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Items: 20

2.

Loss of tyrosine phosphatase-dependent inhibition promotes activation of tyrosine kinase c-Src in detached pancreatic cells.

Connelly SF, Isley BA, Baker CH, Gallick GE, Summy JM.

Mol Carcinog. 2010 Dec;49(12):1007-21. doi: 10.1002/mc.20684.

3.

Development and characterization of gemcitabine-resistant pancreatic tumor cells.

Shah AN, Summy JM, Zhang J, Park SI, Parikh NU, Gallick GE.

Ann Surg Oncol. 2007 Dec;14(12):3629-37. Epub 2007 Oct 2.

PMID:
17909916
4.

AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts.

Zhang J, Park SI, Artime MC, Summy JM, Shah AN, Bomser JA, Dorfleutner A, Flynn DC, Gallick GE.

J Clin Invest. 2007 Oct;117(10):2962-73.

5.

Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells.

Trevino JG, Gray MJ, Nawrocki ST, Summy JM, Lesslie DP, Evans DB, Sawyer TK, Shakespeare WC, Watowich SS, Chiao PJ, McConkey DJ, Gallick GE.

Angiogenesis. 2006;9(2):101-10. Epub 2006 Jul 27.

PMID:
16871430
6.

SRC inhibitors as potential therapeutic agents for human cancers.

Trevino JG, Summy JM, Gallick GE.

Mini Rev Med Chem. 2006 Jun;6(6):681-7. Review.

PMID:
16787379
7.

Inhibition of PDGFR phosphorylation and Src and Akt activity by GN963 leads to therapy of human pancreatic cancer growing orthotopically in nude mice.

Baker CH, Trevino JG, Summy JM, Zhang F, Caron A, Nesbit M, Gallick GE, Fidler IJ.

Int J Oncol. 2006 Jul;29(1):125-38.

PMID:
16773192
8.

Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases.

Lesslie DP, Summy JM, Parikh NU, Fan F, Trevino JG, Sawyer TK, Metcalf CA, Shakespeare WC, Hicklin DJ, Ellis LM, Gallick GE.

Br J Cancer. 2006 Jun 5;94(11):1710-7.

9.

Treatment for advanced tumors: SRC reclaims center stage.

Summy JM, Gallick GE.

Clin Cancer Res. 2006 Mar 1;12(5):1398-401. Review. No abstract available.

10.

Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model.

Trevino JG, Summy JM, Lesslie DP, Parikh NU, Hong DS, Lee FY, Donato NJ, Abbruzzese JL, Baker CH, Gallick GE.

Am J Pathol. 2006 Mar;168(3):962-72.

11.

AP23846, a novel and highly potent Src family kinase inhibitor, reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines and abrogates downstream angiogenic processes.

Summy JM, Trevino JG, Lesslie DP, Baker CH, Shakespeare WC, Wang Y, Sundaramoorthi R, Metcalf CA 3rd, Keats JA, Sawyer TK, Gallick GE.

Mol Cancer Ther. 2005 Dec;4(12):1900-11.

12.
13.

Expression and activity of SRC regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis.

Trevino JG, Summy JM, Gray MJ, Nilsson MB, Lesslie DP, Baker CH, Gallick GE.

Cancer Res. 2005 Aug 15;65(16):7214-22.

14.

Src family kinases in tumor progression and metastasis.

Summy JM, Gallick GE.

Cancer Metastasis Rev. 2003 Dec;22(4):337-58. Review.

PMID:
12884910
15.

The SH4-Unique-SH3-SH2 domains dictate specificity in signaling that differentiate c-Yes from c-Src.

Summy JM, Qian Y, Jiang BH, Guappone-Koay A, Gatesman A, Shi X, Flynn DC.

J Cell Sci. 2003 Jun 15;116(Pt 12):2585-98. Epub 2003 May 6.

16.

Specificity in signaling by c-Yes.

Summy JM, Sudol M, Eck MJ, Monteiro AN, Gatesman A, Flynn DC.

Front Biosci. 2003 Jan 1;8:s185-205. Review.

PMID:
12456296
17.

Src activation regulates anoikis in human colon tumor cell lines.

Windham TC, Parikh NU, Siwak DR, Summy JM, McConkey DJ, Kraker AJ, Gallick GE.

Oncogene. 2002 Nov 7;21(51):7797-807.

18.

PC phosphorylation increases the ability of AFAP-110 to cross-link actin filaments.

Qian Y, Baisden JM, Cherezova L, Summy JM, Guappone-Koay A, Shi X, Mast T, Pustula J, Zot HG, Mazloum N, Lee MY, Flynn DC.

Mol Biol Cell. 2002 Jul;13(7):2311-22.

19.
20.

Monoclonal antibodies directed against AFAP-110 recognize species-specific and conserved epitopes.

Qian Y, Guappone AC, Baisden JM, Hill MW, Summy JM, Flynn DC.

Hybridoma. 1999 Apr;18(2):167-75.

PMID:
10380016

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