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ASB1 differential methylation in ischaemic cardiomyopathy: relationship with left ventricular performance in end-stage heart failure patients.

Ortega A, Tarazón E, Gil-Cayuela C, Martínez-Dolz L, Lago F, González-Juanatey JR, Sandoval J, Portolés M, Roselló-Lletí E, Rivera M.

ESC Heart Fail. 2018 Apr 17. doi: 10.1002/ehf2.12289. [Epub ahead of print]


A guideline update for the practice of echocardiography in the cardiac screening of sports participants: a joint policy statement from the British Society of Echocardiography and Cardiac Risk in the Young.

Oxborough D, Augustine D, Gati S, George K, Harkness A, Mathew T, Papadakis M, Ring L, Robinson S, Sandoval J, Sarwar R, Sharma S, Sharma V, Sheikh N, Somauroo J, Stout M, Willis J, Zaidi A.

Echo Res Pract. 2018 Mar;5(1):G1-G10. doi: 10.1530/ERP-17-0075.


Interventional Therapies in Pulmonary Hypertension.

Sandoval J.

Rev Esp Cardiol (Engl Ed). 2018 Mar 12. pii: S1885-5857(18)30036-7. doi: 10.1016/j.rec.2018.02.002. [Epub ahead of print] English, Spanish.


Evaluation of Potential Mechanisms Controlling the Catalase Expression in Breast Cancer Cells.

Glorieux C, Sandoval JM, Dejeans N, Nonckreman S, Bahloula K, Poirel HA, Calderon PB.

Oxid Med Cell Longev. 2018 Jan 28;2018:5351967. doi: 10.1155/2018/5351967. eCollection 2018.


Genetic ancestry of families of putative Inka descent.

Sandoval JR, Lacerda DR, Jota MS, Elward R, Acosta O, Pinedo D, Danos P, Cuellar C, Revollo S, Santos FR, Fujita R.

Mol Genet Genomics. 2018 Mar 3. doi: 10.1007/s00438-018-1427-4. [Epub ahead of print]


Epigenomic signature of adrenoleukodystrophy predicts compromised oligodendrocyte differentiation.

Schlüter A, Sandoval J, Fourcade S, Díaz-Lagares A, Ruiz M, Casaccia P, Esteller M, Pujol A.

Brain Pathol. 2018 Feb 24. doi: 10.1111/bpa.12595. [Epub ahead of print]


High contiguity Arabidopsis thaliana genome assembly with a single nanopore flow cell.

Michael TP, Jupe F, Bemm F, Motley ST, Sandoval JP, Lanz C, Loudet O, Weigel D, Ecker JR.

Nat Commun. 2018 Feb 7;9(1):541. doi: 10.1038/s41467-018-03016-2.


Improved Total Synthesis of Tubulysins and Design, Synthesis, and Biological Evaluation of New Tubulysins with Highly Potent Cytotoxicities against Cancer Cells as Potential Payloads for Antibody-Drug Conjugates.

Nicolaou KC, Erande RD, Yin J, Vourloumis D, Aujay M, Sandoval J, Munneke S, Gavrilyuk J.

J Am Chem Soc. 2018 Mar 14;140(10):3690-3711. doi: 10.1021/jacs.7b12692. Epub 2018 Jan 30.


Public smoking ban and socioeconomic inequalities in smoking prevalence and cessation: a cross-sectional population-based study in Geneva, Switzerland (1995-2014).

Sandoval JL, Leão T, Cullati S, Theler JM, Joost S, Humair JP, Gaspoz JM, Guessous I.

Tob Control. 2018 Jan 26. pii: tobaccocontrol-2017-053986. doi: 10.1136/tobaccocontrol-2017-053986. [Epub ahead of print]


Epigenetic control of influenza virus: role of H3K79 methylation in interferon-induced antiviral response.

Marcos-Villar L, Díaz-Colunga J, Sandoval J, Zamarreño N, Landeras-Bueno S, Esteller M, Falcón A, Nieto A.

Sci Rep. 2018 Jan 19;8(1):1230. doi: 10.1038/s41598-018-19370-6.


Maternal educational level and the risk of persistent post-partum glucose metabolism disorders in women with gestational diabetes mellitus.

Gante I, Ferreira AC, Pestana G, Pires D, Amaral N, Dores J, do Céu Almeida M, Sandoval JL.

Acta Diabetol. 2018 Mar;55(3):243-251. doi: 10.1007/s00592-017-1090-y. Epub 2017 Dec 29.


Enclaves of genetic diversity resisted Inca impacts on population history.

Barbieri C, Sandoval JR, Valqui J, Shimelman A, Ziemendorff S, Schröder R, Geppert M, Roewer L, Gray R, Stoneking M, Fujita R, Heggarty P.

Sci Rep. 2017 Dec 12;7(1):17411. doi: 10.1038/s41598-017-17728-w.


MGIS: managing banana (Musa spp.) genetic resources information and high-throughput genotyping data.

Ruas M, Guignon V, Sempere G, Sardos J, Hueber Y, Duvergey H, Andrieu A, Chase R, Jenny C, Hazekamp T, Irish B, Jelali K, Adeka J, Ayala-Silva T, Chao CP, Daniells J, Dowiya B, Effa Effa B, Gueco L, Herradura L, Ibobondji L, Kempenaers E, Kilangi J, Muhangi S, Ngo Xuan P, Paofa J, Pavis C, Thiemele D, Tossou C, Sandoval J, Sutanto A, Vangu Paka G, Yi G, Van den Houwe I, Roux N, Rouard M.

Database (Oxford). 2017 Jan 1;2017. doi: 10.1093/database/bax046.


Improving bone health in men with prostate cancer receiving androgen deprivation therapy: Results of a randomized phase 2 trial.

Alibhai SMH, Breunis H, Timilshina N, Hamidi MS, Cheung AM, Tomlinson GA, Manokumar T, Samadi O, Sandoval J, Durbano S, Warde P, Jones JM.

Cancer. 2018 Mar 15;124(6):1132-1140. doi: 10.1002/cncr.31171. Epub 2017 Dec 6.


Dirofilaria immitis JYD-34 isolate: whole genome analysis.

Bourguinat C, Lefebvre F, Sandoval J, Bondesen B, Moreno Y, Prichard RK.

Parasit Vectors. 2017 Nov 9;10(Suppl 2):494. doi: 10.1186/s13071-017-2437-5.


CD137 (4-1BB) Costimulation Modifies DNA Methylation in CD8+ T Cell-Relevant Genes.

Aznar MA, Labiano S, Diaz-Lagares A, Molina C, Garasa S, Azpilikueta A, Etxeberria I, Sanchez-Paulete AR, Korman AJ, Esteller M, Sandoval J, Melero I.

Cancer Immunol Res. 2018 Jan;6(1):69-78. doi: 10.1158/2326-6066.CIR-17-0159. Epub 2017 Nov 13.


Aortic Stent Implantation Using Live 3-Dimensional Image Fusion Guidance.

Sandoval JP, Aristizabal G, Zabal-Cerdeira C.

Rev Esp Cardiol (Engl Ed). 2017 Nov 7. pii: S1885-5857(17)30478-4. doi: 10.1016/j.rec.2017.10.012. [Epub ahead of print] English, Spanish. No abstract available.


Streamlined Total Synthesis of Trioxacarcins and Its Application to the Design, Synthesis, and Biological Evaluation of Analogues Thereof. Discovery of Simpler Designed and Potent Trioxacarcin Analogues.

Nicolaou KC, Chen P, Zhu S, Cai Q, Erande RD, Li R, Sun H, Pulukuri KK, Rigol S, Aujay M, Sandoval J, Gavrilyuk J.

J Am Chem Soc. 2017 Nov 1;139(43):15467-15478. doi: 10.1021/jacs.7b08820. Epub 2017 Oct 20.


In-bag enzymatic splenic digestion: a novel alternative to manual morcellation?

Villarreal ED, Hewgley WP, Lang WH, Morton CL, Mao S, Wu J, Sandoval JA.

J Surg Res. 2017 Oct;218:209-216. doi: 10.1016/j.jss.2017.05.060. Epub 2017 Jun 21.


Return to work and work-related disability among AML survivors.

Samadi O, Breunis H, Sandoval J, Akilan K, Timilshina N, Alibhai SMH.

Ann Hematol. 2017 Oct;96(10):1625-1633. doi: 10.1007/s00277-017-3097-4. Epub 2017 Aug 14.


Epigenetics and Oxidative Stress in Aging.

Guillaumet-Adkins A, Yañez Y, Peris-Diaz MD, Calabria I, Palanca-Ballester C, Sandoval J.

Oxid Med Cell Longev. 2017;2017:9175806. doi: 10.1155/2017/9175806. Epub 2017 Jul 20. Review.


Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex.

Luo C, Keown CL, Kurihara L, Zhou J, He Y, Li J, Castanon R, Lucero J, Nery JR, Sandoval JP, Bui B, Sejnowski TJ, Harkins TT, Mukamel EA, Behrens MM, Ecker JR.

Science. 2017 Aug 11;357(6351):600-604. doi: 10.1126/science.aan3351.


Introduction of an organised programme and social inequalities in mammography screening: A 22-year population-based study in Geneva, Switzerland.

Sandoval JL, Theler JM, Cullati S, Bouchardy C, Manor O, Gaspoz JM, Guessous I.

Prev Med. 2017 Oct;103:49-55. doi: 10.1016/j.ypmed.2017.07.025. Epub 2017 Aug 1.


Translating cancer epigenomics into the clinic: focus on lung cancer.

Mari-Alexandre J, Diaz-Lagares A, Villalba M, Juan O, Crujeiras AB, Calvo A, Sandoval J.

Transl Res. 2017 Nov;189:76-92. doi: 10.1016/j.trsl.2017.05.008. Epub 2017 Jun 2. Review.


Massive aortic root aneurysm in an infant with the Loeys-Dietz syndrome.

Molina-Sánchez T, Calderón-Colmenero J, Sandoval JP.

Cardiol Young. 2017 Aug;27(6):1219-1220. doi: 10.1017/S1047951117001056. Epub 2017 Jun 13.


Diagnosis and assessment of dilated cardiomyopathy: a guideline protocol from the British Society of Echocardiography.

Mathew T, Williams L, Navaratnam G, Rana B, Wheeler R, Collins K, Harkness A, Jones R, Knight D, O'Gallagher K, Oxborough D, Ring L, Sandoval J, Stout M, Sharma V, Steeds RP; British Society of Echocardiography Education Committee.

Echo Res Pract. 2017 Jun;4(2):G1-G13. doi: 10.1530/ERP-16-0037.


Thyroid hormone biosynthesis machinery is altered in the ischemic myocardium: An epigenomic study.

Gil-Cayuela C, Roselló-LLetí E, Tarazón E, Ortega A, Sandoval J, Martínez-Dolz L, Cinca J, Jorge E, González-Juanatey JR, Lago F, Rivera M, Portolés M.

Int J Cardiol. 2017 Sep 15;243:27-33. doi: 10.1016/j.ijcard.2017.05.042. Epub 2017 May 11.


12,13-Aziridinyl Epothilones. Stereoselective Synthesis of Trisubstituted Olefinic Bonds from Methyl Ketones and Heteroaromatic Phosphonates and Design, Synthesis, and Biological Evaluation of Potent Antitumor Agents.

Nicolaou KC, Rhoades D, Wang Y, Bai R, Hamel E, Aujay M, Sandoval J, Gavrilyuk J.

J Am Chem Soc. 2017 May 31;139(21):7318-7334. doi: 10.1021/jacs.7b02655. Epub 2017 May 17.


Compression Ratio Ion Mobility Programming (CRIMP) Accumulation and Compression of Billions of Ions for Ion Mobility-Mass Spectrometry Using Traveling Waves in Structures for Lossless Ion Manipulations (SLIM).

Deng L, Garimella SVB, Hamid AM, Webb IK, Attah IK, Norheim RV, Prost SA, Zheng X, Sandoval JA, Baker ES, Ibrahim YM, Smith RD.

Anal Chem. 2017 Jun 20;89(12):6432-6439. doi: 10.1021/acs.analchem.7b00189. Epub 2017 May 25.


Molecular-Subtype-Specific Biomarkers Improve Prediction of Prognosis in Colorectal Cancer.

Bramsen JB, Rasmussen MH, Ongen H, Mattesen TB, Ørntoft MW, Árnadóttir SS, Sandoval J, Laguna T, Vang S, Øster B, Lamy P, Madsen MR, Laurberg S, Esteller M, Dermitzakis ET, Ørntoft TF, Andersen CL.

Cell Rep. 2017 May 9;19(6):1268-1280. doi: 10.1016/j.celrep.2017.04.045.


Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer.

Sharma SK, Pourat J, Abdel-Atti D, Carlin SD, Piersigilli A, Bankovich AJ, Gardner EE, Hamdy O, Isse K, Bheddah S, Sandoval J, Cunanan KM, Johansen EB, Allaj V, Sisodiya V, Liu D, Zeglis BM, Rudin CM, Dylla SJ, Poirier JT, Lewis JS.

Cancer Res. 2017 Jul 15;77(14):3931-3941. doi: 10.1158/0008-5472.CAN-17-0299. Epub 2017 May 9.


A tale of agriculturalists and hunter-gatherers: Exploring the thrifty genotype hypothesis in native South Americans.

Reales G, Rovaris DL, Jacovas VC, Hünemeier T, Sandoval JR, Salazar-Granara A, Demarchi DA, Tarazona-Santos E, Felkl AB, Serafini MA, Salzano FM, Bisso-Machado R, Comas D, Paixão-Côrtes VR, Bortolini MC.

Am J Phys Anthropol. 2017 Jul;163(3):591-601. doi: 10.1002/ajpa.23233. Epub 2017 May 2.


Obesity and menopause modify the epigenomic profile of breast cancer.

Crujeiras AB, Diaz-Lagares A, Stefansson OA, Macias-Gonzalez M, Sandoval J, Cueva J, Lopez-Lopez R, Moran S, Jonasson JG, Tryggvadottir L, Olafsdottir E, Tinahones FJ, Carreira MC, Casanueva FF, Esteller M.

Endocr Relat Cancer. 2017 Jul;24(7):351-363. doi: 10.1530/ERC-16-0565. Epub 2017 Apr 25.


[On the Future of Portuguese Physician-Scientists].

Azevedo Soares C, Incio J, Reis Ferreira M, Barbosa-Breda J, Páris L, Sandoval JL.

Acta Med Port. 2016 Dec 30;29(12):793-795. doi: 10.20344/amp.8388. Epub 2016 Dec 30. Portuguese. No abstract available.


Dehydration Causes Increased Reliance on Protein Oxidation in Mice: A Test of the Protein-for-Water Hypothesis in a Mammal.

McCue MD, Sandoval J, Beltran J, Gerson AR.

Physiol Biochem Zool. 2017 May/Jun;90(3):359-369. doi: 10.1086/690912. Epub 2017 Feb 8.


Endocardial Pacing in Infants and Young Children Weighing Less Than 10 Kilograms.

Campos-Quintero A, García-Montes JA, Cruz-Arias R, Zabal-Cerdeira C, Calderón-Colmenero J, Sandoval JP.

Rev Esp Cardiol (Engl Ed). 2018 Jan;71(1):48-51. doi: 10.1016/j.rec.2017.02.036. Epub 2017 Mar 23. English, Spanish. No abstract available.


Serpentine Ultralong Path with Extended Routing (SUPER) High Resolution Traveling Wave Ion Mobility-MS using Structures for Lossless Ion Manipulations.

Deng L, Webb IK, Garimella SVB, Hamid AM, Zheng X, Norheim RV, Prost SA, Anderson GA, Sandoval JA, Baker ES, Ibrahim YM, Smith RD.

Anal Chem. 2017 Apr 18;89(8):4628-4634. doi: 10.1021/acs.analchem.7b00185. Epub 2017 Apr 5.


DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patients.

Crujeiras AB, Diaz-Lagares A, Sandoval J, Milagro FI, Navas-Carretero S, Carreira MC, Gomez A, Hervas D, Monteiro MP, Casanueva FF, Esteller M, Martinez JA.

Sci Rep. 2017 Feb 17;7:41903. doi: 10.1038/srep41903.


Prognostic Implications of Serum Albumin Levels in Patients With Acute Coronary Syndromes.

González-Pacheco H, Amezcua-Guerra LM, Sandoval J, Martínez-Sánchez C, Ortiz-León XA, Peña-Cabral MA, Bojalil R.

Am J Cardiol. 2017 Apr 1;119(7):951-958. doi: 10.1016/j.amjcard.2016.11.054. Epub 2017 Jan 5.


Whole genome grey and white matter DNA methylation profiles in dorsolateral prefrontal cortex.

Sanchez-Mut JV, Heyn H, Vidal E, Delgado-Morales R, Moran S, Sayols S, Sandoval J, Ferrer I, Esteller M, Gräff J.

Synapse. 2017 Jun;71(6). doi: 10.1002/syn.21959. Epub 2017 Feb 6.


Operative and Immediate Postoperative Differences Between Traditional Multiport and Reduced Port Laparoscopic Total Splenectomy in Pediatric Patients.

Seims AD, VanHouwelingen L, Mead J, Mao S, Loh A, Sandoval JA, Davidoff AM, Wu J, Wang WC, Fernandez-Pineda I.

J Laparoendosc Adv Surg Tech A. 2017 Feb;27(2):206-210. doi: 10.1089/lap.2016.0309. Epub 2016 Oct 24.


Right Ventricular Outflow Tract Stenting in Tetralogy of Fallot Infants With Risk Factors for Early Primary Repair.

Sandoval JP, Chaturvedi RR, Benson L, Morgan G, Van Arsdell G, Honjo O, Caldarone C, Lee KJ.

Circ Cardiovasc Interv. 2016 Dec;9(12). pii: e003979.


Perceptions of Study Newsletters for Older Cancer Patients in Longitudinal Studies.

Mohamedali M, Sandoval J, Thiruvarooran V, Stacey H, O'Neill M, Breunis H, Timilshina N, Durbano S, Alibhai SMH.

J Cancer Educ. 2018 Apr;33(2):463-469. doi: 10.1007/s13187-016-1143-x.


Neutral hydrophilic coatings for capillary electrophoresis prepared by controlled radical polymerization.

Navarro FH, Gómez JE, Espinal JH, Sandoval JE.

Anal Chim Acta. 2016 Dec 15;948:104-112. doi: 10.1016/j.aca.2016.10.023. Epub 2016 Oct 19.


Persistent pulmonary hypertension and right ventricular function after percutaneous mechanical thrombectomy in severe acute pulmonary embolism.

Eid-Lidt G, Gaspar J, Sandoval J, Gonzalez-Pacheco H, Arias A, Acevedo P, Pulido T, Martinez-Sanchez C, Martinez-Rios MA.

Eur Respir J. 2017 Jan 11;49(1). pii: 1600910. doi: 10.1183/13993003.00910-2016. Print 2017 Jan. No abstract available.


Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer.

Diaz-Lagares A, Crujeiras AB, Lopez-Serra P, Soler M, Setien F, Goyal A, Sandoval J, Hashimoto Y, Martinez-Cardús A, Gomez A, Heyn H, Moutinho C, Espada J, Vidal A, Paúles M, Galán M, Sala N, Akiyama Y, Martínez-Iniesta M, Farré L, Villanueva A, Gross M, Diederichs S, Guil S, Esteller M.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7535-E7544. Epub 2016 Nov 7.


Corrigendum: A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect.

Lopez-Serra P, Marcilla M, Villanueva A, Ramos-Fernandez A, Palau A, Leal L, Wahi JE, Setien-Baranda F, Szczesna K, Moutinho C, Martinez-Cardus A, Heyn H, Sandoval J, Puertas S, Vidal A, Sanjuan X, Martinez-Balibrea E, Viñals F, Perales JC, Bramsem JB, Ørntoft TF, Andersen CL, Tabernero J, McDermott U, Boxer MB, Vander Heiden MG, Albar JP, Esteller M.

Nat Commun. 2016 Nov 2;7:13467. doi: 10.1038/ncomms13467. No abstract available.


Epigenetic Regulation of Early- and Late-Response Genes in Acute Pancreatitis.

Sandoval J, Pereda J, Pérez S, Finamor I, Vallet-Sánchez A, Rodríguez JL, Franco L, Sastre J, López-Rodas G.

J Immunol. 2016 Nov 15;197(10):4137-4150. Epub 2016 Oct 19.


Chromatin remodeling regulates catalase expression during cancer cells adaptation to chronic oxidative stress.

Glorieux C, Sandoval JM, Fattaccioli A, Dejeans N, Garbe JC, Dieu M, Verrax J, Renard P, Huang P, Calderon PB.

Free Radic Biol Med. 2016 Oct;99:436-450. doi: 10.1016/j.freeradbiomed.2016.08.031. Epub 2016 Aug 31.


Catheter-Based Palliation in an Infant With Obstructed Cor Triatriatum.

Khoury M, Sandoval JP, Grosse-Wortmann L, Jaeggi E, Chaturvedi RR.

Can J Cardiol. 2016 Dec;32(12):1575.e13-1575.e15. doi: 10.1016/j.cjca.2016.07.003. Epub 2016 Jul 15.


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