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Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals.

Tobe R, Carlson BA, Huh JH, Castro NP, Xu XM, Tsuji PA, Lee SG, Bang J, Na JW, Kong YY, Beaglehole D, Southon E, Seifried H, Tessarollo L, Salomon DS, Schweizer U, Gladyshev VN, Hatfield DL, Lee BJ.

Biochem J. 2016 Jul 15;473(14):2141-54. doi: 10.1042/BCJ20160393. Epub 2016 May 16.


Adaptation of Laser Microdissection Technique for the Study of a Spontaneous Metastatic Mammary Carcinoma Mouse Model by NanoString Technologies.

Castro NP, Merchant AS, Saylor KL, Anver MR, Salomon DS, Golubeva YG.

PLoS One. 2016 Apr 14;11(4):e0153270. doi: 10.1371/journal.pone.0153270. eCollection 2016.


Developmental signaling pathways regulating mammary stem cells and contributing to the etiology of triple-negative breast cancer.

Rangel MC, Bertolette D, Castro NP, Klauzinska M, Cuttitta F, Salomon DS.

Breast Cancer Res Treat. 2016 Apr;156(2):211-26. doi: 10.1007/s10549-016-3746-7. Epub 2016 Mar 11. Review.


Evaluation of glycosylated docetaxel-encapsulated liposomes prepared by remote loading under solubility gradient.

Shigehiro T, Zhai W, Vaidyanath A, Masuda J, Mizutani A, Kasai T, Murakami H, Hamada H, Salomon DS, Mikuni K, Seno Y, Mandai T, Seno M.

J Microencapsul. 2016;33(2):172-82. doi: 10.3109/02652048.2016.1144815. Epub 2016 Feb 17.


Cripto-1 ablation disrupts alveolar development in the mouse mammary gland through a progesterone receptor-mediated pathway.

Klauzinska M, McCurdy D, Rangel MC, Vaidyanath A, Castro NP, Shen MM, Gonzales M, Bertolette D, Bianco C, Callahan R, Salomon DS, Raafat A.

Am J Pathol. 2015 Nov;185(11):2907-22. doi: 10.1016/j.ajpath.2015.07.023. Epub 2015 Oct 1.


Dynamic regulation of the cancer stem cell compartment by Cripto-1 in colorectal cancer.

Francescangeli F, Contavalli P, De Angelis ML, Baiocchi M, Gambara G, Pagliuca A, Fiorenzano A, Prezioso C, Boe A, Todaro M, Stassi G, Castro NP, Watanabe K, Salomon DS, De Maria R, Minchiotti G, Zeuner A.

Cell Death Differ. 2015 Oct;22(10):1700-13. doi: 10.1038/cdd.2015.19. Epub 2015 Mar 20.


Cripto-1 in TNBC.

Castro NP, Salomon DS.

Aging (Albany NY). 2015 Aug;7(8):515-6. No abstract available.


Cripto-1 as a novel therapeutic target for triple negative breast cancer.

Castro NP, Fedorova-Abrams ND, Merchant AS, Rangel MC, Nagaoka T, Karasawa H, Klauzinska M, Hewitt SM, Biswas K, Sharan SK, Salomon DS.

Oncotarget. 2015 May 20;6(14):11910-29.


CRIPTO overexpression promotes mesenchymal differentiation in prostate carcinoma cells through parallel regulation of AKT and FGFR activities.

Terry S, El-Sayed IY, Destouches D, Maillé P, Nicolaiew N, Ploussard G, Semprez F, Pimpie C, Beltran H, Londono-Vallejo A, Allory Y, de la Taille A, Salomon DS, Vacherot F.

Oncotarget. 2015 May 20;6(14):11994-2008.


Efficient drug delivery of Paclitaxel glycoside: a novel solubility gradient encapsulation into liposomes coupled with immunoliposomes preparation.

Shigehiro T, Kasai T, Murakami M, Sekhar SC, Tominaga Y, Okada M, Kudoh T, Mizutani A, Murakami H, Salomon DS, Mikuni K, Mandai T, Hamada H, Seno M.

PLoS One. 2014 Sep 29;9(9):e107976. doi: 10.1371/journal.pone.0107976. eCollection 2014.


Characterization of cancer stem-like cells derived from mouse induced pluripotent stem cells transformed by tumor-derived extracellular vesicles.

Yan T, Mizutani A, Chen L, Takaki M, Hiramoto Y, Matsuda S, Shigehiro T, Kasai T, Kudoh T, Murakami H, Masuda J, Hendrix MJ, Strizzi L, Salomon DS, Fu L, Seno M.

J Cancer. 2014 Jul 5;5(7):572-84. doi: 10.7150/jca.8865. eCollection 2014.


CRIPTO1 expression in EGFR-mutant NSCLC elicits intrinsic EGFR-inhibitor resistance.

Park KS, Raffeld M, Moon YW, Xi L, Bianco C, Pham T, Lee LC, Mitsudomi T, Yatabe Y, Okamoto I, Subramaniam D, Mok T, Rosell R, Luo J, Salomon DS, Wang Y, Giaccone G.

J Clin Invest. 2014 Jul;124(7):3003-15. doi: 10.1172/JCI73048. Epub 2014 Jun 9.


Mouse induced pluripotent stem cell microenvironment generates epithelial-mesenchymal transition in mouse Lewis lung cancer cells.

Chen L, Mizutani A, Kasai T, Yan T, Jin G, Vaidyanath A, El-Aarag BY, Liu Y, Kudoh T, Salomon DS, Fu L, Seno M.

Am J Cancer Res. 2014 Jan 15;4(1):80-8. eCollection 2014.


Cancer stem cells maintain a hierarchy of differentiation by creating their niche.

Matsuda S, Yan T, Mizutani A, Sota T, Hiramoto Y, Prieto-Vila M, Chen L, Satoh A, Kudoh T, Kasai T, Murakami H, Fu L, Salomon DS, Seno M.

Int J Cancer. 2014 Jul 1;135(1):27-36. doi: 10.1002/ijc.28648. Epub 2013 Dec 9.


SCNH2 is a novel apelinergic family member acting as a potent mitogenic and chemotactic factor for both endothelial and epithelial cells.

Fang C, Avis I, Bianco C, Held N, Morris J, Ylaya K, Hewitt SM, Aplin AC, Nicosia RF, Fung LA, Lewis JD, Stetler-Stevenson WG, Salomon DS, Cuttitta F.

Open J Clin Diagn. 2013 Jun;3(2):37-51.


Identification of caveolin-1 as a potential causative factor in the generation of trastuzumab resistance in breast cancer cells.

Sekhar SC, Kasai T, Satoh A, Shigehiro T, Mizutani A, Murakami H, El-Aarag BY, Salomon DS, Massaguer A, de Llorens R, Seno M.

J Cancer. 2013 Jun 21;4(5):391-401. doi: 10.7150/jca.6470. Print 2013.


Embryonic stem cells are redirected to non-tumorigenic epithelial cell fate by interaction with the mammary microenvironment.

Boulanger CA, Bruno RD, Mack DL, Gonzales M, Castro NP, Salomon DS, Smith GH.

PLoS One. 2013 Apr 26;8(4):e62019. doi: 10.1371/journal.pone.0062019. Print 2013.


The significance of a Cripto-1 positive subpopulation of human melanoma cells exhibiting stem cell-like characteristics.

Strizzi L, Margaryan NV, Gilgur A, Hardy KM, Normanno N, Salomon DS, Hendrix MJ.

Cell Cycle. 2013 May 1;12(9):1450-6. doi: 10.4161/cc.24601. Epub 2013 Apr 10.


A small molecule (pluripotin) as a tool for studying cancer stem cell biology: proof of concept.

Mertins SD, Scudiero DA, Hollingshead MG, Divelbiss RD Jr, Alley MC, Monks A, Covell DG, Hite KM, Salomon DS, Niederhuber JE.

PLoS One. 2013;8(2):e57099. doi: 10.1371/journal.pone.0057099. Epub 2013 Feb 21.


Eosinophil cationic protein enhances stabilization of β-catenin during cardiomyocyte differentiation in P19CL6 embryonal carcinoma cells.

Jin G, Mizutani A, Fukuda T, Otani T, Yan T, Prieto Vila M, Murakami H, Kudoh T, Hirohata S, Kasai T, Salomon DS, Seno M.

Mol Biol Rep. 2013 Apr;40(4):3165-71. doi: 10.1007/s11033-012-2390-5. Epub 2012 Dec 28.


Regulation of human Cripto-1 expression by nuclear receptors and DNA promoter methylation in human embryonal and breast cancer cells.

Bianco C, Castro NP, Baraty C, Rollman K, Held N, Rangel MC, Karasawa H, Gonzales M, Strizzi L, Salomon DS.

J Cell Physiol. 2013 Jun;228(6):1174-88. doi: 10.1002/jcp.24271.


Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors.

Nagaoka T, Karasawa H, Turbyville T, Rangel MC, Castro NP, Gonzales M, Baker A, Seno M, Lockett S, Greer YE, Rubin JS, Salomon DS, Bianco C.

Cell Signal. 2013 Jan;25(1):178-89. doi: 10.1016/j.cellsig.2012.09.024. Epub 2012 Sep 27.


Eosinophil cationic protein enhances cardiomyocyte differentiation of P19CL6 embryonal carcinoma cells by stimulating the FGF receptor signaling pathway.

Jin G, Mizutani A, Fukuda T, Chen L, Nakanishi K, Yan T, Kudoh T, Hirohata S, Kasai T, Murakami H, Salomon DS, Seno M.

Growth Factors. 2012 Oct;30(5):344-55. Epub 2012 Jul 31.


Role of Cripto-1 during epithelial-to-mesenchymal transition in development and cancer.

Rangel MC, Karasawa H, Castro NP, Nagaoka T, Salomon DS, Bianco C.

Am J Pathol. 2012 Jun;180(6):2188-200. doi: 10.1016/j.ajpath.2012.02.031. Epub 2012 Apr 26. Review.


A model of cancer stem cells derived from mouse induced pluripotent stem cells.

Chen L, Kasai T, Li Y, Sugii Y, Jin G, Okada M, Vaidyanath A, Mizutani A, Satoh A, Kudoh T, Hendrix MJ, Salomon DS, Fu L, Seno M.

PLoS One. 2012;7(4):e33544. doi: 10.1371/journal.pone.0033544. Epub 2012 Apr 12.


An evolving web of signaling networks regulated by Cripto-1.

Nagaoka T, Karasawa H, Castro NP, Rangel MC, Salomon DS, Bianco C.

Growth Factors. 2012 Feb;30(1):13-21. doi: 10.3109/08977194.2011.641962. Epub 2011 Dec 12. Review.


Expression and functional role of CRIPTO-1 in cutaneous melanoma.

De Luca A, Lamura L, Strizzi L, Roma C, D'Antonio A, Margaryan N, Pirozzi G, Hsu MY, Botti G, Mari E, Hendrix MJ, Salomon DS, Normanno N.

Br J Cancer. 2011 Sep 27;105(7):1030-8. doi: 10.1038/bjc.2011.324. Epub 2011 Aug 23.


miR-31 in cancer: location matters.

Stuelten CH, Salomon DS.

Cell Cycle. 2010 Dec 1;9(23):4608-9. No abstract available.


Targeting the embryonic gene Cripto-1 in cancer and beyond.

Bianco C, Salomon DS.

Expert Opin Ther Pat. 2010 Dec;20(12):1739-49. doi: 10.1517/13543776.2010.530659. Epub 2010 Nov 13. Review.


Intercellular transfer regulation of the paracrine activity of GPI-anchored Cripto-1 as a Nodal co-receptor.

Watanabe K, Salomon DS.

Biochem Biophys Res Commun. 2010 Dec 3;403(1):108-13. doi: 10.1016/j.bbrc.2010.10.128. Epub 2010 Nov 3.


Cripto-1: an embryonic gene that promotes tumorigenesis.

de Castro NP, Rangel MC, Nagaoka T, Salomon DS, Bianco C.

Future Oncol. 2010 Jul;6(7):1127-42. doi: 10.2217/fon.10.68. Review.


Role of Cripto-1 in stem cell maintenance and malignant progression.

Bianco C, Rangel MC, Castro NP, Nagaoka T, Rollman K, Gonzales M, Salomon DS.

Am J Pathol. 2010 Aug;177(2):532-40. doi: 10.2353/ajpath.2010.100102. Epub 2010 Jul 8. Review.


Cripto-1 is a cell surface marker for a tumorigenic, undifferentiated subpopulation in human embryonal carcinoma cells.

Watanabe K, Meyer MJ, Strizzi L, Lee JM, Gonzales M, Bianco C, Nagaoka T, Farid SS, Margaryan N, Hendrix MJ, Vonderhaar BK, Salomon DS.

Stem Cells. 2010 Aug;28(8):1303-14. doi: 10.1002/stem.463.


ErbB/EGF signaling and EMT in mammary development and breast cancer.

Hardy KM, Booth BW, Hendrix MJ, Salomon DS, Strizzi L.

J Mammary Gland Biol Neoplasia. 2010 Jun;15(2):191-9. doi: 10.1007/s10911-010-9172-2. Epub 2010 Apr 6. Review.


Novel and simple loading procedure of cisplatin into liposomes and targeting tumor endothelial cells.

Hirai M, Minematsu H, Hiramatsu Y, Kitagawa H, Otani T, Iwashita S, Kudoh T, Chen L, Li Y, Okada M, Salomon DS, Igarashi K, Chikuma M, Seno M.

Int J Pharm. 2010 May 31;391(1-2):274-83. doi: 10.1016/j.ijpharm.2010.02.030. Epub 2010 Mar 6.


Enhancement of Notch receptor maturation and signaling sensitivity by Cripto-1.

Watanabe K, Nagaoka T, Lee JM, Bianco C, Gonzales M, Castro NP, Rangel MC, Sakamoto K, Sun Y, Callahan R, Salomon DS.

J Cell Biol. 2009 Nov 2;187(3):343-53. doi: 10.1083/jcb.200905105.


Production of biologically active IgG hinge-tag soluble epidermal growth factor receptors (ErbB).

Otani T, Hashizume T, Nagaoka T, Fukuda T, Tang CK, Salomon DS, Seno M.

Biotechnol Lett. 2010 Mar;32(3):361-6. doi: 10.1007/s10529-009-0160-9. Epub 2009 Nov 7.


Cripto-1 is required for hypoxia to induce cardiac differentiation of mouse embryonic stem cells.

Bianco C, Cotten C, Lonardo E, Strizzi L, Baraty C, Mancino M, Gonzales M, Watanabe K, Nagaoka T, Berry C, Arai AE, Minchiotti G, Salomon DS.

Am J Pathol. 2009 Nov;175(5):2146-58. doi: 10.2353/ajpath.2009.090218. Epub 2009 Oct 15.


Human Cripto-1 as a target for a cancer vaccine: WO2008040759.

Bianco C, Salomon DS.

Expert Opin Ther Pat. 2009 Feb;19(2):141-4. doi: 10.1517/13543770802646956. Review.


Neuronal guidance protein Netrin-1 induces differentiation in human embryonal carcinoma cells.

Mancino M, Esposito C, Watanabe K, Nagaoka T, Gonzales M, Bianco C, Normanno N, Salomon DS, Strizzi L.

Cancer Res. 2009 Mar 1;69(5):1717-21. doi: 10.1158/0008-5472.CAN-08-2985. Epub 2009 Feb 17.


Msx2 induces epithelial-mesenchymal transition in mouse mammary epithelial cells through upregulation of Cripto-1.

di Bari MG, Ginsburg E, Plant J, Strizzi L, Salomon DS, Vonderhaar BK.

J Cell Physiol. 2009 Jun;219(3):659-66. doi: 10.1002/jcp.21712.


Emerging roles of nodal and Cripto-1: from embryogenesis to breast cancer progression.

Strizzi L, Postovit LM, Margaryan NV, Seftor EA, Abbott DE, Seftor RE, Salomon DS, Hendrix MJ.

Breast Dis. 2008;29:91-103.


Activation of a Nodal-independent signaling pathway by Cripto-1 mutants with impaired activation of a Nodal-dependent signaling pathway.

Bianco C, Mysliwiec M, Watanabe K, Mancino M, Nagaoka T, Gonzales M, Salomon DS.

FEBS Lett. 2008 Dec 10;582(29):3997-4002. doi: 10.1016/j.febslet.2008.10.052. Epub 2008 Nov 18.


Characterization of the glycosylphosphatidylinositol-anchor signal sequence of human Cryptic with a hydrophilic extension.

Watanabe K, Nagaoka T, Strizzi L, Mancino M, Gonzales M, Bianco C, Salomon DS.

Biochim Biophys Acta. 2008 Dec;1778(12):2671-81. doi: 10.1016/j.bbamem.2008.09.011. Epub 2008 Oct 1.


Potential for cripto-1 in defining stem cell-like characteristics in human malignant melanoma.

Strizzi L, Abbott DE, Salomon DS, Hendrix MJ.

Cell Cycle. 2008 Jul 1;7(13):1931-5. Epub 2008 May 5.


Smad2 functions as a co-activator of canonical Wnt/beta-catenin signaling pathway independent of Smad4 through histone acetyltransferase activity of p300.

Hirota M, Watanabe K, Hamada S, Sun Y, Strizzi L, Mancino M, Nagaoka T, Gonzales M, Seno M, Bianco C, Salomon DS.

Cell Signal. 2008 Sep;20(9):1632-41. doi: 10.1016/j.cellsig.2008.05.003. Epub 2008 May 18.


A betacellulin mutant promotes differentiation of pancreatic acinar AR42J cells into insulin-producing cells with low affinity of binding to ErbB1.

Nagaoka T, Fukuda T, Hashizume T, Nishiyama T, Tada H, Yamada H, Salomon DS, Yamada S, Kojima I, Seno M.

J Mol Biol. 2008 Jun 27;380(1):83-94. doi: 10.1016/j.jmb.2008.03.054. Epub 2008 Apr 3.


Cell type dependent endocytic internalization of ErbB2 with an artificial peptide ligand that binds to ErbB2.

Hashizume T, Fukuda T, Nagaoka T, Tada H, Yamada H, Watanabe K, Salomon DS, Seno M.

Cell Biol Int. 2008 Jul;32(7):814-26. doi: 10.1016/j.cellbi.2008.03.012. Epub 2008 Mar 29.


Netrin-1 can affect morphogenesis and differentiation of the mouse mammary gland.

Strizzi L, Mancino M, Bianco C, Raafat A, Gonzales M, Booth BW, Watanabe K, Nagaoka T, Mack DL, Howard B, Callahan R, Smith GH, Salomon DS.

J Cell Physiol. 2008 Sep;216(3):824-34. doi: 10.1002/jcp.21462.

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