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Items: 27


Antibiotic-Induced Pathobiont Dissemination Accelerates Mortality in Severe Experimental Pancreatitis.

Soares FS, Amaral FC, Silva NLC, Valente MR, Santos LKR, Yamashiro LH, Scheffer MC, Castanheira FVES, Ferreira RG, Gehrke L, Alves-Filho JC, Silva LP, Báfica A, Spiller F.

Front Immunol. 2017 Dec 22;8:1890. doi: 10.3389/fimmu.2017.01890. eCollection 2017.


Murine Red Blood Cells Lack Ligands for B Cell Siglecs, Allowing Strong Activation by Erythrocyte Surface Antigens.

Spiller F, Nycholat CM, Kikuchi C, Paulson JC, Macauley MS.

J Immunol. 2018 Feb 1;200(3):949-956. doi: 10.4049/jimmunol.1701257. Epub 2017 Dec 29.


Glucose homeostasis in two degrees of sepsis lethality induced by caecum ligation and puncture in mice.

Ferreira FBD, Dos Santos C, Bruxel MA, Nunes EA, Spiller F, Rafacho A.

Int J Exp Pathol. 2017 Dec;98(6):329-340. doi: 10.1111/iep.12255. Epub 2017 Dec 11.


Molecular basis for Cdk1-regulated timing of Mis18 complex assembly and CENP-A deposition.

Spiller F, Medina-Pritchard B, Abad MA, Wear MA, Molina O, Earnshaw WC, Jeyaprakash AA.

EMBO Rep. 2017 Jun;18(6):894-905. doi: 10.15252/embr.201643564. Epub 2017 Apr 4.


Centromere localization and function of Mis18 requires Yippee-like domain-mediated oligomerization.

Subramanian L, Medina-Pritchard B, Barton R, Spiller F, Kulasegaran-Shylini R, Radaviciute G, Allshire RC, Arockia Jeyaprakash A.

EMBO Rep. 2016 Apr;17(4):496-507. doi: 10.15252/embr.201541520. Epub 2016 Feb 26.


MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response.

Sônego F, Castanheira FV, Czaikoski PG, Kanashiro A, Souto FO, França RO, Nascimento DC, Freitas A, Spiller F, Cunha LD, Zamboni DS, Alves-Filho JC, Cunha FQ.

PLoS One. 2014 Aug 1;9(8):e103734. doi: 10.1371/journal.pone.0103734. eCollection 2014.


Decreased levels of alpha-1-acid glycoprotein are related to the mortality of septic patients in the emergency department.

Barroso-Sousa R, Lobo RR, Mendonça PR, Memória RR, Spiller F, Cunha FQ, Pazin-Filho A.

Clinics (Sao Paulo). 2013;68(8):1134-9. doi: 10.6061/clinics/2013(08)12.


Possible mechanisms of neutrophil activation in Behçet's disease.

Neves FS, Spiller F.

Int Immunopharmacol. 2013 Dec;17(4):1206-10. doi: 10.1016/j.intimp.2013.07.017. Epub 2013 Aug 23. Review.


WITHDRAWN: Neutrophil activation in Behçet's Disease.

Neves FS, Spiller F.

Int Immunopharmacol. 2013 Aug 11. pii: S1567-5769(13)00291-9. doi: 10.1016/j.intimp.2013.07.006. [Epub ahead of print]


Histamine h2 receptor signaling in the pathogenesis of sepsis: studies in a murine diabetes model.

Carlos D, Spiller F, Souto FO, Trevelin SC, Borges VF, de Freitas A, Alves-Filho JC, Silva JS, Ryffel B, Cunha FQ.

J Immunol. 2013 Aug 1;191(3):1373-82. doi: 10.4049/jimmunol.1202907. Epub 2013 Jul 1.


Heme oxygenase inhibition enhances neutrophil migration into the bronchoalveolar spaces and improves the outcome of murine pneumonia-induced sepsis.

Czaikoski PG, Nascimento DC, Sônego F, de Freitas A, Turato WM, de Carvalho MA, Santos RS, de Oliveira GP, dos Santos Samary C, Tefe-Silva C, Alves-Filho JC, Ferreira SH, Rossi MA, Rocco PR, Spiller F, Cunha FQ.

Shock. 2013 Apr;39(4):389-96. doi: 10.1097/SHK.0b013e31828bbcf9.


α1-Acid glycoprotein decreases neutrophil migration and increases susceptibility to sepsis in diabetic mice.

Spiller F, Carlos D, Souto FO, de Freitas A, Soares FS, Vieira SM, Paula FJ, Alves-Filho JC, Cunha FQ.

Diabetes. 2012 Jun;61(6):1584-91. doi: 10.2337/db11-0825. Epub 2012 Mar 13.


Sildenafil improves the beneficial hemodynamic effects exerted by atorvastatin during acute pulmonary thromboembolism.

Neto-Neves EM, Dias-Junior CA, Uzuelli JA, Pereira RP, Spiller F, Czaikoski PG, Tanus-Santos JE.

Eur J Pharmacol. 2011 Nov 30;670(2-3):554-60. doi: 10.1016/j.ejphar.2011.09.018. Epub 2011 Sep 21.


Divergent role of heme oxygenase inhibition in the pathogenesis of sepsis.

Freitas A, Alves-Filho JC, Trevelin SC, Spiller F, Suavinha MM, Nascimento DC, Pestana CR, Dal-Secco D, Sônego F, Czaikoski PG, Curti C, Barja-Fidalgo C, Cunha FQ.

Shock. 2011 Jun;35(6):550-9. doi: 10.1097/SHK.0b013e31820e1ef0.


Inhibition of neutrophil migration by hemopexin leads to increased mortality due to sepsis in mice.

Spiller F, Costa C, Souto FO, Vinchi F, Mestriner FL, Laure HJ, Alves-Filho JC, Freitas A, Rosa JC, Ferreira SH, Altruda F, Hirsch E, Greene LJ, Tolosano E, Cunha FQ.

Am J Respir Crit Care Med. 2011 Apr 1;183(7):922-31. doi: 10.1164/rccm.201002-0223OC. Epub 2010 Oct 22.


Inhibition of guanylyl cyclase restores neutrophil migration and maintains bactericidal activity increasing survival in sepsis.

Paula-Neto HA, Alves-Filho JC, Souto FO, Spiller F, Amêndola RS, Freitas A, Cunha FQ, Barja-Fidalgo C.

Shock. 2011 Jan;35(1):17-27. doi: 10.1097/SHK.0b013e3181e37ea8.


Neutrophil paralysis in sepsis.

Alves-Filho JC, Spiller F, Cunha FQ.

Shock. 2010 Sep;34 Suppl 1:15-21. doi: 10.1097/SHK.0b013e3181e7e61b. Review.


Chronic treatment with quercetin does not inhibit angiotensin-converting enzyme in vivo or in vitro.

Neto-Neves EM, Montenegro MF, Dias-Junior CA, Spiller F, Kanashiro A, Tanus-Santos JE.

Basic Clin Pharmacol Toxicol. 2010 Oct;107(4):825-9. doi: 10.1111/j.1742-7843.2010.00583.x.


Hydrogen sulfide improves neutrophil migration and survival in sepsis via K+ATP channel activation.

Spiller F, Orrico MI, Nascimento DC, Czaikoski PG, Souto FO, Alves-Filho JC, Freitas A, Carlos D, Montenegro MF, Neto AF, Ferreira SH, Rossi MA, Hothersall JS, Assreuy J, Cunha FQ.

Am J Respir Crit Care Med. 2010 Aug 1;182(3):360-8. doi: 10.1164/rccm.200907-1145OC. Epub 2010 Mar 25.


Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis.

Alves-Filho JC, Freitas A, Souto FO, Spiller F, Paula-Neto H, Silva JS, Gazzinelli RT, Teixeira MM, Ferreira SH, Cunha FQ.

Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):4018-23. doi: 10.1073/pnas.0900196106. Epub 2009 Feb 20.


The role of neutrophils in severe sepsis.

Alves-Filho JC, de Freitas A, Spiller F, Souto FO, Cunha FQ.

Shock. 2008 Oct;30 Suppl 1:3-9. doi: 10.1097/SHK.0b013e3181818466. Review.


Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation.

Spiller F, Alves MK, Vieira SM, Carvalho TA, Leite CE, Lunardelli A, Poloni JA, Cunha FQ, de Oliveira JR.

J Pharm Pharmacol. 2008 Apr;60(4):473-8. doi: 10.1211/jpp.60.4.0010.


Acute-phase protein alpha-1-acid glycoprotein mediates neutrophil migration failure in sepsis by a nitric oxide-dependent mechanism.

Mestriner FL, Spiller F, Laure HJ, Souto FO, Tavares-Murta BM, Rosa JC, Basile-Filho A, Ferreira SH, Greene LJ, Cunha FQ.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19595-600. Epub 2007 Nov 28.


Peroxynitrite mediates the failure of neutrophil migration in severe polymicrobial sepsis in mice.

Torres-Dueñas D, Celes MR, Freitas A, Alves-Filho JC, Spiller F, Dal-Secco D, Dalto VF, Rossi MA, Ferreira SH, Cunha FQ.

Br J Pharmacol. 2007 Oct;152(3):341-52. Epub 2007 Jul 16.


Down-regulation of CXCR2 on neutrophils in severe sepsis is mediated by inducible nitric oxide synthase-derived nitric oxide.

Rios-Santos F, Alves-Filho JC, Souto FO, Spiller F, Freitas A, Lotufo CM, Soares MB, Dos Santos RR, Teixeira MM, Cunha FQ.

Am J Respir Crit Care Med. 2007 Mar 1;175(5):490-7. Epub 2006 Nov 30.


Increased resistance of glioma cell lines to extracellular ATP cytotoxicity.

Morrone FB, Horn AP, Stella J, Spiller F, Sarkis JJ, Salbego CG, Lenz G, Battastini AM.

J Neurooncol. 2005 Jan;71(2):135-40.


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