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Items: 1 to 50 of 437

1.

NVP-BHG712: Effects of regioisomers on the affinity and selectivity towards the EPHrin family.

Schwalbe H, Tröster A, Heinzlmeir S, Berger BT, Gande SL, Saxena K, Sreeramulu S, Linhard V, Nasiri AH, Bolte M, Müller S, Kuster B, Médard G, Kudlinzki D.

ChemMedChem. 2018 Jun 21. doi: 10.1002/cmdc.201800398. [Epub ahead of print]

PMID:
29928781
2.

Modulation of the Allosteric Communication between the Polo-Box Domain and the Catalytic Domain in Plk1 by Small Compounds.

Raab M, Sanhaji M, Pietsch L, Béquignon I, Herbrand AK, Süß E, Gande SL, Caspar B, Kudlinzki D, Saxena K, Sreeramulu S, Schwalbe H, Strebhardt K, Biondi RM.

ACS Chem Biol. 2018 Jun 28. doi: 10.1021/acschembio.7b01078. [Epub ahead of print]

PMID:
29927572
3.

Paradoxically, Most Flexible Ligand Binds Most Entropy-Favored: Intriguing Impact of Ligand Flexibility and Solvation on Drug-Kinase Binding.

Wienen-Schmidt B, Jonker HRA, Wulsdorf T, Gerber HD, Saxena K, Kudlinzki D, Sreeramulu S, Parigi G, Luchinat C, Heine A, Schwalbe H, Klebe G.

J Med Chem. 2018 Jul 3. doi: 10.1021/acs.jmedchem.8b00105. [Epub ahead of print]

PMID:
29909615
4.

Experiential contributions to social dominance in a rat model of fragile-X syndrome.

Saxena K, Webster J, Hallas-Potts A, Mackenzie R, Spooner PA, Thomson D, Kind P, Chatterji S, Morris RGM.

Proc Biol Sci. 2018 Jun 13;285(1880). pii: 20180294. doi: 10.1098/rspb.2018.0294.

PMID:
29899064
5.

Provider Adoption of Speech Recognition and its Impact on Satisfaction, Documentation Quality, Efficiency, and Cost in an Inpatient EHR.

Saxena K, Diamond R, Conant RF, Mitchell TH, Gallopyn IG, Yakimow KE.

AMIA Jt Summits Transl Sci Proc. 2018 May 18;2017:186-195. eCollection 2018.

6.

Breeding pigeonpea cultivars for intercropping: synthesis and strategies.

Saxena KB, Choudhary AK, Saxena RK, Varshney RK.

Breed Sci. 2018 Mar;68(2):159-167. doi: 10.1270/jsbbs.17105. Epub 2018 Apr 12. Review.

7.

Pallister-Killian syndrome: Review of fetal phenotype.

Thakur S, Gupta R, Tiwari B, Singh N, Saxena KK.

Clin Genet. 2018 May 22. doi: 10.1111/cge.13381. [Epub ahead of print]

PMID:
29790157
8.

Role of magnetic resonance imaging in breast cancer management.

Radhakrishna S, Agarwal S, Parikh PM, Kaur K, Panwar S, Sharma S, Dey A, Saxena KK, Chandra M, Sud S.

South Asian J Cancer. 2018 Apr-Jun;7(2):69-71. doi: 10.4103/sajc.sajc_104_18.

9.

Molecular mapping and inheritance of restoration of fertility (Rf) in A4 hybrid system in pigeonpea (Cajanus cajan (L.) Millsp.).

Saxena RK, Patel K, Sameer Kumar CV, Tyagi K, Saxena KB, Varshney RK.

Theor Appl Genet. 2018 Aug;131(8):1605-1614. doi: 10.1007/s00122-018-3101-y. Epub 2018 Apr 28.

PMID:
29705915
10.

Structural Characterization of the Interaction of the Fibroblast Growth Factor Receptor with a Small Molecule Allosteric Inhibitor.

Kappert F, Sreeramulu S, Jonker HRA, Richter C, Rogov VV, Proschak E, Hargittay B, Saxena K, Schwalbe H.

Chemistry. 2018 Jun 4;24(31):7861-7865. doi: 10.1002/chem.201801770. Epub 2018 May 3.

PMID:
29656465
11.

Role of Brain Biomarker in Predicting Clinical Outcome in Hypertensive Cerebrovascular Ischemic Stroke.

Bharosay A, Bharosay VV, Saxena K, Varma M.

Indian J Clin Biochem. 2018 Apr;33(2):178-183. doi: 10.1007/s12291-017-0664-3. Epub 2017 May 20.

PMID:
29651208
12.

Patient with Persistent Low Oxygen Saturation for Emergency Cesarean Section.

Panwar S, Saxena KN, Gaba P.

Anesth Essays Res. 2017 Jul-Sep;11(3):778-780. doi: 10.4103/0259-1162.194348.

13.

Photobiomodulation with 670 nm light ameliorates Müller cell-mediated activation of microglia and macrophages in retinal degeneration.

Lu YZ, Natoli R, Madigan M, Fernando N, Saxena K, Aggio-Bruce R, Jiao H, Provis J, Valter K.

Exp Eye Res. 2017 Dec;165:78-89. doi: 10.1016/j.exer.2017.09.002. Epub 2017 Sep 6.

PMID:
28888911
14.

Occurrence of Kounis syndrome under anesthesia.

Kerai S, Sehrawat L, Saxena KN, Taneja B.

J Anaesthesiol Clin Pharmacol. 2017 Apr-Jun;33(2):276-277. doi: 10.4103/0970-9185.209737. No abstract available.

15.

Body to Scalp: Evolving Trends in Body Hair Transplantation.

Saxena K, Savant SS.

Indian Dermatol Online J. 2017 May-Jun;8(3):167-175. doi: 10.4103/idoj.IDOJ_283_16. Review.

16.

Chemoproteomics-Aided Medicinal Chemistry for the Discovery of EPHA2 Inhibitors.

Heinzlmeir S, Lohse J, Treiber T, Kudlinzki D, Linhard V, Gande SL, Sreeramulu S, Saxena K, Liu X, Wilhelm M, Schwalbe H, Kuster B, Médard G.

ChemMedChem. 2017 Jun 21;12(12):999-1011. doi: 10.1002/cmdc.201700217. Epub 2017 Jun 12.

PMID:
28544567
17.

Characterization and mapping of Dt1 locus which co-segregates with CcTFL1 for growth habit in pigeonpea.

Saxena RK, Obala J, Sinjushin A, Kumar CVS, Saxena KB, Varshney RK.

Theor Appl Genet. 2017 Sep;130(9):1773-1784. doi: 10.1007/s00122-017-2924-2. Epub 2017 May 24.

18.

Quadratus lumborum block for post-caesarean analgesia.

Kerai S, Saxena KN.

Indian J Anaesth. 2017 Apr;61(4):364. doi: 10.4103/ija.IJA_220_17. No abstract available.

19.

Construction of genotyping-by-sequencing based high-density genetic maps and QTL mapping for fusarium wilt resistance in pigeonpea.

Saxena RK, Singh VK, Kale SM, Tathineni R, Parupalli S, Kumar V, Garg V, Das RR, Sharma M, Yamini KN, Muniswamy S, Ghanta A, Rathore A, Kumar CVS, Saxena KB, Kishor PBK, Varshney RK.

Sci Rep. 2017 May 15;7(1):1911. doi: 10.1038/s41598-017-01537-2.

20.

Genotyping-by-sequencing of three mapping populations for identification of candidate genomic regions for resistance to sterility mosaic disease in pigeonpea.

Saxena RK, Kale SM, Kumar V, Parupali S, Joshi S, Singh V, Garg V, Das RR, Sharma M, Yamini KN, Ghanta A, Rathore A, Sameerkumar CV, Saxena KB, Varshney RK.

Sci Rep. 2017 May 12;7(1):1813. doi: 10.1038/s41598-017-01535-4.

21.

Erratum to: Antifilarial activity of diterpenoids from Taxodium distichum.

Kushwaha V, Saxena K, Verma R, Verma SK, Katoch D, Kumar N, Lal B, Murthy PK, Singh B.

Parasit Vectors. 2017 Apr 26;10(1):208. doi: 10.1186/s13071-017-2119-3. No abstract available.

22.

Post-caesarean analgesia: What is new?

Kerai S, Saxena KN, Taneja B.

Indian J Anaesth. 2017 Mar;61(3):200-214. doi: 10.4103/ija.IJA_313_16. Review.

23.

Human Intestinal Enteroids: New Models to Study Gastrointestinal Virus Infections.

Zou WY, Blutt SE, Crawford SE, Ettayebi K, Zeng XL, Saxena K, Ramani S, Karandikar UC, Zachos NC, Estes MK.

Methods Mol Biol. 2017 Mar 31. doi: 10.1007/7651_2017_1. [Epub ahead of print]

PMID:
28361480
24.

Vitamin D status in patients with cirrhosis of the liver and their relatives-A case control study from North India.

Kumar R, Kumar P, Saxena KN, Mishra M, Mishra VK, Kumari A, Dwivedi M, Misra SP.

Indian J Gastroenterol. 2017 Jan;36(1):50-55. doi: 10.1007/s12664-017-0727-7. Epub 2017 Feb 8.

PMID:
28176238
25.

The Haemophilia Joint Visualizer: development of a personalized, interactive, web-based tool to help improve adherence to prophylaxis.

Takedani H, Solimeno L, Saxena K, Kalweit L, Mathew P.

Haemophilia. 2017 Mar;23(2):e155-e158. doi: 10.1111/hae.13164. Epub 2017 Jan 22. No abstract available.

PMID:
28111841
26.

A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection.

Saxena K, Simon LM, Zeng XL, Blutt SE, Crawford SE, Sastri NP, Karandikar UC, Ajami NJ, Zachos NC, Kovbasnjuk O, Donowitz M, Conner ME, Shaw CA, Estes MK.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E570-E579. doi: 10.1073/pnas.1615422114. Epub 2017 Jan 9.

27.
28.

Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs.

Heinzlmeir S, Kudlinzki D, Sreeramulu S, Klaeger S, Gande SL, Linhard V, Wilhelm M, Qiao H, Helm D, Ruprecht B, Saxena K, Médard G, Schwalbe H, Kuster B.

ACS Chem Biol. 2016 Dec 16;11(12):3400-3411. Epub 2016 Nov 7.

PMID:
27768280
29.

Social memory goes viral.

Saxena K, Morris RG.

Science. 2016 Sep 30;353(6307):1496-1497. No abstract available.

PMID:
27708089
30.

Expression and Purification of EPHA2 Tyrosine Kinase Domain for Crystallographic and NMR Studies.

Gande SL, Saxena K, Sreeramulu S, Linhard V, Kudlinzki D, Heinzlmeir S, Reichert AJ, Skerra A, Kuster B, Schwalbe H.

Chembiochem. 2016 Dec 2;17(23):2257-2263. doi: 10.1002/cbic.201600483. Epub 2016 Nov 9.

PMID:
27685543
31.

Cost-benefit of appointment-based medication synchronization in community pharmacies.

Patterson JA, Holdford DA, Saxena K.

Am J Manag Care. 2016 Sep;22(9):587-93.

32.

Inverted mask ventilation in a postrhinoplasty patient: Our experience.

Abrar SS, Taneja B, Saxena KN, Varughese SA.

J Anaesthesiol Clin Pharmacol. 2016 Jul-Sep;32(3):412-4. doi: 10.4103/0970-9185.188826. No abstract available.

33.

Molecular Mechanism of SSR128129E, an Extracellularly Acting, Small-Molecule, Allosteric Inhibitor of FGF Receptor Signaling.

Herbert C, Schieborr U, Saxena K, Juraszek J, De Smet F, Alcouffe C, Bianciotto M, Saladino G, Sibrac D, Kudlinzki D, Sreeramulu S, Brown A, Rigon P, Herault JP, Lassalle G, Blundell TL, Rousseau F, Gils A, Schymkowitz J, Tompa P, Herbert JM, Carmeliet P, Gervasio FL, Schwalbe H, Bono F.

Cancer Cell. 2016 Jul 11;30(1):176-178. doi: 10.1016/j.ccell.2016.06.015. Epub 2016 Jul 11. No abstract available.

34.

Efficacy and safety of BAY 81-8973, a full-length recombinant factor VIII: results from the LEOPOLD I trial.

Saxena K, Lalezari S, Oldenburg J, Tseneklidou-Stoeter D, Beckmann H, Yoon M, Maas Enriquez M.

Haemophilia. 2016 Sep;22(5):706-12. doi: 10.1111/hae.12952. Epub 2016 Jun 24.

PMID:
27339736
35.
36.

Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling.

Pawar A, Meier JA, Dasgupta A, Diwanji N, Deshpande N, Saxena K, Buwa N, Inchanalkar S, Schwartz MA, Balasubramanian N.

Cell Signal. 2016 Sep;28(9):1225-36. doi: 10.1016/j.cellsig.2016.05.023. Epub 2016 Jun 4.

37.

Antifilarial activity of diterpenoids from Taxodium distichum.

Kushwaha V, Saxena K, Verma R, Verma SK, Katoch D, Kumar N, Lal B, Murthy PK, Singh B.

Parasit Vectors. 2016 May 31;9(1):312. doi: 10.1186/s13071-016-1592-4. Erratum in: Parasit Vectors. 2017 Apr 26;10 (1):208.

38.

The Role of Pyruvate in Protecting 661W Photoreceptor-Like Cells Against Light-Induced Cell Death.

Natoli R, Rutar M, Lu YZ, Chu-Tan JA, Chen Y, Saxena K, Madigan M, Valter K, Provis JM.

Curr Eye Res. 2016 Nov;41(11):1473-1481. Epub 2016 May 23.

PMID:
27217092
39.

Adenoid basal cell carcinoma: a rare facet of basal cell carcinoma.

Saxena K, Manohar V, Bhakhar V, Bahl S.

BMJ Case Rep. 2016 Apr 19;2016:10.1136/bcr-2015-214166. doi: 10.1136/bcr-2015-214166.

40.

Successful Hair Transplant Outcome in Cicatricial Lichen Planus of the Scalp by Combining Scalp and Beard Hair Along With Platelet Rich Plasma.

Saxena K, Saxena DK, Savant SS.

J Cutan Aesthet Surg. 2016 Jan-Mar;9(1):51-5. doi: 10.4103/0974-2077.178562. No abstract available.

41.

Fiber optic intubation of a neonate with Syngnathia under local anesthesia and sedation.

Saxena KN, Goel V, Taneja B, Gaba P.

J Anaesthesiol Clin Pharmacol. 2016 Jan-Mar;32(1):128-30. doi: 10.4103/0970-9185.175729. No abstract available.

42.

Anesthesia for noncardiac intervention in a patient with total anomalous systemic venous return.

Kerai S, Saxena KN, Sehrawat L, Taneja B.

Paediatr Anaesth. 2016 Mar;26(3):324-5. doi: 10.1111/pan.12804. No abstract available.

PMID:
26814041
43.

Genomics for greater efficiency in pigeonpea hybrid breeding.

Saxena RK, Saxena KB, Pazhamala LT, Patel K, Parupalli S, Sameerkumar CV, Varshney RK.

Front Plant Sci. 2015 Oct 1;6:793. doi: 10.3389/fpls.2015.00793. eCollection 2015. Review.

44.

Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology.

Saxena K, Blutt SE, Ettayebi K, Zeng XL, Broughman JR, Crawford SE, Karandikar UC, Sastri NP, Conner ME, Opekun AR, Graham DY, Qureshi W, Sherman V, Foulke-Abel J, In J, Kovbasnjuk O, Zachos NC, Donowitz M, Estes MK.

J Virol. 2015 Oct 7;90(1):43-56. doi: 10.1128/JVI.01930-15. Print 2016 Jan 1.

45.

Influence of Arrestin on the Photodecay of Bovine Rhodopsin.

Chatterjee D, Eckert CE, Slavov C, Saxena K, Fürtig B, Sanders CR, Gurevich VV, Wachtveitl J, Schwalbe H.

Angew Chem Int Ed Engl. 2015 Nov 9;54(46):13555-60. doi: 10.1002/anie.201505798. Epub 2015 Sep 18.

46.

Optimized Plk1 PBD Inhibitors Based on Poloxin Induce Mitotic Arrest and Apoptosis in Tumor Cells.

Scharow A, Raab M, Saxena K, Sreeramulu S, Kudlinzki D, Gande S, Dötsch C, Kurunci-Csacsko E, Klaeger S, Kuster B, Schwalbe H, Strebhardt K, Berg T.

ACS Chem Biol. 2015 Nov 20;10(11):2570-9. doi: 10.1021/acschembio.5b00565. Epub 2015 Aug 27.

PMID:
26279064
47.

High-resolution crystal structure of cAMP-dependent protein kinase from Cricetulus griseus.

Kudlinzki D, Linhard VL, Saxena K, Sreeramulu S, Gande S, Schieborr U, Dreyer M, Schwalbe H.

Acta Crystallogr F Struct Biol Commun. 2015 Aug;71(Pt 8):1088-93. doi: 10.1107/S2053230X1501242X. Epub 2015 Jul 29.

48.

Impact of Appointment-Based Medication Synchronization on Existing Users of Chronic Medications.

Holdford D, Saxena K.

J Manag Care Spec Pharm. 2015 Aug;21(8):662-9.

49.

Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases.

Farmer LJ, Ledeboer MW, Hoock T, Arnost MJ, Bethiel RS, Bennani YL, Black JJ, Brummel CL, Chakilam A, Dorsch WA, Fan B, Cochran JE, Halas S, Harrington EM, Hogan JK, Howe D, Huang H, Jacobs DH, Laitinen LM, Liao S, Mahajan S, Marone V, Martinez-Botella G, McCarthy P, Messersmith D, Namchuk M, Oh L, Penney MS, Pierce AC, Raybuck SA, Rugg A, Salituro FG, Saxena K, Shannon D, Shlyakter D, Swenson L, Tian SK, Town C, Wang J, Wang T, Wannamaker MW, Winquist RJ, Zuccola HJ.

J Med Chem. 2015 Sep 24;58(18):7195-216. doi: 10.1021/acs.jmedchem.5b00301. Epub 2015 Sep 10.

PMID:
26230873
50.

Enlightening the photoactive site of channelrhodopsin-2 by DNP-enhanced solid-state NMR spectroscopy.

Becker-Baldus J, Bamann C, Saxena K, Gustmann H, Brown LJ, Brown RC, Reiter C, Bamberg E, Wachtveitl J, Schwalbe H, Glaubitz C.

Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9896-901. doi: 10.1073/pnas.1507713112. Epub 2015 Jul 27.

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