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Items: 47


Genome-wide identification of Grainy head targets in Drosophila reveals regulatory interactions with the POU domain transcription factor Vvl.

Yao L, Wang S, Westholm JO, Dai Q, Matsuda R, Hosono C, Bray S, Lai EC, Samakovlis C.

Development. 2017 Sep 1;144(17):3145-3155. doi: 10.1242/dev.143297. Epub 2017 Jul 31.


Multipotent versus differentiated cell fate selection in the developing Drosophila airways.

Matsuda R, Hosono C, Samakovlis C, Saigo K.

Elife. 2015 Dec 2;4. pii: e09646. doi: 10.7554/eLife.09646.


Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes.

Hosono C, Matsuda R, Adryan B, Samakovlis C.

Nat Cell Biol. 2015 Dec;17(12):1569-76. doi: 10.1038/ncb3267. Epub 2015 Nov 9.


The intersection of the extrinsic hedgehog and WNT/wingless signals with the intrinsic Hox code underpins branching pattern and tube shape diversity in the drosophila airways.

Matsuda R, Hosono C, Saigo K, Samakovlis C.

PLoS Genet. 2015 Jan 23;11(1):e1004929. doi: 10.1371/journal.pgen.1004929. eCollection 2015 Jan.


Src kinases and ERK activate distinct responses to Stitcher receptor tyrosine kinase signaling during wound healing in Drosophila.

Tsarouhas V, Yao L, Samakovlis C.

J Cell Sci. 2014 Apr 15;127(Pt 8):1829-39. doi: 10.1242/jcs.143016. Epub 2014 Feb 12.


Two-tiered control of epithelial growth and autophagy by the insulin receptor and the ret-like receptor, stitcher.

O'Farrell F, Wang S, Katheder N, Rusten TE, Samakovlis C.

PLoS Biol. 2013 Jul;11(7):e1001612. doi: 10.1371/journal.pbio.1001612. Epub 2013 Jul 23.


Control of airway tube diameter and integrity by secreted chitin-binding proteins in Drosophila.

Tiklová K, Tsarouhas V, Samakovlis C.

PLoS One. 2013 Jun 24;8(6):e67415. doi: 10.1371/journal.pone.0067415. Print 2013.


Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease.

Krauss-Etschmann S, Bush A, Bellusci S, Brusselle GG, Dahlén SE, Dehmel S, Eickelberg O, Gibson G, Hylkema MN, Knaus P, Königshoff M, Lloyd CM, Macciarini P, Mailleux A, Marsland BJ, Postma DS, Roberts G, Samakovlis C, Stocks J, Vandesompele J, Wjst M, Holloway J.

Thorax. 2013 Apr;68(4):380-4. doi: 10.1136/thoraxjnl-2012-201902. Epub 2012 Jul 10. Review.


Dimer formation via the homeodomain is required for function and specificity of Sex combs reduced in Drosophila.

Papadopoulos DK, Skouloudaki K, Adachi Y, Samakovlis C, Gehring WJ.

Dev Biol. 2012 Jul 1;367(1):78-89. doi: 10.1016/j.ydbio.2012.04.021. Epub 2012 Apr 28.


Grainy head and its target genes in epithelial morphogenesis and wound healing.

Wang S, Samakovlis C.

Curr Top Dev Biol. 2012;98:35-63. doi: 10.1016/B978-0-12-386499-4.00002-1. Review.


Epithelial septate junction assembly relies on melanotransferrin iron binding and endocytosis in Drosophila.

Tiklová K, Senti KA, Wang S, Gräslund A, Samakovlis C.

Nat Cell Biol. 2010 Nov;12(11):1071-7. doi: 10.1038/ncb2111. Epub 2010 Oct 10.


The Drosophila LEM-domain protein MAN1 antagonizes BMP signaling at the neuromuscular junction and the wing crossveins.

Wagner N, Weyhersmüller A, Blauth A, Schuhmann T, Heckmann M, Krohne G, Samakovlis C.

Dev Biol. 2010 Mar 1;339(1):1-13. doi: 10.1016/j.ydbio.2009.11.036. Epub 2009 Dec 28.


The tyrosine kinase Stitcher activates Grainy head and epidermal wound healing in Drosophila.

Wang S, Tsarouhas V, Xylourgidis N, Sabri N, Tiklová K, Nautiyal N, Gallio M, Samakovlis C.

Nat Cell Biol. 2009 Jul;11(7):890-5. doi: 10.1038/ncb1898. Epub 2009 Jun 14.


COPI vesicle transport is a common requirement for tube expansion in Drosophila.

Jayaram SA, Senti KA, Tiklová K, Tsarouhas V, Hemphälä J, Samakovlis C.

PLoS One. 2008 Apr 9;3(4):e1964. doi: 10.1371/journal.pone.0001964.


Regulation of the Drosophila hypoxia-inducible factor alpha Sima by CRM1-dependent nuclear export.

Romero NM, Irisarri M, Roth P, Cauerhff A, Samakovlis C, Wappner P.

Mol Cell Biol. 2008 May;28(10):3410-23. doi: 10.1128/MCB.01027-07. Epub 2008 Mar 10.


Distinct functions of the Drosophila Nup153 and Nup214 FG domains in nuclear protein transport.

Sabri N, Roth P, Xylourgidis N, Sadeghifar F, Adler J, Samakovlis C.

J Cell Biol. 2007 Aug 13;178(4):557-65. Epub 2007 Aug 6.


Sequential pulses of apical epithelial secretion and endocytosis drive airway maturation in Drosophila.

Tsarouhas V, Senti KA, Jayaram SA, Tiklová K, Hemphälä J, Adler J, Samakovlis C.

Dev Cell. 2007 Aug;13(2):214-25.


The nucleoporin Nup214 sequesters CRM1 at the nuclear rim and modulates NFkappaB activation in Drosophila.

Xylourgidis N, Roth P, Sabri N, Tsarouhas V, Samakovlis C.

J Cell Sci. 2006 Nov 1;119(Pt 21):4409-19. Epub 2006 Oct 10.


Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors.

Rusten TE, Rodahl LM, Pattni K, Englund C, Samakovlis C, Dove S, Brech A, Stenmark H.

Mol Biol Cell. 2006 Sep;17(9):3989-4001. Epub 2006 Jul 12.


Distinct functions of the leucine-rich repeat transmembrane proteins capricious and tartan in the Drosophila tracheal morphogenesis.

Krause C, Wolf C, Hemphälä J, Samakovlis C, Schuh R.

Dev Biol. 2006 Aug 1;296(1):253-64. Epub 2006 May 5.


Septate-junction-dependent luminal deposition of chitin deacetylases restricts tube elongation in the Drosophila trachea.

Wang S, Jayaram SA, Hemphälä J, Senti KA, Tsarouhas V, Jin H, Samakovlis C.

Curr Biol. 2006 Jan 24;16(2):180-5.


A transient luminal chitinous matrix is required to model epithelial tube diameter in the Drosophila trachea.

Tonning A, Hemphälä J, Tång E, Nannmark U, Samakovlis C, Uv A.

Dev Cell. 2005 Sep;9(3):423-30. Erratum in: Dev Cell. 2005 Nov;9(5):721.


Vilse, a conserved Rac/Cdc42 GAP mediating Robo repulsion in tracheal cells and axons.

Lundström A, Gallio M, Englund C, Steneberg P, Hemphälä J, Aspenström P, Keleman K, Falileeva L, Dickson BJ, Samakovlis C.

Genes Dev. 2004 Sep 1;18(17):2161-71.


Rhomboid 3 orchestrates Slit-independent repulsion of tracheal branches at the CNS midline.

Gallio M, Englund C, Kylsten P, Samakovlis C.

Development. 2004 Aug;131(15):3605-14. Epub 2004 Jun 30.


The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export.

Roth P, Xylourgidis N, Sabri N, Uv A, Fornerod M, Samakovlis C.

J Cell Biol. 2003 Nov 24;163(4):701-6.


Drosophila tracheal morphogenesis: intricate cellular solutions to basic plumbing problems.

Uv A, Cantera R, Samakovlis C.

Trends Cell Biol. 2003 Jun;13(6):301-9. Review.


Grainy head controls apical membrane growth and tube elongation in response to Branchless/FGF signalling.

Hemphälä J, Uv A, Cantera R, Bray S, Samakovlis C.

Development. 2003 Jan;130(2):249-58.


Attractive and repulsive functions of Slit are mediated by different receptors in the Drosophila trachea.

Englund C, Steneberg P, Falileeva L, Xylourgidis N, Samakovlis C.

Development. 2002 Nov;129(21):4941-51.


members only encodes a Drosophila nucleoporin required for rel protein import and immune response activation.

Uv AE, Roth P, Xylourgidis N, Wickberg A, Cantera R, Samakovlis C.

Genes Dev. 2000 Aug 1;14(15):1945-57.


Dpp and Notch specify the fusion cell fate in the dorsal branches of the Drosophila trachea.

Steneberg P, Hemphälä J, Samakovlis C.

Mech Dev. 1999 Sep;87(1-2):153-63.


adrift, a novel bnl-induced Drosophila gene, required for tracheal pathfinding into the CNS.

Englund C, Uv AE, Cantera R, Mathies LD, Krasnow MA, Samakovlis C.

Development. 1999 Apr;126(7):1505-14.


Translational readthrough in the hdc mRNA generates a novel branching inhibitor in the drosophila trachea.

Steneberg P, Englund C, Kronhamn J, Weaver TA, Samakovlis C.

Genes Dev. 1998 Apr 1;12(7):956-67.


Genetic control of epithelial tube fusion during Drosophila tracheal development.

Samakovlis C, Manning G, Steneberg P, Hacohen N, Cantera R, Krasnow MA.

Development. 1996 Nov;122(11):3531-6.


Helix pomatia lectin, an inducer of Drosophila immune response, binds to hemomucin, a novel surface mucin.

Theopold U, Samakovlis C, Erdjument-Bromage H, Dillon N, Axelsson B, Schmidt O, Tempst P, Hultmark D.

J Biol Chem. 1996 May 31;271(22):12708-15.


Development of the Drosophila tracheal system occurs by a series of morphologically distinct but genetically coupled branching events.

Samakovlis C, Hacohen N, Manning G, Sutherland DC, Guillemin K, Krasnow MA.

Development. 1996 May;122(5):1395-407.


The lysozyme locus in Drosophila melanogaster: an expanded gene family adapted for expression in the digestive tract.

Daffre S, Kylsten P, Samakovlis C, Hultmark D.

Mol Gen Genet. 1994 Jan;242(2):152-62.


kappa B-like motifs regulate the induction of immune genes in Drosophila.

Engström Y, Kadalayil L, Sun SC, Samakovlis C, Hultmark D, Faye I.

J Mol Biol. 1993 Jul 20;232(2):327-33.


In vitro induction of cecropin genes--an immune response in a Drosophila blood cell line.

Samakovlis C, Asling B, Boman HG, Gateff E, Hultmark D.

Biochem Biophys Res Commun. 1992 Nov 16;188(3):1169-75.


The lysozyme locus in Drosophila melanogaster: different genes are expressed in midgut and salivary glands.

Kylsten P, Kimbrell DA, Daffre S, Samakovlis C, Hultmark D.

Mol Gen Genet. 1992 Apr;232(3):335-43.


CecC, a cecropin gene expressed during metamorphosis in Drosophila pupae.

Tryselius Y, Samakovlis C, Kimbrell DA, Hultmark D.

Eur J Biochem. 1992 Feb 15;204(1):395-9.


Structure of TGF-beta 1-induced human immunoglobulin C alpha 1 and C alpha 2 germ-line transcripts.

Nilsson L, Islam KB, Olafsson O, Zalcberg I, Samakovlis C, Hammarström L, Smith CI, Sideras P.

Int Immunol. 1991 Nov;3(11):1107-15.


The andropin gene and its product, a male-specific antibacterial peptide in Drosophila melanogaster.

Samakovlis C, Kylsten P, Kimbrell DA, Engström A, Hultmark D.

EMBO J. 1991 Jan;10(1):163-9.


Insect immunity. Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides.

Wicker C, Reichhart JM, Hoffmann D, Hultmark D, Samakovlis C, Hoffmann JA.

J Biol Chem. 1990 Dec 25;265(36):22493-8.


The immune response in Drosophila: pattern of cecropin expression and biological activity.

Samakovlis C, Kimbrell DA, Kylsten P, Engström A, Hultmark D.

EMBO J. 1990 Sep;9(9):2969-76.


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