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Items: 1 to 50 of 143

1.

Brucella Peptide Cross-Reactive MHC I Presentation Activates SIINFEKL-Specific TCR Expressing T Cells.

Harms JS, Khan M, Hall C, Splitter GA, Homan EJ, Bremel RD, Smith JA.

Infect Immun. 2018 May 7. pii: IAI.00281-18. doi: 10.1128/IAI.00281-18. [Epub ahead of print]

2.

The Bacterial Second Messenger Cyclic di-GMP Regulates Brucella Pathogenesis and Leads to Altered Host Immune Response.

Khan M, Harms JS, Marim FM, Armon L, Hall CL, Liu YP, Banai M, Oliveira SC, Splitter GA, Smith JA.

Infect Immun. 2016 Nov 18;84(12):3458-3470. Print 2016 Dec.

3.

CD8+ T cell exhaustion, suppressed gamma interferon production, and delayed memory response induced by chronic Brucella melitensis infection.

Durward-Diioia M, Harms J, Khan M, Hall C, Smith JA, Splitter GA.

Infect Immun. 2015 Dec;83(12):4759-71. doi: 10.1128/IAI.01184-15. Epub 2015 Sep 28.

4.

Let There Be Light! Bioluminescent Imaging to Study Bacterial Pathogenesis in Live Animals and Plants.

Kassem II, Splitter GA, Miller S, Rajashekara G.

Adv Biochem Eng Biotechnol. 2016;154:119-45. doi: 10.1007/10_2014_280.

PMID:
25395174
5.

Draft Genome Sequence of the Field Isolate Brucella melitensis Strain Bm IND1 from India.

Rao SB, Gupta VK, Kumar M, Hegde NR, Splitter GA, Reddanna P, Radhakrishnan GK.

Genome Announc. 2014 May 29;2(3). pii: e00497-14. doi: 10.1128/genomeA.00497-14.

6.

Brucella induces an unfolded protein response via TcpB that supports intracellular replication in macrophages.

Smith JA, Khan M, Magnani DD, Harms JS, Durward M, Radhakrishnan GK, Liu YP, Splitter GA.

PLoS Pathog. 2013;9(12):e1003785. doi: 10.1371/journal.ppat.1003785. Epub 2013 Dec 5.

7.

Modulation of host microtubule dynamics by pathogenic bacteria.

Radhakrishnan GK, Splitter GA.

Biomol Concepts. 2012 Dec 1;3(6):571-580.

8.

Osteoarticular tissue infection and development of skeletal pathology in murine brucellosis.

Magnani DM, Lyons ET, Forde TS, Shekhani MT, Adarichev VA, Splitter GA.

Dis Model Mech. 2013 May;6(3):811-8. doi: 10.1242/dmm.011056. Epub 2013 Mar 8.

9.

Active evasion of CTL mediated killing and low quality responding CD8+ T cells contribute to persistence of brucellosis.

Durward M, Radhakrishnan G, Harms J, Bareiss C, Magnani D, Splitter GA.

PLoS One. 2012;7(4):e34925. doi: 10.1371/journal.pone.0034925. Epub 2012 Apr 25.

10.

Modulation of microtubule dynamics by a TIR domain protein from the intracellular pathogen Brucella melitensis.

Radhakrishnan GK, Harms JS, Splitter GA.

Biochem J. 2011 Oct 1;439(1):79-83. doi: 10.1042/BJ20110577.

11.

Biochemical and functional analysis of TIR domain containing protein from Brucella melitensis.

Radhakrishnan GK, Splitter GA.

Biochem Biophys Res Commun. 2010 Jun 18;397(1):59-63. doi: 10.1016/j.bbrc.2010.05.056. Epub 2010 May 13.

12.

Discordant Brucella melitensis antigens yield cognate CD8+ T cells in vivo.

Durward MA, Harms J, Magnani DM, Eskra L, Splitter GA.

Infect Immun. 2010 Jan;78(1):168-76. doi: 10.1128/IAI.00994-09. Epub 2009 Nov 2.

13.

Nondividing but metabolically active gamma-irradiated Brucella melitensis is protective against virulent B. melitensis challenge in mice.

Magnani DM, Harms JS, Durward MA, Splitter GA.

Infect Immun. 2009 Nov;77(11):5181-9. doi: 10.1128/IAI.00231-09. Epub 2009 Aug 24.

14.

Brucella regulators: self-control in a hostile environment.

Rambow-Larsen AA, Petersen EM, Gourley CR, Splitter GA.

Trends Microbiol. 2009 Aug;17(8):371-7. doi: 10.1016/j.tim.2009.05.006. Epub 2009 Aug 5. Review.

15.

Brucella TIR Domain-containing Protein Mimics Properties of the Toll-like Receptor Adaptor Protein TIRAP.

Radhakrishnan GK, Yu Q, Harms JS, Splitter GA.

J Biol Chem. 2009 Apr 10;284(15):9892-8. doi: 10.1074/jbc.M805458200. Epub 2009 Feb 5.

16.

Evaluation of recombinant invasive, non-pathogenic Eschericia coli as a vaccine vector against the intracellular pathogen, Brucella.

Harms JS, Durward MA, Magnani DM, Splitter GA.

J Immune Based Ther Vaccines. 2009 Jan 6;7:1. doi: 10.1186/1476-8518-7-1.

17.

DNA recognition properties of the cell-to-cell movement protein (MP) of soybean isolate of Mungbean yellow mosaic India virus (MYMIV-Sb).

Radhakrishnan GK, Splitter GA, Usha R.

Virus Res. 2008 Feb;131(2):152-9. Epub 2007 Oct 18.

PMID:
17949843
18.

Blue-light-activated histidine kinases: two-component sensors in bacteria.

Swartz TE, Tseng TS, Frederickson MA, Paris G, Comerci DJ, Rajashekara G, Kim JG, Mudgett MB, Splitter GA, Ugalde RA, Goldbaum FA, Briggs WR, Bogomolni RA.

Science. 2007 Aug 24;317(5841):1090-3.

19.

DNA vaccine construct incorporating intercellular trafficking and intracellular targeting motifs effectively primes and induces memory B- and T-cell responses in outbred animals.

Mwangi W, Brown WC, Splitter GA, Davies CJ, Howard CJ, Hope JC, Aida Y, Zhuang Y, Hunter BJ, Palmer GH.

Clin Vaccine Immunol. 2007 Mar;14(3):304-11. Epub 2007 Jan 10.

20.

CGHScan: finding variable regions using high-density microarray comparative genomic hybridization data.

Anderson BD, Gilson MC, Scott AA, Biehl BS, Glasner JD, Rajashekara G, Splitter GA, Perna NT.

BMC Genomics. 2006 Apr 25;7:91.

21.

Attenuated bioluminescent Brucella melitensis mutants GR019 (virB4), GR024 (galE), and GR026 (BMEI1090-BMEI1091) confer protection in mice.

Rajashekara G, Glover DA, Banai M, O'Callaghan D, Splitter GA.

Infect Immun. 2006 May;74(5):2925-36.

22.

Temporal analysis of pathogenic events in virulent and avirulent Brucella melitensis infections.

Rajashekara G, Glover DA, Krepps M, Splitter GA.

Cell Microbiol. 2005 Oct;7(10):1459-73.

PMID:
16153245
23.
24.

Nuclear and mitochondrial localization signals overlap within bovine herpesvirus 1 tegument protein VP22.

Zhu J, Qiu Z, Wiese C, Ishii Y, Friedrichsen J, Rajashekara G, Splitter GA.

J Biol Chem. 2005 Apr 22;280(16):16038-44. Epub 2005 Feb 10.

25.

Bovine herpesvirus VP22 induces apoptosis in neuroblastoma cells by upregulating the expression ratio of Bax to Bcl-2.

Qiu Z, Zhu J, Harms JS, Friedrichsen J, Splitter GA.

Hum Gene Ther. 2005 Jan;16(1):101-8.

PMID:
15703493
27.

Denitrification genes regulate Brucella virulence in mice.

Baek SH, Rajashekara G, Splitter GA, Shapleigh JP.

J Bacteriol. 2004 Sep;186(18):6025-31.

28.

Comparison of bovine leukemia virus (BLV) and CMV promoter-driven reporter gene expression in BLV-infected and non-infected cells.

Harms JS, Eakle KA, Kuo LS, Bremel RD, Splitter GA.

Genet Vaccines Ther. 2004 Aug 24;2(1):11.

29.

Comparative whole-genome hybridization reveals genomic islands in Brucella species.

Rajashekara G, Glasner JD, Glover DA, Splitter GA.

J Bacteriol. 2004 Aug;186(15):5040-51.

31.

Role of Toll-like receptor 4 in induction of cell-mediated immunity and resistance to Brucella abortus infection in mice.

Campos MA, Rosinha GM, Almeida IC, Salgueiro XS, Jarvis BW, Splitter GA, Qureshi N, Bruna-Romero O, Gazzinelli RT, Oliveira SC.

Infect Immun. 2004 Jan;72(1):176-86.

34.

Virulence criteria for Brucella abortus strains as determined by interferon regulatory factor 1-deficient mice.

Ko J, Gendron-Fitzpatrick A, Ficht TA, Splitter GA.

Infect Immun. 2002 Dec;70(12):7004-12.

36.
37.
40.

A genetic immunization adjuvant system based on BVP22-antigen fusion.

Oliveira SC, Harms JS, Afonso RR, Splitter GA.

Hum Gene Ther. 2001 Jul 1;12(10):1353-9.

PMID:
11440628
41.

Biolistic-mediated gene transfer using the bovine herpesvirus-1 glycoprotein D is an effective delivery system to induce neutralizing antibodies in its natural host.

Oliveira SC, Harms JS, Rosinha GM, Rodarte RS, Rech EL, Splitter GA.

J Immunol Methods. 2000 Nov 1;245(1-2):109-18.

PMID:
11042288
43.
46.
47.

Mapping T and B lymphocyte epitopes of bovine herpesvirus-1 glycoprotein B.

Gao Y, Wang C, Splitter GA.

J Gen Virol. 1999 Oct;80 ( Pt 10):2699-704.

PMID:
10573163
48.
49.
50.

Regulation of transgene expression in genetic immunization.

Harms JS, Oliveira SC, Splitter GA.

Braz J Med Biol Res. 1999 Feb;32(2):155-62.

PMID:
10347750

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