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Enabling clearance predictions to emerge from in silico actions of quasi-autonomous hepatocyte components.

Sheikh-Bahaei S, Hunt CA.

Drug Metab Dispos. 2011 Oct;39(10):1910-20. doi: 10.1124/dmd.111.038703. Epub 2011 Jul 18.


Computational experiments reveal plausible mechanisms for changing patterns of hepatic zonation of xenobiotic clearance and hepatotoxicity.

Sheikh-Bahaei S, Maher JJ, Anthony Hunt C.

J Theor Biol. 2010 Aug 21;265(4):718-33. doi: 10.1016/j.jtbi.2010.06.011. Epub 2010 Jun 10.


At the biological modeling and simulation frontier.

Hunt CA, Ropella GE, Lam TN, Tang J, Kim SH, Engelberg JA, Sheikh-Bahaei S.

Pharm Res. 2009 Nov;26(11):2369-400. doi: 10.1007/s11095-009-9958-3. Epub 2009 Sep 9. Review.

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