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Items: 3


Experimental mutagenesis of huntingtin to map cleavage sites: different outcomes in cell and mouse models.

Tebbenkamp AT, Xu G, Siemienski ZB, Janus C, Fromholt SE, Brown HH, Swing D, Tessarollo L, Borchelt DR.

J Huntingtons Dis. 2014;3(1):73-86. doi: 10.3233/JHD-130087.


Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models".

Price AR, Xu G, Siemienski ZB, Smithson LA, Borchelt DR, Golde TE, Felsenstein KM.

Science. 2013 May 24;340(6135):924-d. doi: 10.1126/science.1234089.


Analysis of proteolytic processes and enzymatic activities in the generation of huntingtin n-terminal fragments in an HEK293 cell model.

Tebbenkamp AT, Crosby KW, Siemienski ZB, Brown HH, Golde TE, Borchelt DR.

PLoS One. 2012;7(12):e50750. doi: 10.1371/journal.pone.0050750. Epub 2012 Dec 7.

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