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Items: 7


[Relevance of big data for molecular diagnostics].

Bonin-Andresen M, Smiljanovic B, Stuhlmüller B, Sörensen T, Grützkau A, Häupl T.

Z Rheumatol. 2018 Apr;77(3):195-202. doi: 10.1007/s00393-018-0436-3. Review. German.


Monocyte alterations in rheumatoid arthritis are dominated by preterm release from bone marrow and prominent triggering in the joint.

Smiljanovic B, Radzikowska A, Kuca-Warnawin E, Kurowska W, Grün JR, Stuhlmüller B, Bonin M, Schulte-Wrede U, Sörensen T, Kyogoku C, Bruns A, Hermann S, Ohrndorf S, Aupperle K, Backhaus M, Burmester GR, Radbruch A, Grützkau A, Maslinski W, Häupl T.

Ann Rheum Dis. 2018 Feb;77(2):300-308. doi: 10.1136/annrheumdis-2017-211649. Epub 2017 Nov 30.


Genomic stratification by expression of HLA-DRB4 alleles identifies differential innate and adaptive immune transcriptional patterns - A strategy to detect predictors of methotrexate response in early rheumatoid arthritis.

Stuhlmüller B, Mans K, Tandon N, Bonin MO, Smiljanovic B, Sörensen TA, Schendel P, Martus P, Listing J, Detert J, Backhaus M, Neumann T, Winchester RJ, Burmester GR, Häupl T.

Clin Immunol. 2016 Oct;171:50-61. doi: 10.1016/j.clim.2016.08.013. Epub 2016 Aug 26.


Upregulation of immunoproteasome subunits in myositis indicates active inflammation with involvement of antigen presenting cells, CD8 T-cells and IFNΓ.

Ghannam K, Martinez-Gamboa L, Spengler L, Krause S, Smiljanovic B, Bonin M, Bhattarai S, Grützkau A, Burmester GR, Häupl T, Feist E.

PLoS One. 2014 Aug 6;9(8):e104048. doi: 10.1371/journal.pone.0104048. eCollection 2014.


Cell-specific type I IFN signatures in autoimmunity and viral infection: what makes the difference?

Kyogoku C, Smiljanovic B, Grün JR, Biesen R, Schulte-Wrede U, Häupl T, Hiepe F, Alexander T, Radbruch A, Grützkau A.

PLoS One. 2013 Dec 31;8(12):e83776. doi: 10.1371/journal.pone.0083776. eCollection 2013.


The multifaceted balance of TNF-α and type I/II interferon responses in SLE and RA: how monocytes manage the impact of cytokines.

Smiljanovic B, Grün JR, Biesen R, Schulte-Wrede U, Baumgrass R, Stuhlmüller B, Maslinski W, Hiepe F, Burmester GR, Radbruch A, Häupl T, Grützkau A.

J Mol Med (Berl). 2012 Nov;90(11):1295-309. doi: 10.1007/s00109-012-0907-y. Epub 2012 May 19.


Defining TNF-α- and LPS-induced gene signatures in monocytes to unravel the complexity of peripheral blood transcriptomes in health and disease.

Smiljanovic B, Grün JR, Steinbrich-Zöllner M, Stuhlmüller B, Häupl T, Burmester GR, Radbruch A, Grützkau A, Baumgrass R.

J Mol Med (Berl). 2010 Oct;88(10):1065-79. doi: 10.1007/s00109-010-0648-8. Epub 2010 Jul 17.


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