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Items: 29

1.

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival.

Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R.

Cancer Cell. 2015 Dec 14;28(6):831-833. doi: 10.1016/j.ccell.2015.11.002. Epub 2015 Dec 14. No abstract available.

2.

Cytotoxic T lymphocyte antigen-4 blockade enhances antitumor immunity by stimulating melanoma-specific T-cell motility.

Pentcheva-Hoang T, Simpson TR, Montalvo-Ortiz W, Allison JP.

Cancer Immunol Res. 2014 Oct;2(10):970-80. doi: 10.1158/2326-6066.CIR-14-0104. Epub 2014 Jul 18.

3.

Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.

Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R.

Cancer Cell. 2014 Jun 16;25(6):719-34. doi: 10.1016/j.ccr.2014.04.005. Epub 2014 May 22. Erratum in: Cancer Cell. 2015 Dec 14;28(6):831-3.

4.

Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma.

Simpson TR, Li F, Montalvo-Ortiz W, Sepulveda MA, Bergerhoff K, Arce F, Roddie C, Henry JY, Yagita H, Wolchok JD, Peggs KS, Ravetch JV, Allison JP, Quezada SA.

J Exp Med. 2013 Aug 26;210(9):1695-710. doi: 10.1084/jem.20130579. Epub 2013 Jul 29.

5.

Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication.

Quezada SA, Peggs KS, Simpson TR, Allison JP.

Immunol Rev. 2011 May;241(1):104-18. doi: 10.1111/j.1600-065X.2011.01007.x. Review.

6.

Synthesis and SAR of sulfoxide substituted carboxyquinolines as NK3 receptor antagonists.

Xiong H, Kang J, Woods JM, McCauley JP Jr, Koether GM, Albert JS, Hinkley L, Li Y, Gadient RA, Simpson TR.

Bioorg Med Chem Lett. 2011 Mar 15;21(6):1896-9. doi: 10.1016/j.bmcl.2010.11.003. Epub 2010 Dec 21.

PMID:
21320776
7.

Assessment of biomarkers of drug-induced kidney injury in cynomolgus monkeys treated with a triple reuptake inhibitor.

Guha M, Heier A, Price S, Bielenstein M, Caccese RG, Heathcote DI, Simpson TR, Stong DB, Bodes E.

Toxicol Sci. 2011 Apr;120(2):269-83. doi: 10.1093/toxsci/kfr013. Epub 2011 Jan 22.

PMID:
21258088
8.

4-aryl piperazine and piperidine amides as novel mGluR5 positive allosteric modulators.

Xiong H, Brugel TA, Balestra M, Brown DG, Brush KA, Hightower C, Hinkley L, Hoesch V, Kang J, Koether GM, McCauley JP Jr, McLaren FM, Panko LM, Simpson TR, Smith RW, Woods JM, Brockel B, Chhajlani V, Gadient RA, Spear N, Sygowski LA, Zhang M, Arora J, Breysse N, Wilson JM, Isaac M, Slassi A, King MM.

Bioorg Med Chem Lett. 2010 Dec 15;20(24):7381-4. doi: 10.1016/j.bmcl.2010.10.036. Epub 2010 Oct 21.

PMID:
21067920
9.

In vitro assessment of metabolic drug–drug interaction potential of AZD2624, neurokinin-3 receptor antagonist, through cytochrome P(450) enzyme identification, inhibition, and induction studies.

Li Y, Zhou D, Ferguson SS, Dorff P, Simpson TR, Grimm SW.

Xenobiotica. 2010 Nov;40(11):721-9. doi: 10.3109/00498254.2010.512670.

PMID:
20937004
10.

Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts.

Quezada SA, Simpson TR, Peggs KS, Merghoub T, Vider J, Fan X, Blasberg R, Yagita H, Muranski P, Antony PA, Restifo NP, Allison JP.

J Exp Med. 2010 Mar 15;207(3):637-50. doi: 10.1084/jem.20091918. Epub 2010 Feb 15.

11.

Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS).

Simpson TR, Quezada SA, Allison JP.

Curr Opin Immunol. 2010 Jun;22(3):326-32. doi: 10.1016/j.coi.2010.01.001. Epub 2010 Jan 29. Review.

PMID:
20116985
12.

Preparing for biofilm studies in the field.

McLean RJ, Simpson TR.

Curr Protoc Microbiol. 2008 Aug;Chapter 1:Unit 1B.4.1-1B.1.14. doi: 10.1002/9780471729259.mc01b04s10.

PMID:
18729052
13.

Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma.

Quezada SA, Peggs KS, Simpson TR, Shen Y, Littman DR, Allison JP.

J Exp Med. 2008 Sep 1;205(9):2125-38. doi: 10.1084/jem.20080099. Epub 2008 Aug 25.

14.

Interspecific transmission of Brucella abortus from experimentally infected coyotes (Canis latrans) to parturient cattle.

Davis DS, Heck FC, Williams JD, Simpson TR, Adams LG.

J Wildl Dis. 1988 Jul;24(3):533-7.

PMID:
3137371
15.

Poison control revisited.

Simpson TR Jr, Simpson TR 3rd.

J Am Pharm Assoc. 1976 Dec;16(12):659-63. No abstract available.

PMID:
993551
16.

The transpubic repair of the ruptured prostato-membranous urethra and prostato-membranous urethral strictures.

Honey RM, Simpson TR.

Cent Afr J Med. 1974 Aug;20(8):169-72. No abstract available.

PMID:
4424888
17.

New rules for O-T-C advertising.

Simpson TR.

J Am Pharm Assoc. 1973 Jun;13(6):277. No abstract available.

PMID:
4710075
18.

Problems with intravenous solutions.

Gladhart WR Jr, Simpson TR 3rd.

Am J Hosp Pharm. 1972 Nov;29(11):918. No abstract available.

PMID:
4654997
19.
20.

Determination of the conformation of nicotine and some related compounds by nuclear magnetic resonance and dipole moments.

Simpson TR Jr, Craig JC, Kumler WD.

J Pharm Sci. 1967 Jun;56(6):708-13. No abstract available.

PMID:
6034803
21.

COLOCYSTOPLASTY FOR THE BILHARZIAL BLADDER.

SIMPSON TR.

Cent Afr J Med. 1965 Mar;11:53-66. No abstract available.

PMID:
14282183
22.

MPILO HOSPITAL STAFF CLINICAL MEETING. CASE NO. 18.

SIMPSON TR.

Cent Afr J Med. 1963 Sep;9:378-9. No abstract available.

PMID:
14061792
23.

MPILO HOSPITAL STAFF CLINICAL MEETING. CASE NO. 17.

SIMPSON TR.

Cent Afr J Med. 1963 Sep;9:376-7. No abstract available.

PMID:
14061791
24.

MPILO HOSPITAL STAFF CLINICAL MEETING. CASE NO. 16.

SIMPSON TR.

Cent Afr J Med. 1963 Sep;9:376. No abstract available.

PMID:
14061790
25.

MPILO HOSPITAL STAFF CLINICAL MEETING. CASE NO. 15.

SIMPSON TR.

Cent Afr J Med. 1963 Sep;9:375-6. No abstract available.

PMID:
14061789
26.

A CASE OF BILATERAL BILHARZIAL STRICTURE OF THE UPPER URETER.

SIMPSON TR.

Cent Afr J Med. 1963 Sep;9:364-7. No abstract available.

PMID:
14061788
27.

Two unsuccessful suicidal attempts with a new drug: methaminodiazepoxide (Librium).

CLARKE TP, SIMPSON TR, WISE SP 3rd.

Tex State J Med. 1961 Jan;57:24-6. No abstract available.

PMID:
13693906
28.

Spontaneous rupture of the esophagus.

BUTLER WP, SIMPSON TR.

J La State Med Soc. 1953 Feb;105(2):67-8. No abstract available.

PMID:
13023128
29.

A case of osteochondritis dissecans of the ankle.

SIMPSON TR.

Br J Surg. 1950 Jan;37(147):359. No abstract available.

PMID:
15403749

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