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Items: 1 to 50 of 313

1.

Glucocorticoid-loaded liposomes induce a pro-resolution phenotype in human primary macrophages to support chronic wound healing.

Gauthier A, Fisch A, Seuwen K, Baumgarten B, Ruffner H, Aebi A, Rausch M, Kiessling F, Bartneck M, Weiskirchen R, Tacke F, Storm G, Lammers T, Ludwig MG.

Biomaterials. 2018 Apr 5. pii: S0142-9612(18)30245-X. doi: 10.1016/j.biomaterials.2018.04.006. [Epub ahead of print]

PMID:
29650255
2.

Elevated Serum Levels of Mixed Lineage Kinase Domain-Like Protein Predict Survival of Patients during Intensive Care Unit Treatment.

Vucur M, Roderburg C, Kaiser L, Schneider AT, Roy S, Loosen SH, Luedde M, Trautwein C, Koch A, Tacke F, Luedde T.

Dis Markers. 2018 Feb 11;2018:1983421. doi: 10.1155/2018/1983421. eCollection 2018.

3.

New Insights on the Role of Kupffer Cells in Liver Transplantation.

Tacke F.

Transplantation. 2018 Jun;102(6):896-897. doi: 10.1097/TP.0000000000002193. No abstract available.

PMID:
29570168
4.

Liver inflammation and regeneration in drug-induced liver injury: sex matters!

Sutti S, Tacke F.

Clin Sci (Lond). 2018 Mar 15;132(5):609-613. doi: 10.1042/CS20171313. Print 2018 Mar 15.

PMID:
29545336
5.

«The times they are a'changin'» - Positioning the European Association for the Study of the Liver in the changing landscape of hepatology.

Karlsen TH, Tacke F.

J Hepatol. 2018 May;68(5):873-875. doi: 10.1016/j.jhep.2018.02.001. Epub 2018 Mar 2. No abstract available.

PMID:
29500035
6.

Dynamic plasticity of macrophage functions in diseased liver.

Ritz T, Krenkel O, Tacke F.

Cell Immunol. 2017 Dec 20. pii: S0008-8749(17)30233-2. doi: 10.1016/j.cellimm.2017.12.007. [Epub ahead of print]

PMID:
29454647
7.

Cenicriviroc for the treatment of non-alcoholic steatohepatitis and liver fibrosis.

Tacke F.

Expert Opin Investig Drugs. 2018 Mar;27(3):301-311. doi: 10.1080/13543784.2018.1442436. Epub 2018 Feb 22. Review.

PMID:
29448843
8.

The Janus-like Face of IL-4Rα in Macrophages during Liver Fibrosis.

Ritz T, Tacke F.

EBioMedicine. 2018 Mar;29:7-8. doi: 10.1016/j.ebiom.2018.02.004. Epub 2018 Feb 5. No abstract available.

9.

Do we still need pharmacological stress ulcer prophylaxis at the ICU?

Buendgens L, Tacke F.

J Thorac Dis. 2017 Nov;9(11):4201-4204. doi: 10.21037/jtd.2017.09.121. No abstract available.

10.

Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formation.

Brehs M, Pötgens AJG, Steitz J, Thewes K, Schwarz J, Conibear AC, Bartneck M, Tacke F, Becker CFW.

Sci Rep. 2017 Dec 14;7(1):17592. doi: 10.1038/s41598-017-17627-0.

11.

CEA but not CA19-9 is an independent prognostic factor in patients undergoing resection of cholangiocarcinoma.

Loosen SH, Roderburg C, Kauertz KL, Koch A, Vucur M, Schneider AT, Binnebösel M, Ulmer TF, Lurje G, Schoening W, Tacke F, Trautwein C, Longerich T, Dejong CH, Neumann UP, Luedde T.

Sci Rep. 2017 Dec 5;7(1):16975. doi: 10.1038/s41598-017-17175-7.

12.

[S2k Guideline Gastrointestinal Bleeding - Guideline of the German Society of Gastroenterology DGVS].

Götz M, Anders M, Biecker E, Bojarski C, Braun G, Brechmann T, Dechêne A, Dollinger M, Gawaz M, Kiesslich R, Schilling D, Tacke F, Zipprich A, Trebicka J; Deutsche Gesellschaft für Gastroenterologie; Verdauungs- und Stoffwechselkrankheiten (DGVS) (federführend); Deutschen Morbus Crohn und Colitis ulcerosa Vereinigung (DCCV); Deutsche Röntgengesellschaft (DRG); Deutsche Gesellschaft für interventionelle Radiologie (DeGiR); Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie (DGAV) und Chirurgische Arbeitsgemeinschaft für Endoskopie und Sonographie (CAES) der DGAV; Deutsche Gesellschaft für Internistische Intensivmedizin (DGIIN); Deutsche Gesellschaft für Innere Medizin (DGIM); Deutsche Gesellschaft für Kardiologie (DGK); Akademie für Ethik in der Medizin (AEM); Gesellschaft für Thrombose- und Hämostaseforschung (GTH); Collaborators:.

Z Gastroenterol. 2017 Sep;55(9):883-936. doi: 10.1055/s-0043-116856. Epub 2017 Sep 12. German. No abstract available.

13.

Growth Differentiation Factor-15 Is a Predictor of Mortality in Critically Ill Patients with Sepsis.

Buendgens L, Yagmur E, Bruensing J, Herbers U, Baeck C, Trautwein C, Koch A, Tacke F.

Dis Markers. 2017;2017:5271203. doi: 10.1155/2017/5271203. Epub 2017 Oct 18.

14.

Fibrosis imaging: Current concepts and future directions.

Baues M, Dasgupta A, Ehling J, Prakash J, Boor P, Tacke F, Kiessling F, Lammers T.

Adv Drug Deliv Rev. 2017 Nov 1;121:9-26. doi: 10.1016/j.addr.2017.10.013. Epub 2017 Nov 20. Review.

PMID:
29108860
15.

Combining GP73 with liver stiffness measurements: A proof-of-concept for non-invasive fibrosis assessment in antiviral-naïve HBV patients.

Weiskirchen R, Tacke F.

Liver Int. 2017 Nov;37(11):1605-1607. doi: 10.1111/liv.13563. No abstract available.

PMID:
29065256
16.

Hypothermic oxygenated machine perfusion (HOPE) for orthotopic liver transplantation of human liver allografts from extended criteria donors (ECD) in donation after brain death (DBD): a prospective multicentre randomised controlled trial (HOPE ECD-DBD).

Czigany Z, Schöning W, Ulmer TF, Bednarsch J, Amygdalos I, Cramer T, Rogiers X, Popescu I, Botea F, Froněk J, Kroy D, Koch A, Tacke F, Trautwein C, Tolba RH, Hein M, Koek GH, Dejong CHC, Neumann UP, Lurje G.

BMJ Open. 2017 Oct 10;7(10):e017558. doi: 10.1136/bmjopen-2017-017558.

17.

Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis.

Krenkel O, Puengel T, Govaere O, Abdallah AT, Mossanen JC, Kohlhepp M, Liepelt A, Lefebvre E, Luedde T, Hellerbrand C, Weiskirchen R, Longerich T, Costa IG, Anstee QM, Trautwein C, Tacke F.

Hepatology. 2018 Apr;67(4):1270-1283. doi: 10.1002/hep.29544. Epub 2018 Feb 19.

PMID:
28940700
18.

Differential impact of the dual CCR2/CCR5 inhibitor cenicriviroc on migration of monocyte and lymphocyte subsets in acute liver injury.

Puengel T, Krenkel O, Kohlhepp M, Lefebvre E, Luedde T, Trautwein C, Tacke F.

PLoS One. 2017 Sep 14;12(9):e0184694. doi: 10.1371/journal.pone.0184694. eCollection 2017.

19.

Macrophages in Nonalcoholic Fatty Liver Disease: A Role Model of Pathogenic Immunometabolism.

Krenkel O, Tacke F.

Semin Liver Dis. 2017 Aug;37(3):189-197. doi: 10.1055/s-0037-1604480. Epub 2017 Aug 28. No abstract available.

PMID:
28847030
20.

Isolation and Culture of Primary Murine Hepatic Stellate Cells.

Weiskirchen S, Tag CG, Sauer-Lehnen S, Tacke F, Weiskirchen R.

Methods Mol Biol. 2017;1627:165-191. doi: 10.1007/978-1-4939-7113-8_11.

PMID:
28836201
21.

A randomized, placebo-controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis.

Friedman SL, Ratziu V, Harrison SA, Abdelmalek MF, Aithal GP, Caballeria J, Francque S, Farrell G, Kowdley KV, Craxi A, Simon K, Fischer L, Melchor-Khan L, Vest J, Wiens BL, Vig P, Seyedkazemi S, Goodman Z, Wong VW, Loomba R, Tacke F, Sanyal A, Lefebvre E.

Hepatology. 2018 May;67(5):1754-1767. doi: 10.1002/hep.29477. Epub 2018 Jan 29.

22.

Immunomodulatory Therapy of Inflammatory Liver Disease Using Selectin-Binding Glycopolymers.

Bartneck M, Schlößer CT, Barz M, Zentel R, Trautwein C, Lammers T, Tacke F.

ACS Nano. 2017 Oct 24;11(10):9689-9700. doi: 10.1021/acsnano.7b04630. Epub 2017 Aug 25.

PMID:
28829572
23.

Elevated Soluble Urokinase Plasminogen Activator Receptor and Proenkephalin Serum Levels Predict the Development of Acute Kidney Injury after Cardiac Surgery.

Mossanen JC, Pracht J, Jansen TU, Buendgens L, Stoppe C, Goetzenich A, Struck J, Autschbach R, Marx G, Tacke F.

Int J Mol Sci. 2017 Jul 31;18(8). pii: E1662. doi: 10.3390/ijms18081662.

24.

[Invasive Candida infections in liver cirrhosis].

Koch A, Tacke F.

Med Klin Intensivmed Notfmed. 2018 Mar;113(2):139-140. doi: 10.1007/s00063-017-0328-3. Epub 2017 Jul 26. German. No abstract available.

PMID:
28748279
25.

CX3CR1 modulates the anti-inflammatory activity of hepatic dendritic cells in response to acute liver injury.

Sutti S, Heymann F, Bruzzì S, Peusquens J, Trautwein C, Albano E, Tacke F.

Clin Sci (Lond). 2017 Jul 24. pii: CS20171025. doi: 10.1042/CS20171025. [Epub ahead of print]

PMID:
28739980
26.

A not so easy genotype-striking regional differences in SOF/RBV treatment responses in HCV GT2.

Tacke F, Mauss S.

Liver Int. 2017 Aug;37(8):1253-1254. doi: 10.1111/liv.13447. No abstract available.

PMID:
28710821
27.

Elevated levels of circulating osteopontin are associated with a poor survival after resection of cholangiocarcinoma.

Loosen SH, Roderburg C, Kauertz KL, Pombeiro I, Leyh C, Benz F, Vucur M, Longerich T, Koch A, Braunschweig T, Ulmer TF, Heidenhain C, Tacke F, Binnebösel M, Schmeding M, Trautwein C, Neumann UP, Luedde T.

J Hepatol. 2017 Oct;67(4):749-757. doi: 10.1016/j.jhep.2017.06.020. Epub 2017 Jun 29.

PMID:
28668580
28.

miR-1224 inhibits cell proliferation in acute liver failure by targeting the antiapoptotic gene Nfib.

Roy S, Bantel H, Wandrer F, Schneider AT, Gautheron J, Vucur M, Tacke F, Trautwein C, Luedde T, Roderburg C.

J Hepatol. 2017 Nov;67(5):966-978. doi: 10.1016/j.jhep.2017.06.007. Epub 2017 Jun 21.

PMID:
28645739
29.

Targeting CCl4 -induced liver fibrosis by RNA interference-mediated inhibition of cyclin E1 in mice.

Bangen JM, Hammerich L, Sonntag R, Baues M, Haas U, Lambertz D, Longerich T, Lammers T, Tacke F, Trautwein C, Liedtke C.

Hepatology. 2017 Oct;66(4):1242-1257. doi: 10.1002/hep.29275. Epub 2017 Aug 26.

PMID:
28520165
30.

Repair macrophages in acute liver failure.

Puengel T, Tacke F.

Gut. 2018 Feb;67(2):202-203. doi: 10.1136/gutjnl-2017-314245. Epub 2017 May 8. No abstract available.

PMID:
28483781
31.

[Acute liver failure].

Koch A, Trautwein C, Tacke F.

Med Klin Intensivmed Notfmed. 2017 May;112(4):371-381. doi: 10.1007/s00063-017-0282-0. Epub 2017 Apr 25. German.

PMID:
28444411
32.

Management of hepatitis C virus infection in the Asia-Pacific region: an update.

Lim SG, Aghemo A, Chen PJ, Dan YY, Gane E, Gani R, Gish RG, Guan R, Jia JD, Lim K, Piratvisuth T, Shah S, Shiffman ML, Tacke F, Tan SS, Tanwandee T, Win KM, Yurdaydin C.

Lancet Gastroenterol Hepatol. 2017 Jan;2(1):52-62. doi: 10.1016/S2468-1253(16)30080-2. Epub 2016 Dec 10. Review.

PMID:
28404015
33.

Selection of the highly replicative and partially multidrug resistant rtS78T HBV polymerase mutation during TDF-ETV combination therapy.

Shirvani-Dastgerdi E, Winer BY, Celià-Terrassa T, Kang Y, Tabernero D, Yagmur E, Rodríguez-Frías F, Gregori J, Luedde T, Trautwein C, Ploss A, Tacke F.

J Hepatol. 2017 Aug;67(2):246-254. doi: 10.1016/j.jhep.2017.03.027. Epub 2017 Apr 7.

PMID:
28392234
34.

GLP-1 Levels Predict Mortality in Patients with Critical Illness as Well as End-Stage Renal Disease.

Lebherz C, Schlieper G, Möllmann J, Kahles F, Schwarz M, Brünsing J, Dimkovic N, Koch A, Trautwein C, Flöge J, Marx N, Tacke F, Lehrke M.

Am J Med. 2017 Jul;130(7):833-841.e3. doi: 10.1016/j.amjmed.2017.03.010. Epub 2017 Mar 31.

PMID:
28366423
35.

C-terminal proendothelin-1 (CT-proET-1) is associated with organ failure and predicts mortality in critically ill patients.

Buendgens L, Yagmur E, Bruensing J, Herbers U, Baeck C, Trautwein C, Koch A, Tacke F.

J Intensive Care. 2017 Mar 20;5:25. doi: 10.1186/s40560-017-0219-y. eCollection 2017.

36.

Liver macrophages in tissue homeostasis and disease.

Krenkel O, Tacke F.

Nat Rev Immunol. 2017 May;17(5):306-321. doi: 10.1038/nri.2017.11. Epub 2017 Mar 20. Review.

PMID:
28317925
37.

SFB/TRR 57 Aachen/Bonn: Organfibrose – von den Mechanismen der Schädigung zur Beeinflussung der Krankheit.

Trautwein C, Tacke F.

Z Gastroenterol. 2017 Mar;55(3):310-312. doi: 10.1055/s-0042-123865. Epub 2017 Mar 13. German. No abstract available.

PMID:
28288503
38.

Targeting hepatic macrophages to treat liver diseases.

Tacke F.

J Hepatol. 2017 Jun;66(6):1300-1312. doi: 10.1016/j.jhep.2017.02.026. Epub 2017 Mar 4. Review.

PMID:
28267621
39.

Interleukin-33 in the pathogenesis of liver fibrosis: alarming ILC2 and hepatic stellate cells.

Weiskirchen R, Tacke F.

Cell Mol Immunol. 2017 Feb;14(2):143-145. doi: 10.1038/cmi.2016.62. Epub 2016 Dec 26. No abstract available.

40.

RIPK1 Suppresses a TRAF2-Dependent Pathway to Liver Cancer.

Schneider AT, Gautheron J, Feoktistova M, Roderburg C, Loosen SH, Roy S, Benz F, Schemmer P, Büchler MW, Nachbur U, Neumann UP, Tolba R, Luedde M, Zucman-Rossi J, Panayotova-Dimitrova D, Leverkus M, Preisinger C, Tacke F, Trautwein C, Longerich T, Vucur M, Luedde T.

Cancer Cell. 2017 Jan 9;31(1):94-109. doi: 10.1016/j.ccell.2016.11.009. Epub 2016 Dec 22.

41.

From NAFLD to HCC: Is IL-17 the crucial link?

Hatting M, Tacke F.

Hepatology. 2017 Feb;65(2):739-741. doi: 10.1002/hep.28934. Epub 2016 Dec 24. No abstract available.

PMID:
28012256
42.

Polymeric Selectin Ligands Mimicking Complex Carbohydrates: From Selectin Binders to Modifiers of Macrophage Migration.

Moog KE, Barz M, Bartneck M, Beceren-Braun F, Mohr N, Wu Z, Braun L, Dernedde J, Liehn EA, Tacke F, Lammers T, Kunz H, Zentel R.

Angew Chem Int Ed Engl. 2017 Jan 24;56(5):1416-1421. doi: 10.1002/anie.201610395. Epub 2016 Dec 22.

PMID:
28005299
43.

One-Step Fabrication of Biocompatible Multifaceted Nanocomposite Gels and Nanolayers.

Topuz F, Bartneck M, Pan Y, Tacke F.

Biomacromolecules. 2017 Feb 13;18(2):386-397. doi: 10.1021/acs.biomac.6b01483. Epub 2017 Jan 3.

PMID:
27977144
44.

Liver - guardian, modifier and target of sepsis.

Strnad P, Tacke F, Koch A, Trautwein C.

Nat Rev Gastroenterol Hepatol. 2017 Jan;14(1):55-66. doi: 10.1038/nrgastro.2016.168. Epub 2016 Dec 7. Review.

PMID:
27924081
45.

The PDE4 inhibitor roflumilast reduces weight gain by increasing energy expenditure and leads to improved glucose metabolism.

Möllmann J, Kahles F, Lebherz C, Kappel B, Baeck C, Tacke F, Werner C, Federici M, Marx N, Lehrke M.

Diabetes Obes Metab. 2017 Apr;19(4):496-508. doi: 10.1111/dom.12839. Epub 2017 Feb 22.

PMID:
27917591
46.

Elevated Omentin Serum Levels Predict Long-Term Survival in Critically Ill Patients.

Luedde M, Benz F, Niedeggen J, Vucur M, Hippe HJ, Spehlmann ME, Schueller F, Loosen S, Frey N, Trautwein C, Koch A, Luedde T, Tacke F, Roderburg C.

Dis Markers. 2016;2016:3149243. Epub 2016 Oct 27.

47.

Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles.

Ergen C, Heymann F, Al Rawashdeh W, Gremse F, Bartneck M, Panzer U, Pola R, Pechar M, Storm G, Mohr N, Barz M, Zentel R, Kiessling F, Trautwein C, Lammers T, Tacke F.

Biomaterials. 2017 Jan;114:106-120. doi: 10.1016/j.biomaterials.2016.11.009. Epub 2016 Nov 9.

PMID:
27855336
48.
49.

Chemokine (C-C motif) receptor 2-positive monocytes aggravate the early phase of acetaminophen-induced acute liver injury.

Mossanen JC, Krenkel O, Ergen C, Govaere O, Liepelt A, Puengel T, Heymann F, Kalthoff S, Lefebvre E, Eulberg D, Luedde T, Marx G, Strassburg CP, Roskams T, Trautwein C, Tacke F.

Hepatology. 2016 Nov;64(5):1667-1682. doi: 10.1002/hep.28682. Epub 2016 Jul 22.

PMID:
27302828
50.

Treatment for hepatitis B in patients with drug resistance.

Tacke F, Kroy DC.

Ann Transl Med. 2016 Sep;4(18):334. Review.

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