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Items: 1 to 50 of 401

1.

KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer.

Knight JF, Sung VYC, Kuzmin E, Couzens AL, de Verteuil DA, Ratcliffe CDH, Coelho PP, Johnson RM, Samavarchi-Tehrani P, Gruosso T, Smith HW, Lee W, Saleh SM, Zuo D, Zhao H, Guiot MC, Davis RR, Gregg JP, Moraes C, Gingras AC, Park M.

Cell Rep. 2018 Mar 20;22(12):3191-3205. doi: 10.1016/j.celrep.2018.02.095.

2.

Integration of Distinct ShcA Signaling Complexes Promotes Breast Tumor Growth and Tyrosine Kinase Inhibitor Resistance.

Ha JR, Ahn R, Smith HW, Sabourin V, Hébert S, Cepeda Cañedo E, Im YK, Kleinman CL, Muller WJ, Ursini-Siegel J.

Mol Cancer Res. 2018 Feb 16. doi: 10.1158/1541-7786.MCR-17-0623. [Epub ahead of print]

PMID:
29453318
3.

LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis.

Ngan E, Stoletov K, Smith HW, Common J, Muller WJ, Lewis JD, Siegel PM.

Nat Commun. 2017 Apr 24;8:15059. doi: 10.1038/ncomms15059.

4.

ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer.

Deblois G, Smith HW, Tam IS, Gravel SP, Caron M, Savage P, Labbé DP, Bégin LR, Tremblay ML, Park M, Bourque G, St-Pierre J, Muller WJ, Giguère V.

Nat Commun. 2016 Jul 12;7:12156. doi: 10.1038/ncomms12156.

6.

The Daniel K. Inouye College of Pharmacy Scripts: Transition from Traditional to Western Medicine in Hawai'i (Part 1).

Smith HW, Ma C.

Hawaii J Med Public Health. 2016 Mar;75(3):87-9. No abstract available.

7.

Big data in pharmacy practice: current use, challenges, and the future.

Ma C, Smith HW, Chu C, Juarez DT.

Integr Pharm Res Pract. 2015 Aug 6;4:91-99. doi: 10.2147/IPRP.S55862. eCollection 2015. Review.

8.

Chronic Toxicity and Carcinogenicity Studies of the Long-Acting GLP-1 Receptor Agonist Dulaglutide in Rodents.

Byrd RA, Sorden SD, Ryan T, Pienkowski T, LaRock R, Quander R, Wijsman JA, Smith HW, Blackbourne JL, Rosol TJ, Long GG, Martin JA, Vahle JL.

Endocrinology. 2015 Jul;156(7):2417-28. doi: 10.1210/en.2014-1722. Epub 2015 Apr 10.

PMID:
25860029
9.

Effects of Dulaglutide on Thyroid C Cells and Serum Calcitonin in Male Monkeys.

Vahle JL, Byrd RA, Blackbourne JL, Martin JA, Sorden SD, Ryan T, Pienkowski T, Wijsman JA, Smith HW, Rosol TJ.

Endocrinology. 2015 Jul;156(7):2409-16. doi: 10.1210/en.2014-1717. Epub 2015 Apr 10.

PMID:
25860028
10.

Nonclinical safety biomarkers of drug-induced vascular injury: current status and blueprint for the future.

Mikaelian I, Cameron M, Dalmas DA, Enerson BE, Gonzalez RJ, Guionaud S, Hoffmann PK, King NM, Lawton MP, Scicchitano MS, Smith HW, Thomas RA, Weaver JL, Zabka TS; Vascular Injury Working Group of the Predictive Safety Consortium.

Toxicol Pathol. 2014 Jun;42(4):635-57. doi: 10.1177/0192623314525686. Epub 2014 Apr 28.

PMID:
24777748
11.
12.

Transgenic mouse models--a seminal breakthrough in oncogene research.

Smith HW, Muller WJ.

Cold Spring Harb Protoc. 2013 Dec 1;2013(12):1099-108. doi: 10.1101/pdb.top069765. Review.

PMID:
24298026
13.

LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys.

Adams AC, Halstead CA, Hansen BC, Irizarry AR, Martin JA, Myers SR, Reynolds VL, Smith HW, Wroblewski VJ, Kharitonenkov A.

PLoS One. 2013 Jun 18;8(6):e65763. doi: 10.1371/journal.pone.0065763. Print 2013.

14.

Reducing the risk of surgical site infections: did we really think SCIP was going to lead us to the promised land?

Edmiston CE, Spencer M, Lewis BD, Brown KR, Rossi PJ, Henen CR, Smith HW, Seabrook GR.

Surg Infect (Larchmt). 2011 Jun;12(3):169-77. doi: 10.1089/sur.2011.036. Epub 2011 Jul 18.

PMID:
21767147
15.

Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis.

Marcotte R, Smith HW, Sanguin-Gendreau V, McDonough RV, Muller WJ.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2808-13. doi: 10.1073/pnas.1018861108. Epub 2011 May 31.

16.

A comparison of mortality and cardiac biomarker response between three outbred stocks of Sprague Dawley rats treated with isoproterenol.

Schultze AE, Main BW, Hall DG, Hoffman WP, Lee HY, Ackermann BL, Pritt ML, Smith HW.

Toxicol Pathol. 2011 Jun;39(4):576-88. doi: 10.1177/0192623311402219. Epub 2011 Apr 5.

PMID:
21467541
17.

Summary of confirmation cut point discussions.

Smith HW, Moxness M, Marsden R.

AAPS J. 2011 Jun;13(2):227-9. doi: 10.1208/s12248-011-9263-z. Epub 2011 Mar 5.

18.

Regulation of cell signalling by uPAR.

Smith HW, Marshall CJ.

Nat Rev Mol Cell Biol. 2010 Jan;11(1):23-36. doi: 10.1038/nrm2821. Review.

PMID:
20027185
19.

Electrochemiluminescent immunoassay for rat skeletal troponin I (Tnni2) in serum.

Sun D, Hamlin D, Butterfield A, Watson DE, Smith HW.

J Pharmacol Toxicol Methods. 2010 Jan-Feb;61(1):52-8. doi: 10.1016/j.vascn.2009.09.002. Epub 2009 Sep 26.

PMID:
19788923
20.

Preclinical immunogenicity testing for recombinant therapeutic proteins.

Smith HW, Wierda D.

J Immunotoxicol. 2005 Oct 1;2(4):203-10. doi: 10.1080/15476910500362911.

PMID:
18958675
21.

uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.

Smith HW, Marra P, Marshall CJ.

J Cell Biol. 2008 Aug 25;182(4):777-90. doi: 10.1083/jcb.200712050.

22.

Roundtable: discussion of "the difficult patient".

Connell BF, Gunter J, Mayer T, Miller S, Segal J, Smith HW, Tardy E, Waldman SR, Chatham DR.

Facial Plast Surg Clin North Am. 2008 May;16(2):249-58, viii. doi: 10.1016/j.fsc.2007.11.015.

PMID:
18355713
23.

The difficult patient and doctor: origins and suggestions.

Smith HW.

Facial Plast Surg Clin North Am. 2008 May;16(2):177-8, vi. doi: 10.1016/j.fsc.2007.11.004.

PMID:
18355700
24.

Recommendations on risk-based strategies for detection and characterization of antibodies against biotechnology products.

Koren E, Smith HW, Shores E, Shankar G, Finco-Kent D, Rup B, Barrett YC, Devanarayan V, Gorovits B, Gupta S, Parish T, Quarmby V, Moxness M, Swanson SJ, Taniguchi G, Zuckerman LA, Stebbins CC, Mire-Sluis A.

J Immunol Methods. 2008 Apr 20;333(1-2):1-9. doi: 10.1016/j.jim.2008.01.001. Epub 2008 Jan 29. Review.

PMID:
18275969
26.

Glycoform composition profiling of O-glycopeptides derived from human serum IgA1 by matrix-assisted laser desorption ionization-time of flight-mass spectrometry.

Pouria S, Corran PH, Smith AC, Smith HW, Hendry BM, Challacombe SJ, Tarelli E.

Anal Biochem. 2004 Jul 15;330(2):257-63.

PMID:
15203331
27.

A Homeric view of kidney evolution: A reprint of H.W. Smith's classic essay with a new introduction. Evolution of the kidney. 1943.

Vize PD, Smith HW.

Anat Rec A Discov Mol Cell Evol Biol. 2004 Apr;277(2):344-54. No abstract available.

28.

A predictive F344 rat immunotoxicology model: cellular parameters combined with humoral response to NP-CgammaG and KLH.

Smith HW, Winstead CJ, Stank KK, Halstead BW, Wierda D.

Toxicology. 2003 Dec 15;194(1-2):129-45.

PMID:
14636702
29.

Propylene glycol-associated renal toxicity from lorazepam infusion.

Yaucher NE, Fish JT, Smith HW, Wells JA.

Pharmacotherapy. 2003 Sep;23(9):1094-9.

PMID:
14524641
30.

Stimulation of the weak ATPase activity of human hsp90 by a client protein.

McLaughlin SH, Smith HW, Jackson SE.

J Mol Biol. 2002 Jan 25;315(4):787-98.

PMID:
11812147
31.

Mucocele of the frontal sinus: an external approach with frontonasal passage reconstruction.

Yanagisawa E, Joe JK, Smith HW.

Ear Nose Throat J. 2000 Dec;79(12):912-4. No abstract available.

PMID:
11191428
32.

Immunogenicity of biopharmaceuticals in laboratory animals.

Wierda D, Smith HW, Zwickl CM.

Toxicology. 2001 Feb 2;158(1-2):71-4. Review.

PMID:
11164995
33.

Immunogenicity of tissue plasminogen activators in rhesus monkeys: antibody formation and effects on blood level and enzymatic activity.

Zwickl CM, Hughes BL, Piroozi KS, Smith HW, Wierda D.

Fundam Appl Toxicol. 1996 Apr;30(2):243-54.

PMID:
8812272
34.
35.

Discovery, synthesis, and bioactivity of bis(heteroaryl)piperazines. 1. A novel class of non-nucleoside HIV-1 reverse transcriptase inhibitors.

Romero DL, Morge RA, Biles C, Berrios-Pena N, May PD, Palmer JR, Johnson PD, Smith HW, Busso M, Tan CK, et al.

J Med Chem. 1994 Apr 1;37(7):999-1014.

PMID:
7512142
36.

Cleft lip and palate surgery in La Ceiba, Honduras.

Smith HW, Keen M, Edwards E.

Arch Otolaryngol Head Neck Surg. 1991 Dec;117(12):1356-9.

PMID:
1845261
37.
38.

Contribution of leukotriene B4 to airway inflammation and the effect of antagonists.

Richards IM, Sun FF, Taylor BM, Shields SK, Griffin RL, Morris J, Wishka DG, Smith HW, Johnson RA, Dunn CJ.

Ann N Y Acad Sci. 1991;629:274-87.

PMID:
1659282
39.

Biochemical manifestations of oxygen toxicity in the newborn lamb.

Hansen TN, Smith CV, Gest AL, Smith HW, Giesler M.

Pediatr Res. 1990 Dec;28(6):613-7.

PMID:
2284160
40.

Somatotropin antibody formation in cows treated with a recombinant bovine somatotropin over two lactations.

Zwickl CM, Smith HW, Tamura RN, Bick PH.

J Dairy Sci. 1990 Oct;73(10):2888-95.

PMID:
2283416
41.

The politics of abortion: husband notification legislation, self-disclosure, and marital bargaining.

Smith HW, Kronauge C.

Sociol Q. 1990 Winter;31(4):585-98. No abstract available.

PMID:
11659352
42.

Protein crystal growth in microgravity.

DeLucas LJ, Smith CD, Smith HW, Vijay-Kumar S, Senadhi SE, Ealick SE, Carter DC, Snyder RS, Weber PC, Salemme FR, et al.

Science. 1989 Nov 3;246(4930):651-4. Erratum in: Science 1990 Sep 21;249(4975):1359.

43.

Formation of lipoxygenase products of arachidonate metabolism in disaggregated lung cells.

Bach MK, Brashler JR, Smith HW.

Prog Clin Biol Res. 1989;297:27-37; discussion 37-8. No abstract available.

PMID:
2511574
44.

Ethical use of Yellow Pages listings by physicians.

Denenberg SM, Smith HW.

Arch Otolaryngol Head Neck Surg. 1988 Dec;114(12):1392-4.

PMID:
3190865
45.

The nasal septum and restless sleep.

Kirchner JA, Smith HW.

Conn Med. 1988 Mar;52(3):131-3. No abstract available.

PMID:
3359771
46.

Acute myocardial infarction temporally related to cocaine use. Clinical, angiographic, and pathophysiologic observations.

Smith HW 3rd, Liberman HA, Brody SL, Battey LL, Donohue BC, Morris DC.

Ann Intern Med. 1987 Jul;107(1):13-8.

PMID:
3592445
47.
48.

The control of experimental Escherichia coli diarrhoea in calves by means of bacteriophages.

Smith HW, Huggins MB, Shaw KM.

J Gen Microbiol. 1987 May;133(5):1111-26.

49.

Two toxin-converting phages from Escherichia coli O157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities.

Strockbine NA, Marques LR, Newland JW, Smith HW, Holmes RK, O'Brien AD.

Infect Immun. 1986 Jul;53(1):135-40.

50.

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