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Items: 1 to 50 of 289

1.

Developing a Biased Unmatched Bivalent Ligand (BUmBL) Design Strategy to Target the GPCR Homodimer Allosteric Signaling (cAMP over β-Arrestin2 Recruitment) Within the Melanocortin Receptors.

Lensing CJ, Freeman KT, Schnell SM, Speth RC, Zarth AT, Haskell-Luevano C.

J Med Chem. 2018 Apr 18. doi: 10.1021/acs.jmedchem.8b00238. [Epub ahead of print]

PMID:
29669202
2.

Consistent associations with beneficial bacteria in the seed endosphere of barley (Hordeum vulgare L.).

Rahman MM, Flory E, Koyro HW, Abideen Z, Schikora A, Suarez C, Schnell S, Cardinale M.

Syst Appl Microbiol. 2018 Mar 13. pii: S0723-2020(18)30084-5. doi: 10.1016/j.syapm.2018.02.003. [Epub ahead of print]

PMID:
29567394
3.

STRENDA DB: enabling the validation and sharing of enzyme kinetics data.

Swainston N, Baici A, Bakker BM, Cornish-Bowden A, Fitzpatrick PF, Halling P, Leyh TS, O'Donovan C, Raushel FM, Reschel U, Rohwer JM, Schnell S, Schomburg D, Tipton KF, Tsai MD, Westerhoff HV, Wittig U, Wohlgemuth R, Kettner C.

FEBS J. 2018 Mar 2. doi: 10.1111/febs.14427. [Epub ahead of print]

PMID:
29498804
4.

Gonadotropin-Releasing Hormone (GnRH) Neuron Excitability Is Regulated by Estradiol Feedback and Kisspeptin.

Adams C, Stroberg W, DeFazio RA, Schnell S, Moenter SM.

J Neurosci. 2018 Jan 31;38(5):1249-1263. doi: 10.1523/JNEUROSCI.2988-17.2017. Epub 2017 Dec 20.

PMID:
29263236
5.

1,2,3-Triazole Rings as a Disulfide Bond Mimetic in Chimeric AGRP-Melanocortin Peptides: Design, Synthesis, and Functional Characterization.

Tala SR, Singh A, Lensing CJ, Schnell SM, Freeman KT, Rocca JR, Haskell-Luevano C.

ACS Chem Neurosci. 2018 Jan 18. doi: 10.1021/acschemneuro.7b00422. [Epub ahead of print]

PMID:
29257879
6.

Plasticity of Signaling by Spinal Estrogen Receptor α, κ-Opioid Receptor, and Metabotropic Glutamate Receptors over the Rat Reproductive Cycle Regulates Spinal Endomorphin 2 Antinociception: Relevance of Endogenous-Biased Agonism.

Liu NJ, Murugaiyan V, Storman EM, Schnell SA, Kumar A, Wessendorf MW, Gintzler AR.

J Neurosci. 2017 Nov 15;37(46):11181-11191. doi: 10.1523/JNEUROSCI.1927-17.2017. Epub 2017 Oct 12.

PMID:
29025923
7.

Scalp Lesions in a Pediatric Patient with Hyper IgM Syndrome: Clinical and Histologic Mimicry of Cryptococcus neoformans Infection.

Acker KP, Fetch A, Schnell SA, Hammond J, Herrera C, Niedt G, Ratner AJ, Lauren CT.

J Pediatr. 2018 Jan;192:256-258. doi: 10.1016/j.jpeds.2017.08.065. Epub 2017 Sep 28.

PMID:
28965734
8.

Ancylobacter pratisalsi sp. nov. with plant growth promotion abilities from the rhizosphere of Plantago winteri Wirtg.

Suarez C, Ratering S, Schäfer J, Schnell S.

Int J Syst Evol Microbiol. 2017 Nov;67(11):4500-4506. doi: 10.1099/ijsem.0.002320. Epub 2017 Sep 25.

PMID:
28945527
9.

Voxel-by-voxel 4D flow MRI-based assessment of regional reverse flow in the aorta.

Shen X, Schnell S, Barker AJ, Suwa K, Tashakkor L, Jarvis K, Carr JC, Collins JD, Prabhakaran S, Markl M.

J Magn Reson Imaging. 2018 May;47(5):1276-1286. doi: 10.1002/jmri.25862. Epub 2017 Sep 18.

PMID:
28925047
10.

Estrogens synthesized and acting within a spinal oligomer suppress spinal endomorphin 2 antinociception: ebb and flow over the rat reproductive cycle.

Liu NJ, Murugaiyan V, Storman EM, Schnell SA, Wessendorf MW, Gintzler AR.

Pain. 2017 Oct;158(10):1903-1914. doi: 10.1097/j.pain.0000000000000991.

PMID:
28902684
12.

Microbiome analysis and confocal microscopy of used kitchen sponges reveal massive colonization by Acinetobacter, Moraxella and Chryseobacterium species.

Cardinale M, Kaiser D, Lueders T, Schnell S, Egert M.

Sci Rep. 2017 Jul 19;7(1):5791. doi: 10.1038/s41598-017-06055-9.

13.

Globalization and changing trends of biomedical research output.

Conte ML, Liu J, Schnell S, Omary MB.

JCI Insight. 2017 Jun 15;2(12). pii: 95206. doi: 10.1172/jci.insight.95206. [Epub ahead of print]

14.

JOURNAL CLUB: Four-Dimensional Flow MRI-Based Splenic Flow Index for Predicting Cirrhosis-Associated Hypersplenism.

Keller EJ, Kulik L, Stankovic Z, Lewandowski RJ, Salem R, Carr JC, Schnell S, Markl M, Collins JD.

AJR Am J Roentgenol. 2017 Jul;209(1):46-54. doi: 10.2214/AJR.16.17620. Epub 2017 May 2.

PMID:
28463524
15.

Inferring Intracellular Signal Transduction Circuitry from Molecular Perturbation Experiments.

Wynn ML, Egbert M, Consul N, Chang J, Wu ZF, Meravjer SD, Schnell S.

Bull Math Biol. 2017 Apr 28. doi: 10.1007/s11538-017-0270-9. [Epub ahead of print]

PMID:
28455685
16.

Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1-Arg-(pI)DPhe-Xaa4-NH2.

Doering SR, Freeman KT, Schnell SM, Haslach EM, Dirain M, Debevec G, Geer P, Santos RG, Giulianotti MA, Pinilla C, Appel JR, Speth RC, Houghten RA, Haskell-Luevano C.

J Med Chem. 2017 May 25;60(10):4342-4357. doi: 10.1021/acs.jmedchem.7b00301. Epub 2017 May 15.

PMID:
28453292
17.

On the origin of non-membrane-bound organelles, and their physiological function.

Stroberg W, Schnell S.

J Theor Biol. 2017 Dec 7;434:42-49. doi: 10.1016/j.jtbi.2017.04.006. Epub 2017 Apr 6.

PMID:
28392184
18.

Size and shape effects on the thermodynamic properties of nanoscale volumes of water.

Strøm BA, Simon JM, Schnell SK, Kjelstrup S, He J, Bedeaux D.

Phys Chem Chem Phys. 2017 Mar 29;19(13):9016-9027. doi: 10.1039/c7cp00874k.

PMID:
28304038
19.

Accelerated dual-venc 4D flow MRI for neurovascular applications.

Schnell S, Ansari SA, Wu C, Garcia J, Murphy IG, Rahman OA, Rahsepar AA, Aristova M, Collins JD, Carr JC, Markl M.

J Magn Reson Imaging. 2017 Jul;46(1):102-114. doi: 10.1002/jmri.25595. Epub 2017 Feb 2.

PMID:
28152256
20.

A Direct in Vivo Comparison of the Melanocortin Monovalent Agonist Ac-His-DPhe-Arg-Trp-NH2 versus the Bivalent Agonist Ac-His-DPhe-Arg-Trp-PEDG20-His-DPhe-Arg-Trp-NH2: A Bivalent Advantage.

Lensing CJ, Adank DN, Wilber SL, Freeman KT, Schnell SM, Speth RC, Zarth AT, Haskell-Luevano C.

ACS Chem Neurosci. 2017 Jun 21;8(6):1262-1278. doi: 10.1021/acschemneuro.6b00399. Epub 2017 Feb 16.

PMID:
28128928
21.

In Vivo Assessment of the Impact of Regional Intracranial Atherosclerotic Lesions on Brain Arterial 3D Hemodynamics.

Wu C, Schnell S, Vakil P, Honarmand AR, Ansari SA, Carr J, Markl M, Prabhakaran S.

AJNR Am J Neuroradiol. 2017 Mar;38(3):515-522. doi: 10.3174/ajnr.A5051. Epub 2017 Jan 5.

22.

A Macrocyclic Agouti-Related Protein/[Nle4,DPhe7]α-Melanocyte Stimulating Hormone Chimeric Scaffold Produces Subnanomolar Melanocortin Receptor Ligands.

Ericson MD, Freeman KT, Schnell SM, Haskell-Luevano C.

J Med Chem. 2017 Jan 26;60(2):805-813. doi: 10.1021/acs.jmedchem.6b01707. Epub 2017 Jan 17.

23.

The importance of accurately correcting for the natural abundance of stable isotopes.

Midani FS, Wynn ML, Schnell S.

Anal Biochem. 2017 Mar 1;520:27-43. doi: 10.1016/j.ab.2016.12.011. Epub 2017 Jan 11. Review.

24.

Superior Abdominal 4D Flow MRI Data Consistency with Adjusted Preprocessing Workflow and Noncontrast Acquisitions.

Keller EJ, Collins JD, Rigsby C, Carr JC, Markl M, Schnell S.

Acad Radiol. 2017 Mar;24(3):350-358. doi: 10.1016/j.acra.2016.10.007. Epub 2016 Dec 8.

PMID:
27940231
25.

Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity.

Udyavar AR, Wooten DJ, Hoeksema M, Bansal M, Califano A, Estrada L, Schnell S, Irish JM, Massion PP, Quaranta V.

Cancer Res. 2017 Mar 1;77(5):1063-1074. doi: 10.1158/0008-5472.CAN-16-1467. Epub 2016 Dec 8.

26.

Bacterial microbiota associated with flower pollen is influenced by pollination type, and shows a high degree of diversity and species-specificity.

Ambika Manirajan B, Ratering S, Rusch V, Schwiertz A, Geissler-Plaum R, Cardinale M, Schnell S.

Environ Microbiol. 2016 Dec;18(12):5161-5174. doi: 10.1111/1462-2920.13524. Epub 2016 Oct 24.

PMID:
27612299
27.

On the validity and errors of the pseudo-first-order kinetics in ligand-receptor binding.

Stroberg W, Schnell S.

Math Biosci. 2017 May;287:3-11. doi: 10.1016/j.mbs.2016.09.010. Epub 2016 Sep 28.

PMID:
27693063
28.

4D flow MRI demonstrates changes in cardiovascular haemodynamics in complex congenital heart disease.

Rose M, Rahman O, Schnell S, Robinson J, Rigsby C.

Eur Heart J Cardiovasc Imaging. 2017 Jan;18(1):114. doi: 10.1093/ehjci/jew204. Epub 2016 Sep 27. No abstract available.

PMID:
27679602
29.

On the estimation errors of KM and V from time-course experiments using the Michaelis-Menten equation.

Stroberg W, Schnell S.

Biophys Chem. 2016 Dec;219:17-27. doi: 10.1016/j.bpc.2016.09.004. Epub 2016 Sep 16.

PMID:
27677118
30.
31.

Approaches for the estimation of timescales in nonlinear dynamical systems: Timescale separation in enzyme kinetics as a case study.

Shoffner SK, Schnell S.

Math Biosci. 2017 May;287:122-129. doi: 10.1016/j.mbs.2016.09.001. Epub 2016 Sep 6. Review.

PMID:
27613486
32.

Complex Alterations of Intracranial 4-Dimensional Hemodynamics in Vein of Galen Aneurysmal Malformations During Staged Endovascular Embolization.

Wu C, Schoeneman SE, Kuhn R, Honarmand AR, Schnell S, Ansari SA, Carr J, Markl M, Shaibani A.

Oper Neurosurg (Hagerstown). 2016 Sep 1;12(3):239-249. doi: 10.1227/NEU.0000000000001137.

PMID:
29506111
33.

Coordination of signaling and tissue mechanics during morphogenesis of murine intestinal villi: a role for mitotic cell rounding.

Freddo AM, Shoffner SK, Shao Y, Taniguchi K, Grosse AS, Guysinger MN, Wang S, Rudraraju S, Margolis B, Garikipati K, Schnell S, Gumucio DL.

Integr Biol (Camb). 2016 Sep 12;8(9):918-28. doi: 10.1039/c6ib00046k. Epub 2016 Aug 1.

34.

Altered aortic shape in bicuspid aortic valve relatives influences blood flow patterns.

Schnell S, Smith DA, Barker AJ, Entezari P, Honarmand AR, Carr ML, Malaisrie SC, McCarthy PM, Collins J, Carr JC, Markl M.

Eur Heart J Cardiovasc Imaging. 2016 Nov;17(11):1239-1247. Epub 2016 Jul 26.

35.

Evaluation of blood flow distribution asymmetry and vascular geometry in patients with Fontan circulation using 4-D flow MRI.

Jarvis K, Schnell S, Barker AJ, Garcia J, Lorenz R, Rose M, Chowdhary V, Carr J, Robinson JD, Rigsby CK, Markl M.

Pediatr Radiol. 2016 Oct;46(11):1507-19. doi: 10.1007/s00247-016-3654-3. Epub 2016 Jun 27.

36.

A collection of intrinsic disorder characterizations from eukaryotic proteomes.

Vincent M, Schnell S.

Sci Data. 2016 Jun 21;3:160045. doi: 10.1038/sdata.2016.45.

37.

Four-dimensional MRI flow examinations in cerebral and extracerebral vessels - ready for clinical routine?

Schnell S, Wu C, Ansari SA.

Curr Opin Neurol. 2016 Aug;29(4):419-28. doi: 10.1097/WCO.0000000000000341. Review.

38.

Estimation of the lag time in a subsequent monomer addition model for fibril elongation.

Shoffner SK, Schnell S.

Phys Chem Chem Phys. 2016 Aug 3;18(31):21259-68. doi: 10.1039/c5cp07845h.

PMID:
27250246
39.

4D flow MR imaging of the portal venous system: a feasibility study in children.

Parekh K, Markl M, Rose M, Schnell S, Popescu A, Rigsby CK.

Eur Radiol. 2017 Feb;27(2):832-840. doi: 10.1007/s00330-016-4396-1. Epub 2016 May 18.

PMID:
27193778
40.

Efficient method for volumetric assessment of peak blood flow velocity using 4D flow MRI.

Rose MJ, Jarvis K, Chowdhary V, Barker AJ, Allen BD, Robinson JD, Markl M, Rigsby CK, Schnell S.

J Magn Reson Imaging. 2016 Dec;44(6):1673-1682. doi: 10.1002/jmri.25305. Epub 2016 May 18.

41.

Rethinking Models of Pattern Formation in Somitogenesis.

Maini PK, Baker RE, Schnell S.

Cell Syst. 2015 Oct 28;1(4):248-9. doi: 10.1016/j.cels.2015.10.004. Epub 2015 Oct 28.

42.

RhoC GTPase Is a Potent Regulator of Glutamine Metabolism and N-Acetylaspartate Production in Inflammatory Breast Cancer Cells.

Wynn ML, Yates JA, Evans CR, Van Wassenhove LD, Wu ZF, Bridges S, Bao L, Fournier C, Ashrafzadeh S, Merrins MJ, Satin LS, Schnell S, Burant CF, Merajver SD.

J Biol Chem. 2016 Jun 24;291(26):13715-29. doi: 10.1074/jbc.M115.703959. Epub 2016 Apr 25.

43.

Quantitative proteome-based guidelines for intrinsic disorder characterization.

Vincent M, Whidden M, Schnell S.

Biophys Chem. 2016 Jun;213:6-16. doi: 10.1016/j.bpc.2016.03.005. Epub 2016 Apr 5.

PMID:
27085142
44.

Analyzing myocardial torsion based on tissue phase mapping cardiovascular magnetic resonance.

Chitiboi T, Schnell S, Collins J, Carr J, Chowdhary V, Honarmand AR, Hennemuth A, Linsen L, Hahn HK, Markl M.

J Cardiovasc Magn Reson. 2016 Apr 10;18:15. doi: 10.1186/s12968-016-0234-5.

45.

An in Vitro and in Vivo Investigation of Bivalent Ligands That Display Preferential Binding and Functional Activity for Different Melanocortin Receptor Homodimers.

Lensing CJ, Freeman KT, Schnell SM, Adank DN, Speth RC, Haskell-Luevano C.

J Med Chem. 2016 Apr 14;59(7):3112-28. doi: 10.1021/acs.jmedchem.5b01894. Epub 2016 Mar 29.

46.

Advanced flow MRI: emerging techniques and applications.

Markl M, Schnell S, Wu C, Bollache E, Jarvis K, Barker AJ, Robinson JD, Rigsby CK.

Clin Radiol. 2016 Aug;71(8):779-95. doi: 10.1016/j.crad.2016.01.011. Epub 2016 Mar 2. Review.

47.

Procedures for the reconstruction, primary culture and experimental use of rainbow trout gill epithelia.

Schnell S, Stott LC, Hogstrand C, Wood CM, Kelly SP, Pärt P, Owen SF, Bury NR.

Nat Protoc. 2016 Mar;11(3):490-8. doi: 10.1038/nprot.2016.029. Epub 2016 Feb 11.

PMID:
26866792
48.

A computational approach to studying ageing at the individual level.

Harvanek ZM, Mourão MA, Schnell S, Pletcher SD.

Proc Biol Sci. 2016 Feb 10;283(1824). pii: 20152346. doi: 10.1098/rspb.2015.2346.

49.

Towards high-resolution 4D flow MRI in the human aorta using kt-GRAPPA and B1+ shimming at 7T.

Schmitter S, Schnell S, Uğurbil K, Markl M, Van de Moortele PF.

J Magn Reson Imaging. 2016 Aug;44(2):486-99. doi: 10.1002/jmri.25164. Epub 2016 Feb 3.

50.

Age-Related Changes of Normal Cerebral and Cardiac Blood Flow in Children and Adults Aged 7 Months to 61 Years.

Wu C, Honarmand AR, Schnell S, Kuhn R, Schoeneman SE, Ansari SA, Carr J, Markl M, Shaibani A.

J Am Heart Assoc. 2016 Jan 4;5(1). pii: e002657. doi: 10.1161/JAHA.115.002657.

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