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Items: 1 to 50 of 197

1.

Nanomaterials in the Environment: Behavior, Fate, Bioavailability, and Effects-An Updated Review.

Lead JR, Batley GE, Alvarez PJJ, Croteau MN, Handy RD, McLaughlin MJ, Judy JD, Schirmer K.

Environ Toxicol Chem. 2018 Apr 6. doi: 10.1002/etc.4147. [Epub ahead of print] Review.

PMID:
29633323
2.

Biotransformation of Benzo[ a]pyrene by Three Rainbow Trout ( Onchorhynchus mykiss) Cell Lines and Extrapolation To Derive a Fish Bioconcentration Factor.

Stadnicka-Michalak J, Weiss FT, Fischer M, Tanneberger K, Schirmer K.

Environ Sci Technol. 2018 Mar 6;52(5):3091-3100. doi: 10.1021/acs.est.7b04548. Epub 2018 Feb 22.

PMID:
29400055
3.

Glutathione S-Transferase Protein Expression in Different Life Stages of Zebrafish (Danio rerio).

Tierbach A, Groh KJ, Schönenberger R, Schirmer K, Suter MJ.

Toxicol Sci. 2018 Apr 1;162(2):702-712. doi: 10.1093/toxsci/kfx293.

4.

A validated algorithm for selecting non-toxic chemical concentrations.

Stadnicka-Michalak J, Knöbel M, Županič A, Schirmer K.

ALTEX. 2018;35(1):37-50. doi: 10.14573/altex.1701231. Epub 2017 Jun 26.

5.

European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters.

Tousova Z, Oswald P, Slobodnik J, Blaha L, Muz M, Hu M, Brack W, Krauss M, Di Paolo C, Tarcai Z, Seiler TB, Hollert H, Koprivica S, Ahel M, Schollée JE, Hollender J, Suter MJ, Hidasi AO, Schirmer K, Sonavane M, Ait-Aissa S, Creusot N, Brion F, Froment J, Almeida AC, Thomas K, Tollefsen KE, Tufi S, Ouyang X, Leonards P, Lamoree M, Torrens VO, Kolkman A, Schriks M, Spirhanzlova P, Tindall A, Schulze T.

Sci Total Environ. 2017 Dec 1;601-602:1849-1868. doi: 10.1016/j.scitotenv.2017.06.032. Epub 2017 Jun 15.

PMID:
28629112
6.

A fish intestinal epithelial barrier model established from the rainbow trout (Oncorhynchus mykiss) cell line, RTgutGC.

Minghetti M, Drieschner C, Bramaz N, Schug H, Schirmer K.

Cell Biol Toxicol. 2017 Dec;33(6):539-555. doi: 10.1007/s10565-017-9385-x. Epub 2017 Mar 1.

7.

Interaction of silver nanoparticles with algae and fish cells: a side by side comparison.

Yue Y, Li X, Sigg L, Suter MJ, Pillai S, Behra R, Schirmer K.

J Nanobiotechnology. 2017 Feb 28;15(1):16. doi: 10.1186/s12951-017-0254-9.

8.

Ultrathin Alumina Membranes as Scaffold for Epithelial Cell Culture from the Intestine of Rainbow Trout.

Drieschner C, Minghetti M, Wu S, Renaud P, Schirmer K.

ACS Appl Mater Interfaces. 2017 Mar 22;9(11):9496-9505. doi: 10.1021/acsami.7b00705. Epub 2017 Mar 9.

PMID:
28244327
9.

Cell culture-based biosensing techniques for detecting toxicity in water.

Tan L, Schirmer K.

Curr Opin Biotechnol. 2017 Jun;45:59-68. doi: 10.1016/j.copbio.2016.11.026. Epub 2017 Jan 27. Review.

10.

Dose-dependent effects of morphine on lipopolysaccharide (LPS)-induced inflammation, and involvement of multixenobiotic resistance (MXR) transporters in LPS efflux in teleost fish.

Mottaz H, Schönenberger R, Fischer S, Eggen RIL, Schirmer K, Groh KJ.

Environ Pollut. 2017 Feb;221:105-115. doi: 10.1016/j.envpol.2016.11.046. Epub 2016 Dec 20.

PMID:
28010888
11.

Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and research priorities.

Armitage JM, Erickson RJ, Luckenbach T, Ng CA, Prosser RS, Arnot JA, Schirmer K, Nichols JW.

Environ Toxicol Chem. 2017 Apr;36(4):882-897. doi: 10.1002/etc.3680. Epub 2016 Dec 19. Review.

PMID:
27992066
12.

Clobetasol propionate causes immunosuppression in zebrafish (Danio rerio) at environmentally relevant concentrations.

Hidasi AO, Groh KJ, Suter MJ, Schirmer K.

Ecotoxicol Environ Saf. 2017 Apr;138:16-24. doi: 10.1016/j.ecoenv.2016.11.024. Epub 2016 Dec 22.

PMID:
27987419
13.

From the Cover: Zebrafish Larvae Are Insensitive to Stimulation by Cocaine: Importance of Exposure Route and Toxicokinetics.

Kirla KT, Groh KJ, Steuer AE, Poetzsch M, Banote RK, Stadnicka-Michalak J, Eggen RI, Schirmer K, Kraemer T.

Toxicol Sci. 2016 Nov;154(1):183-193. Epub 2016 Aug 11.

PMID:
27521082
14.

Alternative approaches to vertebrate ecotoxicity tests in the 21st century: A review of developments over the last 2 decades and current status.

Lillicrap A, Belanger S, Burden N, Pasquier DD, Embry MR, Halder M, Lampi MA, Lee L, Norberg-King T, Rattner BA, Schirmer K, Thomas P.

Environ Toxicol Chem. 2016 Nov;35(11):2637-2646. doi: 10.1002/etc.3603. Review.

PMID:
27779828
15.

Effect of media composition on bioavailability and toxicity of silver and silver nanoparticles in fish intestinal cells (RTgutGC).

Minghetti M, Schirmer K.

Nanotoxicology. 2016 Dec;10(10):1526-1534. Epub 2016 Oct 21.

PMID:
27689691
16.

Contribution of hepatic cytochrome CYP1A and metallothionein mRNA abundance to biomonitoring-A case study with European flounder (Platichthys flesus) from the Gulf of Gdańsk.

Kopecka-Pilarczyk J, Schirmer K.

Comp Biochem Physiol C Toxicol Pharmacol. 2016 Oct;188:24-9. doi: 10.1016/j.cbpc.2016.06.001. Epub 2016 Jun 5.

PMID:
27276230
17.

Cell compatible encapsulation of filaments into 3D hydrogels.

Schirmer KS, Gorkin R 3rd, Beirne S, Stewart E, Thompson BC, Quigley AF, Kapsa RM, Wallace GG.

Biofabrication. 2016 May 23;8(2):025013. doi: 10.1088/1758-5090/8/2/025013.

PMID:
27213861
18.

Erratum to: LC-MS/MS determination of potential endocrine disruptors of cortico signalling in rivers and wastewaters.

Ammann AA, Macikova P, Groh KJ, Schirmer K, Suter MJ.

Anal Bioanal Chem. 2016 Jul;408(17):4821-4822. Epub 2016 Apr 26. No abstract available.

PMID:
27116420
19.

Silver nanoparticles inhibit fish gill cell proliferation in protein-free culture medium.

Yue Y, Behra R, Sigg L, Schirmer K.

Nanotoxicology. 2016 Oct;10(8):1075-83. doi: 10.3109/17435390.2016.1172677. Epub 2016 Apr 21.

PMID:
27030289
20.

Transformation of Contaminant Candidate List (CCL3) compounds during ozonation and advanced oxidation processes in drinking water: Assessment of biological effects.

Mestankova H, Parker AM, Bramaz N, Canonica S, Schirmer K, von Gunten U, Linden KG.

Water Res. 2016 Apr 15;93:110-120. doi: 10.1016/j.watres.2015.12.048. Epub 2016 Jan 21.

PMID:
26900972
21.

An interlaboratory comparison of nanosilver characterisation and hazard identification: Harmonising techniques for high quality data.

Jemec A, Kahru A, Potthoff A, Drobne D, Heinlaan M, Böhme S, Geppert M, Novak S, Schirmer K, Rekulapally R, Singh S, Aruoja V, Sihtmäe M, Juganson K, Käkinen A, Kühnel D.

Environ Int. 2016 Feb;87:20-32. doi: 10.1016/j.envint.2015.10.014. Epub 2015 Nov 28.

22.

Toxicology across scales: Cell population growth in vitro predicts reduced fish growth.

Stadnicka-Michalak J, Schirmer K, Ashauer R.

Sci Adv. 2015 Aug 7;1(7):e1500302. doi: 10.1126/sciadv.1500302. eCollection 2015 Aug.

23.

Early life exposure to PCB126 results in delayed mortality and growth impairment in the zebrafish larvae.

Di Paolo C, Groh KJ, Zennegg M, Vermeirssen EL, Murk AJ, Eggen RI, Hollert H, Werner I, Schirmer K.

Aquat Toxicol. 2015 Dec;169:168-78. doi: 10.1016/j.aquatox.2015.10.014. Epub 2015 Oct 28.

PMID:
26551687
24.

Chemical Aspects of Nanoparticle Ecotoxicology.

Sigg L, Behra R, Groh K, Isaacson C, Odzak N, Piccapietra F, Röhder L, Schug H, Yue Y, Schirmer K.

Chimia (Aarau). 2014 Nov;68(11):806-11. doi: 10.2533/chimia.2014.806.

PMID:
26508489
25.

Scientific Basis for Regulatory Decision-Making of Nanomaterials Report on the Workshop, 20-21 January 2014, Center of Applied Ecotoxicology, Dübendorf.

Studer C, Aicher L, Gasic B, von Goetz N, Hoet P, Huwyler J, Kägi R, Kase R, Kobe A, Nowack B, Rothen-Rutishauser B, Schirmer K, Schneider G, Vermeissen E, Wick P, Walser T.

Chimia (Aarau). 2015;69(1-2):52-6. doi: 10.2533/chimia.2015.52.

PMID:
26507088
26.

In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells.

Ramachandran SD, Schirmer K, Münst B, Heinz S, Ghafoory S, Wölfl S, Simon-Keller K, Marx A, Øie CI, Ebert MP, Walles H, Braspenning J, Breitkopf-Heinlein K.

PLoS One. 2015 Oct 21;10(10):e0139345. doi: 10.1371/journal.pone.0139345. eCollection 2015.

27.

Establishment of the first humpback whale fibroblast cell lines and their application in chemical risk assessment.

Burkard M, Whitworth D, Schirmer K, Nash SB.

Aquat Toxicol. 2015 Oct;167:240-7. doi: 10.1016/j.aquatox.2015.08.005. Epub 2015 Aug 20.

PMID:
26363275
28.

Novel test procedure to evaluate the treatability of wastewater with ozone.

Schindler Wildhaber Y, Mestankova H, Schärer M, Schirmer K, Salhi E, von Gunten U.

Water Res. 2015 May 15;75:324-35. doi: 10.1016/j.watres.2015.02.030. Epub 2015 Feb 25.

PMID:
25827671
29.

Octopamine regulates antennal sensory neurons via daytime-dependent changes in cAMP and IP3 levels in the hawkmoth Manduca sexta.

Schendzielorz T, Schirmer K, Stolte P, Stengl M.

PLoS One. 2015 Mar 18;10(3):e0121230. doi: 10.1371/journal.pone.0121230. eCollection 2015.

30.

Scientific Basis for Regulatory Decision-Making of Nanomaterials Report on the Workshop, 20-21 January 2014, Center of Applied Ecotoxicology, Dübendorf.

Studer C, Aicher L, Gasic B, von Goetz N, Hoet P, Huwyler J, Kägi R, Kase R, Kobe A, Nowack B, Rothen-Rutishauser B, Schirmer K, Schneider G, Vermeissen E, Wick P, Walser T.

Chimia (Aarau). 2015 Feb 25;69(1):52-56. doi: 10.2533/chimia.2015.52.

PMID:
28982464
31.

Silver nanoparticle effects on stream periphyton during short-term exposures.

Gil-Allué C, Schirmer K, Tlili A, Gessner MO, Behra R.

Environ Sci Technol. 2015 Jan 20;49(2):1165-72.

PMID:
25513720
32.

Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in fish.

Groh KJ, Carvalho RN, Chipman JK, Denslow ND, Halder M, Murphy CA, Roelofs D, Rolaki A, Schirmer K, Watanabe KH.

Chemosphere. 2015 Feb;120:778-92. doi: 10.1016/j.chemosphere.2014.10.006. Epub 2014 Oct 30. Review.

33.

Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: I. Challenges and research needs in ecotoxicology.

Groh KJ, Carvalho RN, Chipman JK, Denslow ND, Halder M, Murphy CA, Roelofs D, Rolaki A, Schirmer K, Watanabe KH.

Chemosphere. 2015 Feb;120:764-77. doi: 10.1016/j.chemosphere.2014.09.068. Epub 2014 Nov 11. Review.

34.

LC-MS/MS determination of potential endocrine disruptors of cortico signalling in rivers and wastewaters.

Ammann AA, Macikova P, Groh KJ, Schirmer K, Suter MJ.

Anal Bioanal Chem. 2014 Nov;406(29):7653-65. doi: 10.1007/s00216-014-8206-9. Epub 2014 Oct 7. Erratum in: Anal Bioanal Chem. 2016 Jul;408(17):4821-2.

PMID:
25286876
35.

Endocrine disrupting compounds affecting corticosteroid signaling pathways in Czech and Swiss waters: potential impact on fish.

Macikova P, Groh KJ, Ammann AA, Schirmer K, Suter MJ.

Environ Sci Technol. 2014 Nov 4;48(21):12902-11. doi: 10.1021/es502711c. Epub 2014 Oct 16.

PMID:
25269596
36.

Development of mutagenicity during degradation of N-nitrosamines by advanced oxidation processes.

Mestankova H, Schirmer K, Canonica S, von Gunten U.

Water Res. 2014 Dec 1;66:399-410. doi: 10.1016/j.watres.2014.08.012. Epub 2014 Aug 21.

PMID:
25240607
37.

Effect of TiO2 nanoparticles and UV radiation on extracellular enzyme activity of intact heterotrophic biofilms.

Schug H, Isaacson CW, Sigg L, Ammann AA, Schirmer K.

Environ Sci Technol. 2014 Oct 7;48(19):11620-8. doi: 10.1021/es502620e. Epub 2014 Sep 29.

PMID:
25208344
38.

Mixtures of chemical pollutants at European legislation safety concentrations: how safe are they?

Carvalho RN, Arukwe A, Ait-Aissa S, Bado-Nilles A, Balzamo S, Baun A, Belkin S, Blaha L, Brion F, Conti D, Creusot N, Essig Y, Ferrero VE, Flander-Putrle V, Fürhacker M, Grillari-Voglauer R, Hogstrand C, Jonáš A, Kharlyngdoh JB, Loos R, Lundebye AK, Modig C, Olsson PE, Pillai S, Polak N, Potalivo M, Sanchez W, Schifferli A, Schirmer K, Sforzini S, Stürzenbaum SR, Søfteland L, Turk V, Viarengo A, Werner I, Yagur-Kroll S, Zounková R, Lettieri T.

Toxicol Sci. 2014 Sep;141(1):218-33. doi: 10.1093/toxsci/kfu118. Epub 2014 Jun 23.

39.

Effects of clofibric acid alone and in combination with 17β-estradiol on mRNA abundance in primary hepatocytes isolated from rainbow trout.

Sovadinová I, Liedtke A, Schirmer K.

Toxicol In Vitro. 2014 Sep;28(6):1106-16. doi: 10.1016/j.tiv.2014.05.002. Epub 2014 May 28.

PMID:
24880017
40.

Importance of toxicokinetics for interspecies variation in sensitivity to chemicals.

Nyman AM, Schirmer K, Ashauer R.

Environ Sci Technol. 2014 May 20;48(10):5946-54. doi: 10.1021/es5005126. Epub 2014 May 2.

PMID:
24758734
41.

Measured and modeled toxicokinetics in cultured fish cells and application to in vitro-in vivo toxicity extrapolation.

Stadnicka-Michalak J, Tanneberger K, Schirmer K, Ashauer R.

PLoS One. 2014 Mar 19;9(3):e92303. doi: 10.1371/journal.pone.0092303. eCollection 2014.

42.

Critical influence of chloride ions on silver ion-mediated acute toxicity of silver nanoparticles to zebrafish embryos.

Groh KJ, Dalkvist T, Piccapietra F, Behra R, Suter MJ, Schirmer K.

Nanotoxicology. 2015 Feb;9(1):81-91. doi: 10.3109/17435390.2014.893379. Epub 2014 Mar 14.

PMID:
24625062
43.

Toxicity of silver nanoparticles to a fish gill cell line: role of medium composition.

Yue Y, Behra R, Sigg L, Fernández Freire P, Pillai S, Schirmer K.

Nanotoxicology. 2015 Feb;9(1):54-63. doi: 10.3109/17435390.2014.889236. Epub 2014 Mar 12.

PMID:
24621324
44.

Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver.

Pillai S, Behra R, Nestler H, Suter MJ, Sigg L, Schirmer K.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3490-5. doi: 10.1073/pnas.1319388111. Epub 2014 Feb 18.

45.

Systems toxicology approach to understand the kinetics of benzo(a)pyrene uptake, biotransformation, and DNA adduct formation in a liver cell model.

Madureira DJ, Weiss FT, Van Midwoud P, Helbling DE, Sturla SJ, Schirmer K.

Chem Res Toxicol. 2014 Mar 17;27(3):443-53. doi: 10.1021/tx400446q. Epub 2014 Feb 13.

PMID:
24446834
46.

Systems toxicology: from basic research to risk assessment.

Sturla SJ, Boobis AR, FitzGerald RE, Hoeng J, Kavlock RJ, Schirmer K, Whelan M, Wilks MF, Peitsch MC.

Chem Res Toxicol. 2014 Mar 17;27(3):314-29. doi: 10.1021/tx400410s. Epub 2014 Jan 21.

47.

A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment.

Scholz S, Sela E, Blaha L, Braunbeck T, Galay-Burgos M, García-Franco M, Guinea J, Klüver N, Schirmer K, Tanneberger K, Tobor-Kapłon M, Witters H, Belanger S, Benfenati E, Creton S, Cronin MT, Eggen RI, Embry M, Ekman D, Gourmelon A, Halder M, Hardy B, Hartung T, Hubesch B, Jungmann D, Lampi MA, Lee L, Léonard M, Küster E, Lillicrap A, Luckenbach T, Murk AJ, Navas JM, Peijnenburg W, Repetto G, Salinas E, Schüürmann G, Spielmann H, Tollefsen KE, Walter-Rohde S, Whale G, Wheeler JR, Winter MJ.

Regul Toxicol Pharmacol. 2013 Dec;67(3):506-30. doi: 10.1016/j.yrtph.2013.10.003. Epub 2013 Oct 23. Review.

PMID:
24161465
48.

Investigating alternatives to the fish early-life stage test: a strategy for discovering and annotating adverse outcome pathways for early fish development.

Villeneuve D, Volz DC, Embry MR, Ankley GT, Belanger SE, Léonard M, Schirmer K, Tanguay R, Truong L, Wehmas L.

Environ Toxicol Chem. 2014 Jan;33(1):158-69. doi: 10.1002/etc.2403. Epub 2013 Nov 19.

49.

Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos.

Fischer S, Klüver N, Burkhardt-Medicke K, Pietsch M, Schmidt AM, Wellner P, Schirmer K, Luckenbach T.

BMC Biol. 2013 Jun 17;11:69. doi: 10.1186/1741-7007-11-69.

50.

Testing nanomaterial toxicity in unicellular eukaryotic algae and fish cell lines.

Kroll A, Kühnel D, Schirmer K.

Methods Mol Biol. 2013;1028:165-95. doi: 10.1007/978-1-62703-475-3_11.

PMID:
23740120

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