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[Update of the S2k guidelines : Surgical treatment of benign thyroid diseases].

Musholt TJ, Bockisch A, Clerici T, Dotzenrath C, Dralle H, Goretzki PE, Hermann M, Holzer K, Karges W, Krude H, Kussmann J, Lorenz K, Luster M, Niederle B, Nies C, Riss P, Schabram J, Schabram P, Schmid KW, Simon D, Spitzweg C, Steinmüller T, Trupka A, Vorländer C, Weber T, Bartsch DK; Leitliniengruppe der CAEK.

Chirurg. 2018 Jun 6. doi: 10.1007/s00104-018-0653-y. [Epub ahead of print] Review. German.


Immunohistochemically detectable metallothionein expression in malignant pleural mesotheliomas is strongly associated with early failure to platin-based chemotherapy.

Mairinger FD, Schmeller J, Borchert S, Wessolly M, Mairinger E, Kollmeier J, Hager T, Mairinger T, Christoph DC, Walter RFH, Eberhardt WEE, Plönes T, Wohlschlaeger J, Jasani B, Schmid KW, Bankfalvi A.

Oncotarget. 2018 Apr 27;9(32):22254-22268. doi: 10.18632/oncotarget.24962. eCollection 2018 Apr 27.


Methylation of L1RE1, RARB, and RASSF1 function as possible biomarkers for the differential diagnosis of lung cancer.

Walter RFH, Rozynek P, Casjens S, Werner R, Mairinger FD, Speel EJM, Zur Hausen A, Meier S, Wohlschlaeger J, Theegarten D, Behrens T, Schmid KW, Brüning T, Johnen G.

PLoS One. 2018 May 31;13(5):e0195716. doi: 10.1371/journal.pone.0195716. eCollection 2018.


Papilloma of the Fallopian Tube: A Rare Gynecologic Neoplasm Harboring a BRAF (c.1799T>A) Mutation (V600E).

Wohlschlaeger J, Davidson B, Worm K, Feist H, Peters J, Hager T, Schmid KW, Ostertag H.

Int J Gynecol Pathol. 2018 May 30. doi: 10.1097/PGP.0000000000000526. [Epub ahead of print]


Pathogenic and targetable genetic alterations in 70 urachal adenocarcinomas.

Reis H, van der Vos KE, Niedworok C, Herold T, Módos O, Szendrői A, Hager T, Ingenwerth M, Vis DJ, Behrendt MA, de Jong J, van der Heijden MS, Peyronnet B, Mathieu R, Wiesweg M, Ablat J, Okon K, Tolkach Y, Keresztes D, Nagy N, Bremmer F, Gaisa NT, Chlosta P, Kriegsmann J, Kovalszky I, Timar J, Kristiansen G, Radzun HJ, Knüchel R, Schuler M, Black PC, Rübben H, Hadaschik BA, Schmid KW, van Rhijn BWG, Nyirády P, Szarvas T.

Int J Cancer. 2018 Apr 19. doi: 10.1002/ijc.31547. [Epub ahead of print]


MET Expression in Advanced Non-Small-Cell Lung Cancer: Effect on Clinical Outcomes of Chemotherapy, Targeted Therapy, and Immunotherapy.

Reis H, Metzenmacher M, Goetz M, Savvidou N, Darwiche K, Aigner C, Herold T, Eberhardt WE, Skiba C, Hense J, Virchow I, Westerwick D, Bogner S, Ting S, Kasper S, Stuschke M, Nensa F, Herrmann K, Hager T, Schmid KW, Schuler M, Wiesweg M.

Clin Lung Cancer. 2018 Mar 17. pii: S1525-7304(18)30052-4. doi: 10.1016/j.cllc.2018.03.010. [Epub ahead of print]


Phosphorylation of p70 Ribosomal Protein S6 Kinase β-1 is an Independent Prognostic Parameter in Metastatic Colorectal Cancer.

Wiesweg M, Reis H, Köster T, Goetz M, Worm K, Herold T, Paul A, Dechêne A, Schumacher B, Markus P, Virchow I, Kostbade K, Wolf N, Zaun G, Metzenmacher M, Schmid KW, Schuler M, Kasper S.

Clin Colorectal Cancer. 2018 Jun;17(2):e331-e352. doi: 10.1016/j.clcc.2018.02.003. Epub 2018 Feb 17.


Proposal for an extended pTNM classification of thyroid carcinoma : Commentary on deficits of the 8th edition of the TNM classification.

Schmid KW, Synoracki S, Dralle H, Wittekind C.

Pathologe. 2018 Feb 19. doi: 10.1007/s00292-018-0418-x. [Epub ahead of print] Review.


[Proposal for an extended pTNM classification of thyroid carcinoma : Commentary on deficits of the 8th edition of the TNM classification (German version)].

Schmid KW, Synoracki S, Dralle H, Wittekind C.

Pathologe. 2018 Feb;39(1):49-56. doi: 10.1007/s00292-017-0410-x. Review. German.


Max Schottelius: Pioneer in Pheochromocytoma.

Bausch B, Tischler AS, Schmid KW, Leijon H, Eng C, Neumann HPH.

J Endocr Soc. 2017 Jul 1;1(7):957-964. doi: 10.1210/js.2017-00208. eCollection 2017 Jul 1. Review.


[Lysosomal acid lipase deficiency (LAL-D) : Diagnostic and therapeutic options in an underdiagnosed disease].

Synoracki S, Kathemann S, Schmid KW, Jastrow H, Baba HA.

Pathologe. 2018 May;39(3):249-254. doi: 10.1007/s00292-017-0400-z. Review. German.


Cytomegalovirus reactivation in patients with refractory checkpoint inhibitor-induced colitis.

Franklin C, Rooms I, Fiedler M, Reis H, Milsch L, Herz S, Livingstone E, Zimmer L, Schmid KW, Dittmer U, Schadendorf D, Schilling B.

Eur J Cancer. 2017 Nov;86:248-256. doi: 10.1016/j.ejca.2017.09.019. Epub 2017 Oct 19.


[Retinoblastoma and retinocytoma (retinoma)].

Metz KA, Westerwick D, Driever F, Schmid KW, Le Guin CHD.

Pathologe. 2017 Nov;38(6):507-514. doi: 10.1007/s00292-017-0384-8. Review. German.


[Intraocular metastases].

Westerwick D, Driever F, Le Guin CHD, Schmid KW, Metz KA.

Pathologe. 2017 Nov;38(6):500-506. doi: 10.1007/s00292-017-0373-y. Review. German.


[Molecular Pathogenesis of Thyroid Nodules: Relevance for Clinical Care].

Führer D, Musholt T, Schmid KW.

Laryngorhinootologie. 2017 Sep;96(9):590-596. doi: 10.1055/s-0043-109180. Epub 2017 Sep 7. German.


[Definition of R1 resection in thyroid carcinoma].

Synoracki S, Wittekind C, Dralle H, Schmid KW.

Chirurg. 2017 Sep;88(9):740-747. doi: 10.1007/s00104-017-0461-9. Review. German.


Comprehensive Biomarker Analyses in Patients with Advanced or Metastatic Non-Small Cell Lung Cancer Prospectively Treated with the Polo-Like Kinase 1 Inhibitor BI2536.

Breitenbuecher F, von Pawel J, Sebastian M, Kortsik C, Ting S, Kasper S, Wohlschläger J, Worm K, Morresi-Hauf A, Schad A, Westerwick D, Wehler B, Werner M, Munzert G, Gaschler-Markefski B, Schmid KW, Schuler M.

Oncol Res Treat. 2017;40(7-8):435-439. doi: 10.1159/000475503. Epub 2017 Jun 20.


Differential regulation of monocarboxylate transporter 8 expression in thyroid cancer and hyperthyroidism.

Badziong J, Ting S, Synoracki S, Tiedje V, Brix K, Brabant G, Moeller LC, Schmid KW, Fuhrer D, Zwanziger D.

Eur J Endocrinol. 2017 Sep;177(3):243-250. doi: 10.1530/EJE-17-0279. Epub 2017 Jun 2.


Molecular dissection of effector mechanisms of RAS-mediated resistance to anti-EGFR antibody therapy.

Kasper S, Reis H, Ziegler S, Nothdurft S, Mueller A, Goetz M, Wiesweg M, Phasue J, Ting S, Wieczorek S, Even A, Worm K, Pogorzelski M, Breitenbuecher S, Meiler J, Paul A, Trarbach T, Schmid KW, Breitenbuecher F, Schuler M.

Oncotarget. 2017 Jul 11;8(28):45898-45917. doi: 10.18632/oncotarget.17438.


NGS based identification of mutational hotspots for targeted therapy in anaplastic thyroid carcinoma.

Tiedje V, Ting S, Herold T, Synoracki S, Latteyer S, Moeller LC, Zwanziger D, Stuschke M, Fuehrer D, Schmid KW.

Oncotarget. 2017 Jun 27;8(26):42613-42620. doi: 10.18632/oncotarget.17300.


miRNA regulation is important for DNA damage repair and recognition in malignant pleural mesothelioma.

Mairinger FD, Werner R, Flom E, Schmeller J, Borchert S, Wessolly M, Wohlschlaeger J, Hager T, Mairinger T, Kollmeier J, Christoph DC, Schmid KW, Walter RFH.

Virchows Arch. 2017 Jun;470(6):627-637. doi: 10.1007/s00428-017-2133-z. Epub 2017 May 2.


Erratum to: Curcumin induces G2/M arrest, apoptosis, NF-κB inhibition, and expression of differentiation genes in thyroid carcinoma cells.

Schwertheim S, Wein F, Lennartz K, Worm K, Schmid KW, Sheu-Grabellus SY.

J Cancer Res Clin Oncol. 2017 Jul;143(7):1155-1156. doi: 10.1007/s00432-017-2403-9. No abstract available.


Impact of BCL2 polymorphisms on survival in transitional cell carcinoma of the bladder.

Hess J, Stelmach P, Eisenhardt A, Rübben H, Reis H, Schmid KW, Bachmann HS.

J Cancer Res Clin Oncol. 2017 Sep;143(9):1659-1670. doi: 10.1007/s00432-017-2404-8. Epub 2017 Apr 17.


Folic acid phenotype (FAP) is a superior biomarker predicting response to pemetrexed-based chemotherapy in malignant pleural mesothelioma.

Mairinger FD, Vollbrecht C, Flom E, Christoph DC, Schmid KW, Kollmeier J, Popper HH, Mairinger T, Walter RFH.

Oncotarget. 2017 Jun 6;8(23):37502-37510. doi: 10.18632/oncotarget.16398.


Curcumin induces G2/M arrest, apoptosis, NF-κB inhibition, and expression of differentiation genes in thyroid carcinoma cells.

Schwertheim S, Wein F, Lennartz K, Worm K, Schmid KW, Sheu-Grabellus SY.

J Cancer Res Clin Oncol. 2017 Jul;143(7):1143-1154. doi: 10.1007/s00432-017-2380-z. Epub 2017 Mar 6. Erratum in: J Cancer Res Clin Oncol. 2017 Jul;143(7):1155-1156.


[The Olympic motto of pathology].

Schmid KW.

Pathologe. 2017 Feb;38(1):1-2. doi: 10.1007/s00292-017-0267-z. German. No abstract available.


ACTB, CDKN1B, GAPDH, GRB2, RHOA and SDCBP Were Identified as Reference Genes in Neuroendocrine Lung Cancer via the nCounter Technology.

Walter RF, Werner R, Vollbrecht C, Hager T, Flom E, Christoph DC, Schmeller J, Schmid KW, Wohlschlaeger J, Mairinger FD.

PLoS One. 2016 Nov 1;11(11):e0165181. doi: 10.1371/journal.pone.0165181. eCollection 2016.


Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy.

Walter RF, Vollbrecht C, Werner R, Mairinger T, Schmeller J, Flom E, Wohlschlaeger J, Barbetakis N, Paliouras D, Chatzinikolaou F, Adamidis V, Tsakiridis K, Zarogoulidis P, Trakada G, Christoph DC, Schmid KW, Mairinger FD.

J Cancer. 2016 Sep 13;7(13):1915-1925. eCollection 2016.


Targeted next-generation sequencing for TP53, RAS, BRAF, ALK and NF1 mutations in anaplastic thyroid cancer.

Latteyer S, Tiedje V, König K, Ting S, Heukamp LC, Meder L, Schmid KW, Führer D, Moeller LC.

Endocrine. 2016 Dec;54(3):733-741. doi: 10.1007/s12020-016-1080-9. Epub 2016 Oct 1.


High Prevalence of Concomitant Oncogene Mutations in Prospectively Identified Patients with ROS1-Positive Metastatic Lung Cancer.

Wiesweg M, Eberhardt WEE, Reis H, Ting S, Savvidou N, Skiba C, Herold T, Christoph DC, Meiler J, Worm K, Kasper S, Theegarten D, Hense J, Hager T, Darwiche K, Oezkan F, Aigner C, Welter S, Kühl H, Stuschke M, Schmid KW, Schuler M.

J Thorac Oncol. 2017 Jan;12(1):54-64. doi: 10.1016/j.jtho.2016.08.137. Epub 2016 Aug 27.


Prognostic relevance of caspase 8 -652 6N InsDel and Asp302His polymorphisms for breast cancer.

Kuhlmann JD, Bankfalvi A, Schmid KW, Callies R, Kimmig R, Wimberger P, Siffert W, Bachmann HS.

BMC Cancer. 2016 Aug 9;16:618. doi: 10.1186/s12885-016-2662-x.


Prognostic relevance of autophagy-related markers LC3, p62/sequestosome 1, Beclin-1 and ULK1 in colorectal cancer patients with respect to KRAS mutational status.

Schmitz KJ, Ademi C, Bertram S, Schmid KW, Baba HA.

World J Surg Oncol. 2016 Jul 22;14(1):189. doi: 10.1186/s12957-016-0946-x.


Intermediate microRNA expression profile in Graves' disease falls between that of normal thyroid tissue and papillary thyroid carcinoma.

Pohl M, Grabellus F, Worm K, Arnold G, Walz M, Schmid KW, Sheu-Grabellus SY.

J Clin Pathol. 2017 Jan;70(1):33-39. doi: 10.1136/jclinpath-2016-203739. Epub 2016 Jul 1.


Prognostic markers and response to vandetanib therapy in sporadic medullary thyroid cancer patients.

Tiedje V, Ting S, Walter RF, Herold T, Worm K, Badziong J, Zwanziger D, Schmid KW, Führer D.

Eur J Endocrinol. 2016 Sep;175(3):173-80. doi: 10.1530/EJE-16-0252. Epub 2016 Jun 9.


MiR-205 and MiR-373 Are Associated with Aggressive Human Mucinous Colorectal Cancer.

Eyking A, Reis H, Frank M, Gerken G, Schmid KW, Cario E.

PLoS One. 2016 Jun 6;11(6):e0156871. doi: 10.1371/journal.pone.0156871. eCollection 2016.


[Inflammatory diseases of the thyroid gland].

Synoracki S, Ting S, Schmid KW.

Pathologe. 2016 May;37(3):215-23. doi: 10.1007/s00292-016-0157-9. Review. German.


[Inflammation of the parathyroid glands].

Ting S, Synoracki S, Sheu SY, Schmid KW.

Pathologe. 2016 May;37(3):224-9. doi: 10.1007/s00292-016-0155-y. Review. German.


Folic-acid metabolism and DNA-repair phenotypes differ between neuroendocrine lung tumors and associate with aggressive subtypes, therapy resistance and outcome.

Walter RF, Mairinger FD, Werner R, Vollbrecht C, Hager T, Schmid KW, Wohlschlaeger J, Christoph DC.

Oncotarget. 2016 Apr 12;7(15):20166-79. doi: 10.18632/oncotarget.7737.


Soluble syndecan-1 (SDC1) serum level as an independent pre-operative predictor of cancer-specific survival in prostate cancer.

Szarvas T, Reis H, Vom Dorp F, Tschirdewahn S, Niedworok C, Nyirady P, Schmid KW, Rübben H, Kovalszky I.

Prostate. 2016 Aug;76(11):977-85. doi: 10.1002/pros.23186. Epub 2016 Apr 7.


Pediatric Differentiated Thyroid Carcinoma in The Netherlands: A Nationwide Follow-Up Study.

Klein Hesselink MS, Nies M, Bocca G, Brouwers AH, Burgerhof JG, van Dam EW, Havekes B, van den Heuvel-Eibrink MM, Corssmit EP, Kremer LC, Netea-Maier RT, van der Pal HJ, Peeters RP, Schmid KW, Smit JW, Williams GR, Plukker JT, Ronckers CM, van Santen HM, Tissing WJ, Links TP.

J Clin Endocrinol Metab. 2016 May;101(5):2031-9. doi: 10.1210/jc.2015-3290. Epub 2016 Mar 10.


microRNAs are differentially regulated between MDM2-positive and negative malignant pleural mesothelioma.

Walter RF, Vollbrecht C, Werner R, Wohlschlaeger J, Christoph DC, Schmid KW, Mairinger FD.

Oncotarget. 2016 Apr 5;7(14):18713-21. doi: 10.18632/oncotarget.7666.


A 6-Base Pair in Frame Germline Deletion in Exon 7 Of RET Leads to Increased RET Phosphorylation, ERK Activation, and MEN2A.

Latteyer S, Klein-Hitpass L, Khandanpour C, Zwanziger D, Poeppel TD, Schmid KW, Führer D, Moeller LC.

J Clin Endocrinol Metab. 2016 Mar;101(3):1016-22. doi: 10.1210/jc.2015-2948. Epub 2016 Jan 14.


Mutational analysis of pulmonary tumours with neuroendocrine features using targeted massive parallel sequencing: a comparison of a neglected tumour group.

Vollbrecht C, Werner R, Walter RF, Christoph DC, Heukamp LC, Peifer M, Hirsch B, Burbat L, Mairinger T, Schmid KW, Wohlschlaeger J, Mairinger FD.

Br J Cancer. 2015 Dec 22;113(12):1704-11. doi: 10.1038/bjc.2015.397. Epub 2015 Dec 8.


Histopathology of C Cells and Medullary Thyroid Carcinoma.

Schmid KW.

Recent Results Cancer Res. 2015;204:41-60. doi: 10.1007/978-3-319-22542-5_2. Review.


[Clinical importance of thyroid gland cytology].

Ting S, Synoracki S, Bockisch A, Führer D, Schmid KW.

Pathologe. 2015 Nov;36(6):543-52. Review. German.


[Lymph node and distant metastases of thyroid gland cancer. Metastases in the thyroid glands].

Schmid KW.

Pathologe. 2015 Nov;36 Suppl 2:171-5. doi: 10.1007/s00292-015-0071-6. Review. German.


[Medullary thyroid carcinoma].

Tiedje V, Ting S, Dralle H, Schmid KW, Führer D.

Internist (Berl). 2015 Sep;56(9):1019-31. doi: 10.1007/s00108-014-3638-z. German.


The impact of CLAUDIN-1 on follicular thyroid carcinoma aggressiveness.

Zwanziger D, Badziong J, Ting S, Moeller LC, Schmid KW, Siebolts U, Wickenhauser C, Dralle H, Fuehrer D.

Endocr Relat Cancer. 2015 Oct;22(5):819-30. doi: 10.1530/ERC-14-0502. Epub 2015 Jul 28.


Risk and timing of biochemical recurrence in pT3aN0/Nx prostate cancer with positive surgical margin - A multicenter study.

Karl A, Buchner A, Tympner C, Kirchner T, Ganswindt U, Belka C, Ganzer R, Wieland W, Eder F, Hofstädter F, Schilling D, Sievert KD, Stenzl A, Scharpf M, Fend F, Vom Dorp F, Rübben H, Schmid KW, Porres-Knoblauch D, Heidenreich A, Hangarter B, Knüchel-Clarke R, Rogenhofer M, Wullich B, Hartmann A, Comploj E, Pycha A, Hanspeter E, Pehrke D, Sauter G, Graefen M, Gratzke C, Stief C, Wiegel T, Haese A.

Radiother Oncol. 2015 Jul;116(1):119-24. doi: 10.1016/j.radonc.2015.06.021. Epub 2015 Jun 29.


AQP1, AQP5, Bcl-2 and p16 in pharyngeal squamous cell carcinoma.

Lehnerdt GF, Bachmann HS, Adamzik M, Panic A, Köksal E, Weller P, Lang S, Schmid KW, Siffert W, Bankfalvi A.

J Laryngol Otol. 2015 Jun;129(6):580-6. doi: 10.1017/S002221511500119X.


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