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Gedunin- and Khivorin-Derivatives are Small Molecule Partial Agonists for Adhesion G protein Coupled Receptors GPR56 / ADGRG1 and GPR114 / ADGRG5.

Stoveken HM, Larsen SD, Smrcka AV, Tall GG.

Mol Pharmacol. 2018 Feb 23. pii: mol.117.111476. doi: 10.1124/mol.117.111476. [Epub ahead of print]


Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains.

Salzman GS, Ackerman SD, Ding C, Koide A, Leon K, Luo R, Stoveken HM, Fernandez CG, Tall GG, Piao X, Monk KR, Koide S, AraƧ D.

Neuron. 2016 Sep 21;91(6):1292-1304. doi: 10.1016/j.neuron.2016.08.022.


Dihydromunduletone Is a Small-Molecule Selective Adhesion G Protein-Coupled Receptor Antagonist.

Stoveken HM, Bahr LL, Anders MW, Wojtovich AP, Smrcka AV, Tall GG.

Mol Pharmacol. 2016 Sep;90(3):214-24. doi: 10.1124/mol.116.104828. Epub 2016 Jun 23.


Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist.

Stoveken HM, Hajduczok AG, Xu L, Tall GG.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):6194-9. doi: 10.1073/pnas.1421785112. Epub 2015 Apr 27. Erratum in: Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):E3452.

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