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Items: 1 to 50 of 61

1.

Galactosylated PLGA nanoparticles for the oral delivery of resveratrol: enhanced bioavailability and in vitro anti-inflammatory activity.

Siu FY, Ye S, Lin H, Li S.

Int J Nanomedicine. 2018 Jul 13;13:4133-4144. doi: 10.2147/IJN.S164235. eCollection 2018.

2.

Effect of astragaloside IV on diabetic gastric mucosa in vivo and in vitro.

Wang N, Siu F, Zhang Y.

Am J Transl Res. 2017 Nov 15;9(11):4902-4913. eCollection 2017.

3.

Relationship Between Nutritional Factors and Hip Bone Density in Individuals with Chronic Stroke.

Li SKY, Wan MMP, Siu FPL, Chung S, Pang MYC.

Calcif Tissue Int. 2017 Sep;101(3):259-270. doi: 10.1007/s00223-017-0276-1. Epub 2017 Apr 17.

PMID:
28417148
4.

Activatable albumin-photosensitizer nanoassemblies for triple-modal imaging and thermal-modulated photodynamic therapy of cancer.

Hu D, Sheng Z, Gao G, Siu F, Liu C, Wan Q, Gong P, Zheng H, Ma Y, Cai L.

Biomaterials. 2016 Jul;93:10-19. doi: 10.1016/j.biomaterials.2016.03.037. Epub 2016 Mar 31.

PMID:
27061266
5.

Self-Monitoring Artificial Red Cells with Sufficient Oxygen Supply for Enhanced Photodynamic Therapy.

Luo Z, Zheng M, Zhao P, Chen Z, Siu F, Gong P, Gao G, Sheng Z, Zheng C, Ma Y, Cai L.

Sci Rep. 2016 Mar 18;6:23393. doi: 10.1038/srep23393.

6.

Conformational states of the full-length glucagon receptor.

Yang L, Yang D, de Graaf C, Moeller A, West GM, Dharmarajan V, Wang C, Siu FY, Song G, Reedtz-Runge S, Pascal BD, Wu B, Potter CS, Zhou H, Griffin PR, Carragher B, Yang H, Wang MW, Stevens RC, Jiang H.

Nat Commun. 2015 Jul 31;6:7859. doi: 10.1038/ncomms8859.

7.

Isothermal chemical denaturation to determine binding affinity of small molecules to G-protein coupled receptors.

Ross P, Weihofen W, Siu F, Xie A, Katakia H, Wright SK, Hunt I, Brown RK, Freire E.

Anal Biochem. 2015 Mar 15;473:41-5. doi: 10.1016/j.ab.2014.11.019. Epub 2014 Dec 4.

8.

Mechanisms underlying the effect of acupuncture on cognitive improvement: a systematic review of animal studies.

Leung MC, Yip KK, Ho YS, Siu FK, Li WC, Garner B.

J Neuroimmune Pharmacol. 2014 Sep;9(4):492-507. doi: 10.1007/s11481-014-9550-4. Epub 2014 Jun 6. Review.

PMID:
24903518
9.

Anatomical transcriptome of G protein-coupled receptors leads to the identification of a novel therapeutic candidate GPR52 for psychiatric disorders.

Komatsu H, Maruyama M, Yao S, Shinohara T, Sakuma K, Imaichi S, Chikatsu T, Kuniyeda K, Siu FK, Peng LS, Zhuo K, Mun LS, Han TM, Matsumoto Y, Hashimoto T, Miyajima N, Itoh Y, Ogi K, Habata Y, Mori M.

PLoS One. 2014 Feb 28;9(2):e90134. doi: 10.1371/journal.pone.0090134. eCollection 2014.

10.

Genetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCR.

Coin I, Katritch V, Sun T, Xiang Z, Siu FY, Beyermann M, Stevens RC, Wang L.

Cell. 2013 Dec 5;155(6):1258-69. doi: 10.1016/j.cell.2013.11.008. Epub 2013 Nov 27.

11.

Sequence selectivity of the cleavage sites induced by topoisomerase I inhibitors: a molecular dynamics study.

Siu FM, Pommier Y.

Nucleic Acids Res. 2013 Dec;41(22):10010-9. doi: 10.1093/nar/gkt791. Epub 2013 Sep 9.

12.

A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma.

Wang N, Feng Y, Zhu M, Siu FM, Ng KM, Che CM.

Biochim Biophys Acta. 2013 Dec;1833(12):2890-2899. doi: 10.1016/j.bbamcr.2013.07.018. Epub 2013 Jul 29.

13.

Structure of the human glucagon class B G-protein-coupled receptor.

Siu FY, He M, de Graaf C, Han GW, Yang D, Zhang Z, Zhou C, Xu Q, Wacker D, Joseph JS, Liu W, Lau J, Cherezov V, Katritch V, Wang MW, Stevens RC.

Nature. 2013 Jul 25;499(7459):444-9. doi: 10.1038/nature12393. Epub 2013 Jul 17.

14.

Engineered nanostructured β-sheet peptides protect membrane proteins.

Tao H, Lee SC, Moeller A, Roy RS, Siu FY, Zimmermann J, Stevens RC, Potter CS, Carragher B, Zhang Q.

Nat Methods. 2013 Aug;10(8):759-61. doi: 10.1038/nmeth.2533. Epub 2013 Jun 30.

15.

Selective overexpression of human SIRT1 in adipose tissue enhances energy homeostasis and prevents the deterioration of insulin sensitivity with ageing in mice.

Xu C, Bai B, Fan P, Cai Y, Huang B, Law IK, Liu L, Xu A, Tung C, Li X, Siu FM, Che CM, Vanhoutte PM, Wang Y.

Am J Transl Res. 2013 May 24;5(4):412-26. Print 2013.

16.

Structure of the human smoothened receptor bound to an antitumour agent.

Wang C, Wu H, Katritch V, Han GW, Huang XP, Liu W, Siu FY, Roth BL, Cherezov V, Stevens RC.

Nature. 2013 May 16;497(7449):338-43. doi: 10.1038/nature12167. Epub 2013 May 1.

17.

Structural features for functional selectivity at serotonin receptors.

Wacker D, Wang C, Katritch V, Han GW, Huang XP, Vardy E, McCorvy JD, Jiang Y, Chu M, Siu FY, Liu W, Xu HE, Cherezov V, Roth BL, Stevens RC.

Science. 2013 May 3;340(6132):615-9. doi: 10.1126/science.1232808. Epub 2013 Mar 21.

18.

Diastereoselective ruthenium porphyrin-catalyzed tandem nitrone formation/1,3-dipolar cycloaddition for isoxazolidines. Synthesis, in silico docking study and in vitro biological activities.

Reddy AR, Guo Z, Siu FM, Lok CN, Liu F, Yeung KC, Zhou CY, Che CM.

Org Biomol Chem. 2012 Dec 14;10(46):9165-74. doi: 10.1039/c2ob26518d. Epub 2012 Sep 11.

PMID:
22964756
19.

Highly regio-, diastereo- and enantioselective one-pot gold/chiral Brønsted acid-catalysed cascade synthesis of bioactive diversely substituted tetrahydroquinolines.

Liu XY, Xiao YP, Siu FM, Ni LC, Chen Y, Wang L, Che CM.

Org Biomol Chem. 2012 Sep 21;10(35):7208-19. doi: 10.1039/c2ob25753j. Epub 2012 Jul 11.

PMID:
22785458
20.
21.

Comparison of the interface pressure and stiffness of four types of compression systems.

Wong IK, Man MB, Chan OS, Siu FC, Abel M, Andriessen A.

J Wound Care. 2012 Apr;21(4):161, 164, 166-7.

PMID:
22584673
22.

Antibiotic-resistant Propionibacterium acnes among acne patients in a regional skin centre in Hong Kong.

Luk NM, Hui M, Lee HC, Fu LH, Liu ZH, Lam LY, Eastel M, Chan YK, Tang LS, Cheng TS, Siu FY, Ng SC, Lai YK, Ho KM.

J Eur Acad Dermatol Venereol. 2013 Jan;27(1):31-6. doi: 10.1111/j.1468-3083.2011.04351.x. Epub 2011 Nov 21.

PMID:
22103749
23.

Anticancer gold(I)-phosphine complexes as potent autophagy-inducing agents.

Tian S, Siu FM, Kui SC, Lok CN, Che CM.

Chem Commun (Camb). 2011 Sep 7;47(33):9318-20. doi: 10.1039/c1cc11820j. Epub 2011 May 16.

PMID:
21584293
24.

Methionine aminopeptidase as a novel target for antibiotic therapy against Staphylococcus aureus: a proteomic approach.

Kao RY, Yuen KY, Che CM, Siu FM.

Hong Kong Med J. 2011 Feb;17 Suppl 2:29-31. No abstract available.

25.

RAMP-ing up class-B GPCR ECD structural coverage.

Siu FY, Stevens RC.

Structure. 2010 Sep 8;18(9):1067-8. doi: 10.1016/j.str.2010.08.004. No abstract available.

26.

An indispensable role of secretin in mediating the osmoregulatory functions of angiotensin II.

Lee VH, Lee LT, Chu JY, Lam IP, Siu FK, Vaudry H, Chow BK.

FASEB J. 2010 Dec;24(12):5024-32. doi: 10.1096/fj.10-165399. Epub 2010 Aug 25.

27.

Metal complexes in medicine with a focus on enzyme inhibition.

Che CM, Siu FM.

Curr Opin Chem Biol. 2010 Apr;14(2):255-61. doi: 10.1016/j.cbpa.2009.11.015. Epub 2009 Dec 16. Review.

PMID:
20018553
28.

Persistence of camptothecin analog-topoisomerase I-DNA ternary complexes: a molecular dynamics study.

Siu FM, Che CM.

J Am Chem Soc. 2008 Dec 31;130(52):17928-37. doi: 10.1021/ja806934y.

PMID:
19035632
29.

Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways.

Siu FM, Ma DL, Cheung YW, Lok CN, Yan K, Yang Z, Yang M, Xu S, Ko BC, He QY, Che CM.

Proteomics. 2008 Aug;8(15):3105-17. doi: 10.1002/pmic.200700829.

PMID:
18615425
30.

Fluorophore-labeled beta-lactamase as a biosensor for beta-lactam antibiotics: a study of the biosensing process.

Chan PH, So PK, Ma DL, Zhao Y, Lai TS, Chung WH, Chan KC, Yiu KF, Chan HW, Siu FM, Tsang CW, Leung YC, Wong KY.

J Am Chem Soc. 2008 May 21;130(20):6351-61. doi: 10.1021/ja076111g. Epub 2008 Apr 23.

PMID:
18429614
31.

Multiple actions of secretin in the human body.

Lam IP, Siu FK, Chu JY, Chow BK.

Int Rev Cytol. 2008;265:159-90. doi: 10.1016/S0074-7696(07)65004-9. Review.

PMID:
18275888
32.

Southwestern blotting in investigating transcriptional regulation.

Siu FK, Lee LT, Chow BK.

Nat Protoc. 2008;3(1):51-8. doi: 10.1038/nprot.2007.492.

PMID:
18193021
33.

A neuroprotective herbal mixture inhibits caspase-3-independent apoptosis in retinal ganglion cells.

Cheung ZH, Leung MC, Yip HK, Wu W, Siu FK, So KF.

Cell Mol Neurobiol. 2008 Jan;28(1):137-55. Epub 2007 Aug 21.

PMID:
17710535
34.

Discovery of growth hormone-releasing hormones and receptors in nonmammalian vertebrates.

Lee LT, Siu FK, Tam JK, Lau IT, Wong AO, Lin MC, Vaudry H, Chow BK.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2133-8. Epub 2007 Feb 5.

35.
36.
37.
38.

Signaling mechanisms of secretin receptor.

Siu FK, Lam IP, Chu JY, Chow BK.

Regul Pept. 2006 Nov 15;137(1-2):95-104. Epub 2006 Aug 22. Review.

PMID:
16930743
39.

The prenatal expression of secretin receptor.

Siu FK, Sham MH, Chow BK.

Ann N Y Acad Sci. 2006 Jul;1070:561-5.

PMID:
16888225
40.

RNA-mediated interaction between the peptide-binding and GTPase domains of the signal recognition particle.

Spanggord RJ, Siu F, Ke A, Doudna JA.

Nat Struct Mol Biol. 2005 Dec;12(12):1116-22. Epub 2005 Nov 20.

PMID:
16299512
42.

Secretin, a known gastrointestinal peptide, is widely expressed during mouse embryonic development.

Siu FK, Sham MH, Chow BK.

Gene Expr Patterns. 2005 Feb;5(3):445-51.

PMID:
15661652
45.

Regulation of caspase activation in axotomized retinal ganglion cells.

Cheung ZH, Chan YM, Siu FK, Yip HK, Wu W, Leung MC, So KF.

Mol Cell Neurosci. 2004 Mar;25(3):383-93.

PMID:
15033167
46.
49.

Absolute potassium cation affinities (PCAs) in the gas phase.

Lau JK, Wong CH, Ng PS, Siu FM, Ma NL, Tsang CW.

Chemistry. 2003 Jul 21;9(14):3383-96.

PMID:
12866082
50.

Total retinal nitric oxide production is increased in intraocular pressure-elevated rats.

Siu AW, Leung MC, To CH, Siu FK, Ji JZ, So KF.

Exp Eye Res. 2002 Oct;75(4):401-6.

PMID:
12387787

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