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Items: 28

1.

Stabilized sulforaphane for clinical use: Phytochemical delivery efficiency.

Fahey JW, Wade KL, Wehage SL, Holtzclaw WD, Liu H, Talalay P, Fuchs E, Stephenson KK.

Mol Nutr Food Res. 2017 Apr;61(4). doi: 10.1002/mnfr.201600766. Epub 2017 Feb 8.

PMID:
27935214
2.

Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase.

Fahey JW, Holtzclaw WD, Wehage SL, Wade KL, Stephenson KK, Talalay P.

PLoS One. 2015 Nov 2;10(11):e0140963. doi: 10.1371/journal.pone.0140963. eCollection 2015.

3.

Dietary amelioration of Helicobacter infection.

Fahey JW, Stephenson KK, Wallace AJ.

Nutr Res. 2015 Jun;35(6):461-73. doi: 10.1016/j.nutres.2015.03.001. Epub 2015 Mar 6. Review.

4.

Structure-activity analysis of flavonoids: direct and indirect antioxidant, and antiinflammatory potencies and toxicities.

Tsuji PA, Stephenson KK, Wade KL, Liu H, Fahey JW.

Nutr Cancer. 2013;65(7):1014-25. doi: 10.1080/01635581.2013.809127. Epub 2013 Oct 2.

PMID:
24087992
5.

Urease from Helicobacter pylori is inactivated by sulforaphane and other isothiocyanates.

Fahey JW, Stephenson KK, Wade KL, Talalay P.

Biochem Biophys Res Commun. 2013 May 24;435(1):1-7. doi: 10.1016/j.bbrc.2013.03.126. Epub 2013 Apr 11.

6.

Electrophilic tuning of the chemoprotective natural product sulforaphane.

Ahn YH, Hwang Y, Liu H, Wang XJ, Zhang Y, Stephenson KK, Boronina TN, Cole RN, Dinkova-Kostova AT, Talalay P, Cole PA.

Proc Natl Acad Sci U S A. 2010 May 25;107(21):9590-5. doi: 10.1073/pnas.1004104107. Epub 2010 May 3.

7.

Cultivar effect on Moringa oleifera glucosinolate content and taste: a pilot study.

Doerr B, Wade KL, Stephenson KK, Reed SB, Fahey JW.

Ecol Food Nutr. 2009 May-Jun;48(3):199-211. doi: 10.1080/03670240902794630.

PMID:
21883061
8.

Induction of chemoprotective phase 2 enzymes by ginseng and its components.

Lee LS, Stephenson KK, Fahey JW, Parsons TL, Lietman PS, Andrade AS, Lei X, Yun H, Soon GH, Shen P, Danishefsky S, Flexner C.

Planta Med. 2009 Aug;75(10):1129-33. doi: 10.1055/s-0029-1185508. Epub 2009 Mar 26.

PMID:
19326326
9.

A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin.

Liby K, Yore MM, Roebuck BD, Baumgartner KJ, Honda T, Sundararajan C, Yoshizawa H, Gribble GW, Williams CR, Risingsong R, Royce DB, Dinkova-Kostova AT, Stephenson KK, Egner PA, Yates MS, Groopman JD, Kensler TW, Sporn MB.

Cancer Res. 2008 Aug 15;68(16):6727-33. doi: 10.1158/0008-5472.CAN-08-1123.

10.

A dicyanotriterpenoid induces cytoprotective enzymes and reduces multiplicity of skin tumors in UV-irradiated mice.

Dinkova-Kostova AT, Jenkins SN, Wehage SL, Huso DL, Benedict AL, Stephenson KK, Fahey JW, Liu H, Liby KT, Honda T, Gribble GW, Sporn MB, Talalay P.

Biochem Biophys Res Commun. 2008 Mar 21;367(4):859-65. doi: 10.1016/j.bbrc.2008.01.026. Epub 2008 Jan 17.

PMID:
18206646
11.

Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities.

Liby K, Honda T, Williams CR, Risingsong R, Royce DB, Suh N, Dinkova-Kostova AT, Stephenson KK, Talalay P, Sundararajan C, Gribble GW, Sporn MB.

Mol Cancer Ther. 2007 Jul;6(7):2113-9.

12.

Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: a clinical phase I study.

Shapiro TA, Fahey JW, Dinkova-Kostova AT, Holtzclaw WD, Stephenson KK, Wade KL, Ye L, Talalay P.

Nutr Cancer. 2006;55(1):53-62.

PMID:
16965241
13.

Evaluation of isothiocyanates as potent inducers of carcinogen-detoxifying enzymes in the urinary bladder: critical nature of in vivo bioassay.

Munday R, Zhang Y, Fahey JW, Jobson HE, Munday CM, Li J, Stephenson KK.

Nutr Cancer. 2006;54(2):223-31.

PMID:
16898867
14.

Potent activation of mitochondria-mediated apoptosis and arrest in S and M phases of cancer cells by a broccoli sprout extract.

Tang L, Zhang Y, Jobson HE, Li J, Stephenson KK, Wade KL, Fahey JW.

Mol Cancer Ther. 2006 Apr;5(4):935-44.

15.

Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China.

Kensler TW, Chen JG, Egner PA, Fahey JW, Jacobson LP, Stephenson KK, Ye L, Coady JL, Wang JB, Wu Y, Sun Y, Zhang QN, Zhang BC, Zhu YR, Qian GS, Carmella SG, Hecht SS, Benning L, Gange SJ, Groopman JD, Talalay P.

Cancer Epidemiol Biomarkers Prev. 2005 Nov;14(11 Pt 1):2605-13.

16.

Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts.

Dinkova-Kostova AT, Jenkins SN, Fahey JW, Ye L, Wehage SL, Liby KT, Stephenson KK, Wade KL, Talalay P.

Cancer Lett. 2006 Aug 28;240(2):243-52. Epub 2005 Nov 3.

PMID:
16271437
17.

Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes.

Fahey JW, Stephenson KK, Dinkova-Kostova AT, Egner PA, Kensler TW, Talalay P.

Carcinogenesis. 2005 Jul;26(7):1247-55. Epub 2005 Mar 17.

PMID:
15774490
18.

Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress.

Dinkova-Kostova AT, Liby KT, Stephenson KK, Holtzclaw WD, Gao X, Suh N, Williams C, Risingsong R, Honda T, Gribble GW, Sporn MB, Talalay P.

Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4584-9. Epub 2005 Mar 14.

19.

The "Prochaska" microtiter plate bioassay for inducers of NQO1.

Fahey JW, Dinkova-Kostova AT, Stephenson KK, Talalay P.

Methods Enzymol. 2004;382:243-58. Review. No abstract available.

PMID:
15047106
20.

The p16 (CDKN2a/INK4a) tumor-suppressor gene in head and neck squamous cell carcinoma: a promoter methylation and protein expression study in 100 cases.

Ai L, Stephenson KK, Ling W, Zuo C, Mukunyadzi P, Suen JY, Hanna E, Fan CY.

Mod Pathol. 2003 Sep;16(9):944-50.

21.

Separation and purification of glucosinolates from crude plant homogenates by high-speed counter-current chromatography.

Fahey JW, Wade KL, Stephenson KK, Chou FE.

J Chromatogr A. 2003 May 9;996(1-2):85-93.

PMID:
12830910
23.
24.

Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors.

Fahey JW, Haristoy X, Dolan PM, Kensler TW, Scholtus I, Stephenson KK, Talalay P, Lozniewski A.

Proc Natl Acad Sci U S A. 2002 May 28;99(11):7610-5.

25.

Analysis of glucosinolates from broccoli and other cruciferous vegetables by hydrophilic interaction liquid chromatography.

Troyer JK, Stephenson KK, Fahey JW.

J Chromatogr A. 2001 Jun 15;919(2):299-304.

PMID:
11442035
26.
27.

Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans.

Shapiro TA, Fahey JW, Wade KL, Stephenson KK, Talalay P.

Cancer Epidemiol Biomarkers Prev. 2001 May;10(5):501-8.

28.

Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables.

Shapiro TA, Fahey JW, Wade KL, Stephenson KK, Talalay P.

Cancer Epidemiol Biomarkers Prev. 1998 Dec;7(12):1091-100.

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