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A single night of sleep loss impairs objective but not subjective working memory performance in a sex-dependent manner.

Rångtell FH, Karamchedu S, Andersson P, Liethof L, Olaya Búcaro M, Lampola L, Schiöth HB, Cedernaes J, Benedict C.

J Sleep Res. 2018 Jan 31. doi: 10.1111/jsr.12651. [Epub ahead of print]


Experimenter gender and replicability in science.

Chapman CD, Benedict C, Schiöth HB.

Sci Adv. 2018 Jan 10;4(1):e1701427. doi: 10.1126/sciadv.1701427. eCollection 2018 Jan. Review.


Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents.

Jokinen J, Boström AE, Dadfar A, Ciuculete DM, Chatzittofis A, Åsberg M, Schiöth HB.

EBioMedicine. 2018 Jan;27:123-133. doi: 10.1016/j.ebiom.2017.12.018. Epub 2017 Dec 18.


Atypical anorexia nervosa is not related to brain structural changes in newly diagnosed adolescent patients.

Olivo G, Solstrand Dahlberg L, Wiemerslage L, Swenne I, Zhukovsky C, Salonen-Ros H, Larsson EM, Gaudio S, Brooks SJ, Schiöth HB.

Int J Eat Disord. 2018 Jan;51(1):39-45. doi: 10.1002/eat.22805. Epub 2017 Dec 7.


Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359.

Crüsemann M, Reher R, Schamari I, Brachmann AO, Ohbayashi T, Kuschak M, Malfacini D, Seidinger A, Pinto-Carbó M, Richarz R, Reuter T, Kehraus S, Hallab A, Attwood M, Schiöth HB, Mergaert P, Kikuchi Y, Schäberle TF, Kostenis E, Wenzel D, Müller CE, Piel J, Carlier A, Eberl L, König GM.

Angew Chem Int Ed Engl. 2018 Jan 15;57(3):836-840. doi: 10.1002/anie.201707996. Epub 2017 Dec 20.


Intranasal insulin in Alzheimer's disease: Food for thought.

Chapman CD, Schiöth HB, Grillo CA, Benedict C.

Neuropharmacology. 2017 Nov 24. pii: S0028-3908(17)30566-X. doi: 10.1016/j.neuropharm.2017.11.037. [Epub ahead of print] Review.


Trends in GPCR drug discovery: new agents, targets and indications.

Hauser AS, Attwood MM, Rask-Andersen M, Schiöth HB, Gloriam DE.

Nat Rev Drug Discov. 2017 Dec;16(12):829-842. doi: 10.1038/nrd.2017.178. Epub 2017 Oct 27. Review.


IL-1β reduces GluA1 phosphorylation and its surface expression during memory reconsolidation and α-melanocyte-stimulating hormone can modulate these effects.

Machado I, Schiöth HB, Lasaga M, Scimonelli T.

Neuropharmacology. 2018 Jan;128:314-323. doi: 10.1016/j.neuropharm.2017.09.041. Epub 2017 Oct 14.


The Role of Working Memory for Cognitive Control in Anorexia Nervosa versus Substance Use Disorder.

Brooks SJ, Funk SG, Young SY, Schiöth HB.

Front Psychol. 2017 Sep 22;8:1651. doi: 10.3389/fpsyg.2017.01651. eCollection 2017. Review.


Response to Leusink et al.

Ciuculete DM, Schiöth HB, Mwinyi J.

Clin Genet. 2017 Nov;92(5):566. doi: 10.1111/cge.13042. No abstract available.


Highly diversified expansions shaped the evolution of membrane bound proteins in metazoans.

Attwood MM, Krishnan A, Almén MS, Schiöth HB.

Sci Rep. 2017 Sep 28;7(1):12387. doi: 10.1038/s41598-017-11543-z.


Resting-state brain connectivity changes in obese women after Roux-en-Y gastric bypass surgery: A longitudinal study.

Olivo G, Zhou W, Sundbom M, Zhukovsky C, Hogenkamp P, Nikontovic L, Stark J, Wiemerslage L, Larsson EM, Benedict C, Schiöth HB.

Sci Rep. 2017 Jul 26;7(1):6616. doi: 10.1038/s41598-017-06663-5.


A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers.

Xu J, Boström AE, Saeed M, Dubey RK, Waeber G, Vollenweider P, Marques-Vidal P, Mwinyi J, Schiöth HB.

Medicine (Baltimore). 2017 Jul;96(30):e7029. doi: 10.1097/MD.0000000000007029.


A genetic risk score is differentially associated with migraine with and without aura.

Pisanu C, Preisig M, Castelao E, Glaus J, Pistis G, Squassina A, Del Zompo M, Merikangas KR, Waeber G, Vollenweider P, Mwinyi J, Schiöth HB.

Hum Genet. 2017 Aug;136(8):999-1008. doi: 10.1007/s00439-017-1816-5. Epub 2017 Jun 27.


A MIR4646 associated methylation locus is hypomethylated in adolescent depression.

Boström AE, Ciuculete DM, Attwood M, Krattinger R, Nikontovic L, Titova OE, Kullak-Ublick GA, Mwinyi J, Schiöth HB.

J Affect Disord. 2017 Oct 1;220:117-128. doi: 10.1016/j.jad.2017.05.017. Epub 2017 May 17.


Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake.

Chicca A, Nicolussi S, Bartholomäus R, Blunder M, Aparisi Rey A, Petrucci V, Reynoso-Moreno IDC, Viveros-Paredes JM, Dalghi Gens M, Lutz B, Schiöth HB, Soeberdt M, Abels C, Charles RP, Altmann KH, Gertsch J.

Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):E5006-E5015. doi: 10.1073/pnas.1704065114. Epub 2017 Jun 5.


Correction: Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus.

Mwinyi J, Boström A, Fehrer I, Othman A, Waeber G, Marti-Soler H, Vollenweider P, Marques-Vidal P, Schiöth HB, von Eckardstein A, Hornemann T.

PLoS One. 2017 Jun 5;12(6):e0179313. doi: 10.1371/journal.pone.0179313. eCollection 2017.


Sex matters: Report experimenter gender.

Chapman CD, Benedict C, Schiöth HB.

Science. 2017 Jun 2;356(6341):916-917. doi: 10.1126/science.aan5448. No abstract available.


Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus.

Mwinyi J, Boström A, Fehrer I, Othman A, Waeber G, Marti-Soler H, Vollenweider P, Marques-Vidal P, Schiöth HB, von Eckardstein A, Hornemann T.

PLoS One. 2017 May 4;12(5):e0175776. doi: 10.1371/journal.pone.0175776. eCollection 2017. Erratum in: PLoS One. 2017 Jun 5;12 (6):e0179313.


Correction: Limbic-thalamo-cortical projections and reward-related circuitry integrity affects eating behavior: A longitudinal DTI study in adolescents with restrictive eating disorders.

Olivo G, Wiemerslage L, Swenne I, Zhukovsky C, Salonen-Ros H, Larsson EM, Gaudio S, Brooks SJ, Schiöth HB.

PLoS One. 2017 Apr 20;12(4):e0176646. doi: 10.1371/journal.pone.0176646. eCollection 2017.


Diffusion tensor imaging and tractography of the white matter in normal aging: The rate-of-change differs between segments within tracts.

Mårtensson J, Lätt J, Åhs F, Fredrikson M, Söderlund H, Schiöth HB, Kok J, Kremer B, van Westen D, Larsson EM, Nilsson M.

Magn Reson Imaging. 2018 Jan;45:113-119. doi: 10.1016/j.mri.2017.03.007. Epub 2017 Mar 27.


The impact of cognitive training in substance use disorder: the effect of working memory training on impulse control in methamphetamine users.

Brooks SJ, Wiemerslage L, Burch KH, Maiorana SA, Cocolas E, Schiöth HB, Kamaloodien K, Stein DJ.

Psychopharmacology (Berl). 2017 Jun;234(12):1911-1921. doi: 10.1007/s00213-017-4597-6. Epub 2017 Mar 21.


Methylation of HPA axis related genes in men with hypersexual disorder.

Jokinen J, Boström AE, Chatzittofis A, Ciuculete DM, Öberg KG, Flanagan JN, Arver S, Schiöth HB.

Psychoneuroendocrinology. 2017 Jun;80:67-73. doi: 10.1016/j.psyneuen.2017.03.007. Epub 2017 Mar 10.


Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction.

Edvinsson Å, Bränn E, Hellgren C, Freyhult E, White R, Kamali-Moghaddam M, Olivier J, Bergquist J, Boström AE, Schiöth HB, Skalkidou A, Cunningham JL, Sundström-Poromaa I.

Psychoneuroendocrinology. 2017 Jun;80:15-25. doi: 10.1016/j.psyneuen.2017.02.027. Epub 2017 Feb 28.


Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study.

Bränn E, Papadopoulos F, Fransson E, White R, Edvinsson Å, Hellgren C, Kamali-Moghaddam M, Boström A, Schiöth HB, Sundström-Poromaa I, Skalkidou A.

Psychoneuroendocrinology. 2017 May;79:146-159. doi: 10.1016/j.psyneuen.2017.02.029. Epub 2017 Feb 28.


Limbic-thalamo-cortical projections and reward-related circuitry integrity affects eating behavior: A longitudinal DTI study in adolescents with restrictive eating disorders.

Olivo G, Wiemerslage L, Swenne I, Zhukowsky C, Salonen-Ros H, Larsson EM, Gaudio S, Brooks SJ, Schiöth HB.

PLoS One. 2017 Mar 1;12(3):e0172129. doi: 10.1371/journal.pone.0172129. eCollection 2017. Erratum in: PLoS One. 2017 Apr 20;12 (4):e0176646.


Anxiety Disorders are Associated with Low Socioeconomic Status in Women but Not in Men.

Mwinyi J, Pisanu C, Castelao E, Stringhini S, Preisig M, Schiöth HB.

Womens Health Issues. 2017 May - Jun;27(3):302-307. doi: 10.1016/j.whi.2017.01.001. Epub 2017 Feb 15.


A DNA methylation site within the KLF13 gene is associated with orexigenic processes based on neural responses and ghrelin levels.

Wiemerslage L, Islam R, van der Kamp C, Cao H, Olivo G, Ence-Eriksson F, Castillo S, Larsen AL, Bandstein M, Dahlberg LS, Perland E, Gustavsson V, Nilsson J, Vogel H, Schürmann A, Larsson EM, Rask-Andersen M, Benedict C, Schiöth HB.

Int J Obes (Lond). 2017 Jun;41(6):990-994. doi: 10.1038/ijo.2017.43. Epub 2017 Feb 14.


A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score.

Ciuculete DM, Boström AE, Voisin S, Philipps H, Titova OE, Bandstein M, Nikontovic L, Williams MJ, Mwinyi J, Schiöth HB.

Transl Psychiatry. 2017 Jan 17;7(1):e1002. doi: 10.1038/tp.2016.275.


Melanocortin 4 receptor constitutive activity inhibits L-type voltage-gated calcium channels in neurons.

Agosti F, Cordisco Gonzalez S, Martinez Damonte V, Tolosa MJ, Di Siervi N, Schioth HB, Davio C, Perello M, Raingo J.

Neuroscience. 2017 Mar 27;346:102-112. doi: 10.1016/j.neuroscience.2017.01.007. Epub 2017 Jan 16.


NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition.

Mwinyi J, Boström AE, Pisanu C, Murphy SK, Erhart W, Schafmayer C, Hampe J, Moylan C, Schiöth HB.

Biochim Biophys Acta. 2017 Mar;1862(3):314-323. doi: 10.1016/j.bbalip.2016.12.005. Epub 2016 Dec 18.


A genetic risk score is significantly associated with statin therapy response in the elderly population.

Ciuculete DM, Bandstein M, Benedict C, Waeber G, Vollenweider P, Lind L, Schiöth HB, Mwinyi J.

Clin Genet. 2017 Mar;91(3):379-385. doi: 10.1111/cge.12890. Epub 2016 Dec 12.


Adolescents newly diagnosed with eating disorders have structural differences in brain regions linked with eating disorder symptoms.

Solstrand Dahlberg L, Wiemerslage L, Swenne I, Larsen A, Stark J, Rask-Andersen M, Salonen-Ros H, Larsson EM, Schiöth HB, Brooks SJ.

Nord J Psychiatry. 2017 Apr;71(3):188-196. doi: 10.1080/08039488.2016.1250948. Epub 2016 Nov 15.


Classification, Nomenclature, and Structural Aspects of Adhesion GPCRs.

Krishnan A, Nijmeijer S, de Graaf C, Schiöth HB.

Handb Exp Pharmacol. 2016;234:15-41. Review.


A resting-state fMRI study of obese females between pre- and postprandial states before and after bariatric surgery.

Wiemerslage L, Zhou W, Olivo G, Stark J, Hogenkamp PS, Larsson EM, Sundbom M, Schiöth HB.

Eur J Neurosci. 2017 Feb;45(3):333-341. doi: 10.1111/ejn.13428. Epub 2016 Nov 1.


A systematic review of resting-state functional-MRI studies in anorexia nervosa: Evidence for functional connectivity impairment in cognitive control and visuospatial and body-signal integration.

Gaudio S, Wiemerslage L, Brooks SJ, Schiöth HB.

Neurosci Biobehav Rev. 2016 Dec;71:578-589. doi: 10.1016/j.neubiorev.2016.09.032. Epub 2016 Oct 8. Review.


Sleep restriction alters plasma endocannabinoids concentrations before but not after exercise in humans.

Cedernaes J, Fanelli F, Fazzini A, Pagotto U, Broman JE, Vogel H, Dickson SL, Schiöth HB, Benedict C.

Psychoneuroendocrinology. 2016 Dec;74:258-268. doi: 10.1016/j.psyneuen.2016.09.014. Epub 2016 Sep 22.


Psychological intervention with working memory training increases basal ganglia volume: A VBM study of inpatient treatment for methamphetamine use.

Brooks SJ, Burch KH, Maiorana SA, Cocolas E, Schioth HB, Nilsson EK, Kamaloodien K, Stein DJ.

Neuroimage Clin. 2016 Aug 24;12:478-91. doi: 10.1016/j.nicl.2016.08.019. eCollection 2016.


One-night sleep deprivation induces changes in the DNA methylation and serum activity indices of stearoyl-CoA desaturase in young healthy men.

Skuladottir GV, Nilsson EK, Mwinyi J, Schiöth HB.

Lipids Health Dis. 2016 Aug 26;15(1):137. doi: 10.1186/s12944-016-0309-1.


Two hours of evening reading on a self-luminous tablet vs. reading a physical book does not alter sleep after daytime bright light exposure.

Rångtell FH, Ekstrand E, Rapp L, Lagermalm A, Liethof L, Búcaro MO, Lingfors D, Broman JE, Schiöth HB, Benedict C.

Sleep Med. 2016 Jul;23:111-118. doi: 10.1016/j.sleep.2016.06.016. Epub 2016 Jul 25.


Recurrent Sleep Fragmentation Induces Insulin and Neuroprotective Mechanisms in Middle-Aged Flies.

Williams MJ, Perland E, Eriksson MM, Carlsson J, Erlandsson D, Laan L, Mahebali T, Potter E, Frediksson R, Benedict C, Schiöth HB.

Front Aging Neurosci. 2016 Aug 2;8:180. doi: 10.3389/fnagi.2016.00180. eCollection 2016.


Association between shift work history and performance on the trail making test in middle-aged and elderly humans: the EpiHealth study.

Titova OE, Lindberg E, Elmståhl S, Lind L, Schiöth HB, Benedict C.

Neurobiol Aging. 2016 Sep;45:23-29. doi: 10.1016/j.neurobiolaging.2016.05.007. Epub 2016 May 14.


Postprandial alterations in whole-blood DNA methylation are mediated by changes in white blood cell composition.

Rask-Andersen M, Bringeland N, Nilsson EK, Bandstein M, Olaya Búcaro M, Vogel H, Schürmann A, Hogenkamp PS, Benedict C, Schiöth HB.

Am J Clin Nutr. 2016 Aug;104(2):518-25. doi: 10.3945/ajcn.115.122366. Epub 2016 Jul 6.


Higher resting-state activity in reward-related brain circuits in obese versus normal-weight females independent of food intake.

Hogenkamp PS, Zhou W, Dahlberg LS, Stark J, Larsen AL, Olivo G, Wiemerslage L, Larsson EM, Sundbom M, Benedict C, Schiöth HB.

Int J Obes (Lond). 2016 Nov;40(11):1687-1692. doi: 10.1038/ijo.2016.105. Epub 2016 Jun 7.


A new, simple and robust radioligand binding method used to determine kinetic off-rate constants for unlabeled ligands. Application at α2A- and α2C-adrenoceptors.

Uhlén S, Schiöth HB, Jahnsen JA.

Eur J Pharmacol. 2016 Oct 5;788:113-121. doi: 10.1016/j.ejphar.2016.06.021. Epub 2016 Jun 16.


Epigenomics of Total Acute Sleep Deprivation in Relation to Genome-Wide DNA Methylation Profiles and RNA Expression.

Nilsson EK, Boström AE, Mwinyi J, Schiöth HB.

OMICS. 2016 Jun;20(6):334-42. doi: 10.1089/omi.2016.0041.


A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease.

Schiöth HB, Boström A, Murphy SK, Erhart W, Hampe J, Moylan C, Mwinyi J.

BMC Genomics. 2016 Jun 14;17:462. doi: 10.1186/s12864-016-2814-z.


The Drosophila ETV5 Homologue Ets96B: Molecular Link between Obesity and Bipolar Disorder.

Williams MJ, Klockars A, Eriksson A, Voisin S, Dnyansagar R, Wiemerslage L, Kasagiannis A, Akram M, Kheder S, Ambrosi V, Hallqvist E, Fredriksson R, Schiöth HB.

PLoS Genet. 2016 Jun 9;12(6):e1006104. doi: 10.1371/journal.pgen.1006104. eCollection 2016 Jun.


BDNF DNA methylation changes as a biomarker of psychiatric disorders: literature review and open access database analysis.

Zheleznyakova GY, Cao H, Schiöth HB.

Behav Brain Funct. 2016 Jun 6;12(1):17. doi: 10.1186/s12993-016-0101-4. Review.


A genetic variant in proximity to the gene LYPLAL1 is associated with lower hunger feelings and increased weight loss following Roux-en-Y gastric bypass surgery.

Bandstein M, Mwinyi J, Ernst B, Thurnheer M, Schultes B, Schiöth HB.

Scand J Gastroenterol. 2016 Sep;51(9):1050-5. doi: 10.3109/00365521.2016.1166519. Epub 2016 May 16.

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