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Items: 31


Integrative testis transcriptome analysis reveals differentially expressed miRNAs and their mRNA targets during early puberty in Atlantic salmon.

Skaftnesmo KO, Edvardsen RB, Furmanek T, Crespo D, Andersson E, Kleppe L, Taranger GL, Bogerd J, Schulz RW, Wargelius A.

BMC Genomics. 2017 Oct 18;18(1):801. doi: 10.1186/s12864-017-4205-5.


Divergent Activity of the Pseudogene PTENP1 in ER-Positive and Negative Breast Cancer.

Yndestad S, Austreid E, Skaftnesmo KO, Lønning PE, Eikesdal HP.

Mol Cancer Res. 2018 Jan;16(1):78-89. doi: 10.1158/1541-7786.MCR-17-0207. Epub 2017 Oct 11.


Sex steroid production associated with puberty is absent in germ cell-free salmon.

Kleppe L, Andersson E, Skaftnesmo KO, Edvardsen RB, Fjelldal PG, Norberg B, Bogerd J, Schulz RW, Wargelius A.

Sci Rep. 2017 Oct 3;7(1):12584. doi: 10.1038/s41598-017-12936-w.


Dnd knockout ablates germ cells and demonstrates germ cell independent sex differentiation in Atlantic salmon.

Wargelius A, Leininger S, Skaftnesmo KO, Kleppe L, Andersson E, Taranger GL, Schulz RW, Edvardsen RB.

Sci Rep. 2016 Feb 18;6:21284. doi: 10.1038/srep21284.


A Novel Nanoprobe for Multimodal Imaging Is Effectively Incorporated into Human Melanoma Metastatic Cell Lines.

Aasen SN, Pospisilova A, Eichler TW, Panek J, Hruby M, Stepanek P, Spriet E, Jirak D, Skaftnesmo KO, Thorsen F.

Int J Mol Sci. 2015 Sep 8;16(9):21658-80. doi: 10.3390/ijms160921658.


Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes.

Burtey A, Wagner M, Hodneland E, Skaftnesmo KO, Schoelermann J, Mondragon IR, Espedal H, Golebiewska A, Niclou SP, Bjerkvig R, Kögel T, Gerdes HH.

FASEB J. 2015 Nov;29(11):4695-712. doi: 10.1096/fj.14-268615. Epub 2015 Jul 28.


Melanoma brain metastasis is independent of lactate dehydrogenase A expression.

Sundstrøm T, Espedal H, Harter PN, Fasmer KE, Skaftnesmo KO, Horn S, Hodneland E, Mittelbronn M, Weide B, Beschorner R, Bender B, Rygh CB, Lund-Johansen M, Bjerkvig R, Thorsen F.

Neuro Oncol. 2015 Oct;17(10):1374-85. doi: 10.1093/neuonc/nov040. Epub 2015 Mar 19.


A co-culture model with brain tumor-specific bioluminescence demonstrates astrocyte-induced drug resistance in glioblastoma.

Yang N, Yan T, Zhu H, Liang X, Leiss L, Sakariassen PØ, Skaftnesmo KO, Huang B, Costea DE, Enger PØ, Li X, Wang J.

J Transl Med. 2014 Oct 4;12:278. doi: 10.1186/s12967-014-0278-y.


Targeted mutagenesis in Atlantic salmon (Salmo salar L.) using the CRISPR/Cas9 system induces complete knockout individuals in the F0 generation.

Edvardsen RB, Leininger S, Kleppe L, Skaftnesmo KO, Wargelius A.

PLoS One. 2014 Sep 25;9(9):e108622. doi: 10.1371/journal.pone.0108622. eCollection 2014.


In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways.

Daphu I, Horn S, Stieber D, Varughese JK, Spriet E, Dale HA, Skaftnesmo KO, Bjerkvig R, Thorsen F.

Int J Mol Sci. 2014 May 16;15(5):8773-94. doi: 10.3390/ijms15058773.


Multimodal imaging enables early detection and characterization of changes in tumor permeability of brain metastases.

Thorsen F, Fite B, Mahakian LM, Seo JW, Qin S, Harrison V, Johnson S, Ingham E, Caskey C, Sundstrøm T, Meade TJ, Harter PN, Skaftnesmo KO, Ferrara KW.

J Control Release. 2013 Dec 28;172(3):812-22. doi: 10.1016/j.jconrel.2013.10.019. Epub 2013 Oct 29.


Targeting glioblastoma with NK cells and mAb against NG2/CSPG4 prolongs animal survival.

Poli A, Wang J, Domingues O, Planagumà J, Yan T, Rygh CB, Skaftnesmo KO, Thorsen F, McCormack E, Hentges F, Pedersen PH, Zimmer J, Enger PØ, Chekenya M.

Oncotarget. 2013 Sep;4(9):1527-46.


In vivo bioluminescence imaging validation of a human biopsy-derived orthotopic mouse model of glioblastoma multiforme.

Jarzabek MA, Huszthy PC, Skaftnesmo KO, McCormack E, Dicker P, Prehn JH, Bjerkvig R, Byrne AT.

Mol Imaging. 2013 May;12(3):161-72.


EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis.

Talasila KM, Soentgerath A, Euskirchen P, Rosland GV, Wang J, Huszthy PC, Prestegarden L, Skaftnesmo KO, Sakariassen PØ, Eskilsson E, Stieber D, Keunen O, Brekka N, Moen I, Nigro JM, Vintermyr OK, Lund-Johansen M, Niclou S, Mørk SJ, Enger PO, Bjerkvig R, Miletic H.

Acta Neuropathol. 2013 May;125(5):683-98. doi: 10.1007/s00401-013-1101-1. Epub 2013 Feb 22.


Automated tracking of nanoparticle-labeled melanoma cells improves the predictive power of a brain metastasis model.

Sundstrøm T, Daphu I, Wendelbo I, Hodneland E, Lundervold A, Immervoll H, Skaftnesmo KO, Babic M, Jendelova P, Sykova E, Lund-Johansen M, Bjerkvig R, Thorsen F.

Cancer Res. 2013 Apr 15;73(8):2445-56. doi: 10.1158/0008-5472.CAN-12-3514. Epub 2013 Feb 19.


MicroRNA regulation of the synaptic plasticity-related gene Arc.

Wibrand K, Pai B, Siripornmongcolchai T, Bittins M, Berentsen B, Ofte ML, Weigel A, Skaftnesmo KO, Bramham CR.

PLoS One. 2012;7(7):e41688. doi: 10.1371/journal.pone.0041688. Epub 2012 Jul 26.


Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide.

Yan T, Skaftnesmo KO, Leiss L, Sleire L, Wang J, Li X, Enger PØ.

BMC Cancer. 2011 Dec 20;11:524. doi: 10.1186/1471-2407-11-524.


NUMB does not impair growth and differentiation status of experimental gliomas.

Euskirchen P, Skaftnesmo KO, Huszthy PC, Brekkå N, Bjerkvig R, Jacobs AH, Miletic H.

Exp Cell Res. 2011 Dec 10;317(20):2864-73. doi: 10.1016/j.yexcr.2011.09.002. Epub 2011 Sep 12.


Targeting the NG2/CSPG4 proteoglycan retards tumour growth and angiogenesis in preclinical models of GBM and melanoma.

Wang J, Svendsen A, Kmiecik J, Immervoll H, Skaftnesmo KO, Planagumà J, Reed RK, Bjerkvig R, Miletic H, Enger PØ, Rygh CB, Chekenya M.

PLoS One. 2011;6(7):e23062. doi: 10.1371/journal.pone.0023062. Epub 2011 Jul 29.


αB-crystallin is elevated in highly infiltrative apoptosis-resistant glioblastoma cells.

Goplen D, Bougnaud S, Rajcevic U, Bøe SO, Skaftnesmo KO, Voges J, Enger PØ, Wang J, Tysnes BB, Laerum OD, Niclou S, Bjerkvig R.

Am J Pathol. 2010 Oct;177(4):1618-28. doi: 10.2353/ajpath.2010.090063. Epub 2010 Sep 2.


Glioma cell populations grouped by different cell type markers drive brain tumor growth.

Prestegarden L, Svendsen A, Wang J, Sleire L, Skaftnesmo KO, Bjerkvig R, Yan T, Askland L, Persson A, Sakariassen PØ, Enger PØ.

Cancer Res. 2010 Jun 1;70(11):4274-9. doi: 10.1158/0008-5472.CAN-09-3904. Epub 2010 May 11.


Differential regulation of mature and precursor microRNA expression by NMDA and metabotropic glutamate receptor activation during LTP in the adult dentate gyrus in vivo.

Wibrand K, Panja D, Tiron A, Ofte ML, Skaftnesmo KO, Lee CS, Pena JT, Tuschl T, Bramham CR.

Eur J Neurosci. 2010 Feb;31(4):636-45. doi: 10.1111/j.1460-9568.2010.07112.x.


Remission of invasive, cancer stem-like glioblastoma xenografts using lentiviral vector-mediated suicide gene therapy.

Huszthy PC, Giroglou T, Tsinkalovsky O, Euskirchen P, Skaftnesmo KO, Bjerkvig R, von Laer D, Miletic H.

PLoS One. 2009 Jul 20;4(7):e6314. doi: 10.1371/journal.pone.0006314.


Highly infiltrative brain tumours show reduced chemosensitivity associated with a stem cell-like phenotype.

Johannessen TC, Wang J, Skaftnesmo KO, Sakariassen PØ, Enger PØ, Petersen K, Øyan AM, Kalland KH, Bjerkvig R, Tysnes BB.

Neuropathol Appl Neurobiol. 2009 Aug;35(4):380-93. doi: 10.1111/j.1365-2990.2008.01008.x.


MicroRNAs in tumorigenesis.

Skaftnesmo KO, Prestegarden L, Micklem DR, Lorens JB.

Curr Pharm Biotechnol. 2007 Dec;8(6):320-5. Review.


Angiogenesis-independent tumor growth mediated by stem-like cancer cells.

Sakariassen PØ, Prestegarden L, Wang J, Skaftnesmo KO, Mahesparan R, Molthoff C, Sminia P, Sundlisaeter E, Misra A, Tysnes BB, Chekenya M, Peters H, Lende G, Kalland KH, Øyan AM, Petersen K, Jonassen I, van der Kogel A, Feuerstein BG, Terzis AJ, Bjerkvig R, Enger PØ.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16466-71. Epub 2006 Oct 20.


Primary glioma spheroids maintain tumourogenicity and essential phenotypic traits after cryopreservation.

Sundlisaeter E, Wang J, Sakariassen PØ, Marie M, Mathisen JR, Karlsen BO, Prestegarden L, Skaftnesmo KO, Bjerkvig R, Enger PØ.

Neuropathol Appl Neurobiol. 2006 Aug;32(4):419-27.


Antitumor efficacy improved by local delivery of species-specific endostatin.

Huszthy PC, Brekken C, Pedersen TB, Thorsen F, Sakariassen PO, Skaftnesmo KO, Haraldseth O, Lønning PE, Bjerkvig R, Enger PO.

J Neurosurg. 2006 Jan;104(1):118-28.


Distribution patterns of the anti-angiogenic protein ADAMTS-1 during rat development.

Günther W, Skaftnesmo KO, Arnold H, Bjerkvig R, Terzis AJ.

Acta Histochem. 2005;107(2):121-31.


Molecular approaches to brain tumour invasion.

Günther W, Skaftnesmo KO, Arnold H, Terzis AJ.

Acta Neurochir (Wien). 2003 Dec;145(12):1029-36. Epub 2003 Aug 22. Review.


Expression of extracellular matrix components in a highly infiltrative in vivo glioma model.

Mahesparan R, Read TA, Lund-Johansen M, Skaftnesmo KO, Bjerkvig R, Engebraaten O.

Acta Neuropathol. 2003 Jan;105(1):49-57. Epub 2002 Nov 1.


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