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Items: 1 to 50 of 75

1.

Molecular Determinants of Target Cell Recognition by Human γδ T Cells.

Simões AE, Di Lorenzo B, Silva-Santos B.

Front Immunol. 2018 Apr 27;9:929. doi: 10.3389/fimmu.2018.00929. eCollection 2018. Review.

2.

Tumor-associated neutrophils suppress pro-tumoral IL-17+ γδ T cells through induction of oxidative stress.

Mensurado S, Rei M, Lança T, Ioannou M, Gonçalves-Sousa N, Kubo H, Malissen M, Papayannopoulos V, Serre K, Silva-Santos B.

PLoS Biol. 2018 May 11;16(5):e2004990. doi: 10.1371/journal.pbio.2004990. [Epub ahead of print]

3.

Working in "NK Mode": Natural Killer Group 2 Member D and Natural Cytotoxicity Receptors in Stress-Surveillance by γδ T Cells.

Silva-Santos B, Strid J.

Front Immunol. 2018 Apr 24;9:851. doi: 10.3389/fimmu.2018.00851. eCollection 2018. Review.

4.

The Emerging Complexity of γδT17 Cells.

McKenzie DR, Comerford I, Silva-Santos B, McColl SR.

Front Immunol. 2018 Apr 20;9:796. doi: 10.3389/fimmu.2018.00796. eCollection 2018. Review.

5.

MicroRNA-146a controls functional plasticity in γδ T cells by targeting NOD1.

Schmolka N, Papotto PH, Romero PV, Amado T, Enguita FJ, Amorim A, Rodrigues AF, Gordon KE, Coroadinha AS, Boldin M, Serre K, Buck AH, Gomes AQ, Silva-Santos B.

Sci Immunol. 2018 May 4;3(23). pii: eaao1392. doi: 10.1126/sciimmunol.aao1392.

PMID:
29728425
6.

Control of T cell effector functions by miRNAs.

Inácio DP, Amado T, Silva-Santos B, Gomes AQ.

Cancer Lett. 2018 Jul 28;427:63-73. doi: 10.1016/j.canlet.2018.04.011. Epub 2018 Apr 19.

PMID:
29679611
7.

Got my γδ17 T cells to keep me warm.

Papotto PH, Silva-Santos B.

Nat Immunol. 2018 May;19(5):427-429. doi: 10.1038/s41590-018-0090-6. No abstract available.

PMID:
29670236
8.

Low-Density Lipoprotein Uptake Inhibits the Activation and Antitumor Functions of Human Vγ9Vδ2 T Cells.

Rodrigues NV, Correia DV, Mensurado S, Nóbrega-Pereira S, deBarros A, Kyle-Cezar F, Tutt A, Hayday AC, Norell H, Silva-Santos B, Dias S.

Cancer Immunol Res. 2018 Apr;6(4):448-457. doi: 10.1158/2326-6066.CIR-17-0327. Epub 2018 Jan 22.

PMID:
29358174
9.

Exploiting Temporal Constraints of Clinical Guidelines by Applying OpenEHR Archetypes.

Cintho LMM, Garcia D, da Silva Santos BH, Sacchi L, Quaglini S, Moro CMC.

Stud Health Technol Inform. 2017;245:1322.

PMID:
29295403
10.

Decrease of perforin positive CD3+γδ-T cells in patients with obstructive sleep disordered breathing.

Staats R, Rodrigues R, Barros A, Bacelar-Nicolau L, Aguiar M, Fernandes D, Moreira S, Simões A, Silva-Santos B, Rodrigues JV, Barbara C, de Almeida AB, Moita LF.

Sleep Breath. 2018 Mar;22(1):211-221. doi: 10.1007/s11325-017-1602-6. Epub 2017 Dec 15.

11.

VEGFR2-Mediated Reprogramming of Mitochondrial Metabolism Regulates the Sensitivity of Acute Myeloid Leukemia to Chemotherapy.

Nóbrega-Pereira S, Caiado F, Carvalho T, Matias I, Graça G, Gonçalves LG, Silva-Santos B, Norell H, Dias S.

Cancer Res. 2018 Feb 1;78(3):731-741. doi: 10.1158/0008-5472.CAN-17-1166. Epub 2017 Dec 11.

PMID:
29229602
12.

Multifaceted CK2 in malignant and healthy T cells.

Ribeiro ST, Barata JT, Silva-Santos B.

Oncotarget. 2017 Oct 9;8(53):90622-90623. doi: 10.18632/oncotarget.21700. eCollection 2017 Oct 31. No abstract available.

13.

Innately versatile: γδ17 T cells in inflammatory and autoimmune diseases.

Papotto PH, Reinhardt A, Prinz I, Silva-Santos B.

J Autoimmun. 2018 Feb;87:26-37. doi: 10.1016/j.jaut.2017.11.006. Epub 2017 Dec 6. Review.

14.

IL-23 drives differentiation of peripheral γδ17 T cells from adult bone marrow-derived precursors.

Papotto PH, Gonçalves-Sousa N, Schmolka N, Iseppon A, Mensurado S, Stockinger B, Ribot JC, Silva-Santos B.

EMBO Rep. 2017 Nov;18(11):1957-1967. doi: 10.15252/embr.201744200. Epub 2017 Aug 30.

15.

Primary Tumors Limit Metastasis Formation through Induction of IL15-Mediated Cross-Talk between Patrolling Monocytes and NK Cells.

Kubo H, Mensurado S, Gonçalves-Sousa N, Serre K, Silva-Santos B.

Cancer Immunol Res. 2017 Sep;5(9):812-820. doi: 10.1158/2326-6066.CIR-17-0082. Epub 2017 Aug 15.

PMID:
28811289
16.

Peripheral clonal selection shapes the human γδ T-cell repertoire.

Di Lorenzo B, Déchanet-Merville J, Silva-Santos B.

Cell Mol Immunol. 2017 Sep;14(9):733-735. doi: 10.1038/cmi.2017.51. Epub 2017 Aug 7. No abstract available.

PMID:
28782752
17.

Strong TCRγδ Signaling Prohibits Thymic Development of IL-17A-Secreting γδ T Cells.

Sumaria N, Grandjean CL, Silva-Santos B, Pennington DJ.

Cell Rep. 2017 Jun 20;19(12):2469-2476. doi: 10.1016/j.celrep.2017.05.071.

18.

IL-17+ γδ T cells as kick-starters of inflammation.

Papotto PH, Ribot JC, Silva-Santos B.

Nat Immunol. 2017 May 18;18(6):604-611. doi: 10.1038/ni.3726. Review.

PMID:
28518154
19.

Low-dose ionizing radiation induces therapeutic neovascularization in a pre-clinical model of hindlimb ischemia.

Ministro A, de Oliveira P, Nunes RJ, Dos Santos Rocha A, Correia A, Carvalho T, Rino J, Faísca P, Becker JD, Goyri-O'Neill J, Pina F, Poli E, Silva-Santos B, Pinto F, Mareel M, Serre K, Constantino Rosa Santos S.

Cardiovasc Res. 2017 Jun 1;113(7):783-794. doi: 10.1093/cvr/cvx065.

PMID:
28444128
20.

γδ T cells get adaptive.

Silva-Santos B, Strid J.

Nat Immunol. 2017 Mar 22;18(4):370-372. doi: 10.1038/ni.3705. No abstract available.

21.

Thymic Determinants of γδ T Cell Differentiation.

Muñoz-Ruiz M, Sumaria N, Pennington DJ, Silva-Santos B.

Trends Immunol. 2017 May;38(5):336-344. doi: 10.1016/j.it.2017.01.007. Epub 2017 Mar 9. Review.

PMID:
28285814
22.

Casein kinase 2 controls the survival of normal thymic and leukemic γδ T cells via promotion of AKT signaling.

Ribeiro ST, Tesio M, Ribot JC, Macintyre E, Barata JT, Silva-Santos B.

Leukemia. 2017 Jul;31(7):1603-1610. doi: 10.1038/leu.2016.363. Epub 2016 Nov 30.

23.

Developmental and Functional Assays to Study Murine and Human γδ T Cells.

Ribot JC, Serre K, Silva-Santos B.

Methods Mol Biol. 2017;1514:257-267.

PMID:
27787805
24.

Subset-specific alterations in frequencies and functional signatures of γδ T cells in systemic sclerosis patients.

Henriques A, Silva C, Santiago M, Henriques MJ, Martinho A, Trindade H, da Silva JA, Silva-Santos B, Paiva A.

Inflamm Res. 2016 Dec;65(12):985-994. Epub 2016 Aug 30.

PMID:
27576328
25.

Delta One T Cells for Immunotherapy of Chronic Lymphocytic Leukemia: Clinical-Grade Expansion/Differentiation and Preclinical Proof of Concept.

Almeida AR, Correia DV, Fernandes-Platzgummer A, da Silva CL, da Silva MG, Anjos DR, Silva-Santos B.

Clin Cancer Res. 2016 Dec 1;22(23):5795-5804. Epub 2016 Jun 15.

26.

TCR signal strength controls thymic differentiation of discrete proinflammatory γδ T cell subsets.

Muñoz-Ruiz M, Ribot JC, Grosso AR, Gonçalves-Sousa N, Pamplona A, Pennington DJ, Regueiro JR, Fernández-Malavé E, Silva-Santos B.

Nat Immunol. 2016 Jun;17(6):721-727. doi: 10.1038/ni.3424. Epub 2016 Apr 4.

27.

Effector γδ T Cell Differentiation Relies on Master but Not Auxiliary Th Cell Transcription Factors.

Barros-Martins J, Schmolka N, Fontinha D, Pires de Miranda M, Simas JP, Brok I, Ferreira C, Veldhoen M, Silva-Santos B, Serre K.

J Immunol. 2016 May 1;196(9):3642-52. doi: 10.4049/jimmunol.1501921. Epub 2016 Mar 18.

28.

Intra-tumour heterogeneity - going beyond genetics.

Caiado F, Silva-Santos B, Norell H.

FEBS J. 2016 Jun;283(12):2245-58. doi: 10.1111/febs.13705. Epub 2016 Apr 1. Review.

29.

γδ T cells in cancer.

Silva-Santos B, Serre K, Norell H.

Nat Rev Immunol. 2015 Nov;15(11):683-91. doi: 10.1038/nri3904. Epub 2015 Oct 9. Review.

PMID:
26449179
30.

Cross-regulation between cytokine and microRNA pathways in T cells.

Amado T, Schmolka N, Metwally H, Silva-Santos B, Gomes AQ.

Eur J Immunol. 2015 Jun;45(6):1584-95. doi: 10.1002/eji.201545487. Epub 2015 May 13. Review.

31.

Epigenetic and transcriptional regulation of γδ T cell differentiation: Programming cells for responses in time and space.

Schmolka N, Wencker M, Hayday AC, Silva-Santos B.

Semin Immunol. 2015 Feb;27(1):19-25. doi: 10.1016/j.smim.2015.01.001. Epub 2015 Feb 25. Review.

PMID:
25726512
32.

Five Layers of Receptor Signaling in γδ T-Cell Differentiation and Activation.

Ribeiro ST, Ribot JC, Silva-Santos B.

Front Immunol. 2015 Jan 26;6:15. doi: 10.3389/fimmu.2015.00015. eCollection 2015. Review.

33.

The emerging Protumor role of γδ T lymphocytes: implications for cancer immunotherapy.

Rei M, Pennington DJ, Silva-Santos B.

Cancer Res. 2015 Mar 1;75(5):798-802. doi: 10.1158/0008-5472.CAN-14-3228. Epub 2015 Feb 6. Review.

34.

Classification of current anticancer immunotherapies.

Galluzzi L, Vacchelli E, Bravo-San Pedro JM, Buqué A, Senovilla L, Baracco EE, Bloy N, Castoldi F, Abastado JP, Agostinis P, Apte RN, Aranda F, Ayyoub M, Beckhove P, Blay JY, Bracci L, Caignard A, Castelli C, Cavallo F, Celis E, Cerundolo V, Clayton A, Colombo MP, Coussens L, Dhodapkar MV, Eggermont AM, Fearon DT, Fridman WH, Fučíková J, Gabrilovich DI, Galon J, Garg A, Ghiringhelli F, Giaccone G, Gilboa E, Gnjatic S, Hoos A, Hosmalin A, Jäger D, Kalinski P, Kärre K, Kepp O, Kiessling R, Kirkwood JM, Klein E, Knuth A, Lewis CE, Liblau R, Lotze MT, Lugli E, Mach JP, Mattei F, Mavilio D, Melero I, Melief CJ, Mittendorf EA, Moretta L, Odunsi A, Okada H, Palucka AK, Peter ME, Pienta KJ, Porgador A, Prendergast GC, Rabinovich GA, Restifo NP, Rizvi N, Sautès-Fridman C, Schreiber H, Seliger B, Shiku H, Silva-Santos B, Smyth MJ, Speiser DE, Spisek R, Srivastava PK, Talmadge JE, Tartour E, Van Der Burg SH, Van Den Eynde BJ, Vile R, Wagner H, Weber JS, Whiteside TL, Wolchok JD, Zitvogel L, Zou W, Kroemer G.

Oncotarget. 2014 Dec 30;5(24):12472-508. Review.

35.

Chicago 2014--30 years of γδ T cells.

Bonneville M, Chen ZW, Déchanet-Merville J, Eberl M, Fournié JJ, Jameson JM, Lopez RD, Massaia M, Silva-Santos B.

Cell Immunol. 2015 Jul;296(1):3-9. doi: 10.1016/j.cellimm.2014.11.001. Epub 2014 Nov 8.

36.

Murine CD27(-) Vγ6(+) γδ T cells producing IL-17A promote ovarian cancer growth via mobilization of protumor small peritoneal macrophages.

Rei M, Gonçalves-Sousa N, Lança T, Thompson RG, Mensurado S, Balkwill FR, Kulbe H, Pennington DJ, Silva-Santos B.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):E3562-70. doi: 10.1073/pnas.1403424111. Epub 2014 Aug 11.

37.

Human γδ thymocytes are functionally immature and differentiate into cytotoxic type 1 effector T cells upon IL-2/IL-15 signaling.

Ribot JC, Ribeiro ST, Correia DV, Sousa AE, Silva-Santos B.

J Immunol. 2014 Mar 1;192(5):2237-43. doi: 10.4049/jimmunol.1303119. Epub 2014 Jan 31.

38.

Molecular Mechanisms of Differentiation of Murine Pro-Inflammatory γδ T Cell Subsets.

Serre K, Silva-Santos B.

Front Immunol. 2013 Dec 5;4:431. doi: 10.3389/fimmu.2013.00431. Review.

39.

Recruitment of γδ T lymphocytes to tumors: A new role for the pleiotropic chemokine CCL2.

Lança T, Silva-Santos B.

Oncoimmunology. 2013 Aug 1;2(8):e25461. Epub 2013 Jul 1.

40.

At the Bench: Preclinical rationale for exploiting NK cells and γδ T lymphocytes for the treatment of high-risk leukemias.

Norell H, Moretta A, Silva-Santos B, Moretta L.

J Leukoc Biol. 2013 Dec;94(6):1123-39. doi: 10.1189/jlb.0613312. Epub 2013 Oct 9. Review.

PMID:
24108703
41.

Epigenetic and transcriptional signatures of stable versus plastic differentiation of proinflammatory γδ T cell subsets.

Schmolka N, Serre K, Grosso AR, Rei M, Pennington DJ, Gomes AQ, Silva-Santos B.

Nat Immunol. 2013 Oct;14(10):1093-1100. doi: 10.1038/ni.2702. Epub 2013 Sep 1.

42.

Functional development of γδ T cells.

Prinz I, Silva-Santos B, Pennington DJ.

Eur J Immunol. 2013 Aug;43(8):1988-94. doi: 10.1002/eji.201343759. Review.

43.

Protective role of the inflammatory CCR2/CCL2 chemokine pathway through recruitment of type 1 cytotoxic γδ T lymphocytes to tumor beds.

Lança T, Costa MF, Gonçalves-Sousa N, Rei M, Grosso AR, Penido C, Silva-Santos B.

J Immunol. 2013 Jun 15;190(12):6673-80. doi: 10.4049/jimmunol.1300434. Epub 2013 May 17.

44.

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway.

Coquet JM, Ribot JC, Bąbała N, Middendorp S, van der Horst G, Xiao Y, Neves JF, Fonseca-Pereira D, Jacobs H, Pennington DJ, Silva-Santos B, Borst J.

J Exp Med. 2013 Apr 8;210(4):715-28. doi: 10.1084/jem.20112061. Epub 2013 Apr 1.

45.

Natural cytotoxicity receptors: broader expression patterns and functions in innate and adaptive immune cells.

Hudspeth K, Silva-Santos B, Mavilio D.

Front Immunol. 2013 Mar 20;4:69. doi: 10.3389/fimmu.2013.00069. eCollection 2013.

46.

Tumor cell recognition by γδ T lymphocytes: T-cell receptor vs. NK-cell receptors.

Correia DV, Lopes A, Silva-Santos B.

Oncoimmunology. 2013 Jan 1;2(1):e22892.

47.

Differentiation and activation of γδ T Lymphocytes: Focus on CD27 and CD28 costimulatory receptors.

Ribot JC, Silva-Santos B.

Adv Exp Med Biol. 2013;785:95-105. doi: 10.1007/978-1-4614-6217-0_11. Review.

PMID:
23456842
48.

γδ T-cell conference 2012: close encounters for the fifth time.

Silva-Santos B, Schamel WW, Fisch P, Eberl M.

Eur J Immunol. 2012 Dec;42(12):3101-5. doi: 10.1002/eji.201270101. Erratum in: Eur J Immunol. 2013 Feb;43(2):562.

49.
50.

B7-CD28 costimulatory signals control the survival and proliferation of murine and human γδ T cells via IL-2 production.

Ribot JC, Debarros A, Mancio-Silva L, Pamplona A, Silva-Santos B.

J Immunol. 2012 Aug 1;189(3):1202-8. doi: 10.4049/jimmunol.1200268. Epub 2012 Jun 25.

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