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Items: 31

1.

Long-Duration Complete Remissions of Diffuse Large B Cell Lymphoma after Anti-CD19 Chimeric Antigen Receptor T Cell Therapy.

Kochenderfer JN, Somerville RPT, Lu T, Yang JC, Sherry RM, Feldman SA, McIntyre L, Bot A, Rossi J, Lam N, Rosenberg SA.

Mol Ther. 2017 Oct 4;25(10):2245-2253. doi: 10.1016/j.ymthe.2017.07.004. Epub 2017 Jul 13.

PMID:
28803861
2.

Treatment of metastatic uveal melanoma with adoptive transfer of tumour-infiltrating lymphocytes: a single-centre, two-stage, single-arm, phase 2 study.

Chandran SS, Somerville RPT, Yang JC, Sherry RM, Klebanoff CA, Goff SL, Wunderlich JR, Danforth DN, Zlott D, Paria BC, Sabesan AC, Srivastava AK, Xi L, Pham TH, Raffeld M, White DE, Toomey MA, Rosenberg SA, Kammula US.

Lancet Oncol. 2017 Jun;18(6):792-802. doi: 10.1016/S1470-2045(17)30251-6. Epub 2017 Apr 7.

PMID:
28395880
3.

Characterization of an Immunogenic Mutation in a Patient with Metastatic Triple-Negative Breast Cancer.

Assadipour Y, Zacharakis N, Crystal JS, Prickett TD, Gartner JJ, Somerville RPT, Xu H, Black MA, Jia L, Chinnasamy H, Kriley I, Lu L, Wunderlich JR, Zheng Z, Lu YC, Robbins PF, Rosenberg SA, Goff SL, Feldman SA.

Clin Cancer Res. 2017 Aug 1;23(15):4347-4353. doi: 10.1158/1078-0432.CCR-16-1423. Epub 2017 Apr 4.

PMID:
28377481
4.

Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels.

Kochenderfer JN, Somerville RPT, Lu T, Shi V, Bot A, Rossi J, Xue A, Goff SL, Yang JC, Sherry RM, Klebanoff CA, Kammula US, Sherman M, Perez A, Yuan CM, Feldman T, Friedberg JW, Roschewski MJ, Feldman SA, McIntyre L, Toomey MA, Rosenberg SA.

J Clin Oncol. 2017 Jun 1;35(16):1803-1813. doi: 10.1200/JCO.2016.71.3024. Epub 2017 Mar 14.

PMID:
28291388
5.

Genetic and biochemical evidence that gastrulation defects in Pofut2 mutants result from defects in ADAMTS9 secretion.

Benz BA, Nandadasa S, Takeuchi M, Grady RC, Takeuchi H, LoPilato RK, Kakuda S, Somerville RPT, Apte SS, Haltiwanger RS, Holdener BC.

Dev Biol. 2016 Aug 1;416(1):111-122. doi: 10.1016/j.ydbio.2016.05.038. Epub 2016 Jun 10.

6.

Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.

Goff SL, Dudley ME, Citrin DE, Somerville RP, Wunderlich JR, Danforth DN, Zlott DA, Yang JC, Sherry RM, Kammula US, Klebanoff CA, Hughes MS, Restifo NP, Langhan MM, Shelton TE, Lu L, Kwong ML, Ilyas S, Klemen ND, Payabyab EC, Morton KE, Toomey MA, Steinberg SM, White DE, Rosenberg SA.

J Clin Oncol. 2016 Jul 10;34(20):2389-97. doi: 10.1200/JCO.2016.66.7220. Epub 2016 May 23.

7.

Allogeneic T Cells That Express an Anti-CD19 Chimeric Antigen Receptor Induce Remissions of B-Cell Malignancies That Progress After Allogeneic Hematopoietic Stem-Cell Transplantation Without Causing Graft-Versus-Host Disease.

Brudno JN, Somerville RP, Shi V, Rose JJ, Halverson DC, Fowler DH, Gea-Banacloche JC, Pavletic SZ, Hickstein DD, Lu TL, Feldman SA, Iwamoto AT, Kurlander R, Maric I, Goy A, Hansen BG, Wilder JS, Blacklock-Schuver B, Hakim FT, Rosenberg SA, Gress RE, Kochenderfer JN.

J Clin Oncol. 2016 Apr 1;34(10):1112-21. doi: 10.1200/JCO.2015.64.5929. Epub 2016 Jan 25.

8.

Immunogenicity of somatic mutations in human gastrointestinal cancers.

Tran E, Ahmadzadeh M, Lu YC, Gros A, Turcotte S, Robbins PF, Gartner JJ, Zheng Z, Li YF, Ray S, Wunderlich JR, Somerville RP, Rosenberg SA.

Science. 2015 Dec 11;350(6266):1387-90. doi: 10.1126/science.aad1253. Epub 2015 Oct 29.

9.

Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor.

Kochenderfer JN, Dudley ME, Kassim SH, Somerville RP, Carpenter RO, Stetler-Stevenson M, Yang JC, Phan GQ, Hughes MS, Sherry RM, Raffeld M, Feldman S, Lu L, Li YF, Ngo LT, Goy A, Feldman T, Spaner DE, Wang ML, Chen CC, Kranick SM, Nath A, Nathan DA, Morton KE, Toomey MA, Rosenberg SA.

J Clin Oncol. 2015 Feb 20;33(6):540-9. doi: 10.1200/JCO.2014.56.2025. Epub 2014 Aug 25.

10.

Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer.

Tran E, Turcotte S, Gros A, Robbins PF, Lu YC, Dudley ME, Wunderlich JR, Somerville RP, Hogan K, Hinrichs CS, Parkhurst MR, Yang JC, Rosenberg SA.

Science. 2014 May 9;344(6184):641-5. doi: 10.1126/science.1251102.

11.

From lipoproteins to chondrocytes: a brief summary of the European Medicines Agency's regulatory guidelines for advanced therapy medicinal products.

Kassim SH, Somerville RP.

Hum Gene Ther. 2013 Jun;24(6):568-70. doi: 10.1089/hum.2013.101. No abstract available.

12.

Randomized selection design trial evaluating CD8+-enriched versus unselected tumor-infiltrating lymphocytes for adoptive cell therapy for patients with melanoma.

Dudley ME, Gross CA, Somerville RP, Hong Y, Schaub NP, Rosati SF, White DE, Nathan D, Restifo NP, Steinberg SM, Wunderlich JR, Kammula US, Sherry RM, Yang JC, Phan GQ, Hughes MS, Laurencot CM, Rosenberg SA.

J Clin Oncol. 2013 Jun 10;31(17):2152-9. doi: 10.1200/JCO.2012.46.6441. Epub 2013 May 6.

13.

Bioreactors get personal.

Somerville RP, Dudley ME.

Oncoimmunology. 2012 Nov 1;1(8):1435-1437.

14.

Clinical scale rapid expansion of lymphocytes for adoptive cell transfer therapy in the WAVE® bioreactor.

Somerville RP, Devillier L, Parkhurst MR, Rosenberg SA, Dudley ME.

J Transl Med. 2012 Apr 4;10:69. doi: 10.1186/1479-5876-10-69.

15.

Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation.

Enomoto H, Nelson CM, Somerville RP, Mielke K, Dixon LJ, Powell K, Apte SS.

Development. 2010 Dec;137(23):4029-38. doi: 10.1242/dev.050591. Epub 2010 Nov 1.

16.

ADAMTS9 is a cell-autonomously acting, anti-angiogenic metalloprotease expressed by microvascular endothelial cells.

Koo BH, Coe DM, Dixon LJ, Somerville RP, Nelson CM, Wang LW, Young ME, Lindner DJ, Apte SS.

Am J Pathol. 2010 Mar;176(3):1494-504. doi: 10.2353/ajpath.2010.090655. Epub 2010 Jan 21.

17.

Regulation of ADAMTS9 secretion and enzymatic activity by its propeptide.

Koo BH, Longpré JM, Somerville RP, Alexander JP, Leduc R, Apte SS.

J Biol Chem. 2007 Jun 1;282(22):16146-54. Epub 2007 Apr 2.

18.

O-fucosylation of thrombospondin type 1 repeats in ADAMTS-like-1/punctin-1 regulates secretion: implications for the ADAMTS superfamily.

Wang LW, Dlugosz M, Somerville RP, Raed M, Haltiwanger RS, Apte SS.

J Biol Chem. 2007 Jun 8;282(23):17024-31. Epub 2007 Mar 29.

19.
20.

Cell-surface processing of pro-ADAMTS9 by furin.

Koo BH, Longpré JM, Somerville RP, Alexander JP, Leduc R, Apte SS.

J Biol Chem. 2006 May 5;281(18):12485-94. Epub 2006 Mar 14.

21.

Adamts9 is widely expressed during mouse embryo development.

Jungers KA, Le Goff C, Somerville RP, Apte SS.

Gene Expr Patterns. 2005 Jun;5(5):609-17. Epub 2005 Apr 20.

PMID:
15939373
22.

Discovery and characterization of a novel, widely expressed metalloprotease, ADAMTS10, and its proteolytic activation.

Somerville RP, Jungers KA, Apte SS.

J Biol Chem. 2004 Dec 3;279(49):51208-17. Epub 2004 Sep 7.

23.

ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a mucin domain.

Somerville RP, Longpré JM, Apel ED, Lewis RM, Wang LW, Sanes JR, Leduc R, Apte SS.

J Biol Chem. 2004 Aug 20;279(34):35159-75. Epub 2004 Jun 10.

24.

Matrix metalloproteinases: old dogs with new tricks.

Somerville RP, Oblander SA, Apte SS.

Genome Biol. 2003;4(6):216. Epub 2003 May 29. Review.

25.

Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.

Somerville RP, Longpre JM, Jungers KA, Engle JM, Ross M, Evanko S, Wight TN, Leduc R, Apte SS.

J Biol Chem. 2003 Mar 14;278(11):9503-13. Epub 2003 Jan 3.

26.

Identification of the promoter, genomic structure, and mouse ortholog of LGI1.

Somerville RP, Chernova O, Liu S, Shoshan Y, Cowell JK.

Mamm Genome. 2000 Aug;11(8):622-7.

PMID:
10920229
27.

Radiation-induced meningioma: a distinct molecular genetic pattern?

Shoshan Y, Chernova O, Juen SS, Somerville RP, Israel Z, Barnett GH, Cowell JK.

J Neuropathol Exp Neurol. 2000 Jul;59(7):614-20.

PMID:
10901233
28.

A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors.

Chernova OB, Somerville RP, Cowell JK.

Oncogene. 1998 Dec 3;17(22):2873-81.

29.
30.

Phenotypic and genotypic alterations associated with the attenuation of a Theileria annulata vaccine cell line from Turkey.

Somerville RP, Littlebury P, Pipano E, Brown CG, Shkap V, Adamson RE, Oliver RA, Glass EJ, Hall FR.

Vaccine. 1998 Apr;16(6):569-75.

PMID:
9569467
31.

Metastasis of Theileria annulata macroschizont-infected cells in scid mice is mediated by matrix metalloproteinases.

Somerville RP, Adamson RE, Brown CG, Hall FR.

Parasitology. 1998 Mar;116 ( Pt 3):223-8.

PMID:
9550215

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