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Items: 16

1.

Antagonists of IGF:Vitronectin Interactions Inhibit IGF-I-Induced Breast Cancer Cell Functions.

Kashyap AS, Shooter GK, Shokoohmand A, McGovern J, Sivaramakrishnan M, Croll TI, Cane G, Leavesley DI, Söderberg O, Upton Z, Hollier BG.

Mol Cancer Ther. 2016 Jul;15(7):1602-13. doi: 10.1158/1535-7163.MCT-15-0907. Epub 2016 May 9. Erratum in: Mol Cancer Ther. 2016 Dec;15(12 ):3120.

2.

Uric acid and xanthine oxidoreductase in wound healing.

Fernandez ML, Upton Z, Shooter GK.

Curr Rheumatol Rep. 2014 Feb;16(2):396. doi: 10.1007/s11926-013-0396-1. Review.

PMID:
24357442
3.

Lysine residues of IGF-I are substrates for transglutaminases and modulate downstream IGF-I signalling.

Sivaramakrishnan M, Croll TI, Gupta R, Stupar D, Van Lonkhuyzen DR, Upton Z, Shooter GK.

Biochim Biophys Acta. 2013 Dec;1833(12):3176-3185. doi: 10.1016/j.bbamcr.2013.09.002. Epub 2013 Sep 11.

4.

A pre-clinical functional assessment of an acellular scaffold intended for the treatment of hard-to-heal wounds.

Shooter GK, Van Lonkhuyzen DR, Croll TI, Cao Y, Xie Y, Broadbent JA, Stupar D, Lynam EC, Upton Z.

Int Wound J. 2015 Apr;12(2):160-8. doi: 10.1111/iwj.12073. Epub 2013 Apr 5.

PMID:
23556541
5.

Transglutaminases and receptor tyrosine kinases.

Sivaramakrishnan M, Shooter GK, Upton Z, Croll TI.

Amino Acids. 2013 Jan;44(1):19-24. doi: 10.1007/s00726-011-1113-x. Epub 2011 Oct 11. Review.

PMID:
21986960
6.

Elevated uric acid correlates with wound severity.

Fernandez ML, Upton Z, Edwards H, Finlayson K, Shooter GK.

Int Wound J. 2012 Apr;9(2):139-49. doi: 10.1111/j.1742-481X.2011.00870.x. Epub 2011 Oct 4.

PMID:
21973196
7.

Human pilot studies reveal the potential of a vitronectin: growth factor complex as a treatment for chronic wounds.

Upton Z, Wallace HJ, Shooter GK, van Lonkhuyzen DR, Yeoh-Ellerton S, Rayment EA, Fleming JM, Broszczak D, Queen D, Sibbald RG, Leavesley DI, Stacey MC.

Int Wound J. 2011 Oct;8(5):522-32. doi: 10.1111/j.1742-481X.2011.00859.x.

PMID:
21914133
8.

A peptidomimetic inhibitor of matrix metalloproteinases containing a tetherable linker group.

Cao Y, Croll TI, Rizzi SC, Shooter GK, Edwards H, Finlayson K, Upton Z, Dargaville TR.

J Biomed Mater Res A. 2011 Mar 15;96(4):663-72. doi: 10.1002/jbm.a.33027. Epub 2011 Jan 25.

PMID:
21268242
9.

Mechanistic investigations into interactions between IGF-I and IGFBPs and their impact on facilitating cell migration on vitronectin.

Kricker JA, Hyde CE, Van Lonkhuyzen DR, Hollier BG, Shooter GK, Leavesley DI, Herington AC, Upton Z.

Growth Factors. 2010 Oct;28(5):359-69. doi: 10.3109/08977194.2010.494603.

PMID:
20569097
10.

Increased matrix metalloproteinase-9 (MMP-9) activity observed in chronic wound fluid is related to the clinical severity of the ulcer.

Rayment EA, Upton Z, Shooter GK.

Br J Dermatol. 2008 May;158(5):951-61. doi: 10.1111/j.1365-2133.2008.08462.x. Epub 2008 Feb 16.

PMID:
18284390
11.

Attenuation of protease activity in chronic wound fluid with bisphosphonate-functionalised hydrogels.

Rayment EA, Dargaville TR, Shooter GK, George GA, Upton Z.

Biomaterials. 2008 Apr;29(12):1785-95. doi: 10.1016/j.biomaterials.2007.12.043. Epub 2008 Jan 31.

PMID:
18241915
12.

Chimeric vitronectin:insulin-like growth factor proteins enhance cell growth and migration through co-activation of receptors.

Van Lonkhuyzen DR, Hollier BG, Shooter GK, Leavesley DI, Upton Z.

Growth Factors. 2007 Oct;25(5):295-308. doi: 10.1080/08977190701803752.

PMID:
18236208
13.

Development of an enhanced proteomic method to detect prognostic and diagnostic markers of healing in chronic wound fluid.

Fernandez ML, Broadbent JA, Shooter GK, Malda J, Upton Z.

Br J Dermatol. 2008 Feb;158(2):281-90. Epub 2007 Dec 6.

PMID:
18070206
14.

Insulin-like growth factor I and its binding proteins: a study of the binding interface using B-domain analogues.

Magee BA, Shooter GK, Wallace JC, Francis GL.

Biochemistry. 1999 Nov 30;38(48):15863-70.

PMID:
10625451
15.

Secondary structure determination of 15N-labelled human Long-[Arg-3]-insulin-like growth factor 1 by multidimensional NMR spectroscopy.

Laajoki LG, Le Breton E, Shooter GK, Wallace JC, Francis GL, Carver JA, Keniry MA.

FEBS Lett. 1997 Dec 22;420(1):97-102.

16.

Insulin-like growth factor (IGF)-I A- and B-domain analogues with altered type 1 IGF and insulin receptor binding specificities.

Shooter GK, Magee B, Soos MA, Francis GL, Siddle K, Wallace JC.

J Mol Endocrinol. 1996 Dec;17(3):237-46.

PMID:
8981230

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