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Items: 1 to 50 of 155

1.

Influence of induction chemotherapy in trimodality therapy-eligible oesophageal cancer patients: secondary analysis of a randomised trial.

Shimodaira Y, Slack RS, Harada K, Chen HC, Sagebiel T, Bhutani MS, Lee JH, Weston B, Elimova E, Lin Q, Amlashi FG, Mizrak Kaya D, Blum MA, Roth JA, Swisher SG, Skinner HD, Hofstetter WL, Rogers JE, Mares J, Thomas I, Maru DM, Komaki R, Walsh G, Ajani JA.

Br J Cancer. 2018 Feb 6;118(3):331-337. doi: 10.1038/bjc.2017.423. Epub 2017 Dec 12.

PMID:
29235564
2.

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.

Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, Jekabsons MB, Jonas EA, Jordán J, Lipton SA, Manfredi G, Mattson MP, McLaughlin B, Methner A, Murphy AN, Murphy MP, Nicholls DG, Polster BM, Pozzan T, Rizzuto R, Satrústegui J, Slack RS, Swanson RA, Swerdlow RH, Will Y, Ying Z, Joselin A, Gioran A, Moreira Pinho C, Watters O, Salvucci M, Llorente-Folch I, Park DS, Bano D, Ankarcrona M, Pizzo P, Prehn JHM.

Cell Death Differ. 2017 Dec 11. doi: 10.1038/s41418-017-0020-4. [Epub ahead of print] Review.

PMID:
29229998
3.

Assessment of Ileostomy Output Using Telemedicine: A Feasibility Trial.

Bednarski BK, Slack RS, Katz M, You YN, Papadopolous J, Rodriguez-Bigas MA, Skibber JM, Matin SF, Chang GJ.

Dis Colon Rectum. 2018 Jan;61(1):77-83. doi: 10.1097/DCR.0000000000000945.

PMID:
29215474
4.

Mitochondrial activity in the regulation of stem cell self-renewal and differentiation.

Khacho M, Slack RS.

Curr Opin Cell Biol. 2017 Dec;49:1-8. doi: 10.1016/j.ceb.2017.11.003. Epub 2017 Nov 22. Review.

PMID:
29175320
5.

Modeling Neuronal Death and Degeneration in Mouse Primary Cerebellar Granule Neurons.

Laaper M, Haque T, Slack RS, Jahani-Asl A.

J Vis Exp. 2017 Nov 6;(129). doi: 10.3791/55871.

PMID:
29155785
6.

Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism.

Thrush AB, Antoun G, Nikpay M, Patten DA, DeVlugt C, Mauger JF, Beauchamp BL, Lau P, Reshke R, Doucet É, Imbeault P, Boushel R, Gibbings D, Hager J, Valsesia A, Slack RS, Al-Dirbashi OY, Dent R, McPherson R, Harper ME.

Int J Obes (Lond). 2017 Nov 20. doi: 10.1038/ijo.2017.286. [Epub ahead of print]

PMID:
29151592
7.

PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress.

Huang E, Qu D, Huang T, Rizzi N, Boonying W, Krolak D, Ciana P, Woulfe J, Klein C, Slack RS, Figeys D, Park DS.

Nat Commun. 2017 Nov 9;8(1):1399. doi: 10.1038/s41467-017-01435-1.

8.

Patterns of relapse in patients with localized gastric adenocarcinoma who had surgery with or without adjunctive therapy: costs and effectiveness of surveillance.

Elimova E, Slack RS, Chen HC, Planjery V, Shiozaki H, Shimodaira Y, Charalampakis N, Lin Q, Harada K, Wadhwa R, Estrella JS, Kaya DM, Sagebiel T, Lee JH, Weston B, Bhutani M, Murphy MB, Matamoros A, Minsky B, Das P, Mansfield PF, Badgwell BD, Ajani JA.

Oncotarget. 2017 Jul 13;8(46):81430-81440. doi: 10.18632/oncotarget.19226. eCollection 2017 Oct 6.

9.

Utility of endoscopic ultrasound-guided fine-needle aspiration of regional lymph nodes that are proximal to and far from the primary distal esophageal carcinoma.

Shimodaira Y, Slack RS, Harada K, Bhutani MS, Elimova E, Staerkel GA, Sneige N, Erasmus J, Shiozaki H, Charalampakis N, Planjery V, Kaya DM, Amlashi FG, Blum MA, Skinner HD, Minsky BD, Maru DM, Hofstetter WL, Swisher SG, Mares JE, Rogers JE, Lin QD, Ross WA, Weston B, Lee JH, Ajani JA.

Oncotarget. 2017 May 23;8(45):79356-79365. doi: 10.18632/oncotarget.18119. eCollection 2017 Oct 3.

10.

Surgical Feeding Tubes in Pediatric and Adolescent Cancer Patients: A Single-institution Retrospective Review.

Hamilton EC, Curtin T, Slack RS, Ge C, Slade AD, Hayes-Jordan A, Lally KP, Austin MT.

J Pediatr Hematol Oncol. 2017 Oct;39(7):e342-e348. doi: 10.1097/MPH.0000000000000902.

PMID:
28678086
11.

Mitochondrial and Reactive Oxygen Species Signaling Coordinate Stem Cell Fate Decisions and Life Long Maintenance.

Khacho M, Slack RS.

Antioxid Redox Signal. 2017 Jul 31. doi: 10.1089/ars.2017.7228. [Epub ahead of print]

PMID:
28657337
12.

Mitochondrial dynamics in the regulation of neurogenesis: From development to the adult brain.

Khacho M, Slack RS.

Dev Dyn. 2018 Jan;247(1):47-53. doi: 10.1002/dvdy.24538. Epub 2017 Jul 13. Review.

PMID:
28643345
13.

Cdc25A Is a Critical Mediator of Ischemic Neuronal Death In Vitro and In Vivo.

Iyirhiaro GO, Im DS, Boonying W, Callaghan SM, During MJ, Slack RS, Park DS.

J Neurosci. 2017 Jul 12;37(28):6729-6740. doi: 10.1523/JNEUROSCI.3017-16.2017. Epub 2017 Jun 12.

14.

Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis.

Khacho M, Clark A, Svoboda DS, MacLaurin JG, Lagace DC, Park DS, Slack RS.

Hum Mol Genet. 2017 Sep 1;26(17):3327-3341. doi: 10.1093/hmg/ddx217.

PMID:
28595361
15.

RB: An essential player in adult neurogenesis.

Fong BC, Slack RS.

Neurogenesis (Austin). 2017 Feb 7;4(1):e1270382. doi: 10.1080/23262133.2016.1270382. eCollection 2017.

16.

LRRK2(I2020T) functional genetic interactors that modify eye degeneration and dopaminergic cell loss in Drosophila.

Marcogliese PC, Abuaish S, Kabbach G, Abdel-Messih E, Seang S, Li G, Slack RS, Haque ME, Venderova K, Park DS.

Hum Mol Genet. 2017 Apr 1;26(7):1247-1257. doi: 10.1093/hmg/ddx030.

PMID:
28158614
17.

Selective Perioperative Administration of Pasireotide is More Cost-Effective Than Routine Administration for Pancreatic Fistula Prophylaxis.

Denbo JW, Slack RS, Bruno M, Cloyd JM, Prakash L, Fleming JB, Kim MP, Aloia TA, Vauthey JN, Lee JE, Katz MH.

J Gastrointest Surg. 2017 Apr;21(4):636-646. doi: 10.1007/s11605-016-3340-7. Epub 2017 Jan 3.

PMID:
28050766
18.

Clonal expansion of CD8 T cells in the systemic circulation precedes development of ipilimumab-induced toxicities.

Subudhi SK, Aparicio A, Gao J, Zurita AJ, Araujo JC, Logothetis CJ, Tahir SA, Korivi BR, Slack RS, Vence L, Emerson RO, Yusko E, Vignali M, Robins HS, Sun J, Allison JP, Sharma P.

Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11919-11924. Epub 2016 Oct 3.

19.

RB regulates the production and the survival of newborn neurons in the embryonic and adult dentate gyrus.

Vandenbosch R, Clark A, Fong BC, Omais S, Jaafar C, Dugal-Tessier D, Dhaliwal J, Lagace DC, Park DS, Ghanem N, Slack RS.

Hippocampus. 2016 Nov;26(11):1379-1392. doi: 10.1002/hipo.22613. Epub 2016 Jul 8.

PMID:
27325572
20.

Clinical risk stratification in patients with surgically resectable micropapillary bladder cancer.

Fernández MI, Williams SB, Willis DL, Slack RS, Dickstein RJ, Parikh S, Chiong E, Siefker-Radtke AO, Guo CC, Czerniak BA, McConkey DJ, Shah JB, Pisters LL, Grossman HB, Dinney CP, Kamat AM.

BJU Int. 2017 May;119(5):684-691. doi: 10.1111/bju.13689. Epub 2016 Nov 11.

PMID:
27753185
21.

Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program.

Khacho M, Clark A, Svoboda DS, Azzi J, MacLaurin JG, Meghaizel C, Sesaki H, Lagace DC, Germain M, Harper ME, Park DS, Slack RS.

Cell Stem Cell. 2016 Aug 4;19(2):232-247. doi: 10.1016/j.stem.2016.04.015. Epub 2016 May 26.

22.

Metastatic Gastroesophageal Adenocarcinoma Patients Treated with Systemic Therapy Followed by Consolidative Local Therapy: A Nomogram Associated with Long-Term Survivors.

Shiozaki H, Slack RS, Chen HC, Elimova E, Planjery V, Charalampakis N, Wadhwa R, Shimodaira Y, Skinner H, Lee JH, Weston B, Bhutani MS, Blum-Murphy M, Rogers JE, Maru DM, Matamoros A Jr, Sagebiel T, Estrella JS, Das P, Hofstetter WL, Mares JE, Mizrak Kaya D, Harada K, Lin Q, Minsky BD, Badgwell BD, Ajani JA.

Oncology. 2016;91(1):55-60. doi: 10.1159/000445998. Epub 2016 Apr 28.

23.

The Role of Metastasectomy in Patients with Renal Cell Carcinoma with Sarcomatoid Dedifferentiation: A Matched Controlled Analysis.

Thomas AZ, Adibi M, Slack RS, Borregales LD, Merrill MM, Tamboli P, Sircar K, Jonasch E, Tannir NM, Matin SF, Wood CG, Karam JA.

J Urol. 2016 Sep;196(3):678-84. doi: 10.1016/j.juro.2016.03.144. Epub 2016 Mar 29.

24.

Forebrain neurogenesis: From embryo to adult.

Dennis D, Picketts D, Slack RS, Schuurmans C.

Trends Dev Biol. 2016 Jan 1;9(1):77-90.

25.

Erratum to: Impaired mitochondrial oxidative phosphorylation and supercomplex assembly in rectus abdominis muscle of diabetic obese individuals.

Antoun G, McMurray F, Thrush AB, Patten DA, Peixoto AC, Slack RS, McPherson R, Dent R, Harper ME.

Diabetologia. 2016 Feb;59(2):396-7. doi: 10.1007/s00125-015-3821-3. No abstract available.

PMID:
26610932
26.

Prognosis of gastric adenocarcinoma patients with various burdens of peritoneal metastases.

Shiozaki H, Elimova E, Slack RS, Chen HC, Staerkel GA, Sneige N, Shimodaira Y, Sagebiel T, Lee JH, Bhutani MS, Das P, Mansfield PF, Estrella JS, Badgwell BD, Ajani JA.

J Surg Oncol. 2016 Jan;113(1):29-35. doi: 10.1002/jso.24087. Epub 2015 Nov 25.

PMID:
26603684
27.

BAG2 Gene-mediated Regulation of PINK1 Protein Is Critical for Mitochondrial Translocation of PARKIN and Neuronal Survival.

Qu D, Hage A, Don-Carolis K, Huang E, Joselin A, Safarpour F, Marcogliese PC, Rousseaux MW, Hewitt SJ, Huang T, Im DS, Callaghan S, Dewar-Darch D, Figeys D, Slack RS, Park DS.

J Biol Chem. 2015 Dec 18;290(51):30441-52. doi: 10.1074/jbc.M115.677815. Epub 2015 Nov 4.

28.

Impaired mitochondrial oxidative phosphorylation and supercomplex assembly in rectus abdominis muscle of diabetic obese individuals.

Antoun G, McMurray F, Thrush AB, Patten DA, Peixoto AC, Slack RS, McPherson R, Dent R, Harper ME.

Diabetologia. 2015 Dec;58(12):2861-6. doi: 10.1007/s00125-015-3772-8. Epub 2015 Sep 24. Erratum in: Diabetologia. 2016 Feb;59(2):396-7.

PMID:
26404066
29.

Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons.

Pacelli C, Giguère N, Bourque MJ, Lévesque M, Slack RS, Trudeau LÉ.

Curr Biol. 2015 Sep 21;25(18):2349-60. doi: 10.1016/j.cub.2015.07.050. Epub 2015 Aug 27.

30.

Early versus Delayed Therapy of Advanced Gastric Cancer Patients--Does It Make a Difference?

Elimova E, Shiozaki H, Slack RS, Chen HC, Wadhwa R, Sudo K, Charalampakis N, Hiremath A, Estrella JS, Matamoros A, Sagebiel T, Das P, Rogers JE, Garris JL, Blum MA, Badgwell B, Ajani JA.

Oncology. 2015;89(4):215-20. doi: 10.1159/000434647. Epub 2015 Jul 8.

31.

Percentage of sarcomatoid component as a prognostic indicator for survival in renal cell carcinoma with sarcomatoid dedifferentiation.

Adibi M, Thomas AZ, Borregales LD, Merrill MM, Slack RS, Chen HC, Sircar K, Murugan P, Tamboli P, Jonasch E, Tannir NM, Matin SF, Wood CG, Karam JA.

Urol Oncol. 2015 Oct;33(10):427.e17-23. doi: 10.1016/j.urolonc.2015.04.011. Epub 2015 May 23.

32.

CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death.

Jahani-Asl A, Huang E, Irrcher I, Rashidian J, Ishihara N, Lagace DC, Slack RS, Park DS.

Hum Mol Genet. 2015 Aug 15;24(16):4573-83. doi: 10.1093/hmg/ddv188. Epub 2015 May 22.

33.

Natural language processing as an alternative to manual reporting of colonoscopy quality metrics.

Raju GS, Lum PJ, Slack RS, Thirumurthi S, Lynch PM, Miller E, Weston BR, Davila ML, Bhutani MS, Shafi MA, Bresalier RS, Dekovich AA, Lee JH, Guha S, Pande M, Blechacz B, Rashid A, Routbort M, Shuttlesworth G, Mishra L, Stroehlein JR, Ross WA.

Gastrointest Endosc. 2015 Sep;82(3):512-9. doi: 10.1016/j.gie.2015.01.049. Epub 2015 Apr 22.

34.

Tissue-specific targeting of cell fate regulatory genes by E2f factors.

Julian LM, Liu Y, Pakenham CA, Dugal-Tessier D, Ruzhynsky V, Bae S, Tsai SY, Leone G, Slack RS, Blais A.

Cell Death Differ. 2016 Apr;23(4):565-75. doi: 10.1038/cdd.2015.36. Epub 2015 Apr 24.

35.

Clinically nonmetastatic renal cell carcinoma with sarcomatoid dedifferentiation: Natural history and outcomes after surgical resection with curative intent.

Merrill MM, Wood CG, Tannir NM, Slack RS, Babaian KN, Jonasch E, Pagliaro LC, Compton Z, Tamboli P, Sircar K, Pisters LL, Matin SF, Karam JA.

Urol Oncol. 2015 Apr;33(4):166.e21-9. doi: 10.1016/j.urolonc.2014.11.021. Epub 2015 Feb 17.

36.

Induction of protein deletion through in utero electroporation to define deficits in neuronal migration in transgenic models.

Svoboda DS, Clark A, Park DS, Slack RS.

J Vis Exp. 2015 Jan 12;(95):51983. doi: 10.3791/51983.

37.

OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand.

Patten DA, Wong J, Khacho M, Soubannier V, Mailloux RJ, Pilon-Larose K, MacLaurin JG, Park DS, McBride HM, Trinkle-Mulcahy L, Harper ME, Germain M, Slack RS.

EMBO J. 2014 Nov 18;33(22):2676-91. doi: 10.15252/embj.201488349. Epub 2014 Oct 8.

38.

DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress.

Parsanejad M, Bourquard N, Qu D, Zhang Y, Huang E, Rousseaux MW, Aleyasin H, Irrcher I, Callaghan S, Vaillant DC, Kim RH, Slack RS, Mak TW, Reddy ST, Figeys D, Park DS.

PLoS One. 2014 Sep 11;9(9):e106601. doi: 10.1371/journal.pone.0106601. eCollection 2014.

39.

A phase II, randomized, double blind trial of calcium aluminosilicate clay versus placebo for the prevention of diarrhea in patients with metastatic colorectal cancer treated with irinotecan.

Kee BK, Morris JS, Slack RS, Crocenzi T, Wong L, Esparaz B, Overman M, Glover K, Jones D, Wen S, Fisch MJ.

Support Care Cancer. 2015 Mar;23(3):661-70. doi: 10.1007/s00520-014-2402-1. Epub 2014 Aug 27.

PMID:
25160493
40.

Regulation of the VHL/HIF-1 pathway by DJ-1.

Parsanejad M, Zhang Y, Qu D, Irrcher I, Rousseaux MW, Aleyasin H, Kamkar F, Callaghan S, Slack RS, Mak TW, Lee S, Figeys D, Park DS.

J Neurosci. 2014 Jun 4;34(23):8043-50. doi: 10.1523/JNEUROSCI.1244-13.2014.

41.

Regulation of ischemic neuronal death by E2F4-p130 protein complexes.

Iyirhiaro GO, Zhang Y, Estey C, O'Hare MJ, Safarpour F, Parsanejad M, Wang S, Abdel-Messih E, Callaghan SM, During MJ, Slack RS, Park DS.

J Biol Chem. 2014 Jun 27;289(26):18202-13. doi: 10.1074/jbc.M114.574145. Epub 2014 May 14.

42.

Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival.

Khacho M, Tarabay M, Patten D, Khacho P, MacLaurin JG, Guadagno J, Bergeron R, Cregan SP, Harper ME, Park DS, Slack RS.

Nat Commun. 2014 Apr 1;5:3550. doi: 10.1038/ncomms4550.

43.

Pocket proteins pRb and p107 are required for cortical lamination independent of apoptosis.

Svoboda DS, Paquin A, Park DS, Slack RS.

Dev Biol. 2013 Dec 1;384(1):101-13. doi: 10.1016/j.ydbio.2013.09.015. Epub 2013 Sep 19.

44.

Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1.

Tripathi DN, Chowdhury R, Trudel LJ, Tee AR, Slack RS, Walker CL, Wogan GN.

Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):E2950-7. doi: 10.1073/pnas.1307736110. Epub 2013 Jul 22.

45.

A focused curriculum in surgical oncology for the third-year medical students.

Wisniewski WR, Fournier KF, Ling YK, Slack RS, Babiera G, Grubbs EG, Moore LJ, Fleming JB, You YN.

J Surg Res. 2013 Dec;185(2):555-60. doi: 10.1016/j.jss.2013.06.019. Epub 2013 Jul 1.

PMID:
23845865
46.

Interaction and antagonistic roles of NF-κB and Hes6 in the regulation of cortical neurogenesis.

Methot L, Hermann R, Tang Y, Lo R, Al-Jehani H, Jhas S, Svoboda D, Slack RS, Barker PA, Stifani S.

Mol Cell Biol. 2013 Jul;33(14):2797-808. doi: 10.1128/MCB.01610-12. Epub 2013 May 20.

47.

Comparison of the utility of covered metal stents versus uncovered metal stents in the management of malignant biliary strictures in 749 patients.

Lee JH, Krishna SG, Singh A, Ladha HS, Slack RS, Ramireddy S, Raju GS, Davila M, Ross WA.

Gastrointest Endosc. 2013 Aug;78(2):312-24. doi: 10.1016/j.gie.2013.02.032. Epub 2013 Apr 13.

PMID:
23591331
48.

LXCXE-independent chromatin remodeling by Rb/E2f mediates neuronal quiescence.

Andrusiak MG, Vandenbosch R, Dick FA, Park DS, Slack RS.

Cell Cycle. 2013 May 1;12(9):1416-23. doi: 10.4161/cc.24527. Epub 2013 Apr 9.

49.

Perturbation of transcription factor Nur77 expression mediated by myocyte enhancer factor 2D (MEF2D) regulates dopaminergic neuron loss in response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

Mount MP, Zhang Y, Amini M, Callaghan S, Kulczycki J, Mao Z, Slack RS, Anisman H, Park DS.

J Biol Chem. 2013 May 17;288(20):14362-71. doi: 10.1074/jbc.M112.439216. Epub 2013 Mar 27.

50.

Conditional disruption of calpain in the CNS alters dendrite morphology, impairs LTP, and promotes neuronal survival following injury.

Amini M, Ma CL, Farazifard R, Zhu G, Zhang Y, Vanderluit J, Zoltewicz JS, Hage F, Savitt JM, Lagace DC, Slack RS, Beique JC, Baudry M, Greer PA, Bergeron R, Park DS.

J Neurosci. 2013 Mar 27;33(13):5773-84. doi: 10.1523/JNEUROSCI.4247-12.2013.

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