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Forming next-generation antibody-nanoparticle conjugates through the oriented installation of non-engineered antibody fragments.

Greene MK, Richards DA, Nogueira JCF, Campbell K, Smyth P, Fernández M, Scott CJ, Chudasama V.

Chem Sci. 2017 Aug 14;9(1):79-87. doi: 10.1039/c7sc02747h. eCollection 2018 Jan 7.


The Experience of Persons With Multiple Sclerosis Using MS INFoRm: An Interactive Fatigue Management Resource.

Pétrin J, Akbar N, Turpin K, Smyth P, Finlayson M.

Qual Health Res. 2018 Apr;28(5):778-788. doi: 10.1177/1049732317753584. Epub 2018 Feb 7.


Penumbral Imaging-Based Thrombolysis with Tenecteplase Is Feasible up to 24 Hours after Symptom Onset.

Kate M, Wannamaker R, Kamble H, Riaz P, Gioia LC, Buck B, Jeerakathil T, Smyth P, Shuaib A, Butcher K, Emery D.

J Stroke. 2018 Jan;20(1):122-130. doi: 10.5853/jos.2017.00178. Epub 2018 Jan 31.


A pilot mixed-methods evaluation of MS INFoRm: a self-directed fatigue management resource for individuals with multiple sclerosis.

Akbar N, Turpin K, Petrin J, Smyth P, Finlayson M.

Int J Rehabil Res. 2018 Jan 10. doi: 10.1097/MRR.0000000000000271. [Epub ahead of print]


A novel role for the macrophage galactose-type lectin receptor in mediating von Willebrand factor clearance.

Ward SE, O'Sullivan JM, Drakeford C, Aguila S, Jondle CN, Sharma J, Fallon PG, Brophy TM, Preston RJS, Smyth P, Sheils O, Chion A, O'Donnell JS.

Blood. 2018 Feb 22;131(8):911-916. doi: 10.1182/blood-2017-06-787853. Epub 2017 Dec 27.


Evaluation of NGS and RT-PCR Methods for ALK Rearrangement in European NSCLC Patients: Results from the European Thoracic Oncology Platform Lungscape Project.

Letovanec I, Finn S, Zygoura P, Smyth P, Soltermann A, Bubendorf L, Speel EJ, Marchetti A, Nonaka D, Monkhorst K, Hager H, Martorell M, Sejda A, Cheney R, Hernandez-Losa J, Verbeken E, Weder W, Savic S, Di Lorito A, Navarro A, Felip E, Warth A, Baas P, Meldgaard P, Blackhall F, Dingemans AM, Dienemann H, Dziadziuszko R, Vansteenkiste J, O'Brien C, Geiger T, Sherlock J, Schageman J, Dafni U, Kammler R, Kerr K, Thunnissen E, Stahel R, Peters S; European Thoracic Oncology Platform Lungscape Consortium.

J Thorac Oncol. 2018 Mar;13(3):413-425. doi: 10.1016/j.jtho.2017.11.117. Epub 2017 Nov 27.


miR-223 potentially targets SWI/SNF complex protein SMARCD1 in atypical proliferative serous tumor and high-grade ovarian serous carcinoma.

Arts FA, Keogh L, Smyth P, O'Toole S, Ta R, Gleeson N, O'Leary JJ, Flavin R, Sheils O.

Hum Pathol. 2017 Dec;70:98-104. doi: 10.1016/j.humpath.2017.10.008. Epub 2017 Oct 24.


Peripheral blood microRNA and VEGFA mRNA changes following electroconvulsive therapy: implications for psychotic depression.

Kolshus E, Ryan KM, Blackshields G, Smyth P, Sheils O, McLoughlin DM.

Acta Psychiatr Scand. 2017 Dec;136(6):594-606. doi: 10.1111/acps.12821. Epub 2017 Oct 4.


Managing Weight: What Do People with an Intellectual Disability Want from Mobile Technology?

Smyth P, McDowell C, Leslie JC, Leader G, Donnelly M, Simpson E, Skelly L.

Stud Health Technol Inform. 2017;242:273-278.


Science and data science.

Blei DM, Smyth P.

Proc Natl Acad Sci U S A. 2017 Aug 7. pii: 201702076. doi: 10.1073/pnas.1702076114. [Epub ahead of print]


Iodine in Malt Whisky: A Preliminary Analysis.

Lazarus JH, Smyth PP, Taylor PN, Weibel S, Zimmermann MB.

Thyroid. 2017 Mar;27(3):477-478. doi: 10.1089/thy.2016.0596. Epub 2017 Jan 23. No abstract available.


Iodine Status over Two Decades: Influence of Seaweed Exposure.

Smyth P, Burns R, Casey M, Mullan K, O'Herlihy C, O'Dowd C.

Ir Med J. 2016 Jun 10;109(6):421.


Physicians' attentional performance following a 24-hour observation period: do we need to regulate sleep prior to work?

Smyth P, Maximova K, Jirsch JD.

Occup Environ Med. 2017 Aug;74(8):553-557. doi: 10.1136/oemed-2015-103489. Epub 2016 Nov 1.


The thyroid and breast cancer.

Smyth PP.

Curr Opin Endocrinol Diabetes Obes. 2016 Oct;23(5):389-93. doi: 10.1097/MED.0000000000000273. Review.


Altered expression of mir-222 and mir-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein expression.

Aherne ST, Smyth P, Freeley M, Smith L, Spillane C, O'Leary J, Sheils O.

Int J Mol Med. 2016 Aug;38(2):433-45. doi: 10.3892/ijmm.2016.2653. Epub 2016 Jun 22.


The experiences of emergency department use by street-involved youth: Perspectives of health care and community service providers.

Nicholas DB, Newton AS, Kilmer C, Calhoun A, deJong-Berg MA, Dong K, Hamilton F, McLaughlin AM, Shankar J, Smyth P.

Soc Work Health Care. 2016 Aug;55(7):531-44. doi: 10.1080/00981389.2016.1183553. Epub 2016 Jun 28.


Microscopic Polyangiitis with Spinal Cord Involvement: A Case Report and Review of the Literature.

Decker ML, Emery DJ, Smyth PS, Lu JQ, Lacson A, Yacyshyn E.

J Stroke Cerebrovasc Dis. 2016 Jul;25(7):1696-1704. doi: 10.1016/j.jstrokecerebrovasdis.2016.01.034. Epub 2016 Apr 8. Review.


Pluripotency markers are differentially induced by MEK inhibition in thyroid and melanoma BRAFV600E cell lines.

Dorris ER, Blackshields G, Sommerville G, Alhashemi M, Dias A, McEneaney V, Smyth P, O'Leary JJ, Sheils O.

Cancer Biol Ther. 2016 May 3;17(5):526-42. doi: 10.1080/15384047.2016.1139230. Epub 2016 Feb 1.


Multiple sclerosis in men: management considerations.

Bove R, McHenry A, Hellwig K, Houtchens M, Razaz N, Smyth P, Tremlett H, Sadovnick AD, Rintell D.

J Neurol. 2016 Jul;263(7):1263-73. doi: 10.1007/s00415-015-8005-z. Epub 2016 Jan 2. Review.


Ensuring Effective Prevention of Iodine Deficiency Disorders.

Völzke H, Caron P, Dahl L, de Castro JJ, Erlund I, Gaberšček S, Gunnarsdottir I, Hubalewska-Dydejczyk A, Ittermann T, Ivanova L, Karanfilski B, Khattak RM, Kusić Z, Laurberg P, Lazarus JH, Markou KB, Moreno-Reyes R, Nagy EV, Peeters RP, Pīrāgs V, Podoba J, Rayman MP, Rochau U, Siebert U, Smyth PP, Thuesen BH, Troen A, Vila L, Vitti P, Zamrazil V, Zimmermann MB.

Thyroid. 2016 Feb;26(2):189-96. doi: 10.1089/thy.2015.0543. Epub 2016 Jan 25. Erratum in: Thyroid. 2016 Aug;26(8):1148.


Content Coding of Psychotherapy Transcripts Using Labeled Topic Models.

Gaut G, Steyvers M, Imel ZE, Atkins DC, Smyth P.

IEEE J Biomed Health Inform. 2017 Mar;21(2):476-487. doi: 10.1109/JBHI.2015.2503985. Epub 2015 Nov 25.


Interleukin-15 is associated with disease severity in viral bronchiolitis.

Leahy TR, McManus R, Doherty DG, Grealy R, Coulter T, Smyth P, Blackshields G, Sheils O, Carr MJ, Purandare N, Geary M, Hodemaekers HM, Janssen R, Bont L, Slattery D, Ryan T.

Eur Respir J. 2016 Jan;47(1):212-22. doi: 10.1183/13993003.00642-2015. Epub 2015 Nov 5.


Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation.

Spence S, Greene MK, Fay F, Hams E, Saunders SP, Hamid U, Fitzgerald M, Beck J, Bains BK, Smyth P, Themistou E, Small DM, Schmid D, O'Kane CM, Fitzgerald DC, Abdelghany SM, Johnston JA, Fallon PG, Burrows JF, McAuley DF, Kissenpfennig A, Scott CJ.

Sci Transl Med. 2015 Sep 2;7(303):303ra140. doi: 10.1126/scitranslmed.aab3459.


Bias in counseling of seizure patients following a transient impairment of consciousness: differential adherence to driver fitness guidelines.

Jirsch J, Siddiqi M, Smyth P, Maximova K.

Seizure. 2015 Aug;30:21-5. doi: 10.1016/j.seizure.2015.05.004. Epub 2015 May 12.


Measurement error and outcome distributions: Methodological issues in regression analyses of behavioral coding data.

Holsclaw T, Hallgren KA, Steyvers M, Smyth P, Atkins DC.

Psychol Addict Behav. 2015 Dec;29(4):1031-40. doi: 10.1037/adb0000091. Epub 2015 Jun 22.


Enhanced regulation of cell cycle and suppression of osteoblast differentiation molecular signatures by prostate cancer stem-like holoclones.

Gallagher MF, Salley Y, Spillane CD, Ffrench B, El Baruni S, Blacksheilds G, Smyth P, Martin C, Sheils O, Watson W, O'Leary JJ.

J Clin Pathol. 2015 Sep;68(9):692-702. doi: 10.1136/jclinpath-2015-203001. Epub 2015 Jun 2.


An Association between MicroRNA-21 Expression and Vitamin D Deficiency in Coronary Artery Disease.

Sheane BJ, Smyth P, Scott K, Aziz R, Buckley M, Lodge E, Kiely N, Kingston M, McGovern E, Healy M, Walsh JB, Sheils O, Cunnane G.

Microrna. 2015;4(1):57-63.


Predictors of chronic cerebrospinal venous insufficiency procedure use among older people with multiple sclerosis: a national case-control study.

Ploughman M, Manning OJ, Beaulieu S, Harris C, Hogan SH, Mayo N, Fisk JD, Sadovnick AD, O'Connor P, Morrow SA, Metz LM, Smyth P, Allderdice PW, Scott S, Marrie RA, Stefanelli M, Godwin M.

BMC Health Serv Res. 2015 Apr 16;15:161. doi: 10.1186/s12913-015-0835-y.


Management of multiple sclerosis during pregnancy and the reproductive years: a systematic review.

Bove R, Alwan S, Friedman JM, Hellwig K, Houtchens M, Koren G, Lu E, McElrath TF, Smyth P, Tremlett H, Sadovnick AD.

Obstet Gynecol. 2014 Dec;124(6):1157-68. doi: 10.1097/AOG.0000000000000541. Review.


The co-factor of LIM domains (CLIM/LDB/NLI) maintains basal mammary epithelial stem cells and promotes breast tumorigenesis.

Salmans ML, Yu Z, Watanabe K, Cam E, Sun P, Smyth P, Dai X, Andersen B.

PLoS Genet. 2014 Jul 31;10(7):e1004520. doi: 10.1371/journal.pgen.1004520. eCollection 2014 Jul.


Maternal perchlorate levels in women with borderline thyroid function during pregnancy and the cognitive development of their offspring: data from the Controlled Antenatal Thyroid Study.

Taylor PN, Okosieme OE, Murphy R, Hales C, Chiusano E, Maina A, Joomun M, Bestwick JP, Smyth P, Paradice R, Channon S, Braverman LE, Dayan CM, Lazarus JH, Pearce EN.

J Clin Endocrinol Metab. 2014 Nov;99(11):4291-8. doi: 10.1210/jc.2014-1901. Epub 2014 Jul 24.


The Canadian survey of health, lifestyle and ageing with multiple sclerosis: methodology and initial results.

Ploughman M, Beaulieu S, Harris C, Hogan S, Manning OJ, Alderdice PW, Fisk JD, Sadovnick AD, O'Connor P, Morrow SA, Metz LM, Smyth P, Mayo N, Marrie RA, Knox KB, Stefanelli M, Godwin M.

BMJ Open. 2014 Jul 10;4(7):e005718. doi: 10.1136/bmjopen-2014-005718. Erratum in: BMJ Open. 2015;5(3):e005718.


The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.

d'Adhemar CJ, Spillane CD, Gallagher MF, Bates M, Costello KM, Barry-O'Crowley J, Haley K, Kernan N, Murphy C, Smyth PC, O'Byrne K, Pennington S, Cooke AA, Ffrench B, Martin CM, O'Donnell D, Hennessy B, Stordal B, Finn S, McCann A, Gleeson N, D'Arcy T, Flood B, O'Neill LA, Sheils O, O'Toole S, O'Leary JJ.

PLoS One. 2014 Jun 30;9(6):e100816. doi: 10.1371/journal.pone.0100816. eCollection 2014. Erratum in: PLoS One. 2014;9(9):e108833.


Regulation of iodide uptake in placental primary cultures.

Burns R, O'Herlihy C, Smyth PP.

Eur Thyroid J. 2013 Dec;2(4):243-51. doi: 10.1159/000356847. Epub 2013 Nov 27.


Scaling up the evaluation of psychotherapy: evaluating motivational interviewing fidelity via statistical text classification.

Atkins DC, Steyvers M, Imel ZE, Smyth P.

Implement Sci. 2014 Apr 24;9:49. doi: 10.1186/1748-5908-9-49.


Prevalence of human papillomavirus in men who have sex with men in the era of an effective vaccine; a call to act.

Sadlier C, Rowley D, Morley D, Surah S, O'Dea S, Delamere S, O'Leary J, Smyth P, Clarke S, Sheils O, Bergin C.

HIV Med. 2014 Sep;15(8):499-504. doi: 10.1111/hiv.12150. Epub 2014 Mar 24.


The average roughness and fractal dimension of articular cartilage during drying.

Smyth PA, Rifkin R, Jackson RL, Hanson RR.

Scanning. 2014 May-Jun;36(3):368-75. doi: 10.1002/sca.21128. Epub 2013 Oct 30.


The Simon task and aging: does acute moderate exercise influence cognitive control?

Joyce J, Smyth PJ, Donnelly AE, Davranche K.

Med Sci Sports Exerc. 2014 Mar;46(3):630-9. doi: 10.1249/MSS.0b013e3182a77980.


Activated eosinophils in association with enteric nerves in inflammatory bowel disease.

Smyth CM, Akasheh N, Woods S, Kay E, Morgan RK, Thornton MA, O'Grady A, Cummins R, Sheils O, Smyth P, Gleich GJ, Murray FM, Costello RW.

PLoS One. 2013 May 22;8(5):e64216. doi: 10.1371/journal.pone.0064216. Print 2013.


Predictive modeling of cardiovascular complications in incident hemodialysis patients.

Ion Titapiccolo J, Ferrario M, Barbieri C, Marcelli D, Mari F, Gatti E, Cerutti S, Smyth P, Signorini MG.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:3943-6. doi: 10.1109/EMBC.2012.6346829.


MIR141 Expression Differentiates Hashimoto Thyroiditis from PTC and Benign Thyrocytes in Irish Archival Thyroid Tissues.

Dorris ER, Smyth P, O'Leary JJ, Sheils O.

Front Endocrinol (Lausanne). 2012 Sep 3;3:102. doi: 10.3389/fendo.2012.00102. eCollection 2012.


Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis.

Geyfman M, Kumar V, Liu Q, Ruiz R, Gordon W, Espitia F, Cam E, Millar SE, Smyth P, Ihler A, Takahashi JS, Andersen B.

Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11758-63. doi: 10.1073/pnas.1209592109. Epub 2012 Jul 2.


The fractal structure of equine articular cartilage.

Smyth PA, Rifkin RE, Jackson RL, Reid Hanson R.

Scanning. 2012 Nov-Dec;34(6):418-26. doi: 10.1002/sca.21026. Epub 2012 Jun 29.


A surface roughness comparison of cartilage in different types of synovial joints.

Smyth PA, Rifkin RE, Jackson RL, Hanson RR.

J Biomech Eng. 2012 Feb;134(2):021006. doi: 10.1115/1.4005934.


Dietary iodine intake in pregnancy: an update.

Smyth P, O'Herlihy C.

Ir Med J. 2012 Jan;105(1):5-6. No abstract available.


Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples.

Gallagher MF, Heffron CC, Laios A, O'Toole SA, Ffrench B, Smyth PC, Flavin RJ, Elbaruni SA, Spillane CD, Martin CM, Sheils OM, O'Leary JJ.

J Ovarian Res. 2012 Jan 19;5(1):2. doi: 10.1186/1757-2215-5-2.


The role of secreted frizzled-related protein 2 expression in prostate cancer.

O'Hurley G, Perry AS, O'Grady A, Loftus B, Smyth P, O'Leary JJ, Sheils O, Fitzpatrick JM, Hewitt SM, Lawler M, Kay EW.

Histopathology. 2011 Dec;59(6):1240-8. doi: 10.1111/j.1365-2559.2011.04073.x.


Platelet adhesion and degranulation induce pro-survival and pro-angiogenic signalling in ovarian cancer cells.

Egan K, Crowley D, Smyth P, O'Toole S, Spillane C, Martin C, Gallagher M, Canney A, Norris L, Conlon N, McEvoy L, Ffrench B, Stordal B, Keegan H, Finn S, McEneaney V, Laios A, Ducrée J, Dunne E, Smith L, Berndt M, Sheils O, Kenny D, O'Leary J.

PLoS One. 2011;6(10):e26125. doi: 10.1371/journal.pone.0026125. Epub 2011 Oct 12.


Iodine status of UK schoolgirls: a cross-sectional survey.

Vanderpump MP, Lazarus JH, Smyth PP, Laurberg P, Holder RL, Boelaert K, Franklyn JA; British Thyroid Association UK Iodine Survey Group.

Lancet. 2011 Jun 11;377(9782):2007-12. doi: 10.1016/S0140-6736(11)60693-4. Epub 2011 Jun 2.


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