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Sarcopenic obesity and overall mortality: Results from the application of novel models of body composition phenotypes to the National Health and Nutrition Examination Survey 1999-2004.

Van Aller C, Lara J, Stephan BCM, Donini LM, Heymsfield S, Katzmarzyk PT, Wells JCK, Prado CM, Siervo M.

Clin Nutr. 2018 Feb 15. pii: S0261-5614(18)30042-6. doi: 10.1016/j.clnu.2018.01.022. [Epub ahead of print]


Association between body composition and pulmonary function in children and young people with cystic fibrosis.

Calella P, Valerio G, Thomas M, McCabe H, Taylor J, Brodlie M, Siervo M.

Nutrition. 2018 Apr;48:73-76. doi: 10.1016/j.nut.2017.10.026. Epub 2017 Dec 5.


Longitudinal Effect of Stroke on Cognition: A Systematic Review.

Tang EY, Amiesimaka O, Harrison SL, Green E, Price C, Robinson L, Siervo M, Stephan BC.

J Am Heart Assoc. 2018 Jan 15;7(2). pii: e006443. doi: 10.1161/JAHA.117.006443. Review.


A pilot study of a non-invasive oral nitrate stable isotopic method suggests that arginine and citrulline supplementation increases whole-body NO production in Tanzanian children with sickle cell disease.

Marealle AI, Siervo M, Wassel S, Bluck L, Prentice AM, Minzi O, Sasi P, Kamuhabwa A, Soka D, Makani J, Cox SE.

Nitric Oxide. 2018 Apr 1;74:19-22. doi: 10.1016/j.niox.2017.12.009. Epub 2018 Jan 2.


Low protein intake, muscle strength and physical performance in the very old: The Newcastle 85+ Study.

Granic A, Mendonça N, Sayer AA, Hill TR, Davies K, Adamson A, Siervo M, Mathers JC, Jagger C.

Clin Nutr. 2017 Nov 16. pii: S0261-5614(17)31403-6. doi: 10.1016/j.clnu.2017.11.005. [Epub ahead of print]


Manipulation of Contents of Nitrate, Phenolic Acids, Chlorophylls, and Carotenoids in Lettuce (Lactuca sativa L.) via Contrasting Responses to Nitrogen Fertilizer When Grown in a Controlled Environment.

Qadir O, Siervo M, Seal CJ, Brandt K.

J Agric Food Chem. 2017 Nov 22;65(46):10003-10010. doi: 10.1021/acs.jafc.7b03675. Epub 2017 Nov 9.


Prevalence and determinants of low protein intake in very old adults: insights from the Newcastle 85+ Study.

Mendonça N, Granic A, Mathers JC, Hill TR, Siervo M, Adamson AJ, Jagger C.

Eur J Nutr. 2017 Sep 25. doi: 10.1007/s00394-017-1537-5. [Epub ahead of print]


Cross-sectional associations between metabolic syndrome and performance across cognitive domains: A systematic review.

Alcorn T, Hart E, Smith AE, Feuerriegel D, Stephan BCM, Siervo M, Keage HAD.

Appl Neuropsychol Adult. 2017 Sep 25:1-14. doi: 10.1080/23279095.2017.1363039. [Epub ahead of print]


Pathophysiology of exercise intolerance in chronic diseases: the role of diminished cardiac performance in mitochondrial and heart failure patients.

McCoy J, Bates M, Eggett C, Siervo M, Cassidy S, Newman J, Moore SA, Gorman G, Trenell MI, Velicki L, Seferovic PM, Cleland JGF, MacGowan GA, Turnbull DM, Jakovljevic DG.

Open Heart. 2017 Jul 28;4(2):e000632. doi: 10.1136/openhrt-2017-000632. eCollection 2017.


Acute effects of video-game playing versus television viewing on stress markers and food intake in overweight and obese young men: A randomised controlled trial.

Siervo M, Gan J, Fewtrell MS, Cortina-Borja M, Wells JCK.

Appetite. 2018 Jan 1;120:100-108. doi: 10.1016/j.appet.2017.08.018. Epub 2017 Aug 24.


Cardiovascular Disease, the Nitric Oxide Pathway and Risk of Cognitive Impairment and Dementia.

Stephan BCM, Harrison SL, Keage HAD, Babateen A, Robinson L, Siervo M.

Curr Cardiol Rep. 2017 Aug 11;19(9):87. doi: 10.1007/s11886-017-0898-y. Review.


Lycopene and tomato and risk of cardiovascular diseases: A systematic review and meta-analysis of epidemiological evidence.

Cheng HM, Koutsidis G, Lodge JK, Ashor AW, Siervo M, Lara J.

Crit Rev Food Sci Nutr. 2017 Aug 11:1-18. doi: 10.1080/10408398.2017.1362630. [Epub ahead of print]


Effects of Dietary Nitrate Supplementation on Physiological Responses, Cognitive Function, and Exercise Performance at Moderate and Very-High Simulated Altitude.

Shannon OM, Duckworth L, Barlow MJ, Deighton K, Matu J, Williams EL, Woods D, Xie L, Stephan BCM, Siervo M, O'Hara JP.

Front Physiol. 2017 Jun 9;8:401. doi: 10.3389/fphys.2017.00401. eCollection 2017.


"Beet-ing" the Mountain: A Review of the Physiological and Performance Effects of Dietary Nitrate Supplementation at Simulated and Terrestrial Altitude.

Shannon OM, McGawley K, Nybäck L, Duckworth L, Barlow MJ, Woods D, Siervo M, O'Hara JP.

Sports Med. 2017 Nov;47(11):2155-2169. doi: 10.1007/s40279-017-0744-9.


Does hypoxia play a role in the development of sarcopenia in humans? Mechanistic insights from the Caudwell Xtreme Everest Expedition.

Wandrag L, Siervo M, Riley HL, Khosravi M, Fernandez BO, Leckstrom CA, Martin DS, Mitchell K, Levett DZH, Montgomery HE, Mythen MG, Stroud MA, Grocott MPW, Feelisch M; Caudwell Xtreme Everest Research Group.

Redox Biol. 2017 Oct;13:60-68. doi: 10.1016/j.redox.2017.05.004. Epub 2017 May 8.


Dietary nitrate does not modify blood pressure and cardiac output at rest and during exercise in older adults: a randomised cross-over study.

Oggioni C, Jakovljevic DG, Klonizakis M, Ashor AW, Ruddock A, Ranchordas M, Williams E, Siervo M.

Int J Food Sci Nutr. 2018 Feb;69(1):74-83. doi: 10.1080/09637486.2017.1328666. Epub 2017 May 31.


Prevalence of Sarcopenic Obesity in Adults with Class II/III Obesity Using Different Diagnostic Criteria.

Johnson Stoklossa CA, Sharma AM, Forhan M, Siervo M, Padwal RS, Prado CM.

J Nutr Metab. 2017;2017:7307618. doi: 10.1155/2017/7307618. Epub 2017 Mar 22.


Vitamin D Status, Muscle Strength and Physical Performance Decline in Very Old Adults: A Prospective Study.

Granic A, Hill TR, Davies K, Jagger C, Adamson A, Siervo M, Kirkwood TB, Mathers JC, Sayer AA.

Nutrients. 2017 Apr 13;9(4). pii: E379. doi: 10.3390/nu9040379.


Medium-term effects of dietary nitrate supplementation on systolic and diastolic blood pressure in adults: a systematic review and meta-analysis.

Ashor AW, Lara J, Siervo M.

J Hypertens. 2017 Jul;35(7):1353-1359. doi: 10.1097/HJH.0000000000001305. Review.


Effects of vitamin C supplementation on glycaemic control: a systematic review and meta-analysis of randomised controlled trials.

Ashor AW, Werner AD, Lara J, Willis ND, Mathers JC, Siervo M.

Eur J Clin Nutr. 2017 Dec;71(12):1371-1380. doi: 10.1038/ejcn.2017.24. Epub 2017 Mar 15. Review.


Dietary nitrate supplementation enhances short but not longer duration running time-trial performance.

Shannon OM, Barlow MJ, Duckworth L, Williams E, Wort G, Woods D, Siervo M, O'Hara JP.

Eur J Appl Physiol. 2017 Apr;117(4):775-785. doi: 10.1007/s00421-017-3580-6. Epub 2017 Mar 1.


Tomato and lycopene supplementation and cardiovascular risk factors: A systematic review and meta-analysis.

Cheng HM, Koutsidis G, Lodge JK, Ashor A, Siervo M, Lara J.

Atherosclerosis. 2017 Feb;257:100-108. doi: 10.1016/j.atherosclerosis.2017.01.009. Epub 2017 Jan 13. Review.


Protocol of a feasibility study for cognitive assessment of an ageing cohort within the Southeast Asia Community Observatory (SEACO), Malaysia.

Mohan D, Stephan BC, Allotey P, Jagger C, Pearce M, Siervo M, Reidpath DD.

BMJ Open. 2017 Jan 19;7(1):e013635. doi: 10.1136/bmjopen-2016-013635.


Inorganic Nitrate Mimics Exercise-Stimulated Muscular Fiber-Type Switching and Myokine and γ-Aminobutyric Acid Release.

Roberts LD, Ashmore T, McNally BD, Murfitt SA, Fernandez BO, Feelisch M, Lindsay R, Siervo M, Williams EA, Murray AJ, Griffin JL.

Diabetes. 2017 Mar;66(3):674-688. doi: 10.2337/db16-0843. Epub 2016 Dec 27.


Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity.

Cuthbertson DJ, Babraj J, Leese G, Siervo M.

Clin Nutr. 2017 Dec;36(6):1716-1719. doi: 10.1016/j.clnu.2016.11.012. Epub 2016 Nov 25.


Dietary nitrate does not affect physical activity or outcomes in healthy older adults in a randomized, cross-over trial.

Siervo M, Oggioni C, Jakovljevic DG, Trenell M, Mathers JC, Houghton D, Celis-Morales C, Ashor AW, Ruddock A, Ranchordas M, Klonizakis M, Williams EA.

Nutr Res. 2016 Dec;36(12):1361-1369. doi: 10.1016/j.nutres.2016.11.004. Epub 2016 Nov 14.


Association between ratio indexes of body composition phenotypes and metabolic risk in Italian adults.

Powell M, Lara J, Mocciaro G, Prado CM, Battezzati A, Leone A, Tagliabue A, de Amicis R, Vignati L, Bertoli S, Siervo M.

Clin Obes. 2016 Dec;6(6):365-375. doi: 10.1111/cob.12165. Epub 2016 Nov 21.


Predicting Risk of Cognitive Decline in Very Old Adults Using Three Models: The Framingham Stroke Risk Profile; the Cardiovascular Risk Factors, Aging, and Dementia Model; and Oxi-Inflammatory Biomarkers.

Harrison SL, de Craen AJ, Kerse N, Teh R, Granic A, Davies K, Wesnes KA, den Elzen WP, Gussekloo J, Kirkwood TB, Robinson L, Jagger C, Siervo M, Stephan BC.

J Am Geriatr Soc. 2017 Feb;65(2):381-389. doi: 10.1111/jgs.14532. Epub 2016 Nov 14.


Inorganic Nitrate Supplementation in Young and Old Obese Adults Does Not Affect Acute Glucose and Insulin Responses but Lowers Oxidative Stress.

Ashor AW, Chowdhury S, Oggioni C, Qadir O, Brandt K, Ishaq A, Mathers JC, Saretzki G, Siervo M.

J Nutr. 2016 Nov;146(11):2224-2232. Epub 2016 Oct 12.


Age-related decline in cardiac autonomic function is not attenuated with increased physical activity.

Njemanze H, Warren C, Eggett C, MacGowan GA, Bates MG, Siervo M, Ivkovic S, Trenell MI, Jakovljevic DG.

Oncotarget. 2016 Nov 22;7(47):76390-76397. doi: 10.18632/oncotarget.12403.


Dietary nitrate supplementation enhances high-intensity running performance in moderate normobaric hypoxia, independent of aerobic fitness.

Shannon OM, Duckworth L, Barlow MJ, Woods D, Lara J, Siervo M, O'Hara JP.

Nitric Oxide. 2016 Sep 30;59:63-70. doi: 10.1016/j.niox.2016.08.001. Epub 2016 Aug 20.


Micronutrient intake and food sources in the very old: analysis of the Newcastle 85+ Study.

Mendonça N, Hill TR, Granic A, Davies K, Collerton J, Mathers JC, Siervo M, Wrieden WL, Seal CJ, Kirkwood TB, Jagger C, Adamson AJ.

Br J Nutr. 2016 Aug;116(4):751-61. doi: 10.1017/S0007114516002567. Epub 2016 Jul 1.


Is Obesity Associated with Altered Energy Expenditure?

Carneiro IP, Elliott SA, Siervo M, Padwal R, Bertoli S, Battezzati A, Prado CM.

Adv Nutr. 2016 May 16;7(3):476-87. doi: 10.3945/an.115.008755. Print 2016 May. Review.


What do we know about the nutritional status of the very old? Insights from three cohorts of advanced age from the UK and New Zealand.

Hill TR, Mendonça N, Granic A, Siervo M, Jagger C, Seal CJ, Kerse N, Wham C, Adamson AJ, Mathers JC.

Proc Nutr Soc. 2016 Aug;75(3):420-30. doi: 10.1017/S0029665116000203. Epub 2016 May 11. Review.


Macronutrient intake and food sources in the very old: analysis of the Newcastle 85+ Study.

Mendonça N, Hill TR, Granic A, Davies K, Collerton J, Mathers JC, Siervo M, Wrieden WL, Seal CJ, Kirkwood TB, Jagger C, Adamson AJ.

Br J Nutr. 2016 Jun;115(12):2170-80. doi: 10.1017/S0007114516001379. Epub 2016 Apr 18.


Effect of Dietary Patterns on Muscle Strength and Physical Performance in the Very Old: Findings from the Newcastle 85+ Study.

Granic A, Jagger C, Davies K, Adamson A, Kirkwood T, Hill TR, Siervo M, Mathers JC, Sayer AA.

PLoS One. 2016 Mar 2;11(3):e0149699. doi: 10.1371/journal.pone.0149699. eCollection 2016.


Dietary protein intake in sarcopenic obese older women.

Muscariello E, Nasti G, Siervo M, Di Maro M, Lapi D, D'Addio G, Colantuoni A.

Clin Interv Aging. 2016 Feb 5;11:133-40. doi: 10.2147/CIA.S96017. eCollection 2016.


Effects of vitamin D supplementation on endothelial function: a systematic review and meta-analysis of randomised clinical trials.

Hussin AM, Ashor AW, Schoenmakers I, Hill T, Mathers JC, Siervo M.

Eur J Nutr. 2017 Apr;56(3):1095-1104. doi: 10.1007/s00394-016-1159-3. Epub 2016 Feb 5. Review.


Dietary Patterns High in Red Meat, Potato, Gravy, and Butter Are Associated with Poor Cognitive Functioning but Not with Rate of Cognitive Decline in Very Old Adults.

Granic A, Davies K, Adamson A, Kirkwood T, Hill TR, Siervo M, Mathers JC, Jagger C.

J Nutr. 2016 Feb;146(2):265-74. doi: 10.3945/jn.115.216952. Epub 2016 Jan 6.


The effect of age on the relationship between cardiac and vascular function.

Houghton D, Jones TW, Cassidy S, Siervo M, MacGowan GA, Trenell MI, Jakovljevic DG.

Mech Ageing Dev. 2016 Jan;153:1-6. doi: 10.1016/j.mad.2015.11.001. Epub 2015 Nov 15.


Dietary Patterns and Socioeconomic Status in the Very Old: The Newcastle 85+ Study.

Granic A, Davies K, Adamson A, Kirkwood T, Hill TR, Siervo M, Mathers JC, Jagger C.

PLoS One. 2015 Oct 21;10(10):e0139713. doi: 10.1371/journal.pone.0139713. eCollection 2015.


Serum 25-hydroxyvitamin D concentration and its determinants in the very old: the Newcastle 85+ Study.

Hill TR, Granic A, Davies K, Collerton J, Martin-Ruiz C, Siervo M, Mathers JC, Adamson AJ, Francis RM, Pearce SH, Razvi S, Kirkwood TBL, Jagger C.

Osteoporos Int. 2016 Mar;27(3):1199-1208. doi: 10.1007/s00198-015-3366-9. Epub 2015 Oct 14.


Effects of handgrip exercise or inorganic nitrate supplementation on 24-h ambulatory blood pressure and peripheral arterial function in overweight and obese middle age and older adults: A pilot RCT.

Lara J, Ogbonmwan I, Oggioni C, Zheng D, Qadir O, Ashor A, Brandt K, Mathers JC, Siervo M.

Maturitas. 2015 Oct;82(2):228-35. doi: 10.1016/j.maturitas.2015.07.028. Epub 2015 Aug 1.


Calorie for Calorie, Dietary Fat Restriction Results in More Body Fat Loss than Carbohydrate Restriction in People with Obesity.

Hall KD, Bemis T, Brychta R, Chen KY, Courville A, Crayner EJ, Goodwin S, Guo J, Howard L, Knuth ND, Miller BV 3rd, Prado CM, Siervo M, Skarulis MC, Walter M, Walter PJ, Yannai L.

Cell Metab. 2015 Sep 1;22(3):427-36. doi: 10.1016/j.cmet.2015.07.021. Epub 2015 Aug 13.


Age-related changes in basal substrate oxidation and visceral adiposity and their association with metabolic syndrome.

Siervo M, Lara J, Celis-Morales C, Vacca M, Oggioni C, Battezzati A, Leone A, Tagliabue A, Spadafranca A, Bertoli S.

Eur J Nutr. 2016 Jun;55(4):1755-67. doi: 10.1007/s00394-015-0993-z. Epub 2015 Aug 2.


Systematic review and meta-analysis of randomised controlled trials testing the effects of vitamin C supplementation on blood lipids.

Ashor AW, Siervo M, van der Velde F, Willis ND, Mathers JC.

Clin Nutr. 2016 Jun;35(3):626-37. doi: 10.1016/j.clnu.2015.05.021. Epub 2015 Jun 17. Review.


Socio-demographic patterns of physical activity and sedentary behaviour in Chile: results from the National Health Survey 2009-2010.

Celis-Morales C, Salas C, Alduhishy A, Sanzana R, Martínez MA, Leiva A, Diaz X, Martínez C, Álvarez C, Leppe J, Munro CA, Siervo M, Willis ND.

J Public Health (Oxf). 2016 Jun;38(2):e98-e105. doi: 10.1093/pubmed/fdv079. Epub 2015 Jun 25.


Ageing modifies the effects of beetroot juice supplementation on 24-hour blood pressure variability: An individual participant meta-analysis.

Siervo M, Lara J, Jajja A, Sutyarjoko A, Ashor AW, Brandt K, Qadir O, Mathers JC, Benjamin N, Winyard PG, Anning C, Shore A, Gilchrist M.

Nitric Oxide. 2015 May 1;47:97-105. doi: 10.1016/j.niox.2015.04.007. Epub 2015 Apr 29.


Effect of vitamin C and vitamin E supplementation on endothelial function: a systematic review and meta-analysis of randomised controlled trials.

Ashor AW, Siervo M, Lara J, Oggioni C, Afshar S, Mathers JC.

Br J Nutr. 2015 Apr 28;113(8):1182-94. doi: 10.1017/S0007114515000227. Review.


Imposed rate and extent of weight loss in obese men and adaptive changes in resting and total energy expenditure.

Siervo M, Faber P, Lara J, Gibney ER, Milne E, Ritz P, Lobley GE, Elia M, Stubbs RJ, Johnstone AM.

Metabolism. 2015 Aug;64(8):896-904. doi: 10.1016/j.metabol.2015.03.011. Epub 2015 Apr 8.


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