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Musculoskeletal rheumatic complications of immune checkpoint inhibitor therapy: A single center experience.

Mooradian MJ, Nasrallah M, Gainor JF, Reynolds KL, Cohen JV, Lawrence DP, Miloslavsky EM, Kohler MJ, Sullivan RJ, Schoenfeld SR.

Semin Arthritis Rheum. 2018 Oct 16. pii: S0049-0172(18)30442-6. doi: 10.1016/j.semarthrit.2018.10.012. [Epub ahead of print]


Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.

Sade-Feldman M, Yizhak K, Bjorgaard SL, Ray JP, de Boer CG, Jenkins RW, Lieb DJ, Chen JH, Frederick DT, Barzily-Rokni M, Freeman SS, Reuben A, Hoover PJ, Villani AC, Ivanova E, Portell A, Lizotte PH, Aref AR, Eliane JP, Hammond MR, Vitzthum H, Blackmon SM, Li B, Gopalakrishnan V, Reddy SM, Cooper ZA, Paweletz CP, Barbie DA, Stemmer-Rachamimov A, Flaherty KT, Wargo JA, Boland GM, Sullivan RJ, Getz G, Hacohen N.

Cell. 2018 Nov 1;175(4):998-1013.e20. doi: 10.1016/j.cell.2018.10.038.


A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade.

Jerby-Arnon L, Shah P, Cuoco MS, Rodman C, Su MJ, Melms JC, Leeson R, Kanodia A, Mei S, Lin JR, Wang S, Rabasha B, Liu D, Zhang G, Margolais C, Ashenberg O, Ott PA, Buchbinder EI, Haq R, Hodi FS, Boland GM, Sullivan RJ, Frederick DT, Miao B, Moll T, Flaherty KT, Herlyn M, Jenkins RW, Thummalapalli R, Kowalczyk MS, Cañadas I, Schilling B, Cartwright ANR, Luoma AM, Malu S, Hwu P, Bernatchez C, Forget MA, Barbie DA, Shalek AK, Tirosh I, Sorger PK, Wucherpfennig K, Van Allen EM, Schadendorf D, Johnson BE, Rotem A, Rozenblatt-Rosen O, Garraway LA, Yoon CH, Izar B, Regev A.

Cell. 2018 Nov 1;175(4):984-997.e24. doi: 10.1016/j.cell.2018.09.006.


Meta-analysis of aberrant post-error slowing in substance use disorder: Implications for behavioral adaptation and self-control.

Sullivan RM, Perlman G, Moeller SJ.

Eur J Neurosci. 2018 Nov 1. doi: 10.1111/ejn.14229. [Epub ahead of print]


Clinical experience with combination BRAF/MEK inhibitors for melanoma with brain metastases: a real-life multicenter study.

Drago JZ, Lawrence D, Livingstone E, Zimmer L, Chen T, Giobbie-Hurder A, Amann VC, Mangana J, Siano M, Zippelius A, Dummer R, Goldinger SM, Sullivan RJ.

Melanoma Res. 2018 Oct 29. doi: 10.1097/CMR.0000000000000527. [Epub ahead of print]


Reply to Emergency management of immune-related hypophysitis: Collaboration between specialists is essential to achieve optimal outcomes.

Faje AT, Sullivan RJ.

Cancer. 2018 Oct 23. doi: 10.1002/cncr.31786. [Epub ahead of print] No abstract available.


Mapping cancer research across Central and Eastern Europe, the Russian Federation and Central Asia: Implications for future national cancer control planning.

Begum M, Lewison G, Jassem J, Mixich V, Cufer T, Nurgozhin T, Shabalkin P, Kutluk T, Voko Z, Radosavljevic D, Vrdoljiak E, Eniu A, Walewski J, Aggarwal A, Lawler M, Sullivan R.

Eur J Cancer. 2018 Oct 19;104:127-136. doi: 10.1016/j.ejca.2018.08.024. [Epub ahead of print]


Publisher Correction: Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma.

Auslander N, Zhang G, Lee JS, Frederick DT, Miao B, Moll T, Tian T, Wei Z, Madan S, Sullivan RJ, Boland G, Flaherty K, Herlyn M, Ruppin E.

Nat Med. 2018 Oct 17. doi: 10.1038/s41591-018-0247-8. [Epub ahead of print]


A Novel Web-Based Experiential Learning Platform for Medical Students (Learning Moment): Qualitative Study.

Sheng AY, Chu A, Biancarelli D, Drainoni ML, Sullivan R, Schneider JI.

JMIR Med Educ. 2018 Oct 17;4(2):e10657. doi: 10.2196/10657.


The value of European immigration for high-level UK research and clinical care: cross-sectional study.

Begum M, Lewison G, Lawler M, Sullivan R.

J R Soc Med. 2018 Oct 10:141076818803427. doi: 10.1177/0141076818803427. [Epub ahead of print]


The impact of Brexit on UK cancer research.

Lawler M, Begum M, Lewison G, Aggarwal A, Selby P, Sullivan R.

Lancet Oncol. 2018 Oct;19(10):1276-1278. doi: 10.1016/S1470-2045(18)30518-7. Epub 2018 Oct 1. No abstract available.


Intelligence and global health: assessing the role of open source and social media intelligence analysis in infectious disease outbreaks.

Bernard R, Bowsher G, Milner C, Boyle P, Patel P, Sullivan R.

Z Gesundh Wiss. 2018;26(5):509-514. doi: 10.1007/s10389-018-0899-3. Epub 2018 Feb 10.


Spinocerebellar ataxia: an update.

Sullivan R, Yau WY, O'Connor E, Houlden H.

J Neurol. 2018 Oct 3. doi: 10.1007/s00415-018-9076-4. [Epub ahead of print]


Developmental transitions in amygdala PKC isoforms and AMPA receptor expression associated with threat memory in infant rats.

Opendak M, Zanca RM, Anane E, Serrano PA, Sullivan RM.

Sci Rep. 2018 Oct 2;8(1):14679. doi: 10.1038/s41598-018-32762-y.


Mind the Graph: Foregone Health Gains in Lung Cancer.

Cameron L, Sullivan R, Luey B, Solomon B.

Semin Oncol. 2017 Dec 6. pii: S0093-7754(17)30163-X. doi: 10.1053/j.seminoncol.2017.11.004. [Epub ahead of print] No abstract available.


Mechanisms of Resistance to Immune Checkpoint Blockade.

Liu D, Jenkins RW, Sullivan RJ.

Am J Clin Dermatol. 2018 Sep 26. doi: 10.1007/s40257-018-0389-y. [Epub ahead of print] Review.


Vitamin D deficiency is associated with reduced hippocampal volume and disrupted structural connectivity in patients with mild cognitive impairment.

Al-Amin M, Bradford D, Sullivan RKP, Kurniawan ND, Moon Y, Han SH, Zalesky A, Burne THJ.

Hum Brain Mapp. 2018 Sep 25. doi: 10.1002/hbm.24380. [Epub ahead of print]


Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors: A Systematic Review and Meta-analysis.

Wang DY, Salem JE, Cohen JV, Chandra S, Menzer C, Ye F, Zhao S, Das S, Beckermann KE, Ha L, Rathmell WK, Ancell KK, Balko JM, Bowman C, Davis EJ, Chism DD, Horn L, Long GV, Carlino MS, Lebrun-Vignes B, Eroglu Z, Hassel JC, Menzies AM, Sosman JA, Sullivan RJ, Moslehi JJ, Johnson DB.

JAMA Oncol. 2018 Sep 13. doi: 10.1001/jamaoncol.2018.3923. [Epub ahead of print]


Financial Impact of Complex Cancer Surgery in India: A Study of Pancreatic Cancer.

Basavaiah G, Rent PD, Rent EG, Sullivan R, Towne M, Bak M, Sirohi B, Goel M, Shrikhande SV.

J Glob Oncol. 2018 Sep;(4):1-9. doi: 10.1200/JGO.17.00151.


Palliative Care Program Development in a Low- to Middle-Income Country: Delivery of Care by a Nongovernmental Organization in India.

Krishnan A, Rajagopal MR, Karim S, Sullivan R, Booth CM.

J Glob Oncol. 2018 Sep;(4):1-8. doi: 10.1200/JGO.17.00168.


Cancer Care for Refugees and Displaced Populations: Middle East Conflicts and Global Natural Disasters.

El Saghir NS, Soto Pérez de Celis E, Fares JE, Sullivan R.

Am Soc Clin Oncol Educ Book. 2018 May 23;(38):433-440. doi: 10.1200/EDBK_201365.


Atezolizumab Treatment Beyond Progression in Advanced NSCLC: Results From the Randomized, Phase III OAK Study.

Gandara DR, von Pawel J, Mazieres J, Sullivan R, Helland Å, Han JY, Ponce Aix S, Rittmeyer A, Barlesi F, Kubo T, Park K, Goldschmidt J, Gandhi M, Yun C, Yu W, Matheny C, He P, Sandler A, Ballinger M, Fehrenbacher L.

J Thorac Oncol. 2018 Sep 11. pii: S1556-0864(18)33043-0. doi: 10.1016/j.jtho.2018.08.2027. [Epub ahead of print]


UK newspaper reporting of the NHS cancer drugs fund, 2010 to 2015: a retrospective media analysis.

Lewison G, Aggarwal A, Roe P, Møller H, Chamberlain C, Sullivan R.

J R Soc Med. 2018 Oct;111(10):366-373. doi: 10.1177/0141076818796802. Epub 2018 Sep 13.


Results from phase II trial of HSP90 inhibitor, STA-9090 (ganetespib), in metastatic uveal melanoma.

Shah S, Luke JJ, Jacene HA, Chen T, Giobbie-Hurder A, Ibrahim N, Buchbinder EL, McDermott DF, Flaherty KT, Sullivan RJ, Lawrence DP, Ott PA, Hodi FS.

Melanoma Res. 2018 Dec;28(6):605-610. doi: 10.1097/CMR.0000000000000509.


Increases in plasma corin levels following experimental myocardial infarction reflect the severity of ischemic injury.

Wang D, Gladysheva IP, Sullivan RD, Fan TM, Mehta RM, Tripathi R, Sun Y, Reed GL.

PLoS One. 2018 Sep 7;13(9):e0202571. doi: 10.1371/journal.pone.0202571. eCollection 2018.


Posterior Thoracic Stab Wounds: Evaluating the Value of Commonly Used Radiologic Modalities.

Brigode WM, Masteller M, Chaudhuri R, Sullivan R, Vafa A.

Am Surg. 2018 Aug 1;84(8):1363-1367.


DNA repair in trinucleotide repeat ataxias.

Yau WY, O'Connor E, Sullivan R, Akijian L, Wood NW.

FEBS J. 2018 Oct;285(19):3669-3682. doi: 10.1111/febs.14644. Epub 2018 Sep 10. Review.


Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models.

Minzel W, Venkatachalam A, Fink A, Hung E, Brachya G, Burstain I, Shaham M, Rivlin A, Omer I, Zinger A, Elias S, Winter E, Erdman PE, Sullivan RW, Fung L, Mercurio F, Li D, Vacca J, Kaushansky N, Shlush L, Oren M, Levine R, Pikarsky E, Snir-Alkalay I, Ben-Neriah Y.

Cell. 2018 Sep 20;175(1):171-185.e25. doi: 10.1016/j.cell.2018.07.045. Epub 2018 Aug 23.


Early life trauma increases threat response of peri-weaning rats, reduction of axo-somatic synapses formed by parvalbumin cells and perineuronal net in the basolateral nucleus of amygdala.

Santiago AN, Lim KY, Opendak M, Sullivan RM, Aoki C.

J Comp Neurol. 2018 Aug 23. doi: 10.1002/cne.24522. [Epub ahead of print]


Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma.

Auslander N, Zhang G, Lee JS, Frederick DT, Miao B, Moll T, Tian T, Wei Z, Madan S, Sullivan RJ, Boland G, Flaherty K, Herlyn M, Ruppin E.

Nat Med. 2018 Oct;24(10):1545-1549. doi: 10.1038/s41591-018-0157-9. Epub 2018 Aug 20. Erratum in: Nat Med. 2018 Oct 17;:.


The contribution of Cyprus to non-communicable diseases and biomedical research from 2002 to 2013: implications for evidence-based health policy.

Pallari E, Lewison G, Pallari CT, Samoutis G, Begum M, Sullivan R.

Health Res Policy Syst. 2018 Aug 17;16(1):82. doi: 10.1186/s12961-018-0355-4.


A randomized usability assessment of simulated naloxone administration by community members.

Eggleston W, Podolak C, Sullivan RW, Pacelli L, Keenan M, Wojcik S.

Addiction. 2018 Dec;113(12):2300-2304. doi: 10.1111/add.14416. Epub 2018 Sep 11.


Developing institutions for cancer care in low-income and middle-income countries: from cancer units to comprehensive cancer centres.

Sirohi B, Chalkidou K, Pramesh CS, Anderson BO, Loeher P, El Dewachi O, Shamieh O, Shrikhande SV, Venkataramanan R, Parham G, Mwanahamuntu M, Eden T, Tsunoda A, Purushotham A, Stanway S, Rath GK, Sullivan R.

Lancet Oncol. 2018 Aug;19(8):e395-e406. doi: 10.1016/S1470-2045(18)30342-5. Review.


A roadmap for restoring trust in Big Data.

Lawler M, Morris AD, Sullivan R, Birney E, Middleton A, Makaroff L, Knoppers BM, Horgan D, Eggermont A.

Lancet Oncol. 2018 Aug;19(8):1014-1015. doi: 10.1016/S1470-2045(18)30425-X. No abstract available.


Maternal Regulation of Pups' Cortical Activity: Role of Serotonergic Signaling.

Courtiol E, Wilson DA, Shah R, Sullivan RM, Teixeira CM.

eNeuro. 2018 Jul 31;5(4). pii: ENEURO.0093-18.2018. doi: 10.1523/ENEURO.0093-18.2018. eCollection 2018 Jul-Aug.


Reply: Immunosuppression Does Not Reduce Antitumor Efficacy.

Mahmood SS, Sullivan RJ, Reynolds KL, Neilan TG.

J Am Coll Cardiol. 2018 Aug 7;72(6):702. doi: 10.1016/j.jacc.2018.06.005. No abstract available.


Increased transport of acetyl-CoA into the endoplasmic reticulum causes a progeria-like phenotype.

Peng Y, Shapiro SL, Banduseela VC, Dieterich IA, Hewitt KJ, Bresnick EH, Kong G, Zhang J, Schueler KL, Keller MP, Attie AD, Hacker TA, Sullivan R, Kielar-Grevstad E, Arriola Apelo SI, Lamming DW, Anderson RM, Puglielli L.

Aging Cell. 2018 Oct;17(5):e12820. doi: 10.1111/acel.12820. Epub 2018 Jul 27.


The role of targeted therapy for melanoma in the immunotherapy era.

Sullivan RJ.

Semin Cutan Med Surg. 2018 Jun;37(2):112-119. doi: 10.12788/j.sder.2018.021.


Mapping the European cancer research landscape: An evidence base for national and Pan-European research and funding.

Begum M, Lewison G, Lawler M, Sullivan R.

Eur J Cancer. 2018 Sep;100:75-84. doi: 10.1016/j.ejca.2018.04.017. Epub 2018 Jul 4.


Small and light arms violence reduction as a public health measure: the case of Libya.

Bowsher G, Bogue P, Patel P, Boyle P, Sullivan R.

Confl Health. 2018 Jul 9;12:29. doi: 10.1186/s13031-018-0162-0. eCollection 2018. Review.


Perspectives in immunotherapy: meeting report from the Immunotherapy Bridge (29-30 November, 2017, Naples, Italy).

Ascierto PA, Brugarolas J, Buonaguro L, Butterfield LH, Carbone D, Daniele B, Ferris R, Fox BA, Galon J, Gridelli C, Kaufman HL, Klebanoff CA, Melero I, Nathan P, Paulos CM, Ruella M, Sullivan R, Zarour H, Puzanov I.

J Immunother Cancer. 2018 Jul 11;6(1):69. doi: 10.1186/s40425-018-0377-z. Review.


Ipilimumab plus nivolumab and DNA-repair defects in AR-V7-expressing metastatic prostate cancer.

Boudadi K, Suzman DL, Anagnostou V, Fu W, Luber B, Wang H, Niknafs N, White JR, Silberstein JL, Sullivan R, Dowling D, Harb R, Nirschl TR, Veeneman BA, Tomlins SA, Wang Y, Jendrisak A, Graf RP, Dittamore R, Carducci MA, Eisenberger MA, Haffner MC, Meeker AK, Eshleman JR, Luo J, Velculescu VE, Drake CG, Antonarakis ES.

Oncotarget. 2018 Jun 19;9(47):28561-28571. doi: 10.18632/oncotarget.25564. eCollection 2018 Jun 19.


Forestalling BRAF-Inhibitor Resistance in a Shocking Way.

Sullivan RJ.

Clin Cancer Res. 2018 Jul 6. doi: 10.1158/1078-0432.CCR-18-1344. [Epub ahead of print]


Radiation Therapy Research: A Global Analysis 2001-2015.

Aggarwal A, Lewison G, Rodin D, Zietman A, Sullivan R, Lievens Y.

Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):767-778. doi: 10.1016/j.ijrobp.2018.03.009. Epub 2018 Mar 20. Review.


High-dose glucocorticoids for the treatment of ipilimumab-induced hypophysitis is associated with reduced survival in patients with melanoma.

Faje AT, Lawrence D, Flaherty K, Freedman C, Fadden R, Rubin K, Cohen J, Sullivan RJ.

Cancer. 2018 Sep 15;124(18):3706-3714. doi: 10.1002/cncr.31629. Epub 2018 Jul 5.


Medical oncology workload in Canada: infrastructure, supports, and delivery of clinical care.

Fundytus A, Hopman WM, Hammad N, Biagi JJ, Sullivan R, Vanderpuye V, Seruga B, Lopes G, Sengar M, Brundage MD, Booth CM.

Curr Oncol. 2018 Jun;25(3):206-212. doi: 10.3747/co.25.3999. Epub 2018 Jun 28.


A novel fibroblast activation inhibitor attenuates left ventricular remodeling and preserves cardiac function in heart failure.

Bradley JM, Spaletra P, Li Z, Sharp TE 3rd, Goodchild TT, Corral LG, Fung L, Chan KWH, Sullivan RW, Swindlehurst CA, Lefer DJ.

Am J Physiol Heart Circ Physiol. 2018 Sep 1;315(3):H563-H570. doi: 10.1152/ajpheart.00603.2017. Epub 2018 Jun 27.


Inappropriate sinus tachycardia.

Olshansky B, Sullivan RM.

Europace. 2018 Jun 19. doi: 10.1093/europace/euy128. [Epub ahead of print]


New mouse model of pulmonary hypertension induced by respiratory syncytial virus bronchiolitis.

Kimura D, Saravia J, Jaligama S, McNamara I, Vu LD, Sullivan RD, Mancarella S, You D, Cormier SA.

Am J Physiol Heart Circ Physiol. 2018 Sep 1;315(3):H581-H589. doi: 10.1152/ajpheart.00627.2017. Epub 2018 Jun 15.


Emerging investigator series: determination of biphasic core-shell droplet properties using aerosol optical tweezers.

Gorkowski K, Donahue NM, Sullivan RC.

Environ Sci Process Impacts. 2018 Jun 13. doi: 10.1039/c8em00166a. [Epub ahead of print]


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