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Items: 1 to 50 of 359

1.

Nivolumab for Relapsed/Refractory Classic Hodgkin Lymphoma After Failure of Autologous Hematopoietic Cell Transplantation: Extended Follow-Up of the Multicohort Single-Arm Phase II CheckMate 205 Trial.

Armand P, Engert A, Younes A, Fanale M, Santoro A, Zinzani PL, Timmerman JM, Collins GP, Ramchandren R, Cohen JB, De Boer JP, Kuruvilla J, Savage KJ, Trneny M, Shipp MA, Kato K, Sumbul A, Farsaci B, Ansell SM.

J Clin Oncol. 2018 Mar 27:JCO2017760793. doi: 10.1200/JCO.2017.76.0793. [Epub ahead of print]

PMID:
29584546
2.

Community health workers improve disease control and medication adherence among patients with diabetes and/or hypertension in Chiapas, Mexico: an observational stepped-wedge study.

Newman PM, Franke MF, Arrieta J, Carrasco H, Elliott P, Flores H, Friedman A, Graham S, Martinez L, Palazuelos L, Savage K, Tymeson H, Palazuelos D.

BMJ Glob Health. 2018 Feb 15;3(1):e000566. doi: 10.1136/bmjgh-2017-000566. eCollection 2018.

3.

Protein kinase C zeta suppresses low- or high-grade colorectal cancer (CRC) phenotypes by interphase centrosome anchoring.

Deevi RK, Javadi A, McClements J, Vohhodina J, Savage K, Loughrey MB, Evergren E, Campbell FC.

J Pathol. 2018 Apr;244(4):445-459. doi: 10.1002/path.5035. Epub 2018 Mar 9.

4.

Treatment strategies, outcomes and prognostic factors in 291 patients with secondary CNS involvement by diffuse large B-cell lymphoma.

El-Galaly TC, Cheah CY, Bendtsen MD, Nowakowski GS, Kansara R, Savage KJ, Connors JM, Sehn LH, Goldschmidt N, Shaulov A, Farooq U, Link BK, Ferreri AJM, Calimeri T, Cecchetti C, Dann EJ, Thompson CA, Inbar T, Maurer MJ, Gade IL, Juul MB, Hansen JW, Holmberg S, Larsen TS, Cordua S, Mikhaeel NG, Hutchings M, Seymour JF, Clausen MR, Smith D, Opat S, Gilbertson M, Thanarajasingam G, Villa D.

Eur J Cancer. 2018 Apr;93:57-68. doi: 10.1016/j.ejca.2018.01.073. Epub 2018 Feb 21.

PMID:
29477102
5.

Somatic IL4R Mutations in Primary Mediastinal Large B-cell lymphoma lead to constitutive JAK-STAT signaling activation.

Viganò E, Gunawardana J, Mottok A, Van Tol T, Mak K, Chan FC, Chong L, Chavez E, Woolcock B, Takata K, Twa D, Shulha HP, Telenius A, Kutovaya O, Hung SS, Healy S, Ben-Neriah S, Leroy K, Gaulard P, Diepstra A, Kridel R, Savage KJ, Rimsza L, Gascoyne R, Steidl C.

Blood. 2018 Feb 21. pii: blood-2017-09-808907. doi: 10.1182/blood-2017-09-808907. [Epub ahead of print]

PMID:
29467182
6.

Major Histocompatibility Complex Class II and Programmed Death Ligand 1 Expression Predict Outcome After Programmed Death 1 Blockade in Classic Hodgkin Lymphoma.

Roemer MGM, Redd RA, Cader FZ, Pak CJ, Abdelrahman S, Ouyang J, Sasse S, Younes A, Fanale M, Santoro A, Zinzani PL, Timmerman J, Collins GP, Ramchandren R, Cohen JB, De Boer JP, Kuruvilla J, Savage KJ, Trneny M, Ansell S, Kato K, Farsaci B, Sumbul A, Armand P, Neuberg DS, Pinkus GS, Ligon AH, Rodig SJ, Shipp MA.

J Clin Oncol. 2018 Apr 1;36(10):942-950. doi: 10.1200/JCO.2017.77.3994. Epub 2018 Feb 2.

PMID:
29394125
7.

The pathobiology of primary testicular diffuse large B-cell lymphoma: Implications for novel therapies.

Twa DDW, Mottok A, Savage KJ, Steidl C.

Blood Rev. 2017 Dec 20. pii: S0268-960X(17)30068-1. doi: 10.1016/j.blre.2017.12.001. [Epub ahead of print] Review.

PMID:
29289361
8.

Brentuximab vedotin plus bendamustine in relapsed or refractory Hodgkin's lymphoma: an international, multicentre, single-arm, phase 1-2 trial.

O'Connor OA, Lue JK, Sawas A, Amengual JE, Deng C, Kalac M, Falchi L, Marchi E, Turenne I, Lichtenstein R, Rojas C, Francescone M, Schwartz L, Cheng B, Savage KJ, Villa D, Crump M, Prica A, Kukreti V, Cremers S, Connors JM, Kuruvilla J.

Lancet Oncol. 2018 Feb;19(2):257-266. doi: 10.1016/S1470-2045(17)30912-9. Epub 2017 Dec 21. Erratum in: Lancet Oncol. 2018 Mar;19(3):e137.

PMID:
29276022
9.

Increased Academic Productivity of Orthopaedic Surgery Residents Following 2011 Duty Hour Reform.

Johnson JP, Savage K, Gil JA, Eberson CP, Mulcahey MK.

J Surg Educ. 2017 Dec 19. pii: S1931-7204(16)30371-3. doi: 10.1016/j.jsurg.2017.12.001. [Epub ahead of print]

PMID:
29273338
10.

Brentuximab Vedotin with Chemotherapy for Stage III or IV Hodgkin's Lymphoma.

Connors JM, Jurczak W, Straus DJ, Ansell SM, Kim WS, Gallamini A, Younes A, Alekseev S, Illés Á, Picardi M, Lech-Maranda E, Oki Y, Feldman T, Smolewski P, Savage KJ, Bartlett NL, Walewski J, Chen R, Ramchandren R, Zinzani PL, Cunningham D, Rosta A, Josephson NC, Song E, Sachs J, Liu R, Jolin HA, Huebner D, Radford J; ECHELON-1 Study Group.

N Engl J Med. 2018 Jan 25;378(4):331-344. doi: 10.1056/NEJMoa1708984. Epub 2017 Dec 10. Erratum in: N Engl J Med. 2018 Mar 1;378(9):878.

11.

Secondary CNS relapse in diffuse large B-cell lymphoma: defining high-risk patients and optimization of prophylaxis strategies.

Savage KJ.

Hematology Am Soc Hematol Educ Program. 2017 Dec 8;2017(1):578-586. doi: 10.1182/asheducation-2017.1.578. Review.

PMID:
29222307
12.

GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.

Savage K, Firth J, Stough C, Sarris J.

Phytother Res. 2018 Jan;32(1):3-18. doi: 10.1002/ptr.5940. Epub 2017 Nov 23. Review.

PMID:
29168225
13.

The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export.

Vohhodina J, Barros EM, Savage AL, Liberante FG, Manti L, Bankhead P, Cosgrove N, Madden AF, Harkin DP, Savage KI.

Nucleic Acids Res. 2017 Dec 15;45(22):12816-12833. doi: 10.1093/nar/gkx1046.

14.

Exogenous factors matter when interpreting the results of an impact evaluation: a case study of rainfall and child health programme intervention in Rwanda.

Mukabutera A, Thomson DR, Hedt-Gauthier BL, Atwood S, Basinga P, Nyirazinyoye L, Savage KP, Habimana M, Murray M.

Trop Med Int Health. 2017 Dec;22(12):1505-1513. doi: 10.1111/tmi.12995. Epub 2017 Nov 9.

PMID:
29080285
15.

International Assessment of Event-Free Survival at 24 Months and Subsequent Survival in Peripheral T-Cell Lymphoma.

Maurer MJ, Ellin F, Srour L, Jerkeman M, Bennani NN, Connors JM, Slack GW, Smedby KE, Ansell SM, Link BK, Cerhan JR, Relander T, Savage KJ, Feldman AL.

J Clin Oncol. 2017 Dec 20;35(36):4019-4026. doi: 10.1200/JCO.2017.73.8195. Epub 2017 Oct 26.

PMID:
29072976
16.

Effects of physical exercise in older adults with reduced physical capacity: meta-analysis of resistance exercise and multimodal exercise.

Liu CJ, Chang WP, Araujo de Carvalho I, Savage KEL, Radford LW, Amuthavalli Thiyagarajan J.

Int J Rehabil Res. 2017 Dec;40(4):303-314. doi: 10.1097/MRR.0000000000000249.

PMID:
29023317
17.

Observation as the initial management strategy in patients with mantle cell lymphoma.

Abrisqueta P, Scott DW, Slack GW, Steidl C, Mottok A, Gascoyne RD, Connors JM, Sehn LH, Savage KJ, Gerrie AS, Villa D.

Ann Oncol. 2017 Oct 1;28(10):2489-2495. doi: 10.1093/annonc/mdx333.

PMID:
28961827
18.

Prognostic Model to Predict Post-Autologous Stem-Cell Transplantation Outcomes in Classical Hodgkin Lymphoma.

Chan FC, Mottok A, Gerrie AS, Power M, Nijland M, Diepstra A, van den Berg A, Kamper P, d'Amore F, d'Amore AL, Hamilton-Dutoit S, Savage KJ, Shah SP, Connors JM, Gascoyne RD, Scott DW, Steidl C.

J Clin Oncol. 2017 Nov 10;35(32):3722-3733. doi: 10.1200/JCO.2017.72.7925. Epub 2017 Sep 12.

PMID:
28898161
19.

MHRA alert about Nexplanon migration.

Savage K, Menon K.

J Fam Plann Reprod Health Care. 2017 Oct;43(4):345. doi: 10.1136/jfprhc-2017-101881. Epub 2017 Aug 23. No abstract available.

PMID:
28835452
20.

Effects of Vitamin D Supplementation on Serum 25-Hydroxyvitamin D Concentrations and Physical Performance in Athletes: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Farrokhyar F, Sivakumar G, Savage K, Koziarz A, Jamshidi S, Ayeni OR, Peterson D, Bhandari M.

Sports Med. 2017 Nov;47(11):2323-2339. doi: 10.1007/s40279-017-0749-4. Review.

PMID:
28577257
21.

Knowledge, diagnosis and management of dentine hypersensitivity: a national survey of dentists in Nigeria.

Oderinu OH, Sede MA, Oginni AO, Adegbulugbe IC, Uti OG, Olusile AO, Udoye CI, Savage KO.

Int Dent J. 2017 Oct;67(5):287-293. doi: 10.1111/idj.12302. Epub 2017 May 20.

PMID:
28542892
22.

Analysis of surgical and MRI factors associated with cerebellar mutism.

Sergeant A, Kameda-Smith MM, Manoranjan B, Karmur B, Duckworth J, Petrelli T, Savage K, Ajani O, Yarascavitch B, Samaan MC, Scheinemann K, Alyman C, Almenawer S, Farrokhyar F, Fleming AJ, Singh SK, Stein N.

J Neurooncol. 2017 Jul;133(3):539-552. doi: 10.1007/s11060-017-2462-4. Epub 2017 May 19.

PMID:
28527006
23.

Salvage chemotherapy and autologous stem cell transplantation for peripheral T-cell lymphoma: a subset analysis of the Canadian Cancer Trials Group LY.12 randomized phase 3 study.

Skamene T, Crump M, Savage KJ, Reiman T, Kuruvilla J, Good D, LeBrun D, Meyer RM, Sehn LH, Soulières D, Stakiw J, Laferriere N, Luminari S, Shepherd LE, Djurfeldt M, Zhu L, Chen BE, Hay AE.

Leuk Lymphoma. 2017 Oct;58(10):2319-2327. doi: 10.1080/10428194.2017.1312379. Epub 2017 May 15.

PMID:
28504033
24.

Genetic profiling of MYC and BCL2 in diffuse large B-cell lymphoma determines cell-of-origin-specific clinical impact.

Ennishi D, Mottok A, Ben-Neriah S, Shulha HP, Farinha P, Chan FC, Meissner B, Boyle M, Hother C, Kridel R, Lai D, Saberi S, Bashashati A, Shah SP, Morin RD, Marra MA, Savage KJ, Sehn LH, Steidl C, Connors JM, Gascoyne RD, Scott DW.

Blood. 2017 May 18;129(20):2760-2770. doi: 10.1182/blood-2016-11-747022. Epub 2017 Mar 28.

PMID:
28351934
25.

Peripheral T-Cell Lymphoma, Not Otherwise Specified: A Review of Current Disease Understanding and Therapeutic Approaches.

Al-Zahrani M, Savage KJ.

Hematol Oncol Clin North Am. 2017 Apr;31(2):189-207. doi: 10.1016/j.hoc.2016.11.009. Review.

PMID:
28340873
26.

ABVD chemotherapy with reduced radiation therapy rates in children, adolescents and young adults with all stages of Hodgkin lymphoma.

Marr KC, Connors JM, Savage KJ, Goddard KJ, Deyell RJ.

Ann Oncol. 2017 Apr 1;28(4):849-854. doi: 10.1093/annonc/mdx005.

27.

The number of extranodal sites assessed by PET/CT scan is a powerful predictor of CNS relapse for patients with diffuse large B-cell lymphoma: An international multicenter study of 1532 patients treated with chemoimmunotherapy.

El-Galaly TC, Villa D, Michaelsen TY, Hutchings M, Mikhaeel NG, Savage KJ, Sehn LH, Barrington S, Hansen JW, Smith D, Rady K, Mylam KJ, Larsen TS, Holmberg S, Juul MB, Cordua S, Clausen MR, Jensen KB, Johnsen HE, Seymour JF, Connors JM, de Nully Brown P, Bøgsted M, Cheah CY.

Eur J Cancer. 2017 Apr;75:195-203. doi: 10.1016/j.ejca.2016.12.029. Epub 2017 Feb 23.

PMID:
28237865
28.

Ventricular arrhythmias and sudden death in patients taking ibrutinib.

Lampson BL, Yu L, Glynn RJ, Barrientos JC, Jacobsen ED, Banerji V, Jones JA, Walewska R, Savage KJ, Michaud GF, Moslehi JJ, Brown JR.

Blood. 2017 May 4;129(18):2581-2584. doi: 10.1182/blood-2016-10-742437. Epub 2017 Feb 21. No abstract available.

PMID:
28223277
29.

Efficacy and Safety of Nivolumab Alone or in Combination With Ipilimumab in Patients With Mucosal Melanoma: A Pooled Analysis.

D'Angelo SP, Larkin J, Sosman JA, Lebbé C, Brady B, Neyns B, Schmidt H, Hassel JC, Hodi FS, Lorigan P, Savage KJ, Miller WH Jr, Mohr P, Marquez-Rodas I, Charles J, Kaatz M, Sznol M, Weber JS, Shoushtari AN, Ruisi M, Jiang J, Wolchok JD.

J Clin Oncol. 2017 Jan 10;35(2):226-235. Epub 2016 Nov 7.

30.

Defining the clonality of peripheral T cell lymphomas using RNA-seq.

Brown SD, Hapgood G, Steidl C, Weng AP, Savage KJ, Holt RA.

Bioinformatics. 2017 Apr 15;33(8):1111-1115. doi: 10.1093/bioinformatics/btw810.

31.

Secondary Breast Cancer Risk by Radiation Volume in Women With Hodgkin Lymphoma.

Conway JL, Connors JM, Tyldesley S, Savage KJ, Campbell BA, Zheng YY, Hamm J, Pickles T.

Int J Radiat Oncol Biol Phys. 2017 Jan 1;97(1):35-41. doi: 10.1016/j.ijrobp.2016.10.004. Epub 2016 Oct 13.

PMID:
27979454
32.

Central Nervous System Prophylaxis for Aggressive B-cell Lymphoma: Who, What, and When?

Schmitz N, Nickelsen M, Savage KJ.

Hematol Oncol Clin North Am. 2016 Dec;30(6):1277-1291. doi: 10.1016/j.hoc.2016.07.008. Review.

PMID:
27888881
33.

Brentuximab vedotin activity in diffuse large B-cell lymphoma with CD30 undetectable by visual assessment of conventional immunohistochemistry.

Bartlett NL, Smith MR, Siddiqi T, Advani RH, O'Connor OA, Sharman JP, Feldman T, Savage KJ, Shustov AR, Diefenbach CS, Oki Y, Palanca-Wessels MC, Uttarwar M, Li M, Yang J, Jacobsen ED.

Leuk Lymphoma. 2017 Jul;58(7):1607-1616. doi: 10.1080/10428194.2016.1256481. Epub 2016 Nov 20.

PMID:
27868471
34.

Vitamin D supplementation affects the IGF system in men after acute exercise.

Darr RL, Savage KJ, Baker M, Wilding GE, Raswalsky A, Rideout T, Browne RW, Horvath PJ.

Growth Horm IGF Res. 2016 Oct - Dec;30-31:45-51. doi: 10.1016/j.ghir.2016.11.002. Epub 2016 Nov 5.

PMID:
27863277
35.

Nivolumab in the Treatment of Refractory Pediatric Hodgkin Lymphoma.

Foran AE, Nadel HR, Lee AF, Savage KJ, Deyell RJ.

J Pediatr Hematol Oncol. 2017 Jul;39(5):e263-e266. doi: 10.1097/MPH.0000000000000703.

PMID:
27841828
36.

Immune checkpoint inhibitors in Hodgkin and non-Hodgkin lymphoma: how they work and when to use them.

Savage KJ, Steidl C.

Expert Rev Hematol. 2016 Nov;9(11):1007-1009. Epub 2016 Oct 17. No abstract available.

PMID:
27677541
37.

Outcome of primary cutaneous anaplastic large cell lymphoma: a 20-year British Columbia Cancer Agency experience.

Hapgood G, Pickles T, Sehn LH, Villa D, Klasa R, Scott DW, Gerrie AS, Gascoyne RD, Slack GW, Parsons C, Morris JW, Connors JM, Savage KJ.

Br J Haematol. 2017 Jan;176(2):234-240. doi: 10.1111/bjh.14404. Epub 2016 Oct 21.

PMID:
27766622
38.

Diffuse large B-cell lymphoma with testicular involvement: outcome and risk of CNS relapse in the rituximab era.

Kridel R, Telio D, Villa D, Sehn LH, Gerrie AS, Shenkier T, Klasa R, Slack GW, Tan K, Gascoyne RD, Connors JM, Savage KJ.

Br J Haematol. 2017 Jan;176(2):210-221. doi: 10.1111/bjh.14392. Epub 2016 Oct 14.

PMID:
27739058
39.

Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer.

Parkes EE, Walker SM, Taggart LE, McCabe N, Knight LA, Wilkinson R, McCloskey KD, Buckley NE, Savage KI, Salto-Tellez M, McQuaid S, Harte MT, Mullan PB, Harkin DP, Kennedy RD.

J Natl Cancer Inst. 2016 Oct 5;109(1). pii: djw199. Print 2017 Jan.

40.

Uterine, but not ovarian, female reproductive organ involvement at presentation by diffuse large B-cell lymphoma is associated with poor outcomes and a high frequency of secondary CNS involvement.

El-Galaly TC, Cheah CY, Hutchings M, Mikhaeel NG, Savage KJ, Sehn LH, Barrington S, Hansen JW, Poulsen MØ, Smith D, Rady K, Mylam KJ, Larsen TS, Holmberg S, Juul MB, Cordua S, Clausen MR, Jensen KB, Bøgsted M, Johnsen HE, Seymour JF, Connors JM, Brown PD, Villa D.

Br J Haematol. 2016 Dec;175(5):876-883. doi: 10.1111/bjh.14325. Epub 2016 Sep 29.

PMID:
27681999
41.

Leukocytoclastic vasculitis following lenalidomide during the treatment of follicular lymphoma.

Loree JM, Cai E, Sheffield BS, Dutz JP, Villa D, Shepherd LE, Connors JM, Sehn LH, Savage KJ.

Leuk Lymphoma. 2017 Mar;58(3):711-714. doi: 10.1080/10428194.2016.1204657. Epub 2016 Aug 25. No abstract available.

PMID:
27557805
42.

Neurogenic Fever after Acute Traumatic Spinal Cord Injury: A Qualitative Systematic Review.

Savage KE, Oleson CV, Schroeder GD, Sidhu GS, Vaccaro AR.

Global Spine J. 2016 Sep;6(6):607-14. doi: 10.1055/s-0035-1570751. Epub 2016 Jan 30. Review.

43.

Nodular lymphocyte-predominant Hodgkin lymphoma.

Savage KJ, Mottok A, Fanale M.

Semin Hematol. 2016 Jul;53(3):190-202. doi: 10.1053/j.seminhematol.2016.05.009. Epub 2016 May 13. Review.

PMID:
27496311
44.

Rainfall variation and child health: effect of rainfall on diarrhea among under 5 children in Rwanda, 2010.

Mukabutera A, Thomson D, Murray M, Basinga P, Nyirazinyoye L, Atwood S, Savage KP, Ngirimana A, Hedt-Gauthier BL.

BMC Public Health. 2016 Aug 5;16:731. doi: 10.1186/s12889-016-3435-9.

45.

Maintenance rituximab following induction R-CHOP chemotherapy in patients with composite or discordant, indolent and aggressive, B-cell non-Hodgkin lymphomas.

Kansara R, Connors JM, Savage KJ, Gerrie AS, Scott DW, Slack GW, Gascoyne RD, Sehn LH, Villa D.

Haematologica. 2016 Oct;101(10):e411-e414. Epub 2016 Jun 16. No abstract available.

46.

Nivolumab for classical Hodgkin's lymphoma after failure of both autologous stem-cell transplantation and brentuximab vedotin: a multicentre, multicohort, single-arm phase 2 trial.

Younes A, Santoro A, Shipp M, Zinzani PL, Timmerman JM, Ansell S, Armand P, Fanale M, Ratanatharathorn V, Kuruvilla J, Cohen JB, Collins G, Savage KJ, Trneny M, Kato K, Farsaci B, Parker SM, Rodig S, Roemer MG, Ligon AH, Engert A.

Lancet Oncol. 2016 Sep;17(9):1283-94. doi: 10.1016/S1470-2045(16)30167-X. Epub 2016 Jul 20.

47.

Site of central nervous system (CNS) relapse in patients with diffuse large B-cell lymphoma (DLBCL) by the CNS-IPI risk model.

Kansara R, Villa D, Gerrie AS, Klasa R, Shenkier T, Scott DW, Slack GW, Gascoyne RD, Connors JM, Sehn LH, Savage KJ.

Br J Haematol. 2017 Nov;179(3):508-510. doi: 10.1111/bjh.14229. Epub 2016 Jul 22. No abstract available.

PMID:
27443424
48.

Five-year survival and durability results of brentuximab vedotin in patients with relapsed or refractory Hodgkin lymphoma.

Chen R, Gopal AK, Smith SE, Ansell SM, Rosenblatt JD, Savage KJ, Connors JM, Engert A, Larsen EK, Huebner D, Fong A, Younes A.

Blood. 2016 Sep 22;128(12):1562-6. doi: 10.1182/blood-2016-02-699850. Epub 2016 Jul 18.

49.

Effect of nivolumab on health-related quality of life in patients with treatment-naïve advanced melanoma: results from the phase III CheckMate 066 study.

Long GV, Atkinson V, Ascierto PA, Robert C, Hassel JC, Rutkowski P, Savage KJ, Taylor F, Coon C, Gilloteau I, Dastani HB, Waxman IM, Abernethy AP.

Ann Oncol. 2016 Oct;27(10):1940-6. doi: 10.1093/annonc/mdw265. Epub 2016 Jul 12.

50.

CNS International Prognostic Index: A Risk Model for CNS Relapse in Patients With Diffuse Large B-Cell Lymphoma Treated With R-CHOP.

Schmitz N, Zeynalova S, Nickelsen M, Kansara R, Villa D, Sehn LH, Glass B, Scott DW, Gascoyne RD, Connors JM, Ziepert M, Pfreundschuh M, Loeffler M, Savage KJ.

J Clin Oncol. 2016 Sep 10;34(26):3150-6. doi: 10.1200/JCO.2015.65.6520. Epub 2016 Jul 5.

PMID:
27382100

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