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Influenza news from the frontline: what's happening?

Simonds AK.

ERJ Open Res. 2018 Feb 16;4(1). pii: 00020-2018. doi: 10.1183/23120541.00020-2018. eCollection 2018 Jan.


Diagnosis and management of spinal muscular atrophy: Part 2: Pulmonary and acute care; medications, supplements and immunizations; other organ systems; and ethics.

Finkel RS, Mercuri E, Meyer OH, Simonds AK, Schroth MK, Graham RJ, Kirschner J, Iannaccone ST, Crawford TO, Woods S, Muntoni F, Wirth B, Montes J, Main M, Mazzone ES, Vitale M, Snyder B, Quijano-Roy S, Bertini E, Davis RH, Qian Y, Sejersen T; SMA Care group.

Neuromuscul Disord. 2018 Mar;28(3):197-207. doi: 10.1016/j.nmd.2017.11.004. Epub 2017 Nov 23.


Diagnosis and management of spinal muscular atrophy: Part 1: Recommendations for diagnosis, rehabilitation, orthopedic and nutritional care.

Mercuri E, Finkel RS, Muntoni F, Wirth B, Montes J, Main M, Mazzone ES, Vitale M, Snyder B, Quijano-Roy S, Bertini E, Davis RH, Meyer OH, Simonds AK, Schroth MK, Graham RJ, Kirschner J, Iannaccone ST, Crawford TO, Woods S, Qian Y, Sejersen T; SMA Care Group.

Neuromuscul Disord. 2018 Feb;28(2):103-115. doi: 10.1016/j.nmd.2017.11.005. Epub 2017 Nov 23.


Adaptive servo-ventilation for central sleep apnoea in systolic heart failure: results of the major substudy of SERVE-HF.

Cowie MR, Woehrle H, Wegscheider K, Vettorazzi E, Lezius S, Koenig W, Weidemann F, Smith G, Angermann C, d'Ortho MP, Erdmann E, Levy P, Simonds AK, Somers VK, Zannad F, Teschler H.

Eur J Heart Fail. 2017 Nov 30. doi: 10.1002/ejhf.1048. [Epub ahead of print]


The search for cardiovascular benefit from treating obstructive sleep apnoea with CPAP therapy.

Cowie MR, Gallagher AM, Simonds AK.

Eur Heart J. 2017 Nov 22. doi: 10.1093/eurheartj/ehx678. [Epub ahead of print] No abstract available.


The Epworth Sleepiness Scale: Minimum Clinically Important Difference in Obstructive Sleep Apnea.

Patel S, Kon SSC, Nolan CM, Barker RE, Simonds AK, Morrell MJ, Man WD.

Am J Respir Crit Care Med. 2017 Sep 29. doi: 10.1164/rccm.201704-0672LE. [Epub ahead of print] No abstract available.


Adaptive servo ventilation for central sleep apnoea in heart failure: SERVE-HF on-treatment analysis.

Woehrle H, Cowie MR, Eulenburg C, Suling A, Angermann C, d'Ortho MP, Erdmann E, Levy P, Simonds AK, Somers VK, Zannad F, Teschler H, Wegscheider K.

Eur Respir J. 2017 Aug 31;50(2). pii: 1601692. doi: 10.1183/13993003.01692-2016. Print 2017 Aug.


The Road Not Taken: Missed Opportunities in Managing Acute Exacerbations of Hypercapnic Respiratory Failure.

Simonds AK.

Am J Respir Crit Care Med. 2017 Jul 15;196(2):124-125. doi: 10.1164/rccm.201612-2543ED. No abstract available.


Randomized crossover trial of a pressure sensing visual feedback system to improve mask fitting in noninvasive ventilation.

Brill AK, Moghal M, Morrell MJ, Simonds AK.

Respirology. 2017 Oct;22(7):1343-1349. doi: 10.1111/resp.13074. Epub 2017 May 15.


AJRCCM: 100-Year Anniversary. Homeward Bound: A Centenary of Home Mechanical Ventilation.

Hind M, Polkey MI, Simonds AK.

Am J Respir Crit Care Med. 2017 May 1;195(9):1140-1149. doi: 10.1164/rccm.201702-0285CI. Review.


Sleepiness and activity in heart failure patients with reduced ejection fraction and central sleep-disordered breathing.

Atalla A, Carlisle TW, Simonds AK, Cowie MR, Morrell MJ.

Sleep Med. 2017 Jun;34:217-223. doi: 10.1016/j.sleep.2016.11.022. Epub 2017 Jan 23.


Continuing professional development: introducing the ERS International Certificate in Respiratory Sleep Medicine.

Mitchell S, Riha RL, Rohde G, Simonds AK.

Breathe (Sheff). 2017 Mar;13(1):11-14. doi: 10.1183/20734735.001617.


Investigation of the link between fluid shift and airway collapsibility as a mechanism for obstructive sleep apnea in congestive heart failure.

Carlisle T, Ward NR, Atalla A, Cowie MR, Simonds AK, Morrell MJ.

Physiol Rep. 2017 Jan;5(1). pii: e12956. doi: 10.14814/phy2.12956.


Mechanisms underlying increased mortality risk in patients with heart failure and reduced ejection fraction randomly assigned to adaptive servoventilation in the SERVE-HF study: results of a secondary multistate modelling analysis.

Eulenburg C, Wegscheider K, Woehrle H, Angermann C, d'Ortho MP, Erdmann E, Levy P, Simonds AK, Somers VK, Zannad F, Teschler H, Cowie MR.

Lancet Respir Med. 2016 Nov;4(11):873-881. doi: 10.1016/S2213-2600(16)30244-2. Epub 2016 Aug 31.


Practical Recommendations for Diagnosis and Management of Respiratory Muscle Weakness in Late-Onset Pompe Disease.

Boentert M, Prigent H, Várdi K, Jones HN, Mellies U, Simonds AK, Wenninger S, Barrot Cortés E, Confalonieri M.

Int J Mol Sci. 2016 Oct 17;17(10). pii: E1735. Review.


Home Mechanical Ventilation: An Overview.

Simonds AK.

Ann Am Thorac Soc. 2016 Nov;13(11):2035-2044. Review.


Progress in respiratory management of bulbar complications of motor neuron disease/amyotrophic lateral sclerosis?

Simonds AK.

Thorax. 2017 Mar;72(3):199-201. doi: 10.1136/thoraxjnl-2016-208919. Epub 2016 Aug 12. No abstract available.


DiPALS: Diaphragm Pacing in patients with Amyotrophic Lateral Sclerosis - a randomised controlled trial.

McDermott CJ, Bradburn MJ, Maguire C, Cooper CL, Baird WO, Baxter SK, Cohen J, Cantrill H, Dixon S, Ackroyd R, Baudouin S, Bentley A, Berrisford R, Bianchi S, Bourke SC, Darlison R, Ealing J, Elliott M, Fitzgerald P, Galloway S, Hamdalla H, Hanemann CO, Hughes P, Imam I, Karat D, Leek R, Maynard N, Orrell RW, Sarela A, Stradling J, Talbot K, Taylor L, Turner M, Simonds AK, Williams T, Wedzicha W, Young C, Shaw PJ.

Health Technol Assess. 2016 Jun;20(45):1-186. doi: 10.3310/hta20450.


Changes in Neurocognitive Architecture in Patients with Obstructive Sleep Apnea Treated with Continuous Positive Airway Pressure.

Rosenzweig I, Glasser M, Crum WR, Kempton MJ, Milosevic M, McMillan A, Leschziner GD, Kumari V, Goadsby P, Simonds AK, Williams SC, Morrell MJ.

EBioMedicine. 2016 May;7:221-9. doi: 10.1016/j.ebiom.2016.03.020. Epub 2016 Mar 25.


Randomised crossover trial of telemonitoring in chronic respiratory patients (TeleCRAFT trial).

Chatwin M, Hawkins G, Panicchia L, Woods A, Hanak A, Lucas R, Baker E, Ramhamdany E, Mann B, Riley J, Cowie MR, Simonds AK.

Thorax. 2016 Apr;71(4):305-11.


Adaptive Servo-Ventilation for Central Sleep Apnea in Systolic Heart Failure.

Cowie MR, Woehrle H, Wegscheider K, Angermann C, d'Ortho MP, Erdmann E, Levy P, Simonds AK, Somers VK, Zannad F, Teschler H.

N Engl J Med. 2015 Sep 17;373(12):1095-105. doi: 10.1056/NEJMoa1506459. Epub 2015 Sep 1.


ERJ Open Research: FAQs.

Simonds AK, Reeves EL.

Eur Respir J. 2015 Aug;46(2):318-20. doi: 10.1183/13993003.00904-2015. No abstract available.


Bench Comparative Assessment of Mechanically Assisted Cough Devices.

Frigerio P, Longhini F, Sommariva M, Stagni EG, Curto F, Redaelli T, Ciboldi M, Simonds AK, Navalesi P.

Respir Care. 2015 Jul;60(7):975-82. doi: 10.4187/respcare.03809. Epub 2015 May 5.


Welcome with Open arms!

Simonds AK.

ERJ Open Res. 2015 May 6;1(1). pii: 00013-2015. eCollection 2015 May.


Long term non-invasive ventilation in children: impact on survival and transition to adult care.

Chatwin M, Tan HL, Bush A, Rosenthal M, Simonds AK.

PLoS One. 2015 May 1;10(5):e0125839. doi: 10.1371/journal.pone.0125839. eCollection 2015.


"Education is the passport to the future": enabling today's medical teachers to prepare tomorrow's respiratory health practitioners.

Mitchell S, Bloch KE, Butiene I, Cooper BG, Steenbruggen I, Hare A, Kostikas K, Adcock IM, Paton J, Fletcher M, Stevenson R, Rohde G, Simonds AK.

Eur Respir J. 2014 Sep;44(3):578-84. doi: 10.1183/09031936.00109314. No abstract available.


Defining a training framework for clinicians in respiratory critical care.

Artigas A, Noël JL, Brochard L, Busari JO, Dellweg D, Ferrer M, Geiseler J, Larsson A, Nava S, Navalesi P, Orfanos S, Palange P, Pelosi P, Rohde G, Schoenhofer B, Vassilakopoulos T, Simonds AK.

Eur Respir J. 2014 Sep;44(3):572-7. doi: 10.1183/09031936.00104914. No abstract available.


Upper airway factors that protect against obstructive sleep apnoea in healthy older males.

Carlisle T, Carthy ER, Glasser M, Drivas P, McMillan A, Cowie MR, Simonds AK, Morrell MJ.

Eur Respir J. 2014 Sep;44(3):685-93. doi: 10.1183/09031936.00177213. Epub 2014 May 15.


The European Respiratory Society plans its future: the 2013-2018 strategic plan.

Migliori GB, Rabe KF, Bel E, Elliott M, Gaga M, Holgate ST, Joos G, Burrieza FM, Sax B, Sculier JP, Simonds AK, Blasi F, Barnes PJ.

Eur Respir J. 2014 Apr;43(4):927-32. doi: 10.1183/09031936.00221613. No abstract available.


Randomized trial of 'intelligent' autotitrating ventilation versus standard pressure support non-invasive ventilation: impact on adherence and physiological outcomes.

Kelly JL, Jaye J, Pickersgill RE, Chatwin M, Morrell MJ, Simonds AK.

Respirology. 2014 May;19(4):596-603. doi: 10.1111/resp.12269. Epub 2014 Mar 24.


New modalities for non-invasive ventilation.

Simonds AK, Hare A.

Clin Med (Lond). 2013 Dec;13 Suppl 6:s41-5. doi: 10.7861/clinmedicine.13-6-s41.


The effect of respiratory scoring on the diagnosis and classification of sleep disordered breathing in chronic heart failure.

Ward NR, Roldao V, Cowie MR, Rosen SD, McDonagh TA, Simonds AK, Morrell MJ.

Sleep. 2013 Sep 1;36(9):1341-8. doi: 10.5665/sleep.2960.


Chronic hypoventilation and its management.

Simonds AK.

Eur Respir Rev. 2013 Sep 1;22(129):325-32. doi: 10.1183/09059180.00003113. Review.


Risk management protocol for gastrostomy and jejunostomy insertion in ventilator dependent infants.

Chatwin M, Bush A, Macrae DJ, Clarke SA, Simonds AK.

Neuromuscul Disord. 2013 Apr;23(4):289-97. doi: 10.1016/j.nmd.2013.01.006. Epub 2013 Mar 7.


Palliating breathlessness in patients with advanced cancer.

Simonds AK.

Lancet Oncol. 2013 Mar;14(3):181-2. doi: 10.1016/S1470-2045(13)70052-4. Epub 2013 Feb 11. No abstract available.


Perspectives in medical education: signposts to the future in educating respiratory specialists.

Palange P, Busari J, Hare A, McKillop JH, Noël JL, Rosen MJ, Simonds AK, Stevenson R.

Eur Respir J. 2012 Mar;39(3):520-4. doi: 10.1183/09031936.00189211. No abstract available.


The European Respiratory Society: future directions in medical education.

Palange P, Noel JL, Simonds AK.

Eur Respir J. 2011 Sep;38(3):498-9. doi: 10.1183/09031936.00106511. No abstract available.


Sleep HERMES: a European training project for respiratory sleep medicine.

De Backer W, Simonds AK, Horn V, Andreas S, Bonsignore M, Calverley P, Donic V, Lévy P, Mitchell S, McNicholas WT, Morrell M, Randerath W, Riha RL, Trang H, Verbraecken J, Palange P.

Eur Respir J. 2011 Sep;38(3):496-7. doi: 10.1183/09031936.00095111. No abstract available.


Evaluation of droplet dispersion during non-invasive ventilation, oxygen therapy, nebuliser treatment and chest physiotherapy in clinical practice: implications for management of pandemic influenza and other airborne infections.

Simonds AK, Hanak A, Chatwin M, Morrell M, Hall A, Parker KH, Siggers JH, Dickinson RJ.

Health Technol Assess. 2010 Oct;14(46):131-172. doi: 10.3310/hta14460-02.


Respiratory management of congenital myasthenic syndromes in childhood: Workshop 8th December 2009, UCL Institute of Neurology, London, UK.

Robb SA, Muntoni F, Simonds AK.

Neuromuscul Disord. 2010 Dec;20(12):833-8. doi: 10.1016/j.nmd.2010.08.002. Epub 2010 Sep 17. No abstract available.


Outcome of goal-directed non-invasive ventilation and mechanical insufflation/exsufflation in spinal muscular atrophy type I.

Chatwin M, Bush A, Simonds AK.

Arch Dis Child. 2011 May;96(5):426-32. doi: 10.1136/adc.2009.177832. Epub 2010 Jun 23.


Obstructive sleep apnea syndrome is associated with deficits in verbal but not visual memory.

Twigg GL, Papaioannou I, Jackson M, Ghiassi R, Shaikh Z, Jaye J, Graham KS, Simonds AK, Morrell MJ.

Am J Respir Crit Care Med. 2010 Jul 1;182(1):98-103. doi: 10.1164/rccm.200901-0065OC. Epub 2010 Mar 18.


Sleep architecture and attenuated heart rate response to arousal from sleep in patients with autonomic failure.

Freilich S, Goff EA, Malaweera AS, Twigg GL, Simonds AK, Mathias CJ, Morrell MJ.

Sleep Med. 2010 Jan;11(1):87-92. doi: 10.1016/j.sleep.2008.12.017. Epub 2009 Dec 4.


Differential effects of waking from non-rapid eye movement versus rapid eye movement sleep on cardiovascular activity.

Goff EA, Nicholas CL, Simonds AK, Trinder J, Morrell MJ.

J Sleep Res. 2010 Mar;19(1 Pt 2):201-6. doi: 10.1111/j.1365-2869.2009.00783.x. Epub 2009 Oct 28.


The influence of age on heart rate variability during morning wakefulness.

Goff EA, Nicholas CL, Malaweera AS, Simonds AK, Trinder J, Morrell MJ.

Clin Auton Res. 2010 Jun;20(3):175-82. doi: 10.1007/s10286-009-0027-0. Epub 2009 Sep 15.


Lives on the line? Ethics and practicalities of duty of care in pandemics and disasters.

Simonds AK, Sokol DK.

Eur Respir J. 2009 Aug;34(2):303-9. doi: 10.1183/09031936.00041609.


Analysis of home support and ventilator malfunction in 1,211 ventilator-dependent patients.

Chatwin M, Heather S, Hanak A, Polkey MI, Simonds AK.

Eur Respir J. 2010 Feb;35(2):310-6. doi: 10.1183/09031936.00073409. Epub 2009 Jul 30.


Autotitrating versus standard noninvasive ventilation: a randomised crossover trial.

Jaye J, Chatwin M, Dayer M, Morrell MJ, Simonds AK.

Eur Respir J. 2009 Mar;33(3):566-71. doi: 10.1183/09031936.00065008.


Adaptive servo-ventilation in heart failure patients with sleep apnea: a real world study.

Hastings PC, Vazir A, Meadows GE, Dayer M, Poole-Wilson PA, McIntyre HF, Morrell MJ, Cowie MR, Simonds AK.

Int J Cardiol. 2010 Feb 18;139(1):17-24. doi: 10.1016/j.ijcard.2008.08.022. Epub 2008 Sep 20.


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