.

45.

Pulmonary rehabilitation program including respiratory conditioning for chronic obstructive pulmonary disease (COPD): Improved hyperinflation and expiratory flow during tidal breathing.

Yoshimi K, Ueki J, Seyama K, Takizawa M, Yamaguchi S, Kitahara E, Fukazawa S, Takahama Y, Ichikawa M, Takahashi K, Fukuchi Y.

J Thorac Dis. 2012 Jun 1;4(3):259-64. doi: 10.3978/j.issn.2072-1439.2012.03.17.

46.

Thymic epithelial cells: working class heroes for T cell development and repertoire selection.

Anderson G, Takahama Y.

Trends Immunol. 2012 Jun;33(6):256-63. doi: 10.1016/j.it.2012.03.005. Epub 2012 May 14. Review.

PMID:
22591984
47.

[T lymphocyte development and selection in the thymic microenvironments].

Takahama Y.

Seikagaku. 2012 Mar;84(3):177-82. Review. Japanese. No abstract available.

PMID:
22568069
48.

[Synthesis and analysis of multi-dimentional immune organ network].

Takahama Y, Minato N.

Seikagaku. 2012 Mar;84(3):161-2. Review. Japanese. No abstract available.

PMID:
22568066
49.

Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium.

Roberts NA, White AJ, Jenkinson WE, Turchinovich G, Nakamura K, Withers DR, McConnell FM, Desanti GE, Benezech C, Parnell SM, Cunningham AF, Paolino M, Penninger JM, Simon AK, Nitta T, Ohigashi I, Takahama Y, Caamano JH, Hayday AC, Lane PJ, Jenkinson EJ, Anderson G.

Immunity. 2012 Mar 23;36(3):427-37. doi: 10.1016/j.immuni.2012.01.016. Epub 2012 Mar 15.

50.

β5t-containing thymoproteasome: specific expression in thymic cortical epithelial cells and role in positive selection of CD8+ T cells.

Takahama Y, Takada K, Murata S, Tanaka K.

Curr Opin Immunol. 2012 Feb;24(1):92-8. doi: 10.1016/j.coi.2012.01.006. Epub 2012 Jan 27. Review.

PMID:
22285892

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