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Items: 1 to 50 of 214

1.

APOE genotype modifies the association between central arterial stiffening and cognition in older adults.

Cambronero FE, Liu D, Neal JE, Moore EE, Gifford KA, Terry JG, Nair S, Pechman KR, Osborn KE, Hohman TJ, Bell SP, Sweatt JD, Wang TJ, Beckman JA, Carr JJ, Jefferson AL.

Neurobiol Aging. 2018 Feb 20;67:120-127. doi: 10.1016/j.neurobiolaging.2018.02.009. [Epub ahead of print]

PMID:
29656011
2.

Autosomal dominant retinitis pigmentosa rhodopsin mutant Q344X drives specific alterations in chromatin complex gene transcription.

Bales KL, Ianov L, Kennedy AJ, Sweatt JD, Gross AK.

Mol Vis. 2018 Feb 15;24:153-164. eCollection 2018.

3.

Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment.

Ianov L, De Both M, Chawla MK, Rani A, Kennedy AJ, Piras I, Day JJ, Siniard A, Kumar A, Sweatt JD, Barnes CA, Huentelman MJ, Foster TC.

Front Aging Neurosci. 2017 Dec 8;9:383. doi: 10.3389/fnagi.2017.00383. eCollection 2017.

4.

Layered-up regulation in the developing brain.

Sweatt JD.

Nature. 2017 Nov 23;551(7681):448-449. doi: 10.1038/d41586-017-07269-7. No abstract available.

PMID:
29168827
5.

Experience-dependent epigenomic reorganization in the hippocampus.

Duke CG, Kennedy AJ, Gavin CF, Day JJ, Sweatt JD.

Learn Mem. 2017 Jun 15;24(7):278-288. doi: 10.1101/lm.045112.117. Print 2017 Jul.

PMID:
28620075
6.

Neural plasticity and behavior - sixty years of conceptual advances.

Sweatt JD.

J Neurochem. 2016 Oct;139 Suppl 2:179-199. doi: 10.1111/jnc.13580. Epub 2016 Mar 10. Review.

7.

An epigenomics approach to individual differences and its translation to neuropsychiatric conditions.

Sweatt JD, Tamminga CA.

Dialogues Clin Neurosci. 2016 Sep;18(3):289-298. Review.

8.

Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function.

Kennedy AJ, Rahn EJ, Paulukaitis BS, Savell KE, Kordasiewicz HB, Wang J, Lewis JW, Posey J, Strange SK, Guzman-Karlsson MC, Phillips SE, Decker K, Motley ST, Swayze EE, Ecker DJ, Michael TP, Day JJ, Sweatt JD.

Cell Rep. 2016 Sep 6;16(10):2666-2685. doi: 10.1016/j.celrep.2016.08.004. Epub 2016 Aug 25.

9.

Dynamic DNA methylation regulates neuronal intrinsic membrane excitability.

Meadows JP, Guzman-Karlsson MC, Phillips S, Brown JA, Strange SK, Sweatt JD, Hablitz JJ.

Sci Signal. 2016 Aug 23;9(442):ra83. doi: 10.1126/scisignal.aaf5642.

10.

GENE EXPRESSION. Chromatin controls behavior.

Sweatt JD.

Science. 2016 Jul 15;353(6296):218-9. doi: 10.1126/science.aah4055. No abstract available.

PMID:
27418488
11.

Extra-coding RNAs regulate neuronal DNA methylation dynamics.

Savell KE, Gallus NV, Simon RC, Brown JA, Revanna JS, Osborn MK, Song EY, O'Malley JJ, Stackhouse CT, Norvil A, Gowher H, Sweatt JD, Day JJ.

Nat Commun. 2016 Jul 7;7:12091. doi: 10.1038/ncomms12091.

12.

The molecular neurobiology of the sleep-deprived, fuzzy brain.

Sweatt JD, Hawkins KE.

Sci Signal. 2016 Apr 26;9(425):fs7. doi: 10.1126/scisignal.aaf6196. Review.

PMID:
27117249
13.

Drugging the methylome: DNA methylation and memory.

Kennedy AJ, Sweatt JD.

Crit Rev Biochem Mol Biol. 2016 May-Jun;51(3):185-94. doi: 10.3109/10409238.2016.1150958. Epub 2016 Feb 25. Review.

14.

Dynamic DNA methylation controls glutamate receptor trafficking and synaptic scaling.

Sweatt JD.

J Neurochem. 2016 May;137(3):312-30. doi: 10.1111/jnc.13564. Epub 2016 Mar 3. Review.

15.

Obesity Weighs down Memory through a Mechanism Involving the Neuroepigenetic Dysregulation of Sirt1.

Heyward FD, Gilliam D, Coleman MA, Gavin CF, Wang J, Kaas G, Trieu R, Lewis J, Moulden J, Sweatt JD.

J Neurosci. 2016 Jan 27;36(4):1324-35. doi: 10.1523/JNEUROSCI.1934-15.2016.

16.

Tet1 Oxidase Regulates Neuronal Gene Transcription, Active DNA Hydroxy-methylation, Object Location Memory, and Threat Recognition Memory.

Kumar D, Aggarwal M, Kaas GA, Lewis J, Wang J, Ross DL, Zhong C, Kennedy A, Song H, Sweatt JD.

Neuroepigenetics. 2015 Oct 1;4:12-27.

17.

Memory-Associated Dynamic Regulation of the "Stable" Core of the Chromatin Particle.

Zovkic IB, Sweatt JD.

Neuron. 2015 Jul 1;87(1):1-4. doi: 10.1016/j.neuron.2015.06.025.

18.

DNA methylation regulates neuronal glutamatergic synaptic scaling.

Meadows JP, Guzman-Karlsson MC, Phillips S, Holleman C, Posey JL, Day JJ, Hablitz JJ, Sweatt JD.

Sci Signal. 2015 Jun 23;8(382):ra61. doi: 10.1126/scisignal.aab0715.

19.

DNA methylation regulates neurophysiological spatial representation in memory formation.

Roth ED, Roth TL, Money KM, SenGupta S, Eason DE, Sweatt JD.

Neuroepigenetics. 2015 Apr 1;2:1-8.

20.

Pharmacological Selectivity Within Class I Histone Deacetylases Predicts Effects on Synaptic Function and Memory Rescue.

Rumbaugh G, Sillivan SE, Ozkan ED, Rojas CS, Hubbs CR, Aceti M, Kilgore M, Kudugunti S, Puthanveettil SV, Sweatt JD, Rusche J, Miller CA.

Neuropsychopharmacology. 2015 Sep;40(10):2307-16. doi: 10.1038/npp.2015.93. Epub 2015 Apr 3.

21.

DNA Methylation in Memory Formation: Emerging Insights.

Heyward FD, Sweatt JD.

Neuroscientist. 2015 Oct;21(5):475-89. doi: 10.1177/1073858415579635. Epub 2015 Apr 1. Review.

22.

Behavioral and electrophysiological characterization of Dyt1 heterozygous knockout mice.

Yokoi F, Chen HX, Dang MT, Cheetham CC, Campbell SL, Roper SN, Sweatt JD, Li Y.

PLoS One. 2015 Mar 23;10(3):e0120916. doi: 10.1371/journal.pone.0120916. eCollection 2015. Erratum in: PLoS One. 2015;10(4):e0126539.

23.

Pitt-Hopkins Mouse Model has Altered Particular Gastrointestinal Transits In Vivo.

Grubišić V, Kennedy AJ, Sweatt JD, Parpura V.

Autism Res. 2015 Oct;8(5):629-33. doi: 10.1002/aur.1467. Epub 2015 Feb 26.

24.

DNA methylation and its implications and accessibility for neuropsychiatric therapeutics.

Day JJ, Kennedy AJ, Sweatt JD.

Annu Rev Pharmacol Toxicol. 2015;55:591-611. doi: 10.1146/annurev-pharmtox-010814-124527. Epub 2014 Oct 17. Review.

25.

Aging and energetics' 'Top 40' future research opportunities 2010-2013.

Allison DB, Antoine LH, Ballinger SW, Bamman MM, Biga P, Darley-Usmar VM, Fisher G, Gohlke JM, Halade GV, Hartman JL, Hunter GR, Messina JL, Nagy TR, Plaisance EP, Powell ML, Roth KA, Sandel MW, Schwartz TS, Smith DL, Sweatt JD, Tollefsbol TO, Watts SA, Yang Y, Zhang J, Austad SN.

F1000Res. 2014 Sep 12;3:219. doi: 10.12688/f1000research.5212.1. eCollection 2014. Review.

26.

Histone H2A.Z subunit exchange controls consolidation of recent and remote memory.

Zovkic IB, Paulukaitis BS, Day JJ, Etikala DM, Sweatt JD.

Nature. 2014 Nov 27;515(7528):582-6. doi: 10.1038/nature13707. Epub 2014 Sep 14.

27.

Transcriptional and epigenetic regulation of Hebbian and non-Hebbian plasticity.

Guzman-Karlsson MC, Meadows JP, Gavin CF, Hablitz JJ, Sweatt JD.

Neuropharmacology. 2014 May;80:3-17. doi: 10.1016/j.neuropharm.2014.01.001. Epub 2014 Jan 10. Review.

28.

The emerging field of neuroepigenetics.

Sweatt JD.

Neuron. 2013 Oct 30;80(3):624-32. doi: 10.1016/j.neuron.2013.10.023. Review.

29.

The role of the Gadd45 family in the nervous system: a focus on neurodevelopment, neuronal injury, and cognitive neuroepigenetics.

Sultan FA, Sweatt JD.

Adv Exp Med Biol. 2013;793:81-119. doi: 10.1007/978-1-4614-8289-5_6. Review.

PMID:
24104475
30.

TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation.

Kaas GA, Zhong C, Eason DE, Ross DL, Vachhani RV, Ming GL, King JR, Song H, Sweatt JD.

Neuron. 2013 Sep 18;79(6):1086-93. doi: 10.1016/j.neuron.2013.08.032.

31.

DNA methylation regulates associative reward learning.

Day JJ, Childs D, Guzman-Karlsson MC, Kibe M, Moulden J, Song E, Tahir A, Sweatt JD.

Nat Neurosci. 2013 Oct;16(10):1445-52. doi: 10.1038/nn.3504. Epub 2013 Aug 25.

32.

Pre-synaptic release deficits in a DYT1 dystonia mouse model.

Yokoi F, Cheetham CC, Campbell SL, Sweatt JD, Li Y.

PLoS One. 2013 Aug 13;8(8):e72491. doi: 10.1371/journal.pone.0072491. eCollection 2013.

33.

Interindividual Variability in Stress Susceptibility: A Role for Epigenetic Mechanisms in PTSD.

Zovkic IB, Meadows JP, Kaas GA, Sweatt JD.

Front Psychiatry. 2013 Jun 26;4:60. doi: 10.3389/fpsyt.2013.00060. eCollection 2013.

34.

Pitt-Hopkins Syndrome: intellectual disability due to loss of TCF4-regulated gene transcription.

Sweatt JD.

Exp Mol Med. 2013 May 3;45:e21. doi: 10.1038/emm.2013.32. Review.

35.

Disruption of neocortical histone H3 homeostasis by soluble Aβ: implications for Alzheimer's disease.

Lithner CU, Lacor PN, Zhao WQ, Mustafiz T, Klein WL, Sweatt JD, Hernandez CM.

Neurobiol Aging. 2013 Sep;34(9):2081-90. doi: 10.1016/j.neurobiolaging.2012.12.028. Epub 2013 Apr 9.

PMID:
23582659
36.

Epigenetic regulation of memory formation and maintenance.

Zovkic IB, Guzman-Karlsson MC, Sweatt JD.

Learn Mem. 2013 Jan 15;20(2):61-74. doi: 10.1101/lm.026575.112. Review.

37.

Genetic deletion of Gadd45b, a regulator of active DNA demethylation, enhances long-term memory and synaptic plasticity.

Sultan FA, Wang J, Tront J, Liebermann DA, Sweatt JD.

J Neurosci. 2012 Nov 28;32(48):17059-66. doi: 10.1523/JNEUROSCI.1747-12.2012.

38.

Protease-activated receptor-1 modulates hippocampal memory formation and synaptic plasticity.

Almonte AG, Qadri LH, Sultan FA, Watson JA, Mount DJ, Rumbaugh G, Sweatt JD.

J Neurochem. 2013 Jan;124(1):109-22. doi: 10.1111/jnc.12075. Epub 2012 Nov 21.

39.

Epigenetic mechanisms in learned fear: implications for PTSD.

Zovkic IB, Sweatt JD.

Neuropsychopharmacology. 2013 Jan;38(1):77-93. doi: 10.1038/npp.2012.79. Epub 2012 Jun 13. Review.

40.

Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression.

Heyward FD, Walton RG, Carle MS, Coleman MA, Garvey WT, Sweatt JD.

Neurobiol Learn Mem. 2012 Jul;98(1):25-32. doi: 10.1016/j.nlm.2012.04.005. Epub 2012 Apr 21.

41.

Enhanced hippocampal long-term potentiation and fear memory in Btbd9 mutant mice.

DeAndrade MP, Zhang L, Doroodchi A, Yokoi F, Cheetham CC, Chen HX, Roper SN, Sweatt JD, Li Y.

PLoS One. 2012;7(4):e35518. doi: 10.1371/journal.pone.0035518. Epub 2012 Apr 19.

42.

Mechanisms of age-related cognitive change and targets for intervention: epigenetics.

Kosik KS, Rapp PR, Raz N, Small SA, Sweatt JD, Tsai LH.

J Gerontol A Biol Sci Med Sci. 2012 Jun;67(7):741-6. doi: 10.1093/gerona/gls110. Epub 2012 Apr 20. Review.

43.

Serine proteases, serine protease inhibitors, and protease-activated receptors: roles in synaptic function and behavior.

Almonte AG, Sweatt JD.

Brain Res. 2011 Aug 17;1407:107-22. doi: 10.1016/j.brainres.2011.06.042. Epub 2011 Jun 24. Review.

44.

Epigenetic mechanisms in cognition.

Day JJ, Sweatt JD.

Neuron. 2011 Jun 9;70(5):813-29. doi: 10.1016/j.neuron.2011.05.019. Review.

45.

Behavioral epigenetics.

Lester BM, Tronick E, Nestler E, Abel T, Kosofsky B, Kuzawa CW, Marsit CJ, Maze I, Meaney MJ, Monteggia LM, Reul JM, Skuse DH, Sweatt JD, Wood MA.

Ann N Y Acad Sci. 2011 May;1226:14-33. doi: 10.1111/j.1749-6632.2011.06037.x.

46.

Epigenetic treatments for cognitive impairments.

Day JJ, Sweatt JD.

Neuropsychopharmacology. 2012 Jan;37(1):247-60. doi: 10.1038/npp.2011.85. Epub 2011 May 18. Review.

47.

Neuroscience. Creating stable memories.

Sweatt JD.

Science. 2011 Feb 18;331(6019):869-70. doi: 10.1126/science.1202283. No abstract available.

PMID:
21330525
48.

Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder.

Roth TL, Zoladz PR, Sweatt JD, Diamond DM.

J Psychiatr Res. 2011 Jul;45(7):919-26. doi: 10.1016/j.jpsychires.2011.01.013. Epub 2011 Feb 9.

49.

Cognitive neuroepigenetics: a role for epigenetic mechanisms in learning and memory.

Day JJ, Sweatt JD.

Neurobiol Learn Mem. 2011 Jul;96(1):2-12. doi: 10.1016/j.nlm.2010.12.008. Epub 2010 Dec 30. Review.

50.

Epigenetic modifications in neurons are essential for formation and storage of behavioral memory.

Day JJ, Sweatt JD.

Neuropsychopharmacology. 2011 Jan;36(1):357-8. doi: 10.1038/npp.2010.125. No abstract available.

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