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Items: 14


CDK4/6 inhibition triggers anti-tumour immunity.

Goel S, DeCristo MJ, Watt AC, BrinJones H, Sceneay J, Li BB, Khan N, Ubellacker JM, Xie S, Metzger-Filho O, Hoog J, Ellis MJ, Ma CX, Ramm S, Krop IE, Winer EP, Roberts TM, Kim HJ, McAllister SS, Zhao JJ.

Nature. 2017 Aug 24;548(7668):471-475. doi: 10.1038/nature23465. Epub 2017 Aug 16.


The skinny on obesity and cancer.

Sceneay J, McAllister SS.

Nat Cell Biol. 2017 Jul 28;19(8):887-888. doi: 10.1038/ncb3583.


The Biodistribution and Immune Suppressive Effects of Breast Cancer-Derived Exosomes.

Wen SW, Sceneay J, Lima LG, Wong CS, Becker M, Krumeich S, Lobb RJ, Castillo V, Wong KN, Ellis S, Parker BS, Möller A.

Cancer Res. 2016 Dec 1;76(23):6816-6827. Epub 2016 Oct 19.


Hematopoietic Age at Onset of Triple-Negative Breast Cancer Dictates Disease Aggressiveness and Progression.

Marsh T, Wong I, Sceneay J, Barakat A, Qin Y, Sjödin A, Alspach E, Nilsson B, Stewart SA, McAllister SS.

Cancer Res. 2016 May 15;76(10):2932-43. doi: 10.1158/0008-5472.CAN-15-3332. Epub 2016 Apr 7.


Toll-like receptor 3 regulates NK cell responses to cytokines and controls experimental metastasis.

Guillerey C, Chow MT, Miles K, Olver S, Sceneay J, Takeda K, Möller A, Smyth MJ.

Oncoimmunology. 2015 Apr 2;4(9):e1027468. eCollection 2015 Sep.


Carbonic anhydrase IX promotes myeloid-derived suppressor cell mobilization and establishment of a metastatic niche by stimulating G-CSF production.

Chafe SC, Lou Y, Sceneay J, Vallejo M, Hamilton MJ, McDonald PC, Bennewith KL, Möller A, Dedhar S.

Cancer Res. 2015 Mar 15;75(6):996-1008. doi: 10.1158/0008-5472.CAN-14-3000. Epub 2015 Jan 26.


The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer.

Chen A, Wong CS, Liu MC, House CM, Sceneay J, Bowtell DD, Thompson EW, Möller A.

Oncotarget. 2015 Jan 20;6(2):862-73.


The antioxidant N-acetylcysteine prevents HIF-1 stabilization under hypoxia in vitro but does not affect tumorigenesis in multiple breast cancer models in vivo.

Sceneay J, Liu MC, Chen A, Wong CS, Bowtell DD, Möller A.

PLoS One. 2013 Jun 20;8(6):e66388. doi: 10.1371/journal.pone.0066388. Print 2013.


The pre-metastatic niche: finding common ground.

Sceneay J, Smyth MJ, Möller A.

Cancer Metastasis Rev. 2013 Dec;32(3-4):449-64. doi: 10.1007/s10555-013-9420-1. Review.


Hypoxia-driven immunosuppression contributes to the pre-metastatic niche.

Sceneay J, Parker BS, Smyth MJ, Möller A.

Oncoimmunology. 2013 Jan 1;2(1):e22355.


NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases.

Chow MT, Sceneay J, Paget C, Wong CS, Duret H, Tschopp J, Möller A, Smyth MJ.

Cancer Res. 2012 Nov 15;72(22):5721-32. doi: 10.1158/0008-5472.CAN-12-0509. Epub 2012 Sep 17.


Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche.

Sceneay J, Chow MT, Chen A, Halse HM, Wong CS, Andrews DM, Sloan EK, Parker BS, Bowtell DD, Smyth MJ, Möller A.

Cancer Res. 2012 Aug 15;72(16):3906-11. doi: 10.1158/0008-5472.CAN-11-3873. Epub 2012 Jul 2.


Vascular normalization by loss of Siah2 results in increased chemotherapeutic efficacy.

Wong CS, Sceneay J, House CM, Halse HM, Liu MC, George J, Hunnam TC, Parker BS, Haviv I, Ronai Z, Cullinane C, Bowtell DD, Möller A.

Cancer Res. 2012 Apr 1;72(7):1694-704. doi: 10.1158/0008-5472.CAN-11-3310. Epub 2012 Feb 21.


The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression.

Chan P, Möller A, Liu MC, Sceneay JE, Wong CS, Waddell N, Huang KT, Dobrovic A, Millar EK, O'Toole SA, McNeil CM, Sutherland RL, Bowtell DD, Fox SB.

Breast Cancer Res. 2011 Feb 9;13(1):R19. doi: 10.1186/bcr2828.

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