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Items: 9

1.

FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression.

Hornsveld M, Smits LMM, Meerlo M, van Amersfoort M, Groot Koerkamp MJA, van Leenen D, Kloet DEA, Holstege FCP, Derksen PWB, Burgering BMT, Dansen TB.

Cancer Res. 2018 Feb 12. doi: 10.1158/0008-5472.CAN-17-2511. [Epub ahead of print]

PMID:
29440168
2.

Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells.

Monzel AS, Smits LM, Hemmer K, Hachi S, Moreno EL, van Wuellen T, Jarazo J, Walter J, Brüggemann I, Boussaad I, Berger E, Fleming RMT, Bolognin S, Schwamborn JC.

Stem Cell Reports. 2017 May 9;8(5):1144-1154. doi: 10.1016/j.stemcr.2017.03.010. Epub 2017 Apr 13.

3.

Nurr1:RXRα heterodimer activation as monotherapy for Parkinson's disease.

Spathis AD, Asvos X, Ziavra D, Karampelas T, Topouzis S, Cournia Z, Qing X, Alexakos P, Smits LM, Dalla C, Rideout HJ, Schwamborn JC, Tamvakopoulos C, Fokas D, Vassilatis DK.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3999-4004. doi: 10.1073/pnas.1616874114. Epub 2017 Mar 27.

4.

FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1).

Kloet DE, Polderman PE, Eijkelenboom A, Smits LM, van Triest MH, van den Berg MC, Groot Koerkamp MJ, van Leenen D, Lijnzaad P, Holstege FC, Burgering BM.

Biochem J. 2015 Jul 15;469(2):289-98. doi: 10.1042/BJ20140831. Epub 2015 May 20.

5.

FOXO3 selectively amplifies enhancer activity to establish target gene regulation.

Eijkelenboom A, Mokry M, Smits LM, Nieuwenhuis EE, Burgering BM.

Cell Rep. 2013 Dec 26;5(6):1664-78. doi: 10.1016/j.celrep.2013.11.031. Epub 2013 Dec 19.

6.

Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling.

Eijkelenboom A, Mokry M, de Wit E, Smits LM, Polderman PE, van Triest MH, van Boxtel R, Schulze A, de Laat W, Cuppen E, Burgering BM.

Mol Syst Biol. 2013;9:638. doi: 10.1038/msb.2012.74.

7.

Oxidative stress-dependent regulation of Forkhead box O4 activity by nemo-like kinase.

Szypowska AA, de Ruiter H, Meijer LA, Smits LM, Burgering BM.

Antioxid Redox Signal. 2011 Feb 15;14(4):563-78. doi: 10.1089/ars.2010.3243. Epub 2010 Nov 23.

PMID:
20874444
8.

Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity.

Dansen TB, Smits LM, van Triest MH, de Keizer PL, van Leenen D, Koerkamp MG, Szypowska A, Meppelink A, Brenkman AB, Yodoi J, Holstege FC, Burgering BM.

Nat Chem Biol. 2009 Sep;5(9):664-72. doi: 10.1038/nchembio.194. Epub 2009 Aug 2.

PMID:
19648934
9.

Interaction of FOXO with beta-catenin inhibits beta-catenin/T cell factor activity.

Hoogeboom D, Essers MA, Polderman PE, Voets E, Smits LM, Burgering BM.

J Biol Chem. 2008 Apr 4;283(14):9224-30. doi: 10.1074/jbc.M706638200. Epub 2008 Feb 4.

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