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Items: 1 to 50 of 1102

1.

Identification of variants in pleiotropic genes causing "isolated" premature ovarian insufficiency: implications for medical practice.

Tucker EJ, Grover SR, Robevska G, van den Bergen J, Hanna C, Sinclair AH.

Eur J Hum Genet. 2018 Apr 30. doi: 10.1038/s41431-018-0140-4. [Epub ahead of print]

PMID:
29706645
2.

Arachidonic acid supplementation transiently augments the acute inflammatory response to resistance exercise in trained men.

Markworth JF, D'Souza RF, Aasen KMM, Mitchell SM, Durainayagam BR, Sinclair AJ, Peake JM, Egner IM, Raastad T, Cameron-Smith D, Mitchell CJ.

J Appl Physiol (1985). 2018 Apr 26. doi: 10.1152/japplphysiol.00169.2018. [Epub ahead of print]

PMID:
29698111
3.

Mean HbA1c, HbA1c variability, and mortality in people with diabetes aged 70 years and older: a retrospective cohort study.

Forbes A, Murrells T, Mulnier H, Sinclair AJ.

Lancet Diabetes Endocrinol. 2018 Apr 16. pii: S2213-8587(18)30048-2. doi: 10.1016/S2213-8587(18)30048-2. [Epub ahead of print]

PMID:
29674135
4.

GATA4 Variants in Individuals With a 46,XY Disorder of Sex Development (DSD) May or May Not Be Associated With Cardiac Defects Depending on Second Hits in Other DSD Genes.

Martinez de LaPiscina I, de Mingo C, Riedl S, Rodriguez A, Pandey AV, Fernández-Cancio M, Camats N, Sinclair A, Castaño L, Audi L, Flück CE.

Front Endocrinol (Lausanne). 2018 Apr 4;9:142. doi: 10.3389/fendo.2018.00142. eCollection 2018.

5.

Trigeminal autonomic cephalgia: A rare cause of headache in children.

Stringer JA, Calvert S, Sinclair A.

J Paediatr Child Health. 2018 Apr 14. doi: 10.1111/jpc.13927. [Epub ahead of print] No abstract available.

PMID:
29655264
6.

Type 2 diabetes mellitus in older people: a brief statement of key principles of modern day management including the assessment of frailty. A national collaborative stakeholder initiative.

Strain WD, Hope SV, Green A, Kar P, Valabhji J, Sinclair AJ.

Diabet Med. 2018 Apr 7. doi: 10.1111/dme.13644. [Epub ahead of print] Review.

PMID:
29633351
7.

Diabetes Mellitus and Cognitive Decline - Prevention Should Not Be Delayed!

Sinclair AJ, Vellas B.

J Prev Alzheimers Dis. 2018;5(2):95-97. doi: 10.14283/jpad.2018.9. No abstract available.

PMID:
29616701
8.

Mechanism of activation of the BNLF2a immune evasion gene of Epstein-Barr virus by Zta.

Almohammed R, Osborn K, Ramasubramanyan S, Perez-Fernandez IBN, Godfrey A, Mancini EJ, Sinclair AJ.

J Gen Virol. 2018 Mar 26. doi: 10.1099/jgv.0.001056. [Epub ahead of print]

PMID:
29580369
9.

Evaluating the Fat Distribution in Idiopathic Intracranial Hypertension Using Dual-Energy X-ray Absorptiometry Scanning.

Hornby C, Botfield H, O'Reilly MW, Westgate C, Mitchell J, Mollan SP, Manolopoulos K, Tomlinson J, Sinclair A.

Neuroophthalmology. 2017 Jun 20;42(2):99-104. doi: 10.1080/01658107.2017.1334218. eCollection 2018 Apr.

10.

A novel, homozygous mutation in desert hedgehog (DHH) in a 46, XY patient with dysgenetic testes presenting with primary amenorrhoea: a case report.

Rothacker KM, Ayers KL, Tang D, Joshi K, van den Bergen JA, Robevska G, Samnakay N, Nagarajan L, Francis K, Sinclair AH, Choong CS.

Int J Pediatr Endocrinol. 2018;2018:2. doi: 10.1186/s13633-018-0056-3. Epub 2018 Mar 2.

11.

No effect of saturated fatty acid chain length on meal-induced thermogenesis in overweight men.

Nguo K, Huggins CE, Truby H, Sinclair AJ, Clarke RE, Bonham MP.

Nutr Res. 2018 Mar;51:102-110. doi: 10.1016/j.nutres.2018.01.003. Epub 2018 Feb 2.

PMID:
29499972
12.

How does high DHA fish oil affect health? A systematic review of evidence.

Ghasemi Fard S, Wang F, Sinclair AJ, Elliott G, Turchini GM.

Crit Rev Food Sci Nutr. 2018 Mar 1:1-44. doi: 10.1080/10408398.2018.1425978. [Epub ahead of print]

PMID:
29494205
13.

Chronic helminth infection burden differentially affects haematopoietic cell development while ageing selectively impairs adaptive responses to infection.

Babayan SA, Sinclair A, Duprez JS, Selman C.

Sci Rep. 2018 Feb 28;8(1):3802. doi: 10.1038/s41598-018-22083-5.

14.

Zwitterionic Nanocages Overcome the Efficacy Loss of Biologic Drugs.

Li B, Yuan Z, Zhang P, Sinclair A, Jain P, Wu K, Tsao C, Xie J, Hung HC, Lin X, Bai T, Jiang S.

Adv Mater. 2018 Apr;30(14):e1705728. doi: 10.1002/adma.201705728. Epub 2018 Feb 19.

PMID:
29457278
15.

hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival.

Pellicano F, Park L, Hopcroft LEM, Shah MM, Jackson L, Scott MT, Clarke CJ, Sinclair A, Abraham SA, Hair A, Helgason GV, Aspinall-O'Dea M, Bhatia R, Leone G, Kranc KR, Whetton AD, Holyoake TL.

Blood. 2018 Apr 5;131(14):1532-1544. doi: 10.1182/blood-2017-05-783845. Epub 2018 Feb 5.

PMID:
29437554
16.

Arachidonic acid supplementation modulates blood and skeletal muscle lipid profile with no effect on basal inflammation in resistance exercise trained men.

Markworth JF, Mitchell CJ, D'Souza RF, Aasen KMM, Durainayagam BR, Mitchell SM, Chan AHC, Sinclair AJ, Garg M, Cameron-Smith D.

Prostaglandins Leukot Essent Fatty Acids. 2018 Jan;128:74-86. doi: 10.1016/j.plefa.2017.12.003. Epub 2017 Dec 11.

PMID:
29413364
17.

An International Position Statement on the Management of Frailty in Diabetes Mellitus: Summary of Recommendations 2017.

Sinclair AJ, Abdelhafiz A, Dunning T, Izquierdo M, Rodriguez Manas L, Bourdel-Marchasson I, Morley JE, Munshi M, Woo J, Vellas B.

J Frailty Aging. 2018;7(1):10-20. doi: 10.14283/jfa.2017.39. Review.

PMID:
29412437
18.

Implications of ICD-10 for Sarcopenia Clinical Practice and Clinical Trials: Report by the International Conference on Frailty and Sarcopenia Research Task Force.

Vellas B, Fielding RA, Bens C, Bernabei R, Cawthon PM, Cederholm T, Cruz-Jentoft AJ, Del Signore S, Donahue S, Morley J, Pahor M, Reginster JY, Rodriguez Mañas L, Rolland Y, Roubenoff R, Sinclair A, Cesari M.

J Frailty Aging. 2018;7(1):2-9. doi: 10.14283/jfa.2017.30.

PMID:
29412436
19.

Effect of dietary arachidonic acid supplementation on acute muscle adaptive responses to resistance exercise in trained men: a randomized controlled trial.

Mitchell CJ, D'Souza RF, Figueiredo VC, Chan A, Aasen K, Durainayagam B, Mitchell S, Sinclair AJ, Egner IM, Raastad T, Cameron-Smith D, Markworth JF.

J Appl Physiol (1985). 2018 Apr 1;124(4):1080-1091. doi: 10.1152/japplphysiol.01100.2017. Epub 2018 Feb 1.

PMID:
29389245
20.

The cell biology and molecular genetics of Müllerian duct development.

Roly ZY, Backhouse B, Cutting A, Tan TY, Sinclair AH, Ayers KL, Major AT, Smith CA.

Wiley Interdiscip Rev Dev Biol. 2018 May;7(3):e310. doi: 10.1002/wdev.310. Epub 2018 Jan 19. Review.

PMID:
29350886
21.

Segmentation error in spectral domain optical coherence tomography measures of the retinal nerve fibre layer thickness in idiopathic intracranial hypertension.

Aojula A, Mollan SP, Horsburgh J, Yiangou A, Markey KA, Mitchell JL, Scotton WJ, Keane PA, Sinclair AJ.

BMC Ophthalmol. 2018 Jan 4;17(1):257. doi: 10.1186/s12886-017-0652-7.

22.

Deintensification of hypoglycaemic medications-use of a systematic review approach to highlight safety concerns in older people with type 2 diabetes.

Abdelhafiz AH, Sinclair AJ.

J Diabetes Complications. 2018 Apr;32(4):444-450. doi: 10.1016/j.jdiacomp.2017.11.011. Epub 2017 Nov 29. Review.

PMID:
29274807
23.

What Do Transgender Patients Teach Us About Idiopathic Intracranial Hypertension?

Hornby C, Mollan SP, Mitchell J, Markey KA, Yangou A, Wright BLC, O'Reilly MW, Sinclair AJ.

Neuroophthalmology. 2017 May 10;41(6):326-329. doi: 10.1080/01658107.2017.1316744. eCollection 2017.

24.

Managing diabetes in people with dementia: a realist review.

Bunn F, Goodman C, Jones PR, Russell B, Trivedi D, Sinclair A, Bayer A, Rait G, Rycroft-Malone J, Burton C.

Health Technol Assess. 2017 Dec;21(75):1-140. doi: 10.3310/hta21750.

25.
26.

36 Frailty flying squad: an emergency department focussed acute care of the elderly service DR genevieve robson, royal united hospital NHS foundation trust.

Ballham S, Buxton S, Camacho R, Sinclair A, Dyer C, Jakeman N.

Emerg Med J. 2017 Dec;34(12):A885-A886. doi: 10.1136/emermed-2017-207308.36.

PMID:
29170333
27.

Chronic Psychological Stress Was Not Ameliorated by Omega-3 Eicosapentaenoic Acid (EPA).

Bradbury J, Myers SP, Meyer B, Brooks L, Peake J, Sinclair AJ, Stough C.

Front Pharmacol. 2017 Oct 31;8:551. doi: 10.3389/fphar.2017.00551. eCollection 2017.

28.

The Role of Copy Number Variants in Disorders of Sex Development.

Croft B, Ohnesorg T, Sinclair AH.

Sex Dev. 2018;12(1-3):19-29. doi: 10.1159/000481896. Epub 2017 Nov 17.

PMID:
29145200
29.

Diverticular Disease of the Gastrointestinal Tract.

Sinclair A.

Prim Care. 2017 Dec;44(4):643-654. doi: 10.1016/j.pop.2017.07.007. Review.

PMID:
29132526
30.

Differential effects of EPA, DPA and DHA on cardio-metabolic risk factors in high-fat diet fed mice.

Guo XF, Sinclair AJ, Kaur G, Li D.

Prostaglandins Leukot Essent Fatty Acids. 2017 Sep 22. pii: S0952-3278(17)30120-5. doi: 10.1016/j.plefa.2017.09.011. [Epub ahead of print]

PMID:
29113747
31.

Continuous-relief diffractive microlenses for laser beam focusing.

Day M, Choonee K, Cox D, Thompson M, Marshall G, Sinclair AG.

Opt Express. 2017 Oct 30;25(22):26987-26999. doi: 10.1364/OE.25.026987.

PMID:
29092180
32.

XX Disorder of Sex Development is associated with an insertion on chromosome 9 and downregulation of RSPO1 in dogs (Canis lupus familiaris).

Meyers-Wallen VN, Boyko AR, Danko CG, Grenier JK, Mezey JG, Hayward JJ, Shannon LM, Gao C, Shafquat A, Rice EJ, Pujar S, Eggers S, Ohnesorg T, Sinclair AH.

PLoS One. 2017 Oct 20;12(10):e0186331. doi: 10.1371/journal.pone.0186331. eCollection 2017.

33.

Furan fatty acids - Beneficial or harmful to health?

Xu L, Sinclair AJ, Faiza M, Li D, Han X, Yin H, Wang Y.

Prog Lipid Res. 2017 Oct;68:119-137. doi: 10.1016/j.plipres.2017.10.002. Epub 2017 Oct 16. Review.

PMID:
29051014
34.

Renal Subcapsular xenografing of human fetal external genital tissue - A new model for investigating urethral development.

Isaacson D, Shen J, Cao M, Sinclair A, Yue X, Cunha G, Baskin L.

Differentiation. 2017 Nov - Dec;98:1-13. doi: 10.1016/j.diff.2017.09.002. Epub 2017 Sep 22.

PMID:
29031189
35.

Functional characterization of novel NR5A1 variants reveals multiple complex roles in disorders of sex development.

Robevska G, van den Bergen JA, Ohnesorg T, Eggers S, Hanna C, Hersmus R, Thompson EM, Baxendale A, Verge CF, Lafferty AR, Marzuki NS, Santosa A, Listyasari NA, Riedl S, Warne G, Looijenga L, Faradz S, Ayers KL, Sinclair AH.

Hum Mutat. 2018 Jan;39(1):124-139. doi: 10.1002/humu.23354. Epub 2017 Nov 2.

36.

Randomised controlled trial of bariatric surgery versus a community weight loss programme for the sustained treatment of idiopathic intracranial hypertension: the Idiopathic Intracranial Hypertension Weight Trial (IIH:WT) protocol.

Ottridge R, Mollan SP, Botfield H, Frew E, Ives NJ, Matthews T, Mitchell J, Rick C, Singhal R, Woolley R, Sinclair AJ.

BMJ Open. 2017 Sep 27;7(9):e017426. doi: 10.1136/bmjopen-2017-017426.

37.
38.

Disability from posttraumatic headache is compounded by coexisting posttraumatic stress disorder.

Roper LS, Nightingale P, Su Z, Mitchell JL, Belli A, Sinclair AJ.

J Pain Res. 2017 Aug 21;10:1991-1996. doi: 10.2147/JPR.S129808. eCollection 2017.

39.

A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus.

Botfield HF, Uldall MS, Westgate CSJ, Mitchell JL, Hagen SM, Gonzalez AM, Hodson DJ, Jensen RH, Sinclair AJ.

Sci Transl Med. 2017 Aug 23;9(404). pii: eaan0972. doi: 10.1126/scitranslmed.aan0972.

PMID:
28835515
40.

What works for whom in the management of diabetes in people living with dementia: a realist review.

Bunn F, Goodman C, Reece Jones P, Russell B, Trivedi D, Sinclair A, Bayer A, Rait G, Rycroft-Malone J, Burton C.

BMC Med. 2017 Jul 28;15(1):141. doi: 10.1186/s12916-017-0909-2. Review.

41.

Glycaemic outcomes of an Individualized treatMent aPproach for oldER vulnerable patIents: A randomized, controlled stUdy in type 2 diabetes Mellitus (IMPERIUM).

Heller SR, Pratley RE, Sinclair A, Festa A, Kiljański J, Brusko CS, Duan R, Heine RJ.

Diabetes Obes Metab. 2018 Jan;20(1):148-156. doi: 10.1111/dom.13051. Epub 2017 Aug 8.

42.

Corrigendum: Corrigendum for: Disorders of sex development: The evolving role of genomics in diagnosis and gene discovery, 108:337-350 (10.1002/bdrc.21148).

Croft B, Ayers K, Sinclair A, Ohnesorg T.

Birth Defects Res. 2017 Jul 3;109(11):869-871. doi: 10.1002/bdr2.1056. Epub 2017 Jun 12. No abstract available.

PMID:
28670874
43.

Frailty and sarcopenia - newly emerging and high impact complications of diabetes.

Sinclair AJ, Abdelhafiz AH, Rodríguez-Mañas L.

J Diabetes Complications. 2017 Sep;31(9):1465-1473. doi: 10.1016/j.jdiacomp.2017.05.003. Epub 2017 May 12. Review.

PMID:
28669464
44.

Synthetic scale-up of a novel fluorescent probe and its biological evaluation for surface detection of Staphylococcus aureus.

Bywaters L, Mulcahy-Ryan L, Fielder M, Sinclair A, Le Gresley A.

Mol Cell Probes. 2017 Dec;36:1-9. doi: 10.1016/j.mcp.2017.06.006. Epub 2017 Jun 28.

PMID:
28668278
45.

Future enhanced clinical role of pharmacists in Emergency Departments in England: multi-site observational evaluation.

Hughes E, Terry D, Huynh C, Petridis K, Aiello M, Mazard L, Ubhi H, Terry A, Wilson K, Sinclair A.

Int J Clin Pharm. 2017 Aug;39(4):960-968. doi: 10.1007/s11096-017-0497-4. Epub 2017 Jun 26.

46.

Stable and Functionalizable Quantum Dots with a Thin Zwitterionic Carboxybetaine Layer.

Yang W, Ella-Menye JR, Bai T, Sinclair A, Jiang S.

Langmuir. 2017 Sep 5;33(35):8784-8789. doi: 10.1021/acs.langmuir.7b00981. Epub 2017 Jul 10.

PMID:
28648077
47.

A Coating-Free Nonfouling Polymeric Elastomer.

Hung HC, Jain P, Zhang P, Sun F, Sinclair A, Bai T, Li B, Wu K, Tsao C, Liu EJ, Sundaram HS, Lin X, Farahani P, Fujihara T, Jiang S.

Adv Mater. 2017 Aug;29(31). doi: 10.1002/adma.201700617. Epub 2017 Jun 16.

PMID:
28620970
48.

Painful ovulation in a 46,XX SRY -ve adult male with SOX9 duplication.

Shankara Narayana N, Kean AM, Ewans L, Ohnesorg T, Ayers KL, Watson G, Vasilaras A, Sinclair AH, Twigg SM, Handelsman DJ.

Endocrinol Diabetes Metab Case Rep. 2017 Jun 7;2017. pii: 17-0045. doi: 10.1530/EDM-17-0045. eCollection 2017.

50.

Evaluating the accuracy and economic value of a new test in the absence of a perfect reference test.

Xie X, Sinclair A, Dendukuri N.

Res Synth Methods. 2017 Sep;8(3):321-332. doi: 10.1002/jrsm.1243. Epub 2017 May 23.

PMID:
28544646

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